Cansu Alpaslan | Gazi University (original) (raw)

Papers by Cansu Alpaslan

DergiPark (Istanbul University), Nov 2, 2014

Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi, 1995

Atatürk Üniversitesi Diş Hekimliği Fakültesi dergisi, 1995

Journal of Oral Rehabilitation, Jun 7, 2017

This study was conducted to evaluate whether integrating a nociceptive trigeminal inhibition-tens... more This study was conducted to evaluate whether integrating a nociceptive trigeminal inhibition-tension suppression system (NTI-tss) device with first-line therapy of myofascial pain, which includes guidance, assurance, counselling and behavioural changes, would be more effective in alleviating symptoms. This randomised controlled clinical trial included 40 patients who were clinically diagnosed with myofascial pain according to Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Patients were randomly divided into two groups: the first group comprised patients who received guidance, assurance, counselling and behavioural changes; an NTI-tss device was integrated to this protocol in the second group. Both groups exhibited reduction in pain levels and improvement of jaw function compared with baseline values, but the difference was not significant. Both groups demonstrated improvements in 6 weeks; however, the integration of NTI-tss device into the therapy protocol did not provide any additional benefit in relieving symptoms of myofascial pain.

Acta odontologica turcica, Sep 1, 2021

OBJECTIVE: The study aims to evaluate the presence of temporomandibular disorders (TMD) and their... more OBJECTIVE: The study aims to evaluate the presence of temporomandibular disorders (TMD) and their severity in asymptomatic and healthy individuals using the Fonseca anamnestic index. MATERIALS AND METHOD: A total of 135 individuals (80 females and 55 males, mean age 34.4±10.9) were involved in the study. The Fonseca anamnestic index was administered to the individuals. The data analysis was conducted by using Pearson's chi-squared test, Fisher's exact test, one-way ANOVA, and Spearman's correlation. RESULTS: TMD was detected in 63% of the individuals. Most of them (40%) had mild TMD. The difference between gender and TMD severity was statistically significant (p=0.001). Temporomandibular joint (TMJ) pain showed a statistically significant positive correlation with headache and emotional stress (r=0.312, p˂0.001; r=0.299, p˂0.001, respectively). TMJ pain showed the strongest positive correlation with clicking (r=0.443, p˂0.001). Bruxism showed positive correlations with the TMJ pain and clicking (r=0.197, p=0.022 and r= 0.221, p=0.010, respectively). CONCLUSION: The Fonseca anamnestic index is a reliable diagnostic tool that can be used to detect TMD-related symptoms and severity even in asymptomatic and healthy participants, providing rapid results in clinical practice.

Journal of Oral and Maxillofacial Surgery, Jun 1, 2001

Purpose This study was designed to investigate the efficacy of arthrocentesis on mouth opening an... more Purpose This study was designed to investigate the efficacy of arthrocentesis on mouth opening and pain in the treatment of temporomandibular joint (TMJ) internal derangement patients. Materials and Methods Fifteen males and 25 females aged between 18 and 37 years comprised the study material in the department of oral and maxillofacial surgery at Govt Dental College Srinagar (India). The patients' complaints were limited mouth opening and TMJ pain. Arthrocentesis was performed under aseptic conditions. Clinical evaluation of the patients was done before the procedure, and 1 week and 4 months post-operatively. Intensity of TMJ pain and maximal mouth opening were recorded at each follow-up visit. Results There was significant improvement in mouth opening and reduction in pain scores in the post-operative period. Conclusions Arthrocentesis is a simple and safe procedure for patients of internal derangement with closed lock for improving mouth opening and decreasing pain.

