Assembling evidence for identifying reservoirs of infection (original) (raw)

Viana, Mafalda ORCID: https://orcid.org/0000-0001-5975-6505, Mancy, Rebecca ORCID: https://orcid.org/0000-0002-4667-9229, Biek, Roman ORCID: https://orcid.org/0000-0003-3471-5357, Cleaveland, Sarah ORCID: https://orcid.org/0000-0002-0456-0959, Cross, Paul C., Lloyd-Smith, James O. and Haydon, Daniel T. ORCID: https://orcid.org/0000-0002-1240-1886(2014) Assembling evidence for identifying reservoirs of infection.Trends in Ecology and Evolution, 29(5), pp. 270-279. (doi: 10.1016/j.tree.2014.03.002) (PMID:24726345) (PMCID:PMC4007595)

Abstract

Many pathogens persist in multihost systems, making the identification of infection reservoirs crucial for devising effective interventions. Here, we present a conceptual framework for classifying patterns of incidence and prevalence, and review recent scientific advances that allow us to study and manage reservoirs simultaneously. We argue that interventions can have a crucial role in enriching our mechanistic understanding of how reservoirs function and should be embedded as quasi-experimental studies in adaptive management frameworks. Single approaches to the study of reservoirs are unlikely to generate conclusive insights whereas the formal integration of data and methodologies, involving interventions, pathogen genetics, and contemporary surveillance techniques, promises to open up new opportunities to advance understanding of complex multihost systems.

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Funder and Project Information

1

Towards the strategic control of foot-and-mouth disease in Africa: new techniques for a neglected problem

Sarah Cleaveland

BB/H009302/1

RI BIODIVERSITY ANIMAL HEALTH & COMPMED

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Sarah Cleaveland

BB/J010367/1

RI BIODIVERSITY ANIMAL HEALTH & COMPMED

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