P. Campioni | Università degli Studi di Ferrara (original) (raw)
Papers by P. Campioni
The aim of this study was to assess the role of pelvic MRI in the evaluation of late (>12 mont... more The aim of this study was to assess the role of pelvic MRI in the evaluation of late (>12 months) bladder toxicity of pelvic radiotherapy (RT) and brachytherapy (BRT) in patients with endometrial cancer. These patients underwent hysterectomy followed by RT and BRT on the vaginal fund. All patients were disease-free. It is known that toxic effects are those that appear late or persist after six to twelve months from the end of radiation treatment. It is also known that radiation therapy may induce local tissue damage that in turn, depending on the severity and the volume affected, may lead to organ dysfunction. We used pelvic MRI performed with 1.5 T scanner (GE Signa) to evaluate bladder floor morphology, and then we compared these achievements with clinical manifestations. The clinical symptoms were classified using the LENT SOMA score (late effect of normal tissues - subjective objective management and analysis) developed by RTOG (Radiotherapy Oncology Group)
European Radiology, 2012
Objective To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced ma... more Objective To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced magnetic resonance imaging (MRI) to a control group (unenhanced MRI) in high-risk patients. Methods Patients with chronic kidney disease (CKD) scheduled for MRI procedures were screened. The primary endpoint was the percentage of patients with an elevation of serum creatinine levels, measured 72±24 h after the MRI procedure, by at least 25 % or 44.2 μmol/l (0.5 mg/dl) from baseline. A non-inferiority margin of the between-group difference was set at −15 % for statistical analysis of the primary endpoint. Main secondary endpoints were the variation in serum creatinine and eGFR values between baseline and 72±24 h after MRI and the percentage of patients with a decrease in eGFR of at least 25 % from baseline. Patients were screened for signs of nephrogenic systemic fibrosis (NSF) at 3-month follow-up.
The Journal of nuclear medicine and allied sciences, 1989
Otorhinolaryngology, 2018
The aim of this paper was to describe a patient affected by isolated abducens nerve palsy and vis... more The aim of this paper was to describe a patient affected by isolated abducens nerve palsy and visual disturbances due to a bilateral acute paranasal sinus infection. Patient medical records and imaging studies were reviewed, as well as the literature on the topic. Our patient presented an upper respiratory tract infection, associated with fever, severe progressively worsening headache and diplopia. Physical examination demonstrated right-sided sixth cranial nerve palsy. Imaging studies were consistent with bilateral pan-sinusal inflammatory disease. The patient was initially treated with antibiotics and betamethasone; upon 48 hours, due to the persistence of symptoms, she underwent sinuses drainage by functional endoscopic sinus surgery. After the complete resolution of the infection, at the control MRI study a Dorello's canal was demonstrated on the right side. Cranial nerve palsies associated to paranasal sinus infection have already been reported; however in this case we evidenced a direct correlation between the sinusal (sphenoidal) involvement and the abducens nerve
Rays
A case of diabetic foot in a patient with advanced diabetes is presented. The correct diagnostic ... more A case of diabetic foot in a patient with advanced diabetes is presented. The correct diagnostic approach was analyzed based on the reasoned combination of available diagnostic imaging procedures (color-Doppler US, CT-angiography, MR-angiography and digital subtraction angiography) and on the clinician's instances. Angiographic findings contraindicated intravascular treatment. Femorotibial surgical bypass was performed.
Rays
The case of a patient with dysphonia and ingravescent dysphagia, associated with crises of lipoth... more The case of a patient with dysphonia and ingravescent dysphagia, associated with crises of lipothymia "ab ingestis" is discussed. ENT examination with videolaryngoscopy evidenced a swelling of the posterior hypopharyngeal wall. X-ray study of the upper digestive tract was discontinued for inhalation. The scintigraphic study of swalling documented marked alteration of the oropharyngeal phase with phenomena of post-deglutitory aspiration. CT of the cervical vertebral column documented anterior diffuse vertebral hyperostosis of C3-C6: this finding was suggestive of Forestier disease.
