Voicu Dragos | Universitatea Dunarea de Jos Galati (original) (raw)
Papers by Voicu Dragos
Broad Research in Artificial Intelligence Neuroscience, Feb 6, 2024
Dentophobia is a significant problem in oral health management. In the conditions of the COVID-19... more Dentophobia is a significant problem in oral health management. In the conditions of the COVID-19 pandemic, with the associated sanitary measures (quarantine, social distancing) at national level, the fear and dental anxiety are supposedly increased, especially in children. Pediatric patients are emotionally affected when they faced with the need for emergency dental intervention. The current study seeks to assess the emotional state of children aged 8-12, who needed dental care during quarantine, at the regional level, as well as the degree of anxiety of their parents. Dental anxiety was assessed independently by the dentist, parents and children themselves. If in children, the level of dental anxiety increased insignificantly, compared to the pre-pandemic period, the levels of parental anxiety were higher. The boys in the pandemic group had a higher level of anxiety, especially in the parental assessment. The results suggest that the reorganization of oral care in the pandemic scenario did not have a major effect on children's dental anxiety. However, the results of the assessment in boys show that they may be more vulnerable and need special care to alleviate their anxiety and reduce their risk of dentophobia in the future. These conclusions should be treated with caution, given the small sample size, which requires further confirmation. It is also important to convince parents of the safety of a visit to the dentist during a pandemic, to minimize their anxiety about their children's dental fears.
BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE, Apr 14, 2020
Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiol... more Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiological and morphological changes, reflected by an abnormal response to regular medication and nutrients, with consequences on the efficiency of anesthesia and the surgical act. Material and methods. A retrospective study was conducted on the latest 1750 cases (2016-2018), hospitalized and operated, in which the preoperative identification of alcohol abuse was made by dosing biochemical markers (gamma-glutamyl transferase, poor carbohydrate transferrin and medium erythrocytic corpuscular volume), by standard questionnaires and, of course, by preanesthetic exam. Results and discussions. The study showed a rate of 8% (140 cases) of alcohol abuse among these surgical patients. The paper reviews the somatic complications of alcoholism: neurological, gastrointestinal, cardiovascular, metabolic, hematological, immunological and hormonal, and discusses the effectiveness of the study method. Conclusions. It is proposed to implement a preoperative identification protocol for patients with alcoholism to prevent postoperative withdrawal.
BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE, Apr 14, 2020
Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiol... more Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiological and morphological changes, reflected by an abnormal response to regular medication and nutrients, with consequences on the efficiency of anesthesia and the surgical act. Material and methods. A retrospective study was conducted on the latest 1750 cases (2016-2018), hospitalized and operated, in which the preoperative identification of alcohol abuse was made by dosing biochemical markers (gamma-glutamyl transferase, poor carbohydrate transferrin and medium erythrocytic corpuscular volume), by standard questionnaires and, of course, by preanesthetic exam. Results and discussions. The study showed a rate of 8% (140 cases) of alcohol abuse among these surgical patients. The paper reviews the somatic complications of alcoholism: neurological, gastrointestinal, cardiovascular, metabolic, hematological, immunological and hormonal, and discusses the effectiveness of the study method. Conclusions. It is proposed to implement a preoperative identification protocol for patients with alcoholism to prevent postoperative withdrawal.
Journal of Systems and Software, 2020
Postoperative complications are common in patients with complicated colon cancers operated in Eme... more Postoperative complications are common in patients with complicated colon cancers operated in Emergency. Most complications are those of the sound (suppurations, hematoma, dehiscence), postoperative ileus, anastomotic fistula. The purpose of this study is to evaluate the influence of the duration of the surgery on the postoperative complications in patients with complicated colon tumors, operated in emergency. We made a retrospective study on 451 patients treated for complicated colon cancers in the surgery clinics I and II of the Clinical Emergency County Hospital Galați between 2008 and 2017. In this study, we found all the 3 types of complications of colon tumors, but the most common was the intestinal obstruction. The operations varied from colostomies to subtotal and total colectomies. Most complications occured on the postoperatory days 4-8. The statistical analysis that we made revealed important statistical significance in the correlation of the postoperative complications a...
