Alkaloids and Flavonoids from Peanut Skins (original) (raw)
Planta Med 2001; 67(4): 345-349
DOI: 10.1055/s-2001-14319
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York
Hongxiang Lou1,*, Huiqing Yuan1 , Yoshimitsu Yamazaki2 , Tsutomu Sasaki2 , Syuichi Oka2
- 1 School of Pharmaceutical Sciences, Shandong University, Jinan, P. R. China
- 2 National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan
Publication History
June 30, 2000
August 26, 2000
Publication Date:
31 December 2001 (online)
Abstract
Separation of the water-soluble fraction of peanut skins led to the isolation of 8 flavonoids and two novel indole alkaloids. Two new flavonoid glycosides have been identified as isorhamnetin 3-_O_-[2-_O_-β-glucopyranosyl-6-_O_-α-rhamnopyranosyl]-β-glucopyranoside and 3′,5,7-trihydroxyisoflavone-4′-methoxy-3′-_O_-β-glucopyranoside. Two alkaloids are 2-methoxyl-3-(3-indolyl)-propionic acid and 2-hydroxyl-3-[3-(1-_N_-methyl)-indolyl]-propionic acid. These isolated flavonoids were evaluated for their free radical scavenging activity and protein glycation inhibitory effects.
Key words
Arachis hypogaea - Leguminosae - peanut skins - flavonoids - indole alkaloids - free radical scavenging - protein glycation - inhibition
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Dr. Lou HongxiangProfessor of Natural Products Chemistry
School of Pharmaceutical Sciences
Shandong University
Jinan 250012
Shandong Province
P. R. China
Email: hxlou@jn-public.sd.cninfo.net
Fax: 86-0531-2942373