Journal of Clinical Ultrasound, 2001
Purpose. The purpose of this study was to compare contrast-enhanced gray-scale voiding urosonogra... more Purpose. The purpose of this study was to compare contrast-enhanced gray-scale voiding urosonography (CE-VUS) and contrast-enhanced color Doppler voiding urosonography (CE-CDVUS) with voiding cystourethrography (VCUG) to verify whether the use of color Doppler imaging improves the diagnosis and grading of vesicoureteral reflux (VUR). Methods. In 74 patients, CE-VUS and CE-CDVUS were compared with VCUG, which was used as the gold standard. SHU 508 A (Levovist) was used as the echo-enhancing contrast agent. VUR was diagnosed if hyperechoic dots or color signals were visualized in the ureter on sonograms. VUR grading was based on morphologic and dynamic findings on CE-VUS and morphologic and color findings on CE-CDVUS. VCUG was performed conventionally, and grading by VCUG was in accordance with the international system of radiographic VUR grading. Patients who voided during 1 examination only (either CE-VUS and CE-CDVUS or VCUG) were excluded from the study. Agreement between the results of CE-VUS and VCUG and between those of CE-CDVUS and VCUG in diagnosing VUR was calculated by statistics. CE-VUS and CE-CDVUS were compared for diagnostic accuracy by the McNemar test. Results. The agreement between CE-VUS and VCUG in predicting VUR was 90% (score, 0.77; p < 0.001). The agreement between CE-CDVUS and VCUG was 96% (score, 0.91; p < 0.001). CE-CDVUS showed a significantly higher diagnostic accuracy than did CE-VUS (96% versus 90% of cases correctly classified; McNemar 2 = 4; p < 0.05). This was mainly related to the lower number of false-negative results for grade I and grade II VUR when CE-CDVUS was used. Conclusions. The use of color Doppler imaging significantly improves the accuracy of contrast voiding urosonography in the detection and grading of VUR.
Rays, 1998
One of the major and demanding problems in the management of a modern department of Radiology is ... more One of the major and demanding problems in the management of a modern department of Radiology is undoubtedly the organization of a radiologic archive. Its management has been increasingly difficult in last years both for the increase in procedures and the number of radiologic exams. At the Radiology department of UCSC, since some years, this problem has been tackled. Major objectives have been identified in focusing on responsibilities, global management and planning of radiologic film retrieval and archiving integrated with health care activities (scheduling of admissions and exam appointments, reporting, discharge). Based on these assumptions, the archive has been divided into 3 sections, each dynamically integrated with the others. The 3 archives should be integrated with RIS and supported by information technology. RIS is considered the starting point of the process. In fact the system ensures communication to the archiving workstation and to the radiology room of patient admiss...
Rays, 1998
Cervical incompetence is defined as an abnormal dilatation of the cervical canal at the body-neck... more Cervical incompetence is defined as an abnormal dilatation of the cervical canal at the body-neck junction with no pain or blood loss and in the absence of uterine contractile activity. Cervical incompetence is the frequent cause of abortion in the second trimester and premature delivery, with adverse fetal prognosis. Usually, three causative factors are considered: traumatic, constitutional, dysfunctional. While in multiparous women the medical and remote obstetric history poses the diagnostic suspicion, in primigravidae, in the absence of previous risk factors (traumas, malformations, etc) early diagnosis may allow prompt treatment with a better prognosis. Hysterosalpingographic (tunnel-shaped cervix or appearing as an inverted sac, diameter of internal uterine orifice) but especially sonographic findings (cervical length, dilated endocervical canal, tunnel-shaped internal uterine orifice, herniation of the amniotic sac into the endocervical canal) represent the most significant r...
Rays, 1996
From the clinical standpoint, the report represents the synthesis of the diagnostic process and i... more From the clinical standpoint, the report represents the synthesis of the diagnostic process and it is the central activity of radiology. However, reporting cannot be separated from the entire organizational cycle inside the Diagnostic Imaging Department as well as within the structure as a whole. The effectiveness of the contribution an information system can give to the radiologist is related to the information and functional integration of the various applications operating in the hospital and over the territory. Based on these considerations, the main types of support the information tool can offer, are reported together with the primary objectives which were basic to the development of the reporting module within the DREAM system and the major solutions adopted to facilitate the attainment of these objectives.