CARMEN TIUTIUCA1, DRAGOS VOICU1*, ISABELLA BRUJBU2, LUANA MACOVEI2, CORINA CUPILAN3, CAMELIA BOGD... more CARMEN TIUTIUCA1, DRAGOS VOICU1*, ISABELLA BRUJBU2, LUANA MACOVEI2, CORINA CUPILAN3, CAMELIA BOGDANICI4, VIRGIL BULIMAR2 1 Dunarea de jos University of Galati. Faculty of Medicine and Pharmacy, 47, Domneasca Str., 800008, Galati, Romania 2 Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, 16 Universitatii Str., 700115, Iasi, Romania 3 Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, Department of Anatomy, 16 Universitatii Str., 700115, Iasi, Romania 4 Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, Department of Surgery II, 16 Universitatii Str., 700115, Iasi, Romania
The complexity of medical and social aspects of human reproduction is well-known. Social, economi... more The complexity of medical and social aspects of human reproduction is well-known. Social, economic factors, family, culture, legal institutions, political and religious convictions condition the psychology of the individual and his attitude towards reproduction. Abortion was seen over time as a sensitive multi-faceted issue. It is a demographic issue, as too many abortions led to imbalances in population structure, birth rate decrease and prevalence of older ages over younger ones and is the main cause of maternal mortality. It is an economic issue because abortions led to lower production capacities and extended leaves of absence. By its lethal risks, infertility involved, extrauterine pregnancies, miscarriages, mostly in younger women, abortion is a topical medical issue. With regard to the mentality it determined in relations between sexes, it is also an ethical issue. This subject matter is tackled as there are scores of induced septic abortions, maternal deaths and severe compl...
Background: Although unrecognized, early postoperative delirium and cognitive dysfunction in the ... more Background: Although unrecognized, early postoperative delirium and cognitive dysfunction in the Intensive Care Unit (ICU) are relatively common. Aim: The present study has proposed to identify the risk factors for delirium and their early incidence after surgery, with a view to implementing a screening list for delirium in ICU (ICDSL). Method: 722 patients undergoing abdominal surgery, with general anesthesia, were prospectively monitored for the development of postoperative delirium during Intensive Care Unit (ICU) stay. Results: The incidence of postoperative delirium was 8.03% (58 cases). No statistically relevant prolongation predictors for delirium were found. The duration of surgery was double, thus significantly higher in the delirium group (2.5 ± 1 vs 1 ± 0.87 hours). Patients in the delusion group were transfused with blood products, had episodes of intraoperative cardiocirculatory decline, underwent protracted mechanical ventilation (averaging 1.15 hours longer), and the ...
We intend to present the results of an on-going study started in pandemic concerning dentophobia ... more We intend to present the results of an on-going study started in pandemic concerning dentophobia as a health problem. Our aim was to correlate the level of health education with the feeling of fear of dentistry and anxiety in young population during the pandemic. We used an anonymous online questionnaire on a group of 45 subjects aged 18-55. The results of this on-going study up to this stage show that despite the pandemic, there is a concern of young adults about about oral hygiene and dental issues as part of the overall health of the subjects investigated. The need to implement psycho-educational dentistry programs still exists.
BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE, Apr 14, 2020
Introduction. Hepatic encephalopathy comprises a broad spectrum of neuropsychiatric manifestation... more Introduction. Hepatic encephalopathy comprises a broad spectrum of neuropsychiatric manifestations, commonly encountered in patients with hepatic dysfunction, in the absence of other concomitant causes of cerebral infarction. Under these conditions, varying degrees of consciousness, neuromuscular dysfunction, cognitive, behavioral and emotional deficits coexist. Minimal hepatic encephalopathy (MHE) is defined by a normal neurological clinical examination but with cognitive deficits that can be highlighted by neuropsychological testing. Material and Methods. A retrospective study was conducted on the latest 100 patients (2016-2018), traumatized in road accidents or dropping from their own level, the direct causes of which were apparently inexplicable. The methods included psychometric tests. Results and Discussion. If 78 patients were known with hepatic cirrhosis and episodically manifested encephalopathy, 20 of them were in treatment for major liver dysfunction, but without encephalopathy, and for 2 patients, the revealing element of hepatic suffering was latent encephalopathy, diagnosed after the road accident. The paper discusses the pathogenesis of hepatic encephalopathy, diagnostic difficulties and its practical implications. Conclusions. The current gold standard for MHE diagnosis is psychometric testing, which should be completed and revised as MHE is a major public health issue, associating with the risk of unprovoked falls and road accidents. MHE detection, sometimes as the first sign of decompensation of an ignored liver disease, but always as a prodrome of clinically manifest encephalopathy, requires specialized treatment and monitoring.