International Journal of Oral and Maxillofacial Surgery, Oct 1, 2013

DergiPark (Istanbul University), May 1, 2000

Shahid Beheshti University Dental Journal, Mar 10, 2017

Objectives: This study was undertaken to observe the frequency of different diagnostic groups for... more Objectives: This study was undertaken to observe the frequency of different diagnostic groups for temporomandibular disorders (TMDs) in patients who sought treatment for TMD in an outpatient clinic of a dental school. Methods: Files of patients who received a diagnosis of TMD in a period of 24 months were evaluated. Clinical and demographic data extracted from 213 patient files meeting the inclusion criteria were analyzed. Results: According to the classification of RDC/TMD, 100 patients were diagnosed with myofascial pain and 113 patients were diagnosed with disc displacement. Myofascial pain was the most common diagnosis among women; disc displacement with reduction (DDwR) was the most common diagnosis in men. Self-reported bruxism was reported by 59% of the patients. The amount of maximal mouth opening showed a statistically significant difference among patients with different clinical diagnoses and also between males and females (P<0.05). The mean visual analog scale (VAS) score was 4.9±2.4 in all diagnostic subgroups, and pain severity was higher in female patients but not significantly (P>0.05). Conclusion: Demographic characteristics of patients with TMD presenting to a dental school clinic in Ankara, Turkey were similar to those reported in the literature. A thorough anamnesis can provide more detailed information about parafunctional activity and sociodemographic factors and enhance accurate diagnosis.

European Oral Research, Jan 23, 2019

The effect of Hypericum Perforatum on wound healing of oral mucosa in diabetic rats Purpose This ... more The effect of Hypericum Perforatum on wound healing of oral mucosa in diabetic rats Purpose This study aims to investigate the histopathological and biochemical effects of the topical application of Hypericum perforatum on the healing of surgical wounds created in the oral mucosa of rats with experimentally induced diabetes mellitus. Materials and methods The study was carried out on 48 adult male Wistar albino rats. The animals were divided into two main groups as control and study groups. Two main groups were divided into three subgroups according to the sacrification days. All rats were given streptozotocin 60 mg/kg, after 72 hours, and those having blood glucose levels above 200 mg/dL were included in the study. Mucosal defects were created in the palatal area of the rats. H. perforatum oil was applied topically twice a day to the wounds of the rats in the study group. Animal were sacrificed on the 3 rd , 7 th and 10 th days and samples taken from the palatal wounds were examined histologically and biochemically. Results On the 7 th day, ulceration, necrosis, epithelialization, polymorphonuclear leucocytes and hydroxyproline variables showed statistically significant differences (p<0.05). Ulceration, necrosis and polymorphonuclear leukocytes values were higher in the control group, whereas epithelialization and hydroxyproline values were found to be higher in the H. perforatum group. Among 10 th-day groups, there was only a statistically significant difference between the values of hydroxyproline, whereas H. perforatum-treated group showed high hydroxyproline levels (p<0.05). Conclusion Topically applied H. perforatum did not create any difference on the 3 rd day, but it has positively affected the wound healing on the 7 th and 10 th days in diabetic rats.

DergiPark (Istanbul University), Nov 2, 2014

DergiPark (Istanbul University), 2001

ADO Klinik Bilimler Dergisi

Stres çok genel olarak kişinin, kendisine dayatılan taleplerin kendi uyum sağlama yeteneklerinin ... more Stres çok genel olarak kişinin, kendisine dayatılan taleplerin kendi uyum sağlama yeteneklerinin sınırlarını aştığını hissettiği durumları ifade eder. Stres, başta morbidite ve mortaliteye neden olan hastalıklar da dahil olmak üzere, hastalıkların %75-90'ının ortak risk faktörüdür. Stresin kardiyovasküler hastalıklar, HIV/AIDS, klinik depresyon ve kanser üzerindeki etkileri bilinmektedir. Temporomandibuler bozuklukların etiyolojisi komplekstir ve pek çok faktör bir arada rol oynamaktadır. Biyolojik, davranışsal, çevresel, sosyal ve psikolojik faktörlerden biri veya birkaç tanesi bir arada temporomandibuler bozuklukları hazırlayan, oluşturan ve devam ettiren faktörler olarak rol oynayabilir. Temporomandibuler bozuklukların etiyolojisinde stresin rolüne ilişkin araştırmalar 1950’li yıllardan günümüze kadar ilgi konusu olmuştur. Bu derlemenin amacı temporomandibuler bozukluk stres ilişkisine genel bir bakış ve stres mekanizmasını ve temporomandibuler bozukluğa etkisini değerlendirm...