The aim of this study was to assess the role of pelvic MRI in the evaluation of late (>12 mont... more The aim of this study was to assess the role of pelvic MRI in the evaluation of late (>12 months) bladder toxicity of pelvic radiotherapy (RT) and brachytherapy (BRT) in patients with endometrial cancer. These patients underwent hysterectomy followed by RT and BRT on the vaginal fund. All patients were disease-free. It is known that toxic effects are those that appear late or persist after six to twelve months from the end of radiation treatment. It is also known that radiation therapy may induce local tissue damage that in turn, depending on the severity and the volume affected, may lead to organ dysfunction. We used pelvic MRI performed with 1.5 T scanner (GE Signa) to evaluate bladder floor morphology, and then we compared these achievements with clinical manifestations. The clinical symptoms were classified using the LENT SOMA score (late effect of normal tissues - subjective objective management and analysis) developed by RTOG (Radiotherapy Oncology Group)
European Radiology, 2012
Objective To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced ma... more Objective To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced magnetic resonance imaging (MRI) to a control group (unenhanced MRI) in high-risk patients. Methods Patients with chronic kidney disease (CKD) scheduled for MRI procedures were screened. The primary endpoint was the percentage of patients with an elevation of serum creatinine levels, measured 72±24 h after the MRI procedure, by at least 25 % or 44.2 μmol/l (0.5 mg/dl) from baseline. A non-inferiority margin of the between-group difference was set at −15 % for statistical analysis of the primary endpoint. Main secondary endpoints were the variation in serum creatinine and eGFR values between baseline and 72±24 h after MRI and the percentage of patients with a decrease in eGFR of at least 25 % from baseline. Patients were screened for signs of nephrogenic systemic fibrosis (NSF) at 3-month follow-up.
The Journal of nuclear medicine and allied sciences, 1989
Otorhinolaryngology, 2018
The aim of this paper was to describe a patient affected by isolated abducens nerve palsy and vis... more The aim of this paper was to describe a patient affected by isolated abducens nerve palsy and visual disturbances due to a bilateral acute paranasal sinus infection. Patient medical records and imaging studies were reviewed, as well as the literature on the topic. Our patient presented an upper respiratory tract infection, associated with fever, severe progressively worsening headache and diplopia. Physical examination demonstrated right-sided sixth cranial nerve palsy. Imaging studies were consistent with bilateral pan-sinusal inflammatory disease. The patient was initially treated with antibiotics and betamethasone; upon 48 hours, due to the persistence of symptoms, she underwent sinuses drainage by functional endoscopic sinus surgery. After the complete resolution of the infection, at the control MRI study a Dorello's canal was demonstrated on the right side. Cranial nerve palsies associated to paranasal sinus infection have already been reported; however in this case we evidenced a direct correlation between the sinusal (sphenoidal) involvement and the abducens nerve
Rays
A case of diabetic foot in a patient with advanced diabetes is presented. The correct diagnostic ... more A case of diabetic foot in a patient with advanced diabetes is presented. The correct diagnostic approach was analyzed based on the reasoned combination of available diagnostic imaging procedures (color-Doppler US, CT-angiography, MR-angiography and digital subtraction angiography) and on the clinician's instances. Angiographic findings contraindicated intravascular treatment. Femorotibial surgical bypass was performed.
Rays
The case of a patient with dysphonia and ingravescent dysphagia, associated with crises of lipoth... more The case of a patient with dysphonia and ingravescent dysphagia, associated with crises of lipothymia "ab ingestis" is discussed. ENT examination with videolaryngoscopy evidenced a swelling of the posterior hypopharyngeal wall. X-ray study of the upper digestive tract was discontinued for inhalation. The scintigraphic study of swalling documented marked alteration of the oropharyngeal phase with phenomena of post-deglutitory aspiration. CT of the cervical vertebral column documented anterior diffuse vertebral hyperostosis of C3-C6: this finding was suggestive of Forestier disease.