The cystic pancreatic neoplasias are very rare (only 1-2 % of the exocrine pancreatic tumours) an... more The cystic pancreatic neoplasias are very rare (only 1-2 % of the exocrine pancreatic tumours) and, because of their clinical and biological characteristics, they can be treated by surgery in a effective way, as simple excision, with a good prognosis. Despite the histological analogies, the 5 types of cystadenomas vary by their dimensions, localization and biology; the serous solid adenoma is the most rare of the 5 types. The paper presents aspects from 4 young patients admitted for severe superior abdominal pain. The MRI examination revealed hypervascular mass, well delimited, situated between the pancreatic tail and the spleen. In each case have been practiced the excision of the tumour by spleen distal pancreatectomy. The histological and imunohistochemical examinations established the diagnosis: solid serous pancreatic adenoma. Taking into account that the malignity is hard to be suspected even intraoperatory, the surgical excision is the most effective treatment. The surgical e...
Journal of Surgical Sciences
In 1826, Lisfranc practiced a perineal circular incision, without opening the peritoneum. 50 year... more In 1826, Lisfranc practiced a perineal circular incision, without opening the peritoneum. 50 years later, Verneuil and then Dolbeau and Denonvilliers practiced more extensive resections. In 1907, Lockart-Mummery described the operation that bears his name. In 1875, Kocher and Volkmann used the sacral approach that has been popularized by Kraske. Later, it became well known in the whole world and, with some little changes, it has been used in Europe by Bardenhaver, Hochenegg, Billroth, Rehn, Heinike and Rygidier and in the USA by Harrison Cripps, Edwards, Bevan and Grey Turner. Almost all of them resected the rectum and reestablished the continuity with a primary anastomosis. It seems that Volkmann practiced the combined abdominal and perineal approach for the first time in 1877, followed by Czerny and Köenning. Between 1896-1899, Quenu popularized this technique. In 1908, Ernest Miles began to use the technique and in 1914 he published the results. The resection of the posterior wal...
Chirurgia
Introducere: În anul 2018 cancerul de colon se afla pe locul al 5-lea ca mortalitate prin cancer,... more Introducere: În anul 2018 cancerul de colon se afla pe locul al 5-lea ca mortalitate prin cancer, iar cancerul rectal pe locul al 10-lea. Supravieţuirea la distanţă a bolnavilor cu cancer colorectal operat în urgenţă, rămâne nesatisfăcătoare, decesul fiind datorat recidivelor locale şi a metastazelor. Scopul: Evaluarea unor corelaţii ale supravieţuirii globale cu caracteristici clinico-paraclinice, tumorale sau de tratament pentru identificarea factorilor de prognostic la pacienţii cu cancer colorectal operat în urgenţă. Material şi Metode: Am efectuat o analiză retrospectivă la 431 pacienţi cu cancer colorectal operat în urgenţă în perioada 2008-2017, cu excluderea celor 40 de pacienţi cu decese postoperatorii, cu o perioadă de urmărire de cel puţin un an. S-au efectuat corelaţii ale unor caracteristici clinico-paraclinice, tumorale sau de tratament cu supravieţuirea globală. Rezultate: În analiza statistic univariată de supravieţuire, se obţine o asociere semnificativă statistic cu: vârsta > 61 ani (p_value = 0.000049), antecedentele chirurgicale abdominal (p_value = 0,031725), bolile cardiace (p_value = 0,000007), fibrilaţia atrială (p_value = 0,007496), diagnosticul la internare (p_value = 0,034352), caşexia (p_value = 0,000000), oligoanuria (p_value = 0,000000), anemia (p_value = 0,000006) dezechilibrul hidroelectrolitic (p_value = 0,000001), localizarea tumorală (p_value = 0,000030), invazia în organele vecine (p_value = 0,000000), aspectul de pelvis îngheţat (p_value = 0,000000), carcinomatoza peritoneală (p_value = 0,000000), metastazele hepatice (p_value=0,000000), tipul de intervenţie chirurgicală (p_value = 0,000000), limfodisecţia (p_value = 0,000001), biopsia hepatică (p_value = 0,043483), reintegrarea tranzitului intestinal (p_value = 0,000000), intervenţiile seriate (p_value = 0,000000), pTNM (p_value = 0,000000), gradingul (p_value = 0,007069). Analiza de regresie multivariată Cox a arătat că: vârsta > 61 ani-HR=1.026, 95%CI(1.012, 1.039) (p_value = 0.000139), caşexia-HR = 1.358, 95%CI(1.046, 1.764) (p_value = 0,021617), carcinomatoza peritoneală-HR = 2.346, 95%CI(1.163, 4.732) (p_value = 0,017253), stadiul bolii-HR=36.745, 95%CI = (14.778, 91.366) (p_ value = 0,000000), tipul de intervenţie-HR = 0.187, 95%CI(0.045, 0.779) (p_ value = 0,021281) şi intervenţiile seriate-HR = 0.282, 95% CI(0.144,0.551) (p_ value = 000213) sunt factori de prognostic independenţi. Concluzii: Factorii de prognostic pentru bolnavii cu cancere colorectale operate în urgenţă sunt: vârsta > 61 ani, prezenţa antecedentelor chirurgicale abdominale şi a tarelor cardiace asociate, în special a fibrilaţiei atriale, diagnosticul de iminenţă de perforaţie diastatică, caşexia, oligoanuria, anemia şi dezechilibrul hidro-electrolitic prezente la internare, tumorile rectale, invazia tumorală în organe vecine, aspectul de "pelvis îngheţat", prezenţa metastazelor hepatice sau a carcinomatozei peritoneale, tumorile nediferenţiate, stadiul III sau IV, practicarea unei derivaţii interne sau neefectuarea limfodisecţiei. Vârsta peste 61 de ani, caşexia, precum şi carcinomatoza peritoneală sunt factori de risc independenţi, iar, operaţia Hartmann şi intervenţiile seriate sunt factori de protecţie independenţi. Cuvinte cheie: cancer colorectal, factori de pronostic, urgenţă, tratament chirurgical
Acute and Chronic Pancreatitis, 2015
Terminal or lateral colostomy is a surgical operation, commonly used in colorectal surgery, manda... more Terminal or lateral colostomy is a surgical operation, commonly used in colorectal surgery, mandatory in interventions such as rectal amputation or Hartmann surgery, or colon decompression and anastomosis protection. Colostomies are encumbered, however, by a series of complications, some of them are major and very difficult to solve. The most common are: ischemia and loop regression, peristomal hernia, stenosis, prolapse, peristomal fistula. Much less rarely are described: intrastomal hernia, peristomalphlegmon and stercoral peritonitis. The authors report, during the period 2013-2017, 119 temporary or definitive colostomies, that have been performed in the therapeutic context of colorectal neoplasic pathology. In those 119 colostomies, a number of 13 serious complications was noted (11%), plus 18 transient minor complications (15%) reprezented by skin irritations in peristomal region. The paper presents the main diagnostic and therapeutic aspects in cases with complicated colostomy. Colostomy is still quite frequently used in surgical services, often representing the solution that takes the the patient out of a difficult situation; it should not be considered a handicap under the conditions of an adequate psycho-socio-medical climate. Complications of colostomies are relatively rare, but some of these are difficult to solve as they address patients with multiple comorbidities. As important as the technical execution of the colostomies is their subsequent care, the idea of training specialized personnel for their care -stomatherapists is not far-fetched.
