Jaswinder Singh | PTU JALANDRER PUNJAB (original) (raw)

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Papers by Jaswinder Singh

Research paper thumbnail of Jerusalem artichoke: An emerging crop for bioenergy and bioproducts in north america

Research paper thumbnail of Genome-Wide Association Study Reveals Novel Genetic Determinants of DNA Repair Capacity in Lung Cancer

Cancer Research, 2012

Suboptimal cellular DNA repair capacity (DRC) has been shown to be associated with enhanced cance... more Suboptimal cellular DNA repair capacity (DRC) has been shown to be associated with enhanced cancer risk, but genetic variants affecting the DRC phenotype have not been comprehensively investigated. In this study, with the available DRC phenotype data, we analyzed correlations between the DRC phenotype and genotypes detected by the Illumina 317K platform in 1,774 individuals of European ancestry from a Texas lung cancer genome-wide association study. The discovery phase was followed by a replication in an independent set of 1,374 cases and controls of European ancestry. We applied a generalized linear model with single nucleotide polymorphisms as predictors and DRC (a continuous variable) as the outcome. Covariates of age, sex, pack-years of smoking, DRC assay-related variables, and case–control status of the study participants were adjusted in the model. We validated that reduced DRC was associated with an increased risk of lung cancer in both independent datasets. Several suggestiv...

Research paper thumbnail of Computer graphics and applications

Information Processing & Management, 1986

Research paper thumbnail of Standard -6 th

Research paper thumbnail of Jerusalem artichoke: An emerging crop for bioenergy and bioproducts in north america

Research paper thumbnail of Genome-Wide Association Study Reveals Novel Genetic Determinants of DNA Repair Capacity in Lung Cancer

Cancer Research, 2012

Suboptimal cellular DNA repair capacity (DRC) has been shown to be associated with enhanced cance... more Suboptimal cellular DNA repair capacity (DRC) has been shown to be associated with enhanced cancer risk, but genetic variants affecting the DRC phenotype have not been comprehensively investigated. In this study, with the available DRC phenotype data, we analyzed correlations between the DRC phenotype and genotypes detected by the Illumina 317K platform in 1,774 individuals of European ancestry from a Texas lung cancer genome-wide association study. The discovery phase was followed by a replication in an independent set of 1,374 cases and controls of European ancestry. We applied a generalized linear model with single nucleotide polymorphisms as predictors and DRC (a continuous variable) as the outcome. Covariates of age, sex, pack-years of smoking, DRC assay-related variables, and case–control status of the study participants were adjusted in the model. We validated that reduced DRC was associated with an increased risk of lung cancer in both independent datasets. Several suggestiv...

Research paper thumbnail of Computer graphics and applications

Information Processing & Management, 1986

Research paper thumbnail of Standard -6 th

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