Phorate (original) (raw)

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Phorate
Names
Preferred IUPAC name O,_O_-Diethyl _S_-[(ethylsulfanyl)methyl] phosphorodithioate
Other namesThimet (trademark)3911 (trademark)
Identifiers
CAS Number 298-02-2 checkY
3D model (JSmol) Interactive image
ChEBI CHEBI:38764 ☒N
ChEMBL ChEMBL510014 ☒N
ChemSpider 4626 checkY
ECHA InfoCard 100.005.503 Edit this at Wikidata
PubChem CID 4790
UNII 3W54X3W9IV checkY
CompTox Dashboard (EPA) DTXSID4032459 Edit this at Wikidata
InChI InChI=1S/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3 checkYKey: BULVZWIRKLYCBC-UHFFFAOYSA-N checkYInChI=1/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3Key: BULVZWIRKLYCBC-UHFFFAOYAA
SMILES S=P(OCC)(SCSCC)OCC
Properties
Chemical formula C7H17O2PS3
Molar mass 260.36 g·mol−1
Appearance Colorless liquid
Odor Skunk-like[1]
Density 1.16 g/mL
Melting point −43 °C; −45 °F; 230 K[1]
Boiling point 118-120°C (2.0 mm Hg)[2]
Solubility in water 0.005% (20°C)[1]
Vapor pressure 0.0008 mmHg (20°C)[1]
Hazards
Flash point 160 °C; 320 °F; 433 K (open cup)[1]
NIOSH (US health exposure limits):
PEL (Permissible) none[1]
REL (Recommended) TWA 0.05 mg/m3 ST 0.2 mg/m3 [skin][1]
IDLH (Immediate danger) N.D.[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ☒N verify (what is checkY☒N ?) Infobox references

Chemical compound

Phorate is an organophosphate used as an insecticide and acaricide.

At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammals including humans. It inhibits acetylcholinesterase and butyrylcholinesterase.[3]

Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.[3]

Phorate (Thimate) is absorbed readily through all ways. Its toxicity is high. Oral LD50 to rats is 1.1 – 3.2 mg/kg, to mice 3.5 – 6.5 mg/kg (technical phorate). Similar values has been found out to birds.[3]

  1. ^ a b c d e f g h NIOSH Pocket Guide to Chemical Hazards. "#0502". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ Farm Chemicals Handbook, Meister Publishing Co., Willoughby, OH (1991)
  3. ^ a b c "Data sheets on pesticides No. 75 – Phorate". Archived from the original on 2014-07-02. Retrieved 2011-07-31.