Non-celiac gluten sensitivity: questions still to be answered despite increasing awareness (original) (raw)
Volta U, de Giorgio R . New understanding of gluten sensitivity. Nat Rev Gastroenterol Hepatol 2012; 9: 295–299. ArticleCASPubMed Google Scholar
Sapone A, Bai JC, Ciacci C, Dolinsek J, Green PH, Hadijvassiliou M et al. Spectrum of gluten-related disorders: consensus on new nomenclature and classification. BMC Med 2012; 10: 13. ArticlePubMedPubMed Central Google Scholar
Gibert A, Espadaler M, Angel Canela M, Sánchez A, Vaqué C, Rafecas M . Consumption of gluten-free products: should be the threshold value for traces amounts of gluten be at 20, 100 or 200 p.p.m.? Eur J Gastroenterol Hepatol 2006; 18: 1187–1195. ArticleCASPubMed Google Scholar
Belderok B . Developments in bread-making processes. Plant Food Hum Nutr 2000; 55: 1–86. ArticleCAS Google Scholar
Gobbetti M, Rizzello CG, Di Cagno R, de Angelis M . Sordough lactobacilli and coeliac disease. Food Microbiol 2007; 24: 187–196. ArticleCASPubMed Google Scholar
Inonata N . Wheat allergy. Cur Opin Aller Clin Immunol 2009; 9: 238–243. Article Google Scholar
Blomfeldt TO, Kuktaite R, Johansson E, Hedenqvist MS . Mechanical properties and network structure of wheat gluten forms. Biomacromolecules 2011; 12: 1707–1715. ArticleCASPubMed Google Scholar
Fraser JS, Engel W, Ellis HJ, Moodie SJ, Pollock EL, Wieser H et al. Coeliac disease: in vivo toxicity of the putative immunodominant epitope. Gut 2003; 52: 1698–1702. ArticleCASPubMedPubMed Central Google Scholar
Drago S, El Asmar R, Di Pierro M, Clemente MG, Tripathi A, Sapone A et al. Gliadin, zonulin, and gut permeability: effects on celiac and non-celiac mucosa and intestinal cell lines. Scand J Gastroenterol 2006; 41: 408–419. ArticleCASPubMed Google Scholar
Dolfini E, Roncoroni L, Elli L, Fumagalli C, Colombo R, Ramponi S et al. Cytoskeleton reorganization and ultrastructural damage induced by gliadin in a three-dimensional in vitro model. World J Gastroenterol 2005; 11: 7597–7601. ArticleCASPubMedPubMed Central Google Scholar
Cooper BT, Holmes GK, Ferguson R, Thompson RA, Allan RN, Cooke WT . Gluten-sensitive diarrhea without evidence of celiac disease. Gastroenterology 1980; 79: 801–806. CASPubMed Google Scholar
Kaukinen K, Turjanmaa K, Mäki M, Partanen J, Venäläinen R, Reunala T et al. Intolerance to cerealsis not specific for celiac disease. Scand J Gastroenterol 2000; 35: 942–946. ArticleCASPubMed Google Scholar
Verdu EF, Armstrong D, Murray JA . Between celiac disease and irritable bowel syndrome: the ‘no man's land’ of gluten sensitivity. Am J Gastroenterol 2009; 104: 1587–1594. ArticlePubMedPubMed Central Google Scholar
Troncone R, Jabri B . Coeliac disease and gluten sensitivity. J Intern Med 2011; 269: 582–590. ArticleCASPubMed Google Scholar
Di Sabatino A, Corazza GR . Non-celiac gluten sensitivity: sense or sensibility? Ann Intern Med 2012; 156: 309–311. ArticlePubMed Google Scholar
Lundin KEA, Alaedini A . Non-celiac gluten sensitivity. Gastrointest Endoscopy Clin N Am 2012; 22: 723–734. Article Google Scholar
Brown AC . Gluten sensitivity: problems of an emerging condition separate from celiac disease. Expert Rev Gastroenterol Hepatol 2012; 6: 41–53. Google Scholar
Godlee F . Gluten sensitivity: real or not? BMJ 2012; 345: e8450. Article Google Scholar
Anonymus patient, Rostami K, Hogg-Kollars S . Non-coeliac gluten sensitivity: a patient's journey. BMJ 2012; 345: e7982. Article Google Scholar
Sollid LM, Jabri B . Triggers and drivers of autoimmunity: lessons from celiac disease. Nat Rev Immunol 2013; 13: 294–302. ArticleCASPubMed Google Scholar
Crome SQ, Wang AY, Levings MK . Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol 2010; 159: 109–119. ArticleCASPubMedPubMed Central Google Scholar
Bilate AM, Lafaille JJ . Induced CD4+ FoxP3+ regulatory T cells in immune tolerance. Annu Rev Immunol 2012: 30: 733–758. ArticleCASPubMed Google Scholar
Castellanos-Rubio A, Santin I, Irastorza I, Castaño L, Carlos Vitoria J, Ramon Bilbao J . TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin. Autoimmunity 2009; 42: 69–73. ArticleCASPubMed Google Scholar
Harris KM, Fasano A, Mann DL . Cutting edge: IL-1 controls the IL-23 response induced by gliadin, the etiologic agent in celiac disease. J Immunol 2008; 181: 4457–4460. ArticleCASPubMed Google Scholar
Monteleone I, Pallone F, Monteleone G . Interleukin-23 and Th17 cells in the control of gut inflammation. Mediators Inflamm 2009; 2009: 297645. ArticlePubMedPubMed Central Google Scholar
Monteleone I, Sarra M, del Vecchio BG, Paoluzi OA, Franze E, Fina D et al. Characterization of IL-17A-producing cells in celiac disease mucosa. J Immunol 2010; 184: 2211–2218. ArticleCASPubMed Google Scholar