Istanbul University - DergiPark, 2001

Sağlık Bilimleri Enstitüsü, 1991

Amac: Bu calismada, bas-boyun bolgesine radyoterapi uygulanan hastalarin agiz ici muayenesinin ya... more Amac: Bu calismada, bas-boyun bolgesine radyoterapi uygulanan hastalarin agiz ici muayenesinin yapilmasi ve sik gorulen yan etkilerden olan agiz kurulugu, yutma guclugu ve beslenme durumunda olusan degisikliklerin degerlendirilmesi amaclanmaktadir. Yontem: Calismaya primer bas boyun kanseri nedeniyle radyoterapi veya kemoradyoterapi uygulamasi yapilan, cerrahi tedavi uygulanmamis 18-80 yas arasi 26 hasta dahil edilmistir. Bulgular: Tedavi baslangicinda calismaya dahil edilen hastalarin tamaminda (%100) yutkunmada gucluk ve agiz kurulugu tespit edildi, 21 tane hastada (%80.2) beslenme problemi bulunmaktaydi. Sonuc: Degisen ve gelisen tedavi secenekleri ve organ koruyucu yaklasimla sag kalimin artmasi, koruyucu onlemlerin alinmasinin, tedavi sonrasi olusan yan etkilerin ortadan kaldirilmasinin ve gerek tip gerekse dis hekimligi icin bu konuda farkindaligin gelistirilmesinin onemini daha da arttirmaktadir. Her ne kadar radyoterapi teknikleri ve teknolojisi gelisim kaydetse de calismami...

DergiPark (Istanbul University), Nov 2, 2014

Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi, 1995

Atatürk Üniversitesi Diş Hekimliği Fakültesi dergisi, 1995

Journal of Oral Rehabilitation, Jun 7, 2017

This study was conducted to evaluate whether integrating a nociceptive trigeminal inhibition-tens... more This study was conducted to evaluate whether integrating a nociceptive trigeminal inhibition-tension suppression system (NTI-tss) device with first-line therapy of myofascial pain, which includes guidance, assurance, counselling and behavioural changes, would be more effective in alleviating symptoms. This randomised controlled clinical trial included 40 patients who were clinically diagnosed with myofascial pain according to Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Patients were randomly divided into two groups: the first group comprised patients who received guidance, assurance, counselling and behavioural changes; an NTI-tss device was integrated to this protocol in the second group. Both groups exhibited reduction in pain levels and improvement of jaw function compared with baseline values, but the difference was not significant. Both groups demonstrated improvements in 6 weeks; however, the integration of NTI-tss device into the therapy protocol did not provide any additional benefit in relieving symptoms of myofascial pain.

Acta odontologica turcica, Sep 1, 2021

OBJECTIVE: The study aims to evaluate the presence of temporomandibular disorders (TMD) and their... more OBJECTIVE: The study aims to evaluate the presence of temporomandibular disorders (TMD) and their severity in asymptomatic and healthy individuals using the Fonseca anamnestic index. MATERIALS AND METHOD: A total of 135 individuals (80 females and 55 males, mean age 34.4±10.9) were involved in the study. The Fonseca anamnestic index was administered to the individuals. The data analysis was conducted by using Pearson's chi-squared test, Fisher's exact test, one-way ANOVA, and Spearman's correlation. RESULTS: TMD was detected in 63% of the individuals. Most of them (40%) had mild TMD. The difference between gender and TMD severity was statistically significant (p=0.001). Temporomandibular joint (TMJ) pain showed a statistically significant positive correlation with headache and emotional stress (r=0.312, p˂0.001; r=0.299, p˂0.001, respectively). TMJ pain showed the strongest positive correlation with clicking (r=0.443, p˂0.001). Bruxism showed positive correlations with the TMJ pain and clicking (r=0.197, p=0.022 and r= 0.221, p=0.010, respectively). CONCLUSION: The Fonseca anamnestic index is a reliable diagnostic tool that can be used to detect TMD-related symptoms and severity even in asymptomatic and healthy participants, providing rapid results in clinical practice.

