Laurent Mourot | Université de Franche-Comté (original) (raw)
Papers by Laurent Mourot
European Journal of Sport Science, Sep 17, 2014
International Journal of Sports Medicine, Oct 28, 2015
Sports Biomechanics, Apr 16, 2023
Frontiers in rehabilitation sciences, May 31, 2022
European Journal of Applied Physiology, May 23, 2018
International Journal of Psychophysiology, Sep 1, 2019
HAL (Le Centre pour la Communication Scientifique Directe), 2006
International audienc
HAL (Le Centre pour la Communication Scientifique Directe), 2019
International audienc
Scientific Reports, Apr 15, 2022
Revue Des Maladies Respiratoires, 2016
Annals of the Rheumatic Diseases, Jun 1, 2013
Background Inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and ankylosing spond... more Background Inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are associated with osteoporosis. Bone mass in RA and AS has been well evaluated by measuring areal bone mineral density (BMD) with DXA. Trabecular bone score (TBS) is a new method evaluating bone microarchitecture by assessing pixel gray- level variations in DXA images from lumbar spine. Objectives In a case-control study, TBS was evaluated in patients with RA or AS and healthy controls (HC) and the results were compared to lumbar spine (LS) BMD measurements. Changes in LS and hip BMD and TBS score after initiating and during long term anti-TNFa treatment were also examined in a prospective study. Methods In the case control study, 30 patients with RA (ACR criteria, 19 F; 12 post menopausal women; age [mean ± SD]: 56.9 ± 9.7 yrs; disease duration: 11.7 ± 8.8 yrs; 26 under low dosage corticosteroids [CTC]) and 30 patients with AS (modified NY criteria, 27 M, age 43.8 ± 13.4 yrs; disease duration: 13.0 ± 11.1 yrs; no CTC) were evaluated and compared to 50 HC (29 F, 12 post menopausal women, age: 46.6 ± 11.1 yrs). L2-L4 BMD and hip BMD were measured using DXA (Lunar GE iDXA). TBS was calculated from L2-L4 BMD images (TBS insight®, Med-Imaps). In the prospective study, a group of 20 patients requiring TNFa blocking agent (6 F; 12 AS, [age: 40.7 ± 16.1 yrs] and 8 RA [age 60.5 ± 9.7 yrs]; disease duration: 9.6 ± 9.8 yrs; 9 under low dose CTC) were followed for 2 years. LS BMD, hip BMD and TBS score were measured at baseline and after 6, 12 and 24 months of treatment. Results - Case control study: RA patients had lower BMD and T score at the hip (p < 0.005) compared to HC. Hip T score in patients with AS was also decreased (p = 0.02). LS BMD did not differ between patients and HC. TBS was lower in RA and AS compared to HC: 1.242 ± 0.16 and 1.282 ± 0.13 vs 1.365 ± 0.14, respectively (p= 0.005). - Prospective study: under anti-TNFa, LS and hip BMD at M24 increased (+ 6.3% and + 2.4% respectively), with significant changes at the spine (p< 0.001). In the whole group, TBS score slightly increased from baseline to M12 (1,304 ± 0.13 to 1.32 ± 0.09) without significance, then returning to initial values at M24 (1.309 ± 0.09). However, in patients with RA, TBS score decreased (baseline to M24: 1.362 ± 0.048 to 1.308 ± 0.07) (p = 0.032) while in patients with AS, TBS progressively increased (1.257 ± 0.15 vs 1.309 ± 0.11; NS). Conclusions TBS score is decreased in inflammatory rheumatic diseases, especially in RA, suggesting alterations of bone micro architecture. Long term anti TNFa treatment is associated with a positive effect on (LS) bone mass but no major changes in TBS score. Surprisingly and on the contrary of AS, TBS score decreased in RA treated by TNFa blocking agents, suggesting different influences and responses of the bone to this drug’s class. Disclosure of Interest None Declared
International Journal of Environmental Research and Public Health, Sep 26, 2022
HAL (Le Centre pour la Communication Scientifique Directe), Apr 1, 2015
This study aimed to compare the kinetics of muscle leg blood flow during three recovery treatment... more This study aimed to compare the kinetics of muscle leg blood flow during three recovery treatments following a prolonged exercise: contrast water therapy (CWT), compression stockings (CS) or passive recovery (PR). Fifteen men came to the laboratory three times to perform a 45--min exercise followed 5 min after by a standardized 12--min recovery treatment in upright position, alternating between two vats every 2 min: CWT (cold: ~12°C to warm: 36°C), CS (~20 mmHg) or PR. The order of treatments was randomized. Blood flow was measured using Doppler ultrasound during the recovery treatments (i.e. min 3, 5, 7 and 9) in the superficial femoral artery distally to the common bifurcation (~3 cm) (above the water and stocking). Blood flow was significantly higher during CWT (p < 0.01;; +22.91%) and CS (p < 0.05; +15.26%) than during PR. Although no statistical difference between CWT and CS was observed, effect sizes were larger during CWT (large) than during CS (moderate). No changes in blood flow occurred in the femoral artery between hot and cold transitions of CWT. During immediate recovery of a high intensity exercise, CWT and CS trigger higher femoral artery blood flow than PR. Moreover, effect sizes were greater during CWT than during CS.
