Site-specific N-alkylation of peptides on the solid phase (original) (raw)
Reichwein, J.F. and Liskamp, R.M.J. 
ORCID: https://orcid.org/0000-0001-8897-8975(1998) Site-specific N-alkylation of peptides on the solid phase.Tetrahedron Letters, 39(10), pp. 1243-1246. (doi: 10.1016/S0040-4039(97)10766-3)
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Abstract
A convenient approach, featuring a Mitsunobu reaction, is described for the introduction of an alkyl group at a specific amide function of a peptide on the solid phase. This ‘site-specific alkylation’ procedure is illustrated with an N-ethyl scan of Leu-enkephalin.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Liskamp, Professor Robert |
| Authors: | Reichwein, J.F., and Liskamp, R.M.J. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | Tetrahedron Letters |
| ISSN: | 0040-4039 |
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Deposit and Record Details
| ID Code: | 79729 |
|---|---|
| Depositing User: | Mr Toby Hanning |
| Datestamp: | 19 Aug 2013 08:52 |
| Last Modified: | 23 Sep 2021 09:03 |
| Date of first online publication: | 5 March 1998 |