Journal of Clinical Ultrasound, 2001
Purpose. The purpose of this study was to compare contrast-enhanced gray-scale voiding urosonogra... more Purpose. The purpose of this study was to compare contrast-enhanced gray-scale voiding urosonography (CE-VUS) and contrast-enhanced color Doppler voiding urosonography (CE-CDVUS) with voiding cystourethrography (VCUG) to verify whether the use of color Doppler imaging improves the diagnosis and grading of vesicoureteral reflux (VUR). Methods. In 74 patients, CE-VUS and CE-CDVUS were compared with VCUG, which was used as the gold standard. SHU 508 A (Levovist) was used as the echo-enhancing contrast agent. VUR was diagnosed if hyperechoic dots or color signals were visualized in the ureter on sonograms. VUR grading was based on morphologic and dynamic findings on CE-VUS and morphologic and color findings on CE-CDVUS. VCUG was performed conventionally, and grading by VCUG was in accordance with the international system of radiographic VUR grading. Patients who voided during 1 examination only (either CE-VUS and CE-CDVUS or VCUG) were excluded from the study. Agreement between the results of CE-VUS and VCUG and between those of CE-CDVUS and VCUG in diagnosing VUR was calculated by statistics. CE-VUS and CE-CDVUS were compared for diagnostic accuracy by the McNemar test. Results. The agreement between CE-VUS and VCUG in predicting VUR was 90% (score, 0.77; p < 0.001). The agreement between CE-CDVUS and VCUG was 96% (score, 0.91; p < 0.001). CE-CDVUS showed a significantly higher diagnostic accuracy than did CE-VUS (96% versus 90% of cases correctly classified; McNemar 2 = 4; p < 0.05). This was mainly related to the lower number of false-negative results for grade I and grade II VUR when CE-CDVUS was used. Conclusions. The use of color Doppler imaging significantly improves the accuracy of contrast voiding urosonography in the detection and grading of VUR.
Rays, 1998
One of the major and demanding problems in the management of a modern department of Radiology is ... more One of the major and demanding problems in the management of a modern department of Radiology is undoubtedly the organization of a radiologic archive. Its management has been increasingly difficult in last years both for the increase in procedures and the number of radiologic exams. At the Radiology department of UCSC, since some years, this problem has been tackled. Major objectives have been identified in focusing on responsibilities, global management and planning of radiologic film retrieval and archiving integrated with health care activities (scheduling of admissions and exam appointments, reporting, discharge). Based on these assumptions, the archive has been divided into 3 sections, each dynamically integrated with the others. The 3 archives should be integrated with RIS and supported by information technology. RIS is considered the starting point of the process. In fact the system ensures communication to the archiving workstation and to the radiology room of patient admiss...
Rays, 1998
Cervical incompetence is defined as an abnormal dilatation of the cervical canal at the body-neck... more Cervical incompetence is defined as an abnormal dilatation of the cervical canal at the body-neck junction with no pain or blood loss and in the absence of uterine contractile activity. Cervical incompetence is the frequent cause of abortion in the second trimester and premature delivery, with adverse fetal prognosis. Usually, three causative factors are considered: traumatic, constitutional, dysfunctional. While in multiparous women the medical and remote obstetric history poses the diagnostic suspicion, in primigravidae, in the absence of previous risk factors (traumas, malformations, etc) early diagnosis may allow prompt treatment with a better prognosis. Hysterosalpingographic (tunnel-shaped cervix or appearing as an inverted sac, diameter of internal uterine orifice) but especially sonographic findings (cervical length, dilated endocervical canal, tunnel-shaped internal uterine orifice, herniation of the amniotic sac into the endocervical canal) represent the most significant r...
Rays, 1996
From the clinical standpoint, the report represents the synthesis of the diagnostic process and i... more From the clinical standpoint, the report represents the synthesis of the diagnostic process and it is the central activity of radiology. However, reporting cannot be separated from the entire organizational cycle inside the Diagnostic Imaging Department as well as within the structure as a whole. The effectiveness of the contribution an information system can give to the radiologist is related to the information and functional integration of the various applications operating in the hospital and over the territory. Based on these considerations, the main types of support the information tool can offer, are reported together with the primary objectives which were basic to the development of the reporting module within the DREAM system and the major solutions adopted to facilitate the attainment of these objectives.