Scandinavian Journal of Medicine & Science in Sports, May 16, 2018
This study examined the trajectories of elite swimmers’ recovery‐stress states and cardiac vagal‐... more This study examined the trajectories of elite swimmers’ recovery‐stress states and cardiac vagal‐related markers during a 3‐month training period preceding the national championship and their within‐person relationships with perceived control. A Multilevel Growth Curve Analysis (MGCA) approach was used with 21 male elite swimmers. Four waves of assessments of psychological (stress, recovery, perceived control) and physiological (heart rate recovery, heart rate variability) markers were completed during a 3month training preparation leading to a major competition. Results of MGCA revealed (a) a significant positive linear effect of time (ie, linear increase over time) and a significant negative quadratic effect of time (ie, inverted U shape over time) on perceived stress whereas the opposite pattern of results was observed for perceived recovery; and (b) a significant positive linear effect of time for nHRR60. Both at level 1 (within‐person level of analysis) and 2 (between‐person level of analysis), perceived control was (a) positively associated with athletes’ perceived recovery and parasympathetic markers (ie, MeanRR; pNN50); and (b) negatively related to swimmers’ perceived stress. Results also indicated that within‐person interactions of perceived control with time reached significance for general recovery and HRV. Finally, within‐person interaction of perceived control with squared time reached significance for subjective sport‐specific and total stress. Overall, this study provided insights into the key role played by perceived control on both psychological and physiological markers related to recovery‐stress states’ levels during the 3‐month training period preceding the national championship.
European journal of nutrition, Oct 31, 2013
To evaluate the long-term consequences of TNFα inhibitors on body composition and fat distributio... more To evaluate the long-term consequences of TNFα inhibitors on body composition and fat distribution, as well as changes in serum adipokines in patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS). Eight patients with RA and twelve with AS requiring a TNFα inhibitor were prospectively followed for 2 years. Body composition was evaluated by dual X-ray absorptiometry and included measurements of total fat mass, lean mass, fat in the gynoid and android regions, and visceral fat. Serum leptin, total and high molecular weight (HMW) adiponectin, resistin, and ghrelin were also assessed. There was a significant gain in body mass index (p = 0.05) and a tendency for weight (p = 0.07), android fat (p = 0.07), and visceral fat (p = 0.059) increase in patients with RA, while in AS, total fat mass significantly increased (p = 0.02) with a parallel weight gain (p = 0.07). When examining the whole population of patients, we observed after 2 years a significant increase in body weight (+1.9%; p = 0.003), body mass index (+2.5%; p = 0.004), total fat mass (+11.1%; p = 0.007), and fat in the android region (+18.3%; p = 0.02). There was a substantial, albeit nonsignificant gain in visceral fat (+24.3%; p = 0.088). Lean mass and gynoid fat were not modified. No major changes were observed for serum leptin, total adiponectin, and ghrelin, while HMW adiponectin and the HMW/total adiponectin ratio tended to decrease (-15.2%, p = 0.057 and -9.3%, p = 0.067, respectively). Resistin decreased significantly (-22.4%, p = 0.01). Long-term TNFα inhibition in RA and AS is associated with a significant gain in fat mass, with a shift to the android (visceral) region. This fat redistribution raises questions about its influence on the cardiovascular profile of patients receiving these treatments.
