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... Title: Oral Cavity and Floor of the Mouth: Benign Tumors. Authors: Hermans, Robert Mancuso,An... more ... Title: Oral Cavity and Floor of the Mouth: Benign Tumors. Authors: Hermans, Robert Mancuso,Anthony Collins, William. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1844-1850. ...
... Title: Larynx: Introduction, Normal Anatomy and Function. Authors: Hermans, Robert Mancuso,An... more ... Title: Larynx: Introduction, Normal Anatomy and Function. Authors: Hermans, Robert Mancuso,Anthony. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1893-1924. ISBN: 978-1-60547-715-2. ...
International Journal of Radiation Oncology Biology Physics, Sep 1, 1999
Purpose: To determine if pre-radiotherapy (RT) and/or post-radiotherapy computed tomography (CT) ... more Purpose: To determine if pre-radiotherapy (RT) and/or post-radiotherapy computed tomography (CT) can predict local failure in patients with laryngeal carcinoma treated with definitive RT. Methods and Materials: The pre-and post-RT CT examinations of 59 patients (T3 glottic carcinoma [n ؍ 30] and T1-T4 supraglottic carcinoma [n ؍ 29]) were reviewed. For each patient, the first post-RT CT study between 1 and 6 months after irradiation was used. All patients were treated with definitive hyperfractionated twice-daily continuous-course irradiation to a total dose of 6,720-7,920 cGy, and followed-up clinically for at least 2 years after completion of RT. Local control was defined as absence of primary tumor recurrence and a functioning larynx. On the pre-treatment CT study, each tumor was assigned a high-or low-risk profile for local failure after RT. The post-RT CT examinations were evaluated for post-treatment changes using a three-point post-RT CT-score: 1 ؍ expected post-RT changes; 2 ؍ focal mass with a maximal diameter of < 1 cm and/or asymmetric obliteration of laryngeal tissue planes; 3 ؍ focal mass with a maximal diameter of > 1 cm, or < 50% estimated tumor volume reduction. Results: The local control rates at 2 years post-RT based on pre-treatment CT evaluation were 88% for low pre-treatment risk profile patients (95% CI: 66-96%) and 34% (95% CI: 19-50%) for high pre-treatment risk profile patients (risk ratio 6.583; 95% CI: 2.265-9.129; p ؍ 0.0001). Based on post-treatment CT, the local control rates at 2 years post-RT were 94% for score 1, 67% for score 2, and 10% for score 3 (risk ratio 4.760; 95% CI: 2.278-9.950 p ؍ 0.0001). Post-RT CT scores added significant information to the pre-treatment risk profiles on prognosis. Conclusions: Pre-treatment CT risk profiles, as well as post-RT CT evaluation can identify patients, irradiated for laryngeal carcinomas, at high risk for developing local failure. When the post-RT CT score is available, it proves to be an even better prognosticator than the pre-treatment CT-risk profile.
... Title: Larynx: Infectious and Noninfectious Inflammatory Diseases. Authors: Hermans, Robert M... more ... Title: Larynx: Infectious and Noninfectious Inflammatory Diseases. Authors: Hermans, Robert Mancuso, Anthony Collins, William. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1946-1963. ...
... Title: Oral Cavity: Infectious and Noninfectious Inflammatory Conditions. Authors: Hermans, R... more ... Title: Oral Cavity: Infectious and Noninfectious Inflammatory Conditions. Authors: Hermans, Robert Mancuso, Anthony Collins, William. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1836-1845. ...
AJNR. American journal of neuroradiology, Jan 16, 2015
Acute invasive fungal rhinosinusitis carries a high mortality rate. An easy-to-use and accurate p... more Acute invasive fungal rhinosinusitis carries a high mortality rate. An easy-to-use and accurate predictive imaging model is currently lacking. We assessed the performance of various CT findings for the identification of acute invasive fungal rhinosinusitis and synthesized a simple and robust diagnostic model to serve as an easily applicable screening tool for at-risk patients. Two blinded neuroradiologists retrospectively graded 23 prespecified imaging abnormalities in the craniofacial region on craniofacial CT examinations from 42 patients with pathology-proven acute invasive fungal rhinosinusitis and 42 control patients proved negative for acute invasive fungal rhinosinusitis from the same high-risk population. A third blinded neuroradiologist decided discrepancies. Specificity, sensitivity, positive predictive value, and negative predictive value were determined for all individual variables. The 23 variables were evaluated for intercorrelations and univariate correlations and wer...
