Cardiovascular magnetic resonance in acute ST-segment-elevation myocardial infarction: recent advances, controversies, and future directions (original) (raw)
Bulluck, Heerajnarain, Dharmakumar, Rohan, Arai, Andrew E., Berry, Colin 
ORCID: https://orcid.org/0000-0002-4547-8636 and Hausenloy, Derek J.(2018) Cardiovascular magnetic resonance in acute ST-segment-elevation myocardial infarction: recent advances, controversies, and future directions.Circulation, 137(18), pp. 1949-1964. (doi: 10.1161/CIRCULATIONAHA.117.030693) (PMID:29712696) (PMCID:PMC5933067)
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Abstract
Although mortality after ST-segment elevation myocardial infarction (MI) is on the decline, the number of patients developing heart failure as a result of MI is on the rise. Apart from timely reperfusion by primary percutaneous coronary intervention, there is currently no established therapy for reducing MI size. Thus, new cardioprotective therapies are required to improve clinical outcomes after ST-segment-elevation MI. Cardiovascular magnetic resonance has emerged as an important imaging modality for assessing the efficacy of novel therapies for reducing MI size and preventing subsequent adverse left ventricular remodeling. The recent availability of multiparametric mapping cardiovascular magnetic resonance imaging has provided new insights into the pathophysiology underlying myocardial edema, microvascular obstruction, intramyocardial hemorrhage, and changes in the remote myocardial interstitial space after ST-segment-elevation MI. In this article, we provide an overview of the recent advances in cardiovascular magnetic resonance imaging in reperfused patients with ST-segment-elevation MI, discuss the controversies surrounding its use, and explore future applications of cardiovascular magnetic resonance in this setting.
| Item Type: | Articles |
|---|---|
| Keywords: | ST elevation myocardial infarction, hemorrhage, magnetic resonance imaging, percutaneous coronary intervention. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Berry, Professor Colin |
| Authors: | Bulluck, H., Dharmakumar, R., Arai, A. E., Berry, C., and Hausenloy, D. J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | Circulation |
| Publisher: | American Heart Association |
| ISSN: | 0009-7322 |
| ISSN (Online): | 1524-4539 |
| Published Online: | 30 April 2018 |
| Copyright Holders: | Copyright © 2018 American Heart Association, Inc. |
| First Published: | First published in Circulation 137(18):1949-1964 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
University Staff: Request a correction | Enlighten Editors: Update this record
Funder and Project Information
1
BHF centre of excellence
Rhian Touyz
RE/13/5/30177
RI CARDIOVASCULAR & MEDICAL SCIENCES
1
Myocardial strain measurements in survivors of acute ST-elevation myocardial infarction: implementation and prognostic significance of novel magnetic resonance imaging methods.
Colin Berry
FS/15/54/31639
RI CARDIOVASCULAR & MEDICAL SCIENCES
1
Validation and significance of myocardial haemorrhage revealed by "bright blood" T2-weighted MRI in heart attack survivors: a prospective cohort study.
Colin Berry
PG/11/2/28474
RI CARDIOVASCULAR & MEDICAL SCIENCES
1
"First steps towards modelling myocardial infarction (a computed MI Physiome): A case-control study of novel biomechanical parameters in acute MI survivors with left ventricular dysfunction."
Colin Berry
PG/14/64/31043
RI CARDIOVASCULAR & MEDICAL SCIENCES
Deposit and Record Details
| ID Code: | 162188 |
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| Depositing User: | Publications Router |
| Datestamp: | 14 May 2018 08:54 |
| Last Modified: | 07 Sep 2020 15:13 |
| Date of first online publication: | 30 April 2018 |
| Date Deposited: | 7 June 2018 |
| Data Availability Statement: | No |