Scandinavian Journal of Medicine & Science in Sports, Feb 26, 2013
Journal of Athletic Enhancement, 2019
Running form being a global system defined by several biomechanical parameters, it is of major in... more Running form being a global system defined by several biomechanical parameters, it is of major interest to assess it using a global method. For this purpose, the Volodalen® scale was developed. This scale, based on five items, attributes a global subjective score (V®score) to the running form of individuals and allows their classification along an aerial-terrestrial continuum. As no study has yet reported the reliability of such scale, the aim of this paper was to evaluate its intra- and inter-rater reliability. Thirty-six runners ran two 10-min running trials. Runners were classified according to their V®score by two experts and one novice raters. Relative and absolute reliability, and systematic bias were determined by intra-class correlation coefficient (ICC), coefficient of variation (CV), and statistically significant difference, respectively. Regarding the global V®score, high intra-rater reliability for the expert (CV=6.1 ± 7.0%, ICC=0.940, and p-value=0.864) and high inter-r...
Journal of Science and Cycling, 2013
Many researchers have investigated the effectiveness of contrast water therapy (CWT) or compressi... more Many researchers have investigated the effectiveness of contrast water therapy (CWT) or compression stockings (CS) during recovery, using subsequent performance as the principal outcome measure. However, data in the literature are contradictory, mainly because of the methodology used. Purpose: Based on well-controlled performance measures, this study aimed to compare the effects of CWT, CS or passive recovery (PR) on subsequent performance. Methods: After inclusion based on reproducibility criteria (intra-participant variability in performance test lower than the expected differences between the recovery interventions, i.e. 1.5%), 12 competitive male cyclists (peak power output: 5.0 ± 0.2 W/kg; cycling practice: 4.9 ± 0.4 times/week; intra-participant variability: 1.2 ± 0.2%) came to the laboratory three times in a random crossover design. Each time visit, they performed a tiring exercise on a cycle ergometer, followed by a 5-min performance test during which the mean power outpu...
European Journal of Sport Science, 2021
European Journal of Applied Physiology, Oct 20, 2022
European Journal of Sport Science, Sep 17, 2014
International Journal of Sports Medicine, Oct 28, 2015
Sports Biomechanics, Apr 16, 2023
Frontiers in rehabilitation sciences, May 31, 2022
European Journal of Applied Physiology, May 23, 2018
International Journal of Psychophysiology, Sep 1, 2019
HAL (Le Centre pour la Communication Scientifique Directe), 2006
International audienc
HAL (Le Centre pour la Communication Scientifique Directe), 2019
International audienc
Scientific Reports, Apr 15, 2022
Revue Des Maladies Respiratoires, 2016
Annals of the Rheumatic Diseases, Jun 1, 2013
Background Inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and ankylosing spond... more Background Inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are associated with osteoporosis. Bone mass in RA and AS has been well evaluated by measuring areal bone mineral density (BMD) with DXA. Trabecular bone score (TBS) is a new method evaluating bone microarchitecture by assessing pixel gray- level variations in DXA images from lumbar spine. Objectives In a case-control study, TBS was evaluated in patients with RA or AS and healthy controls (HC) and the results were compared to lumbar spine (LS) BMD measurements. Changes in LS and hip BMD and TBS score after initiating and during long term anti-TNFa treatment were also examined in a prospective study. Methods In the case control study, 30 patients with RA (ACR criteria, 19 F; 12 post menopausal women; age [mean ± SD]: 56.9 ± 9.7 yrs; disease duration: 11.7 ± 8.8 yrs; 26 under low dosage corticosteroids [CTC]) and 30 patients with AS (modified NY criteria, 27 M, age 43.8 ± 13.4 yrs; disease duration: 13.0 ± 11.1 yrs; no CTC) were evaluated and compared to 50 HC (29 F, 12 post menopausal women, age: 46.6 ± 11.1 yrs). L2-L4 BMD and hip BMD were measured using DXA (Lunar GE iDXA). TBS was calculated from L2-L4 BMD images (TBS insight®, Med-Imaps). In the prospective study, a group of 20 patients requiring TNFa blocking agent (6 F; 12 AS, [age: 40.7 ± 16.1 yrs] and 8 RA [age 60.5 ± 9.7 yrs]; disease duration: 9.6 ± 9.8 yrs; 9 under low dose CTC) were followed for 2 years. LS BMD, hip BMD and TBS score were measured at baseline and after 6, 12 and 24 months of treatment. Results - Case control study: RA patients