... Title: Oral Cavity and Floor of the Mouth: Benign Tumors. Authors: Hermans, Robert Mancuso,An... more ... Title: Oral Cavity and Floor of the Mouth: Benign Tumors. Authors: Hermans, Robert Mancuso,Anthony Collins, William. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1844-1850. ...
... Title: Larynx: Introduction, Normal Anatomy and Function. Authors: Hermans, Robert Mancuso,An... more ... Title: Larynx: Introduction, Normal Anatomy and Function. Authors: Hermans, Robert Mancuso,Anthony. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1893-1924. ISBN: 978-1-60547-715-2. ...
International Journal of Radiation Oncology Biology Physics, Sep 1, 1999
Purpose: To determine if pre-radiotherapy (RT) and/or post-radiotherapy computed tomography (CT) ... more Purpose: To determine if pre-radiotherapy (RT) and/or post-radiotherapy computed tomography (CT) can predict local failure in patients with laryngeal carcinoma treated with definitive RT. Methods and Materials: The pre-and post-RT CT examinations of 59 patients (T3 glottic carcinoma [n ؍ 30] and T1-T4 supraglottic carcinoma [n ؍ 29]) were reviewed. For each patient, the first post-RT CT study between 1 and 6 months after irradiation was used. All patients were treated with definitive hyperfractionated twice-daily continuous-course irradiation to a total dose of 6,720-7,920 cGy, and followed-up clinically for at least 2 years after completion of RT. Local control was defined as absence of primary tumor recurrence and a functioning larynx. On the pre-treatment CT study, each tumor was assigned a high-or low-risk profile for local failure after RT. The post-RT CT examinations were evaluated for post-treatment changes using a three-point post-RT CT-score: 1 ؍ expected post-RT changes; 2 ؍ focal mass with a maximal diameter of < 1 cm and/or asymmetric obliteration of laryngeal tissue planes; 3 ؍ focal mass with a maximal diameter of > 1 cm, or < 50% estimated tumor volume reduction. Results: The local control rates at 2 years post-RT based on pre-treatment CT evaluation were 88% for low pre-treatment risk profile patients (95% CI: 66-96%) and 34% (95% CI: 19-50%) for high pre-treatment risk profile patients (risk ratio 6.583; 95% CI: 2.265-9.129; p ؍ 0.0001). Based on post-treatment CT, the local control rates at 2 years post-RT were 94% for score 1, 67% for score 2, and 10% for score 3 (risk ratio 4.760; 95% CI: 2.278-9.950 p ؍ 0.0001). Post-RT CT scores added significant information to the pre-treatment risk profiles on prognosis. Conclusions: Pre-treatment CT risk profiles, as well as post-RT CT evaluation can identify patients, irradiated for laryngeal carcinomas, at high risk for developing local failure. When the post-RT CT score is available, it proves to be an even better prognosticator than the pre-treatment CT-risk profile.
... Title: Larynx: Infectious and Noninfectious Inflammatory Diseases. Authors: Hermans, Robert M... more ... Title: Larynx: Infectious and Noninfectious Inflammatory Diseases. Authors: Hermans, Robert Mancuso, Anthony Collins, William. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1946-1963. ...
... Title: Oral Cavity: Infectious and Noninfectious Inflammatory Conditions. Authors: Hermans, R... more ... Title: Oral Cavity: Infectious and Noninfectious Inflammatory Conditions. Authors: Hermans, Robert Mancuso, Anthony Collins, William. Issue Date: 2010. Publisher: Wolter Kluwer/Lippincott Williams & Wilkins. Host Document: Head and Neck Radiology pages:1836-1845. ...
AJNR. American journal of neuroradiology, Jan 16, 2015
Acute invasive fungal rhinosinusitis carries a high mortality rate. An easy-to-use and accurate p... more Acute invasive fungal rhinosinusitis carries a high mortality rate. An easy-to-use and accurate predictive imaging model is currently lacking. We assessed the performance of various CT findings for the identification of acute invasive fungal rhinosinusitis and synthesized a simple and robust diagnostic model to serve as an easily applicable screening tool for at-risk patients. Two blinded neuroradiologists retrospectively graded 23 prespecified imaging abnormalities in the craniofacial region on craniofacial CT examinations from 42 patients with pathology-proven acute invasive fungal rhinosinusitis and 42 control patients proved negative for acute invasive fungal rhinosinusitis from the same high-risk population. A third blinded neuroradiologist decided discrepancies. Specificity, sensitivity, positive predictive value, and negative predictive value were determined for all individual variables. The 23 variables were evaluated for intercorrelations and univariate correlations and wer...