mehwish jabeen | Govt. Postgraduate College Samanabd faisalabad (original) (raw)

mehwish jabeen

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Papers by mehwish jabeen

Research paper thumbnail of Towards secure wirelessMAN: Revisiting and evaluating authentication in WiMAX

International Conference on Computer Networks and Information Technology, 2011

Research paper thumbnail of Improved Secure Network Authentication Protocol (ISNAP) for IEEE 802.16

2009 International Conference on Information and Communication Technologies, 2009

Research paper thumbnail of Synthesis and Characterization of Novel n-9 Fatty Acid Conjugates Possessing Antineoplastic Properties

Lipids, 2012

The present study enumerates the synthesis, spectroscopic characterization, and evaluation of ant... more The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphenol (propofol) to the terminal carboxyl group of n-9 fatty acid. The synthesized propofol-n-9 conjugates having greater lipophilic character were tested initially for cytotoxicity in-vitro. The conjugates showed specific growth inhibition of cancer cell lines whereas no effect was observed in normal cells. In general, pronounced growth inhibition was found against the human skin malignant melanoma cell line (SK-MEL-1). The anticancer potential was also determined by testing the effect of these conjugates on cell migration, cell adhesion and induction of apoptosis in SK-MEL-1 cancer cells. Propofol-OLA conjugates significantly induced apoptosis in contrast to propofol-RC...

Research paper thumbnail of Towards secure wirelessMAN: Revisiting and evaluating authentication in WiMAX

International Conference on Computer Networks and Information Technology, 2011

Research paper thumbnail of Improved Secure Network Authentication Protocol (ISNAP) for IEEE 802.16

2009 International Conference on Information and Communication Technologies, 2009

Research paper thumbnail of Synthesis and Characterization of Novel n-9 Fatty Acid Conjugates Possessing Antineoplastic Properties

Lipids, 2012

The present study enumerates the synthesis, spectroscopic characterization, and evaluation of ant... more The present study enumerates the synthesis, spectroscopic characterization, and evaluation of anticancer potential of esters of two n-9 fatty acids viz., oleic acid (OLA) and ricinoleic acid (RCA) with 2,4- or 2,6-diisopropylphenol. The synthesis strategy involved esterification of the hydroxyl group of diisopropylphenol (propofol) to the terminal carboxyl group of n-9 fatty acid. The synthesized propofol-n-9 conjugates having greater lipophilic character were tested initially for cytotoxicity in-vitro. The conjugates showed specific growth inhibition of cancer cell lines whereas no effect was observed in normal cells. In general, pronounced growth inhibition was found against the human skin malignant melanoma cell line (SK-MEL-1). The anticancer potential was also determined by testing the effect of these conjugates on cell migration, cell adhesion and induction of apoptosis in SK-MEL-1 cancer cells. Propofol-OLA conjugates significantly induced apoptosis in contrast to propofol-RC...

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