Journal of Oral and Maxillofacial Surgery, Jun 1, 2001

Purpose This study was designed to investigate the efficacy of arthrocentesis on mouth opening an... more Purpose This study was designed to investigate the efficacy of arthrocentesis on mouth opening and pain in the treatment of temporomandibular joint (TMJ) internal derangement patients. Materials and Methods Fifteen males and 25 females aged between 18 and 37 years comprised the study material in the department of oral and maxillofacial surgery at Govt Dental College Srinagar (India). The patients' complaints were limited mouth opening and TMJ pain. Arthrocentesis was performed under aseptic conditions. Clinical evaluation of the patients was done before the procedure, and 1 week and 4 months post-operatively. Intensity of TMJ pain and maximal mouth opening were recorded at each follow-up visit. Results There was significant improvement in mouth opening and reduction in pain scores in the post-operative period. Conclusions Arthrocentesis is a simple and safe procedure for patients of internal derangement with closed lock for improving mouth opening and decreasing pain.

International Journal of Oral and Maxillofacial Surgery, Oct 1, 2013

DergiPark (Istanbul University), May 1, 2000

Shahid Beheshti University Dental Journal, Mar 10, 2017

Objectives: This study was undertaken to observe the frequency of different diagnostic groups for... more Objectives: This study was undertaken to observe the frequency of different diagnostic groups for temporomandibular disorders (TMDs) in patients who sought treatment for TMD in an outpatient clinic of a dental school. Methods: Files of patients who received a diagnosis of TMD in a period of 24 months were evaluated. Clinical and demographic data extracted from 213 patient files meeting the inclusion criteria were analyzed. Results: According to the classification of RDC/TMD, 100 patients were diagnosed with myofascial pain and 113 patients were diagnosed with disc displacement. Myofascial pain was the most common diagnosis among women; disc displacement with reduction (DDwR) was the most common diagnosis in men. Self-reported bruxism was reported by 59% of the patients. The amount of maximal mouth opening showed a statistically significant difference among patients with different clinical diagnoses and also between males and females (P<0.05). The mean visual analog scale (VAS) score was 4.9±2.4 in all diagnostic subgroups, and pain severity was higher in female patients but not significantly (P>0.05). Conclusion: Demographic characteristics of patients with TMD presenting to a dental school clinic in Ankara, Turkey were similar to those reported in the literature. A thorough anamnesis can provide more detailed information about parafunctional activity and sociodemographic factors and enhance accurate diagnosis.