Broad Research in Artificial Intelligence Neuroscience, Feb 6, 2024
Dentophobia is a significant problem in oral health management. In the conditions of the COVID-19... more Dentophobia is a significant problem in oral health management. In the conditions of the COVID-19 pandemic, with the associated sanitary measures (quarantine, social distancing) at national level, the fear and dental anxiety are supposedly increased, especially in children. Pediatric patients are emotionally affected when they faced with the need for emergency dental intervention. The current study seeks to assess the emotional state of children aged 8-12, who needed dental care during quarantine, at the regional level, as well as the degree of anxiety of their parents. Dental anxiety was assessed independently by the dentist, parents and children themselves. If in children, the level of dental anxiety increased insignificantly, compared to the pre-pandemic period, the levels of parental anxiety were higher. The boys in the pandemic group had a higher level of anxiety, especially in the parental assessment. The results suggest that the reorganization of oral care in the pandemic scenario did not have a major effect on children's dental anxiety. However, the results of the assessment in boys show that they may be more vulnerable and need special care to alleviate their anxiety and reduce their risk of dentophobia in the future. These conclusions should be treated with caution, given the small sample size, which requires further confirmation. It is also important to convince parents of the safety of a visit to the dentist during a pandemic, to minimize their anxiety about their children's dental fears.
BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE, Apr 14, 2020
Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiol... more Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiological and morphological changes, reflected by an abnormal response to regular medication and nutrients, with consequences on the efficiency of anesthesia and the surgical act. Material and methods. A retrospective study was conducted on the latest 1750 cases (2016-2018), hospitalized and operated, in which the preoperative identification of alcohol abuse was made by dosing biochemical markers (gamma-glutamyl transferase, poor carbohydrate transferrin and medium erythrocytic corpuscular volume), by standard questionnaires and, of course, by preanesthetic exam. Results and discussions. The study showed a rate of 8% (140 cases) of alcohol abuse among these surgical patients. The paper reviews the somatic complications of alcoholism: neurological, gastrointestinal, cardiovascular, metabolic, hematological, immunological and hormonal, and discusses the effectiveness of the study method. Conclusions. It is proposed to implement a preoperative identification protocol for patients with alcoholism to prevent postoperative withdrawal.
BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE, Apr 14, 2020
Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiol... more Background. Alcoholism is a public health problem. Chronic ethanol consumption determines physiological and morphological changes, reflected by an abnormal response to regular medication and nutrients, with consequences on the efficiency of anesthesia and the surgical act. Material and methods. A retrospective study was conducted on the latest 1750 cases (2016-2018), hospitalized and operated, in which the preoperative identification of alcohol abuse was made by dosing biochemical markers (gamma-glutamyl transferase, poor carbohydrate transferrin and medium erythrocytic corpuscular volume), by standard questionnaires and, of course, by preanesthetic exam. Results and discussions. The study showed a rate of 8% (140 cases) of alcohol abuse among these surgical patients. The paper reviews the somatic complications of alcoholism: neurological, gastrointestinal, cardiovascular, metabolic, hematological, immunological and hormonal, and discusses the effectiveness of the study method. Conclusions. It is proposed to implement a preoperative identification protocol for patients with alcoholism to prevent postoperative withdrawal.
Journal of Systems and Software, 2020
Postoperative complications are common in patients with complicated colon cancers operated in Eme... more Postoperative complications are common in patients with complicated colon cancers operated in Emergency. Most complications are those of the sound (suppurations, hematoma, dehiscence), postoperative ileus, anastomotic fistula. The purpose of this study is to evaluate the influence of the duration of the surgery on the postoperative complications in patients with complicated colon tumors, operated in emergency. We made a retrospective study on 451 patients treated for complicated colon cancers in the surgery clinics I and II of the Clinical Emergency County Hospital Galați between 2008 and 2017. In this study, we found all the 3 types of complications of colon tumors, but the most common was the intestinal obstruction. The operations varied from colostomies to subtotal and total colectomies. Most complications occured on the postoperatory days 4-8. The statistical analysis that we made revealed important statistical significance in the correlation of the postoperative complications a...
