Selenium Level and Glutathione Peroxidase Activity in Plasma, Erythrocytes and Platelets of Healthy Japanese Volunteers (original) (raw)

Abstract

The purpose of this study was to determine both the seleni-um (Se) level and glutathione peroxidase (GSH-Px) activity in plasma, erythrocytes and platelets from 51 healthy Japanese individuals. The Se levels (mean±SD) of plasma, erythrocytes and platelets were 117.4±15.7 μg/L, 0.954±0.159 μg/g hemoglobin, and 4.93±1.52 μg/mg protein, respectively, and GSH-Px activity was 318±50 U/L, 18.0±5.0 U/g he-moglobin, and 0.142 ±0.035 U/mg protein, respectively. There was a negative correlation between age and the platelet Se level in men (γ=-0.761, p<0.001), and a positive correlation between the plasma and platelet GSH-Px activities in women (γ=0.663, p<0.001).