Predictors of anxiety and depression in people with colorectal cancer (original) (raw)
Gray, Nicola M., Hall, Susan J., Browne, Susan 
ORCID: https://orcid.org/0000-0003-1785-1429, Johnston, Marie, Lee, Amanda J., Macleod, Una, Mitchell, Elizabeth D., Samuel, Leslie and Campbell, Neil C.(2014) Predictors of anxiety and depression in people with colorectal cancer.Supportive Care in Cancer, 22(2), pp. 307-314. (doi: 10.1007/s00520-013-1963-8) (PMID:24077745)
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Abstract
Background: People living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these. Methods: Four hundred and ninety-six people with colorectal cancer completed the Hospital Anxiety and Depression Scale (HADS). Data on functioning, symptoms, illness perceptions and social difficulties were collected by questionnaire. Case-note-identified disease, treatment and co-morbidity data were recorded. Multiple logistic regression identified factors independently predictive of anxiety and depression caseness.
Results: Self-reported history of anxiety/depression predicted anxiety but not depression caseness. Depression caseness predicted anxiety caseness (p = 0.043), as did poorer self-reported cognitive functioning (p = 0.001), dyspnoea (p = 0.015) or diarrhoea (p = 0.021), reporting a high negative life and emotional impact (p < 0.001) and having difficulties with finance (p = 0.007). Having neo-adjuvant radiotherapy increased the odds of depression caseness (p = 0.007), as did poorer physical (p = 0.007), cognitive (p < 0.001) and social (p < 0.001) functioning, having constipation (p = 0.011), reporting a high negative life and emotional impact (p < 0.001), having difficulties with personal care (p = 0.022) and communicating with others (p = 0.014). Conclusion: Levels of anxiety caseness were similar to those of non-clinical samples, but depression caseness was higher, particularly in those who had received neo-adjuvant radiotherapy. Most factors associated with possible or probable depression may be modified with appropriate intervention.| Item Type: | Articles |
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| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Browne, Dr Susan |
| Authors: | Gray, N. M., Hall, S. J., Browne, S., Johnston, M., Lee, A. J., Macleod, U., Mitchell, E. D., Samuel, L., and Campbell, N. C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary CareCollege of Medical Veterinary and Life Sciences > School of Health & Wellbeing > MRC/CSO SPHSU |
| Journal Name: | Supportive Care in Cancer |
| Publisher: | Springer Berlin Heidelberg |
| ISSN: | 0941-4355 |
| ISSN (Online): | 1433-7339 |
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Deposit and Record Details
| ID Code: | 106972 |
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| Depositing User: | Miss Dawn Pike |
| Datestamp: | 02 Jun 2015 16:50 |
| Last Modified: | 28 Mar 2025 22:19 |
| Date of first online publication: | 1 February 2014 |