CARMEN TIUTIUCA1, DRAGOS VOICU1*, ISABELLA BRUJBU2, LUANA MACOVEI2, CORINA CUPILAN3, CAMELIA BOGD... more CARMEN TIUTIUCA1, DRAGOS VOICU1*, ISABELLA BRUJBU2, LUANA MACOVEI2, CORINA CUPILAN3, CAMELIA BOGDANICI4, VIRGIL BULIMAR2 1 Dunarea de jos University of Galati. Faculty of Medicine and Pharmacy, 47, Domneasca Str., 800008, Galati, Romania 2 Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, 16 Universitatii Str., 700115, Iasi, Romania 3 Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, Department of Anatomy, 16 Universitatii Str., 700115, Iasi, Romania 4 Gr. T. Popa University of Medicine and Pharmacy, Faculty of Medicine, Department of Surgery II, 16 Universitatii Str., 700115, Iasi, Romania
The complexity of medical and social aspects of human reproduction is well-known. Social, economi... more The complexity of medical and social aspects of human reproduction is well-known. Social, economic factors, family, culture, legal institutions, political and religious convictions condition the psychology of the individual and his attitude towards reproduction. Abortion was seen over time as a sensitive multi-faceted issue. It is a demographic issue, as too many abortions led to imbalances in population structure, birth rate decrease and prevalence of older ages over younger ones and is the main cause of maternal mortality. It is an economic issue because abortions led to lower production capacities and extended leaves of absence. By its lethal risks, infertility involved, extrauterine pregnancies, miscarriages, mostly in younger women, abortion is a topical medical issue. With regard to the mentality it determined in relations between sexes, it is also an ethical issue. This subject matter is tackled as there are scores of induced septic abortions, maternal deaths and severe compl...
Background: Although unrecognized, early postoperative delirium and cognitive dysfunction in the ... more Background: Although unrecognized, early postoperative delirium and cognitive dysfunction in the Intensive Care Unit (ICU) are relatively common. Aim: The present study has proposed to identify the risk factors for delirium and their early incidence after surgery, with a view to implementing a screening list for delirium in ICU (ICDSL). Method: 722 patients undergoing abdominal surgery, with general anesthesia, were prospectively monitored for the development of postoperative delirium during Intensive Care Unit (ICU) stay. Results: The incidence of postoperative delirium was 8.03% (58 cases). No statistically relevant prolongation predictors for delirium were found. The duration of surgery was double, thus significantly higher in the delirium group (2.5 ± 1 vs 1 ± 0.87 hours). Patients in the delusion group were transfused with blood products, had episodes of intraoperative cardiocirculatory decline, underwent protracted mechanical ventilation (averaging 1.15 hours longer), and the ...
We intend to present the results of an on-going study started in pandemic concerning dentophobia ... more We intend to present the results of an on-going study started in pandemic concerning dentophobia as a health problem. Our aim was to correlate the level of health education with the feeling of fear of dentistry and anxiety in young population during the pandemic. We used an anonymous online questionnaire on a group of 45 subjects aged 18-55. The results of this on-going study up to this stage show that despite the pandemic, there is a concern of young adults about about oral hygiene and dental issues as part of the overall health of the subjects investigated. The need to implement psycho-educational dentistry programs still exists.
BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE, Apr 14, 2020
Introduction. Hepatic encephalopathy comprises a broad spectrum of neuropsychiatric manifestation... more Introduction. Hepatic encephalopathy comprises a broad spectrum of neuropsychiatric manifestations, commonly encountered in patients with hepatic dysfunction, in the absence of other concomitant causes of cerebral infarction. Under these conditions, varying degrees of consciousness, neuromuscular dysfunction, cognitive, behavioral and emotional deficits coexist. Minimal hepatic encephalopathy (MHE) is defined by a normal neurological clinical examination but with cognitive deficits that can be highlighted by neuropsychological testing. Material and Methods. A retrospective study was conducted on the latest 100 patients (2016-2018), traumatized in road accidents or dropping from their own level, the direct causes of which were apparently inexplicable. The methods included psychometric tests. Results and Discussion. If 78 patients were known with hepatic cirrhosis and episodically manifested encephalopathy, 20 of them were in treatment for major liver dysfunction, but without encephalopathy, and for 2 patients, the revealing element of hepatic suffering was latent encephalopathy, diagnosed after the road accident. The paper discusses the pathogenesis of hepatic encephalopathy, diagnostic difficulties and its practical implications. Conclusions. The current gold standard for MHE diagnosis is psychometric testing, which should be completed and revised as MHE is a major public health issue, associating with the risk of unprovoked falls and road accidents. MHE detection, sometimes as the first sign of decompensation of an ignored liver disease, but always as a prodrome of clinically manifest encephalopathy, requires specialized treatment and monitoring.
