Shengquan Ding | Griffith University (original) (raw)
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Graphene Tourmaline Composite Micropowder (hereinafter referred to as GTCM) modified asphalt was ... more Graphene Tourmaline Composite Micropowder (hereinafter referred to as GTCM) modified asphalt was prepared by the ball milling method. The effects of different temperatures and different frequencies on the high-temperature performance of composite-modified asphalt were evaluated by dynamic shear rheological test, and the viscoelastic properties of composite-modified asphalt under different stresses and different temperatures were analyzed. The low-temperature rheological properties of GTCM-modified asphalt were analyzed by bending beam rheological test, and its mechanism was analyzed by Fourier transform infrared spectroscopy (FTIR) test. The results show that the temperature sensitivity and anti-aging resistance of GTCM-modified asphalt are significantly higher than that of tourmaline-modified asphalt. The improvement effect gradually increases with the increase in graphene powder content, and its addition does not change the viscoelastic properties of asphalt. The complex shear mod...
Materials
In order to obtain the optimal electrode layout and ice melting effect of cast conductive asphalt... more In order to obtain the optimal electrode layout and ice melting effect of cast conductive asphalt concrete steel bridge deck pavement, firstly, pouring conductive asphalt concrete was prepared; secondly, different electrode materials and layout methods were selected to test the heating rate of the specimen from start to 120 min, and the electrode materials and layout methods were optimized. Then, the finite element analysis software ANSYS was used to build the model for heating and ice melting simulation, and the indoor test was used to further verify the ice melting effect of the cast conductive asphalt coagulation with or without the insulation layer. Finally, the thermal-structural coupling analysis of cast conductive asphalt concrete steel bridge deck pavement was carried out using ANSYS finite element software. The results showed that the stainless steel electrode material had the best heating effect, and the electrode thickness in the range of 0.1~3 mm had no effect on the hea...
Biochemical and Biophysical Research Communications, 2014
In this study, we explored the cytoprotective potential of silibinin against oxygen-glucose depri... more In this study, we explored the cytoprotective potential of silibinin against oxygen-glucose deprivation (OGD)-induced neuronal cell damages, and studied underling mechanisms. In vitro model of ischemic stroke was created by keeping neuronal cells (SH-SY5Y cells and primary mouse cortical neurons) in an OGD condition followed by re-oxygenation. Pre-treatment of silibinin significantly inhibited OGD/re-oxygenation-induced necrosis and apoptosis of neuronal cells. OGD/re-oxygenation-induced reactive oxygen species (ROS) production and mitochondrial membrane potential (MMP) reduction were also inhibited by silibinin. At the molecular level, silibinin treatment in SH-SY5Y cells and primary cortical neurons led to significant AMP-activated protein kinase (AMPK) signaling activation, detected by phosphorylations of AMPKα1, its upstream kinase liver kinase B1 (LKB1) and the downstream target acetyl-CoA Carboxylase (ACC). Pharmacological inhibition or genetic depletion of AMPK alleviated the neuroprotective ability of silibinin against OGD/re-oxygenation. Further, ROS scavenging ability by silibinin was abolished with AMPK inhibition or silencing. While A-769662, the AMPK activator, mimicked silibinin actions and suppressed ROS production and neuronal cell death following OGD/re-oxygenation. Together, these results show that silibinin-mediated neuroprotection requires activation of AMPK signaling.
Coatings
Graphene Tourmaline Composite Micropowder (hereinafter referred to as GTCM) modified asphalt was ... more Graphene Tourmaline Composite Micropowder (hereinafter referred to as GTCM) modified asphalt was prepared by the ball milling method. The effects of different temperatures and different frequencies on the high-temperature performance of composite-modified asphalt were evaluated by dynamic shear rheological test, and the viscoelastic properties of composite-modified asphalt under different stresses and different temperatures were analyzed. The low-temperature rheological properties of GTCM-modified asphalt were analyzed by bending beam rheological test, and its mechanism was analyzed by Fourier transform infrared spectroscopy (FTIR) test. The results show that the temperature sensitivity and anti-aging resistance of GTCM-modified asphalt are significantly higher than that of tourmaline-modified asphalt. The improvement effect gradually increases with the increase in graphene powder content, and its addition does not change the viscoelastic properties of asphalt. The complex shear mod...
Materials
In order to obtain the optimal electrode layout and ice melting effect of cast conductive asphalt... more In order to obtain the optimal electrode layout and ice melting effect of cast conductive asphalt concrete steel bridge deck pavement, firstly, pouring conductive asphalt concrete was prepared; secondly, different electrode materials and layout methods were selected to test the heating rate of the specimen from start to 120 min, and the electrode materials and layout methods were optimized. Then, the finite element analysis software ANSYS was used to build the model for heating and ice melting simulation, and the indoor test was used to further verify the ice melting effect of the cast conductive asphalt coagulation with or without the insulation layer. Finally, the thermal-structural coupling analysis of cast conductive asphalt concrete steel bridge deck pavement was carried out using ANSYS finite element software. The results showed that the stainless steel electrode material had the best heating effect, and the electrode thickness in the range of 0.1~3 mm had no effect on the hea...
Biochemical and Biophysical Research Communications, 2014
In this study, we explored the cytoprotective potential of silibinin against oxygen-glucose depri... more In this study, we explored the cytoprotective potential of silibinin against oxygen-glucose deprivation (OGD)-induced neuronal cell damages, and studied underling mechanisms. In vitro model of ischemic stroke was created by keeping neuronal cells (SH-SY5Y cells and primary mouse cortical neurons) in an OGD condition followed by re-oxygenation. Pre-treatment of silibinin significantly inhibited OGD/re-oxygenation-induced necrosis and apoptosis of neuronal cells. OGD/re-oxygenation-induced reactive oxygen species (ROS) production and mitochondrial membrane potential (MMP) reduction were also inhibited by silibinin. At the molecular level, silibinin treatment in SH-SY5Y cells and primary cortical neurons led to significant AMP-activated protein kinase (AMPK) signaling activation, detected by phosphorylations of AMPKα1, its upstream kinase liver kinase B1 (LKB1) and the downstream target acetyl-CoA Carboxylase (ACC). Pharmacological inhibition or genetic depletion of AMPK alleviated the neuroprotective ability of silibinin against OGD/re-oxygenation. Further, ROS scavenging ability by silibinin was abolished with AMPK inhibition or silencing. While A-769662, the AMPK activator, mimicked silibinin actions and suppressed ROS production and neuronal cell death following OGD/re-oxygenation. Together, these results show that silibinin-mediated neuroprotection requires activation of AMPK signaling.