Alessandro Silveira | FURB - Fundação Universidade Regional de Blumenau (original) (raw)

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Papers by Alessandro Silveira

Research paper thumbnail of MRSA from Santa Catarina State, Southern Brazil: intriguing epidemiological differences compared to other Brazilian regions

The Brazilian Journal of Infectious Diseases, 2015

Research paper thumbnail of EVALUATION OF METHODS IN DETECTING VANCOMYCIN MIC AMONG MRSA ISOLATES AND THE CHANGES IN ACCURACY RELATED TO DIFFERENT MIC VALUES

Revista do Instituto de Medicina Tropical de São Paulo, 2014

Research paper thumbnail of Analysis of 724 cases of primary head and neck squamous cell carcinoma (HNSCC) with a focus on young patients and p53 immunolocalization

Oral Oncology, 2009

Head and neck Epidemiology Young people Risk factors p53 Protein Immunohistochemical Prognostic s... more Head and neck Epidemiology Young people Risk factors p53 Protein Immunohistochemical Prognostic s u m m a r y

Research paper thumbnail of Is prediffusion test an alternative to improve accuracy in screening hVISA strains and to detect susceptibility to glycopeptides/lipopeptides?

Diagnostic Microbiology and Infectious Disease, 2014

The characterization of heteroresistant vancomycin-intermediate Staphylococcus aureus strains (hV... more The characterization of heteroresistant vancomycin-intermediate Staphylococcus aureus strains (hVISA) is even more challenging, as no routine standardized laboratory methods are available. A total of 124 S. aureus isolates recovered from inpatients attended in hospitals of Santa Catarina State, Southern Brazil, were evaluated. The MIC of vancomycin, teicoplanin, and daptomycin was determined by Etest and prediffusion tests using NeoSensitabs® tablets. All isolates were susceptible to vancomycin (MICs: 0.5-3 μg/mL) by Etest. However, according to prediffusion test, 17 isolates presented reduced susceptibility to vancomycin, and of these, 12 were confirmed as hVISA using populational analysis. Considering daptomycin, prediffusion results were in agreement with susceptibility data (MICs), as all isolates were susceptible. Considering that characterizing hVISA is challenging and that MIC determination is not adequate to characterize this phenotype, prediffusion test was a viable alternative to screening hVISA and reduced susceptibility to vancomycin. It was simple and low cost, with accuracy comparable to other well-established methods.

Research paper thumbnail of MRSA from Santa Catarina State, Southern Brazil: intriguing epidemiological differences compared to other Brazilian regions

The Brazilian Journal of Infectious Diseases, 2015

Research paper thumbnail of EVALUATION OF METHODS IN DETECTING VANCOMYCIN MIC AMONG MRSA ISOLATES AND THE CHANGES IN ACCURACY RELATED TO DIFFERENT MIC VALUES

Revista do Instituto de Medicina Tropical de São Paulo, 2014

Research paper thumbnail of Analysis of 724 cases of primary head and neck squamous cell carcinoma (HNSCC) with a focus on young patients and p53 immunolocalization

Oral Oncology, 2009

Head and neck Epidemiology Young people Risk factors p53 Protein Immunohistochemical Prognostic s... more Head and neck Epidemiology Young people Risk factors p53 Protein Immunohistochemical Prognostic s u m m a r y

Research paper thumbnail of Is prediffusion test an alternative to improve accuracy in screening hVISA strains and to detect susceptibility to glycopeptides/lipopeptides?

Diagnostic Microbiology and Infectious Disease, 2014

The characterization of heteroresistant vancomycin-intermediate Staphylococcus aureus strains (hV... more The characterization of heteroresistant vancomycin-intermediate Staphylococcus aureus strains (hVISA) is even more challenging, as no routine standardized laboratory methods are available. A total of 124 S. aureus isolates recovered from inpatients attended in hospitals of Santa Catarina State, Southern Brazil, were evaluated. The MIC of vancomycin, teicoplanin, and daptomycin was determined by Etest and prediffusion tests using NeoSensitabs® tablets. All isolates were susceptible to vancomycin (MICs: 0.5-3 μg/mL) by Etest. However, according to prediffusion test, 17 isolates presented reduced susceptibility to vancomycin, and of these, 12 were confirmed as hVISA using populational analysis. Considering daptomycin, prediffusion results were in agreement with susceptibility data (MICs), as all isolates were susceptible. Considering that characterizing hVISA is challenging and that MIC determination is not adequate to characterize this phenotype, prediffusion test was a viable alternative to screening hVISA and reduced susceptibility to vancomycin. It was simple and low cost, with accuracy comparable to other well-established methods.

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