The cystic pancreatic neoplasias are very rare (only 1-2 % of the exocrine pancreatic tumours) an... more The cystic pancreatic neoplasias are very rare (only 1-2 % of the exocrine pancreatic tumours) and, because of their clinical and biological characteristics, they can be treated by surgery in a effective way, as simple excision, with a good prognosis. Despite the histological analogies, the 5 types of cystadenomas vary by their dimensions, localization and biology; the serous solid adenoma is the most rare of the 5 types. The paper presents aspects from 4 young patients admitted for severe superior abdominal pain. The MRI examination revealed hypervascular mass, well delimited, situated between the pancreatic tail and the spleen. In each case have been practiced the excision of the tumour by spleen distal pancreatectomy. The histological and imunohistochemical examinations established the diagnosis: solid serous pancreatic adenoma. Taking into account that the malignity is hard to be suspected even intraoperatory, the surgical excision is the most effective treatment. The surgical e...
Journal of Surgical Sciences
In 1826, Lisfranc practiced a perineal circular incision, without opening the peritoneum. 50 year... more In 1826, Lisfranc practiced a perineal circular incision, without opening the peritoneum. 50 years later, Verneuil and then Dolbeau and Denonvilliers practiced more extensive resections. In 1907, Lockart-Mummery described the operation that bears his name. In 1875, Kocher and Volkmann used the sacral approach that has been popularized by Kraske. Later, it became well known in the whole world and, with some little changes, it has been used in Europe by Bardenhaver, Hochenegg, Billroth, Rehn, Heinike and Rygidier and in the USA by Harrison Cripps, Edwards, Bevan and Grey Turner. Almost all of them resected the rectum and reestablished the continuity with a primary anastomosis. It seems that Volkmann practiced the combined abdominal and perineal approach for the first time in 1877, followed by Czerny and Köenning. Between 1896-1899, Quenu popularized this technique. In 1908, Ernest Miles began to use the technique and in 1914 he published the results. The resection of the posterior wal...
Chirurgia
Introducere: În anul 2018 cancerul de colon se afla pe locul al 5-lea ca mortalitate prin cancer,... more Introducere: În anul 2018 cancerul de colon se afla pe locul al 5-lea ca mortalitate prin cancer, iar cancerul rectal pe locul al 10-lea. Supravieţuirea la distanţă a bolnavilor cu cancer colorectal operat în urgenţă, rămâne nesatisfăcătoare, decesul fiind datorat recidivelor locale şi a metastazelor. Scopul: Evaluarea unor corelaţii ale supravieţuirii globale cu caracteristici clinico-paraclinice, tumorale sau de tratament pentru identificarea factorilor de prognostic la pacienţii cu cancer colorectal operat în urgenţă. Material şi Metode: Am efectuat o analiză retrospectivă la 431 pacienţi cu cancer colorectal operat în urgenţă în perioada 2008-2017, cu excluderea celor 40 de pacienţi cu decese postoperatorii, cu o perioadă de urmărire de cel puţin un an. S-au efectuat corelaţii ale unor caracteristici clinico-paraclinice, tumorale sau de tratament cu supravieţuirea globală. Rezultate: În analiza statistic univariată de supravieţuire, se obţine o asociere semnificativă statistic cu: vârsta > 61 ani (p_value = 0.000049), antecedentele chirurgicale abdominal (p_value = 0,031725), bolile cardiace (p_value = 0,000007), fibrilaţia atrială (p_value = 0,007496), diagnosticul la internare (p_value = 0,034352), caşexia (p_value = 0,000000), oligoanuria (p_value = 0,000000), anemia (p_value = 0,000006) dezechilibrul hidroelectrolitic (p_value = 0,000001), localizarea tumorală (p_value = 0,000030), invazia în organele vecine (p_value = 0,000000), aspectul de pelvis îngheţat (p_value = 0,000000), carcinomatoza peritoneală (p_value = 0,000000), metastazele hepatice (p_value=0,000000), tipul de intervenţie chirurgicală (p_value = 0,000000), limfodisecţia (p_value = 0,000001), biopsia hepatică (p_value = 0,043483), reintegrarea tranzitului intestinal (p_value = 0,000000), intervenţiile seriate (p_value = 0,000000), pTNM (p_value = 0,000000), gradingul (p_value = 0,007069). Analiza de regresie multivariată Cox a arătat că: vârsta > 61 ani-HR=1.026, 95%CI(1.012, 1.039) (p_value = 0.000139), caşexia-HR = 1.358, 95%CI(1.046, 1.764) (p_value = 0,021617), carcinomatoza peritoneală-HR = 2.346, 95%CI(1.163, 4.732) (p_value = 0,017253), stadiul bolii-HR=36.745, 95%CI = (14.778, 91.366) (p_ value = 0,000000), tipul de intervenţie-HR = 0.187, 95%CI(0.045, 0.779) (p_ value = 0,021281) şi intervenţiile seriate-HR = 0.282, 95% CI(0.144,0.551) (p_ value = 000213) sunt factori de prognostic independenţi. Concluzii: Factorii de prognostic pentru bolnavii cu cancere colorectale operate în urgenţă sunt: vârsta > 61 ani, prezenţa antecedentelor chirurgicale abdominale şi a tarelor cardiace asociate, în special a fibrilaţiei atriale, diagnosticul de iminenţă de perforaţie diastatică, caşexia, oligoanuria, anemia şi dezechilibrul hidro-electrolitic prezente la internare, tumorile rectale, invazia tumorală în organe vecine, aspectul de "pelvis îngheţat", prezenţa metastazelor hepatice sau a carcinomatozei peritoneale, tumorile nediferenţiate, stadiul III sau IV, practicarea unei derivaţii interne sau neefectuarea limfodisecţiei. Vârsta peste 61 de ani, caşexia, precum şi carcinomatoza peritoneală sunt factori de risc independenţi, iar, operaţia Hartmann şi intervenţiile seriate sunt factori de protecţie independenţi. Cuvinte cheie: cancer colorectal, factori de pronostic, urgenţă, tratament chirurgical
Acute and Chronic Pancreatitis, 2015
Terminal or lateral colostomy is a surgical operation, commonly used in colorectal surgery, manda... more Terminal or lateral colostomy is a surgical operation, commonly used in colorectal surgery, mandatory in interventions such as rectal amputation or Hartmann surgery, or colon decompression and anastomosis protection. Colostomies are encumbered, however, by a series of complications, some of them are major and very difficult to solve. The most common are: ischemia and loop regression, peristomal hernia, stenosis, prolapse, peristomal fistula. Much less rarely are described: intrastomal hernia, peristomalphlegmon and stercoral peritonitis. The authors report, during the period 2013-2017, 119 temporary or definitive colostomies, that have been performed in the therapeutic context of colorectal neoplasic pathology. In those 119 colostomies, a number of 13 serious complications was noted (11%), plus 18 transient minor complications (15%) reprezented by skin irritations in peristomal region. The paper presents the main diagnostic and therapeutic aspects in cases with complicated colostomy. Colostomy is still quite frequently used in surgical services, often representing the solution that takes the the patient out of a difficult situation; it should not be considered a handicap under the conditions of an adequate psycho-socio-medical climate. Complications of colostomies are relatively rare, but some of these are difficult to solve as they address patients with multiple comorbidities. As important as the technical execution of the colostomies is their subsequent care, the idea of training specialized personnel for their care -stomatherapists is not far-fetched.