Infectivity of Chloroquine Resistant Plasmodium berghei to Anopheles stephensi enhanced by Chloroquine (original) (raw)

Nature volume 223, pages 635–636 (1969)Cite this article

Abstract

DRUG resistance is an increasing problem in parts of South America and South-East Asia where numerous strains of the malignant tertian malaria parasite, Plasmodium falciparum, are refractory to chloroquine and other widely used antimalarials1. The rapidity with which new chloroquine-resistant strains are being recognized suggests that they may have, as well as drug resistance, some biological advantage over the accompanying sensitive falciparum parasites either in the vertebrate host (man) or the invertebrate host (certain species of Anopheles mosquitoes).

This is a preview of subscription content, access via your institution

Access options

Subscribe to this journal

Receive 51 print issues and online access

$199.00 per year

only $3.90 per issue

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Additional access options:

Similar content being viewed by others

References

  1. Peters, W., Trans. Roy. Soc. Trop. Med. Hyg., 63, 25 (1969).
    Article CAS Google Scholar
  2. Peters, W., Trop. Dis. Bull., 64, 1145 (1967).
    CAS PubMed Google Scholar
  3. Diggens, S. M., and Gregory, K., Trans. Roy. Soc. Trop. Med. Hyg., 63, 7 (1969).
    CAS PubMed Google Scholar
  4. Warhurst, D. C., and Killiek-Kendrick, R., Nature, 213, 1048 (1967).
    Article ADS CAS Google Scholar
  5. Warhurst, D. C., and Folwell, R. O., Ann. Trop. Med. Parasitol., 62, 349 (1968).
    Article CAS Google Scholar
  6. Covell, G., Coatney, G. R., Field, J. W., and Singh, J., Chemotherapy of Malaria, WHO Monog., Ser. No. 27 (1955).
  7. Rieckmann, K. H., McNamara, J. V., Frischer, H., Stockert, T. A., Carson, P. E., and Powell, R. D., Bull. WHO, 38, 625 (1968).
    CAS PubMed Google Scholar

Download references

Author information

Authors and Affiliations

  1. Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, L3 5QA
    A. E. RAMKARAN & W. PETERS

Authors

  1. A. E. RAMKARAN
  2. W. PETERS

Rights and permissions

About this article

Cite this article

RAMKARAN, A., PETERS, W. Infectivity of Chloroquine Resistant Plasmodium berghei to Anopheles stephensi enhanced by Chloroquine.Nature 223, 635–636 (1969). https://doi.org/10.1038/223635a0

Download citation

This article is cited by