Sapone A, Lammers K, Casolaro V, Cammarota M, Giuliano MT, de Rosa M et al. Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity. BMC Med 2011; 9: 23. ArticleCASPubMedPubMed Central Google Scholar
Sapone A, Lammers KM, Mazzarella G, Mikhailenko I, Carteni M, Casolaro V et al. Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease. Int Arch AllergyImmunol 2010; 152: 75–80. ArticleCAS Google Scholar
Vorobjova T, Uibo O, Heilman K, Rägo T, Honkanen J, Vaarala O et al. Increased FOXP3 expression in small-bowel mucosa of children with coeliac disease and type I diabetes mellitus. Scand J Gastroenterol 2009; 44: 422–430. ArticleCASPubMed Google Scholar
Hansson T, Ulfgren AK, Lindroos E, DannAEus A, Dahlbom I, Klareskog L . Transforming growth factor-beta (TGF-beta) and tissue transglutaminase expression in the small intestine in children with coeliac disease. Scand J Immunol 2002; 56: 530–537. ArticleCASPubMed Google Scholar
Schuppan D . Current concepts of celiac disease pathogenesis. Gastroenterology 2000; 119: 234–242. ArticleCASPubMed Google Scholar
Biesiekierski JR, Newnham ED, Irving PM, Barrett JS, Haines M, Doecke JD et al. Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blind randomized placebo-controlled trial. Am J Gastroenterol 2011; 106: 508–514. ArticleCASPubMed Google Scholar
Vaquez-Roque MI, Camilleri M, Smyrk T, Murray JA, Marietta E, O'Neill J et al. A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function. Gastroenterology 2013; 144: 903–911. Article Google Scholar
Verdu EF, Huang X, Natividad J, Lu J, Blennerhassett PA, David CS et al. Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice. Am J Physiol Gastrointest Liver Physiol 2008; 294: G217–G225. ArticleCASPubMed Google Scholar
Natividad JM, Huang X, Slack E, Jury J, Sanz Y, David C et al. Host responses to intestinal microbial antigensin gluten sensitive mice. PLos ONE 2009; 4: e6472. ArticlePubMedPubMed Central Google Scholar
Junker Y, Zeissig S, Kim SJ, Barisani D, Wieser H, Leffler DA et al. Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4. J Exp Med 2012; 209: 2395–2408. ArticleCASPubMedPubMed Central Google Scholar
Gibson PR, Sheperd SJ . Food choice as a key management strategy for functional gastrointestinal symptoms. Am J Gastroenterol 2012; 107: 657–666. ArticleCASPubMed Google Scholar
Corazza GR, Frazzoni M, Strocchi A, Prati C, Sarchielli P, Capelli M et al. Alimentary exorphin actions on motility and hormonal secretion of gastrointestinal tract. In: Fraioli F, Isidori A, Mazzetti M (ed.). Opioid Peptides in the Periphery. Amsterdam: Elsevier Sciences Publisher, 1984: 243–247. Google Scholar
Suarez FL . Savaiano DA, Levitt MD . A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. N Engl J Med 1995; 333: 1–4. ArticleCASPubMed Google Scholar
Carroccio A, Mansueto P, Iacono G, Soresi M, D'Alcamo A, Cavataio F et al. Non-celiac wheat sensitivity diagnosed by double-blind placebo-controlled challenge: exploring a new clinical entity. Am J Gastroenterol 2012; 107: 1898–1906. ArticlePubMed Google Scholar
Volta U, Tovoli F, Cicola R, Parisi C, Fabbri A, Piscaglia M et al. Serological tests in gluten sensitività (nonceliac gluten intolerance). J Clin Gastroenterol 2012; 46: 680–685. ArticleCASPubMed Google Scholar
Volta U . Indagine su sensibilità al glutine non celiaca: risultati preliminari. Celiachia Notizie 2013, 1: 58–60. Google Scholar
Dezi R, Niveloni S, Sugai E, Pedreira S, Smecuol E, Vazquez H et al. Gluten sensitivity in the rectal mucosa of first-degree relatives of celiac disease patients. Am J Gastroenterol 1997; 92: 1326–1330. CASPubMed Google Scholar
Bizzaro N, Tozzoli R, Villalta D, Fabris M, Tonutti E . Cutting-edge issues in celiac disease and in gluten intolerance. Clin Rev Allerg Immunol 2012; 42: 279–287. ArticleCAS Google Scholar
Volta U, Granito A, Parisi C, Fabbri A, Fiorini E, Piscaglia M et al. Deamidated gliadin peptide antibodies as a routine test for celiac disease: a prospective analysis. J Clin Gastroenterol 2010; 44: 186–190. ArticlePubMed Google Scholar
Volta U, Corazza GR, Frisoni M, Valentini RA, Molinaro N, Bianchi FB et al. IgA antigliadin antibodies and persistence of jejunal lesions in adult celiac disease. Digestion 1990; 47: 111–114. ArticleCASPubMed Google Scholar
Oberhuber G, Granditsch G, Vogelsang H . The histopathology of coeliac disease: time for a stndardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999; 11: 1185–1194. ArticleCAS Google Scholar
Not T, Ziberna F, Vatta S, Quaglia S, Martelossi S, Villanacci V et al. Cryptic genetic gluten intolerance revealed by intestinal antitransglutaminase antibodies and response to gluten-free diet. Gut 2011; 60: 1487–1493. ArticleCAS Google Scholar