GitHub - Codezy99/cliProfiler (original) (raw)

cliProfiler

Author: You Zhou, Kathi Zarnack

Introduction

Cross-linking immunoprecipitation (CLIP) is a technique that combines UV cross-linking and immunoprecipitation to analyse protein-RNA interactions or to pinpoint RNA modifications (e.g. m6A). CLIP-based methods, such as iCLIP and eCLIP, allow precise mapping of RNA modification sites or RNA-binding protein (RBP) binding sites on a genome-wide scale. These techniques help us to unravel post-transcriptional regulatory networks. In order to make the visualization of CLIP data easier, we develop r Biocpkg("cliProfiler") package. Ther Biocpkg("cliProfiler") includes seven functions which allow users easily make different profile plots.

The r Biocpkg("cliProfiler") package is available athttps://bioconductor.org and can be installed via BiocManager::install:

if (!require("BiocManager"))
    install.packages("BiocManager")
BiocManager::install("cliProfiler")

A package only needs to be installed once. Load the package into an R session with

How to use it

Documentation (vignette and user manual) is available at the cliProfilerBioconductor landing page at http://bioconductor.org/packages/cliProfiler.