had lower BMD and T score at the hip (p < 0.005) compared to HC. Hip T score in patients with AS was also decreased (p = 0.02). LS BMD did not differ between patients and HC. TBS was lower in RA and AS compared to HC: 1.242 ± 0.16 and 1.282 ± 0.13 vs 1.365 ± 0.14, respectively (p= 0.005). - Prospective study: under anti-TNFa, LS and hip BMD at M24 increased (+ 6.3% and + 2.4% respectively), with significant changes at the spine (p< 0.001). In the whole group, TBS score slightly increased from baseline to M12 (1,304 ± 0.13 to 1.32 ± 0.09) without significance, then returning to initial values at M24 (1.309 ± 0.09). However, in patients with RA, TBS score decreased (baseline to M24: 1.362 ± 0.048 to 1.308 ± 0.07) (p = 0.032) while in patients with AS, TBS progressively increased (1.257 ± 0.15 vs 1.309 ± 0.11; NS). Conclusions TBS score is decreased in inflammatory rheumatic diseases, especially in RA, suggesting alterations of bone micro architecture. Long term anti TNFa treatment is associated with a positive effect on (LS) bone mass but no major changes in TBS score. Surprisingly and on the contrary of AS, TBS score decreased in RA treated by TNFa blocking agents, suggesting different influences and responses of the bone to this drug’s class. Disclosure of Interest None Declared
International Journal of Environmental Research and Public Health, Sep 26, 2022
HAL (Le Centre pour la Communication Scientifique Directe), Apr 1, 2015
This study aimed to compare the kinetics of muscle leg blood flow during three recovery treatment... more This study aimed to compare the kinetics of muscle leg blood flow during three recovery treatments following a prolonged exercise: contrast water therapy (CWT), compression stockings (CS) or passive recovery (PR). Fifteen men came to the laboratory three times to perform a 45--min exercise followed 5 min after by a standardized 12--min recovery treatment in upright position, alternating between two vats every 2 min: CWT (cold: ~12°C to warm: 36°C), CS (~20 mmHg) or PR. The order of treatments was randomized. Blood flow was measured using Doppler ultrasound during the recovery treatments (i.e. min 3, 5, 7 and 9) in the superficial femoral artery distally to the common bifurcation (~3 cm) (above the water and stocking). Blood flow was significantly higher during CWT (p < 0.01;; +22.91%) and CS (p < 0.05; +15.26%) than during PR. Although no statistical difference between CWT and CS was observed, effect sizes were larger during CWT (large) than during CS (moderate). No changes in blood flow occurred in the femoral artery between hot and cold transitions of CWT. During immediate recovery of a high intensity exercise, CWT and CS trigger higher femoral artery blood flow than PR. Moreover, effect sizes were greater during CWT than during CS.
Scandinavian Journal of Medicine & Science in Sports, May 16, 2018
This study examined the trajectories of elite swimmers’ recovery‐stress states and cardiac vagal‐... more This study examined the trajectories of elite swimmers’ recovery‐stress states and cardiac vagal‐related markers during a 3‐month training period preceding the national championship and their within‐person relationships with perceived control. A Multilevel Growth Curve Analysis (MGCA) approach was used with 21 male elite swimmers. Four waves of assessments of psychological (stress, recovery, perceived control) and physiological (heart rate recovery, heart rate variability) markers were completed during a 3month training preparation leading to a major competition. Results of MGCA revealed (a) a significant positive linear effect of time (ie, linear increase over time) and a significant negative quadratic effect of time (ie, inverted U shape over time) on perceived stress whereas the opposite pattern of results was observed for perceived recovery; and (b) a significant positive linear effect of time for nHRR60. Both at level 1 (within‐person level of analysis) and 2 (between‐person level of analysis), perceived control was (a) positively associated with athletes’ perceived recovery and parasympathetic markers (ie, MeanRR; pNN50); and (b) negatively related to swimmers’ perceived stress. Results also indicated that within‐person interactions of perceived control with time reached significance for general recovery and HRV. Finally, within‐person interaction of perceived control with squared time reached significance for subjective sport‐specific and total stress. Overall, this study provided insights into the key role played by perceived control on both psychological and physiological markers related to recovery‐stress states’ levels during the 3‐month training period preceding the national championship.
