Statistical issues in economic evaluations (original) (raw)

Briggs, Andrew ORCID: https://orcid.org/0000-0002-0777-1997(2014) Statistical issues in economic evaluations. In: Culyer, Anthony J. (ed.)Encyclopedia of Health Economics. Elsevier, pp. 352-361. ISBN 9780123756787(doi: 10.1016/B978-0-12-375678-7.01418-8)

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Publisher's URL: http://dx.doi.org/10.1016/B978-0-12-375678-7.01418-8

Abstract

The past two decades have seen an increasing use of statistical methods to support economic evaluation. This article give an historical overview to the development of those methods including the use of existing statistical techniques to handle the problems of skewness, censoring, and other forms of missingness in cost data, through to the problems of estimating confidence intervals for incremental cost-effectiveness (CE) ratios and the development of the net-benefit statistics with more favorable statistical properties. Finally, the increasing use of statistical methods to support and provide parameter inputs to economic evaluation models is highlighted, with particular regard to estimating heterogeneity in CE.

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