European Oral Research, Jan 23, 2019

The effect of Hypericum Perforatum on wound healing of oral mucosa in diabetic rats Purpose This ... more The effect of Hypericum Perforatum on wound healing of oral mucosa in diabetic rats Purpose This study aims to investigate the histopathological and biochemical effects of the topical application of Hypericum perforatum on the healing of surgical wounds created in the oral mucosa of rats with experimentally induced diabetes mellitus. Materials and methods The study was carried out on 48 adult male Wistar albino rats. The animals were divided into two main groups as control and study groups. Two main groups were divided into three subgroups according to the sacrification days. All rats were given streptozotocin 60 mg/kg, after 72 hours, and those having blood glucose levels above 200 mg/dL were included in the study. Mucosal defects were created in the palatal area of the rats. H. perforatum oil was applied topically twice a day to the wounds of the rats in the study group. Animal were sacrificed on the 3 rd , 7 th and 10 th days and samples taken from the palatal wounds were examined histologically and biochemically. Results On the 7 th day, ulceration, necrosis, epithelialization, polymorphonuclear leucocytes and hydroxyproline variables showed statistically significant differences (p<0.05). Ulceration, necrosis and polymorphonuclear leukocytes values were higher in the control group, whereas epithelialization and hydroxyproline values were found to be higher in the H. perforatum group. Among 10 th-day groups, there was only a statistically significant difference between the values of hydroxyproline, whereas H. perforatum-treated group showed high hydroxyproline levels (p<0.05). Conclusion Topically applied H. perforatum did not create any difference on the 3 rd day, but it has positively affected the wound healing on the 7 th and 10 th days in diabetic rats.

DergiPark (Istanbul University), Nov 2, 2014

DergiPark (Istanbul University), 2001

ADO Klinik Bilimler Dergisi

Stres çok genel olarak kişinin, kendisine dayatılan taleplerin kendi uyum sağlama yeteneklerinin ... more Stres çok genel olarak kişinin, kendisine dayatılan taleplerin kendi uyum sağlama yeteneklerinin sınırlarını aştığını hissettiği durumları ifade eder. Stres, başta morbidite ve mortaliteye neden olan hastalıklar da dahil olmak üzere, hastalıkların %75-90'ının ortak risk faktörüdür. Stresin kardiyovasküler hastalıklar, HIV/AIDS, klinik depresyon ve kanser üzerindeki etkileri bilinmektedir. Temporomandibuler bozuklukların etiyolojisi komplekstir ve pek çok faktör bir arada rol oynamaktadır. Biyolojik, davranışsal, çevresel, sosyal ve psikolojik faktörlerden biri veya birkaç tanesi bir arada temporomandibuler bozuklukları hazırlayan, oluşturan ve devam ettiren faktörler olarak rol oynayabilir. Temporomandibuler bozuklukların etiyolojisinde stresin rolüne ilişkin araştırmalar 1950’li yıllardan günümüze kadar ilgi konusu olmuştur. Bu derlemenin amacı temporomandibuler bozukluk stres ilişkisine genel bir bakış ve stres mekanizmasını ve temporomandibuler bozukluğa etkisini değerlendirm...

Istanbul University - DergiPark, 2001

Sağlık Bilimleri Enstitüsü, 1991

Amac: Bu calismada, bas-boyun bolgesine radyoterapi uygulanan hastalarin agiz ici muayenesinin ya... more Amac: Bu calismada, bas-boyun bolgesine radyoterapi uygulanan hastalarin agiz ici muayenesinin yapilmasi ve sik gorulen yan etkilerden olan agiz kurulugu, yutma guclugu ve beslenme durumunda olusan degisikliklerin degerlendirilmesi amaclanmaktadir. Yontem: Calismaya primer bas boyun kanseri nedeniyle radyoterapi veya kemoradyoterapi uygulamasi yapilan, cerrahi tedavi uygulanmamis 18-80 yas arasi 26 hasta dahil edilmistir. Bulgular: Tedavi baslangicinda calismaya dahil edilen hastalarin tamaminda (%100) yutkunmada gucluk ve agiz kurulugu tespit edildi, 21 tane hastada (%80.2) beslenme problemi bulunmaktaydi. Sonuc: Degisen ve gelisen tedavi secenekleri ve organ koruyucu yaklasimla sag kalimin artmasi, koruyucu onlemlerin alinmasinin, tedavi sonrasi olusan yan etkilerin ortadan kaldirilmasinin ve gerek tip gerekse dis hekimligi icin bu konuda farkindaligin gelistirilmesinin onemini daha da arttirmaktadir. Her ne kadar radyoterapi teknikleri ve teknolojisi gelisim kaydetse de calismami...