Lifting the differentiation embargo (original) (raw)
Latif, Anne-Louise and Holyoake, Tessa(2016) Lifting the differentiation embargo.Cell, 167(1), pp. 45-46. (doi: 10.1016/j.cell.2016.08.051) (PMID:27662083)
Abstract
Effective differentiation therapy for acute myeloid leukemia (AML) has been restricted to a small subset of patients with one defined genetic abnormality. Using an unbiased small molecule screen, Sykes et al. now identify a mechanism of de-repression of differentiation in several models of AML driven by distinct genetic drivers.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Holyoake, Professor Tessa and Latif, Dr Anne-Louise |
| Authors: | Latif, A.-L., and Holyoake, T. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Cell |
| Publisher: | Elsevier (Cell Press) |
| ISSN: | 0092-8674 |
| ISSN (Online): | 1097-4172 |
| Published Online: | 22 September 2016 |
| Copyright Holders: | Copyright © 2016 Elsevier (Cell Press) |
| First Published: | First published in Cell 167(1):45-46 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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