European journal of nutrition, Oct 31, 2013
To evaluate the long-term consequences of TNFα inhibitors on body composition and fat distributio... more To evaluate the long-term consequences of TNFα inhibitors on body composition and fat distribution, as well as changes in serum adipokines in patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS). Eight patients with RA and twelve with AS requiring a TNFα inhibitor were prospectively followed for 2 years. Body composition was evaluated by dual X-ray absorptiometry and included measurements of total fat mass, lean mass, fat in the gynoid and android regions, and visceral fat. Serum leptin, total and high molecular weight (HMW) adiponectin, resistin, and ghrelin were also assessed. There was a significant gain in body mass index (p = 0.05) and a tendency for weight (p = 0.07), android fat (p = 0.07), and visceral fat (p = 0.059) increase in patients with RA, while in AS, total fat mass significantly increased (p = 0.02) with a parallel weight gain (p = 0.07). When examining the whole population of patients, we observed after 2 years a significant increase in body weight (+1.9%; p = 0.003), body mass index (+2.5%; p = 0.004), total fat mass (+11.1%; p = 0.007), and fat in the android region (+18.3%; p = 0.02). There was a substantial, albeit nonsignificant gain in visceral fat (+24.3%; p = 0.088). Lean mass and gynoid fat were not modified. No major changes were observed for serum leptin, total adiponectin, and ghrelin, while HMW adiponectin and the HMW/total adiponectin ratio tended to decrease (-15.2%, p = 0.057 and -9.3%, p = 0.067, respectively). Resistin decreased significantly (-22.4%, p = 0.01). Long-term TNFα inhibition in RA and AS is associated with a significant gain in fat mass, with a shift to the android (visceral) region. This fat redistribution raises questions about its influence on the cardiovascular profile of patients receiving these treatments.
Scandinavian Journal of Medicine & Science in Sports, Feb 26, 2013
Journal of Athletic Enhancement, 2019
Running form being a global system defined by several biomechanical parameters, it is of major in... more Running form being a global system defined by several biomechanical parameters, it is of major interest to assess it using a global method. For this purpose, the Volodalen® scale was developed. This scale, based on five items, attributes a global subjective score (V®score) to the running form of individuals and allows their classification along an aerial-terrestrial continuum. As no study has yet reported the reliability of such scale, the aim of this paper was to evaluate its intra- and inter-rater reliability. Thirty-six runners ran two 10-min running trials. Runners were classified according to their V®score by two experts and one novice raters. Relative and absolute reliability, and systematic bias were determined by intra-class correlation coefficient (ICC), coefficient of variation (CV), and statistically significant difference, respectively. Regarding the global V®score, high intra-rater reliability for the expert (CV=6.1 ± 7.0%, ICC=0.940, and p-value=0.864) and high inter-r...
Journal of Science and Cycling, 2013
Many researchers have investigated the effectiveness of contrast water therapy (CWT) or compressi... more Many researchers have investigated the effectiveness of contrast water therapy (CWT) or compression stockings (CS) during recovery, using subsequent performance as the principal outcome measure. However, data in the literature are contradictory, mainly because of the methodology used. Purpose: Based on well-controlled performance measures, this study aimed to compare the effects of CWT, CS or passive recovery (PR) on subsequent performance. Methods: After inclusion based on reproducibility criteria (intra-participant variability in performance test lower than the expected differences between the recovery interventions, i.e. 1.5%), 12 competitive male cyclists (peak power output: 5.0 ± 0.2 W/kg; cycling practice: 4.9 ± 0.4 times/week; intra-participant variability: 1.2 ± 0.2%) came to the laboratory three times in a random crossover design. Each time visit, they performed a tiring exercise on a cycle ergometer, followed by a 5-min performance test during which the mean power outpu...
European Journal of Sport Science, 2021
European Journal of Applied Physiology, Oct 20, 2022