Ozlem Aki | Hacettepe University (original) (raw)

Papers by Ozlem Aki

Research Square (Research Square), May 19, 2023

Objectives: This study examined the relationship between comorbidity indices and comprehensive ge... more Objectives: This study examined the relationship between comorbidity indices and comprehensive geriatric assessment including psychologic, social frailty, and geropsychiatric evaluation. Methods: A cross-sectional analysis was conducted with 136 community-dwelling older adults. The relationship of 4 comorbidity indices (CIRS-G, ACCI, GIC, ICED) with 3 different frailty scales (FRAIL, CFS, TFI) was examined. Results: Overall, 58.8% of the participants were living with frailty according to the TFI, 47.7% of them living with psychological frailty, and 28.6% of them living with social frailty. There were signi cant and moderate correlations between CIRS-G and FRAIL, CFS and TFI total scores, TFI-Psychological scores and TFI-Social scores (respectively; p<0.001, r = 0.530; p<0.001, r = 0.471; p<0.001, r = 0.535; p<0.001, r = 0.402; p= 0.016 r = 0.206). AUC for CIRS-G was calculated as 0.746 among comorbidity indices in predicting the presence of frailty according to the TFI (p<0.001, 95%CI [0.66-0.82]), for ACCI AUC was 0.631 (p=0.01, 95%CI [0.53-0.72]), for GIC AUC was 0.595 (p=0.059, 95%CI [0.49-0.69]), for ICED AUC was 0.666 (p=0.001, 95%CI [0.57-0.75]). The CIRS-G index was found to be superior to other indices in predicting the presence of frailty of comorbidity indices, and only GIC scores showed signi cant results in predicting mortality. However, it would be incomplete to conclude with a comorbidity index alone by ignoring the results of comprehensive geriatric assessment. Aim: To evaluate the relationship between comorbidity indices and comprehensive geriatric assessment including frailty. Findings: The CIRS-G index was found to be superior to other indices in predicting the presence of frailty of comorbidity indices, and only GIC scores showed signi cant results in predicting mortality Message: Although CIRS-G seems to be the index most associated with comprehensive geriatric assessment, including psychological and social frailty, no single comorbidity index should be recommended for predicting clinical outcomes in older adults.

Nöropsikiyatri arşivi, Mar 27, 2015

The number of women with careers in medicine and with academic positions at medical schools has i... more The number of women with careers in medicine and with academic positions at medical schools has increased substantially since the 1980s; however, women remain underrepresented in medical academia, which may be because of the fewer research publications authored by women. This study aimed to determine the gender distribution among Turkish authors of psychiatry articles published in international scientific journals during a 30-year period.

geriatri.dergisi.org

With the considerable growth in the elderly population in the last years, health and care needs o... more With the considerable growth in the elderly population in the last years, health and care needs of the elderly became more important. The health problems, physical difficulties and losses connected with the aging process increased the prevalence of psychiatric diseases ...

Turkish Journal of Geriatrics-Turk Geriatri Dergisi, Sep 30, 2020

The new type of corona virus (SARS-Cov 2) pandemic, which broke out in Wuhan province of China in... more The new type of corona virus (SARS-Cov 2) pandemic, which broke out in Wuhan province of China in December 2019, has spread rapidly in a short time, affected and is still affecting millions of people all over the world. Numerous measures have been taken to prevent the spread of the outbreak, in particular "maintaining social distance". Elderly individuals are vulnerable to COVID-19 due to the aging of their immune systems and concomitant chronic diseases; morbidity and mortality are rather high in this age group, so prevention measures are even of greater importance in older individuals. However, both the pandemic and the infection control measures taken for the pandemic negatively affect the mental health of elderly individuals as well as their physical health. In this review study, it was aimed to examine briefly the effects of pandemics on mental health of the society, to review the studies investigating the effects of outbreaks on the mental health of the elderly, and to make inferences for the future.

Turkish Journal of Geriatrics-Turk Geriatri Dergisi, Dec 31, 2022

Introduction: Restrictive measures were taken to protect people aged 65 years and older during co... more Introduction: Restrictive measures were taken to protect people aged 65 years and older during coronavirus pandemic; however, these measures negatively affected their physical and mental health. Ageist attitudes and age discrimination have also become evident during the pandemic. This study aimed to evaluate the relationship between perceived ageism, sense of autonomy, perceptions of curfews, and anxiety and depression levels in older psychiatric patients who comprised a vulnerable and disadvantaged group during the pandemic. Materials and Methods: In this cross-sectional study, 171 participants older than 65 years, followed up at Hacettepe University Psychiatry outpatient clinic between December 2019 and February 2020, were interviewed via phone using a survey on sociodemographic characteristics, measures of perceived ageism and autonomy, Generalized Anxiety Disorder Scale, and Geriatric Depression Scale-Short Form. Results: Of 171 total participants, 57 (34.8%) reported an increase in perceived ageism during the pandemic. Almost one-third of the participants found the curfew decisions for the elderly to be unsuitable. Participants with higher education levels and those who found curfews for the elderly inappropriate showed a greater increase in perceived ageism scores (p<0.001). Additionally, perceived ageism scores were significantly correlated with depression and anxiety (p<0.001). Anxiety and depression scores were significantly lower among participants who reported more autonomy in their lives (p<0.05). Conclusion: During pandemic, state and health authorities should consider the needs of vulnerable groups, such as older individuals and psychiatric patients, when making plans, and ensure that these groups are minimally affected by the disease, restrictive measures, and ageist attitudes.

The Turkish Journal of Geriatrics

Purpose The study aimed to investigate the problematic eating patterns, and understand their rela... more Purpose The study aimed to investigate the problematic eating patterns, and understand their relationship to some psychological constructs including stress intolerance, coping mechanisms and impulsivity; and psychiatric symptoms among a group of bariatric surgery candidates. Methods The bariatric candidates were evaluated by psychiatric interview and standard scales assessing maladaptive eating behaviors (Eating Attitudes Test (EAT), Bulimia Investigatory Test-Edinburgh (BITE), Dutch Eating Behavior Questionnaire(DEBQ)), depression (Beck Depression Inventory (BDI)), psychiatric symptoms (Brief Symptom Inventory (BSI)), and psychological constructs (Distress Intolerance Index (DSI), Coping Styles Scale (CSS), UPPS Impulsive Behavior Scale(UPPS)). Results More than half (57.8%) of the sample had maladaptive eating behaviors, and 23.6% had binge eating behavior. Depression and anxiety were found to predict EAT, BITE and DEBQ emotional and external eating sub-scale scores; and distress ...

European Psychiatry, Apr 1, 2017

TURKISH JOURNAL OF MEDICAL SCIENCES, 2020

Background/Aim: The patients with cystic fibrosis (CF) are living longer compared to the past, bu... more Background/Aim: The patients with cystic fibrosis (CF) are living longer compared to the past, but respiratory failure is still the most common cause of mortality. The aim of this study is to investigate factors associated with severe lung disease in a cohort of adult patients with CF. Materials and methods: Demographic data, clinical and laboratory findings of the patients aged 18 years and more were collected and the patients were grouped according to forced expiratory volume in 1 s (FEV 1) as severe group: <40% and nonsevere ≥40%. Associations were investigated between groups and clinical outcomes. Results: A total of 76 patients were enrolled in the study. The mean age was 24.5 ± 5.25 years and 36 (47.4%) patients were female. In the severe group; the mean age was higher (27.1 ± 6.0 vs 23.6 ± 4.7, P = 0.013), the median Chrispin-Norman score of severe lung disease group was higher (14 (6-22) vs 5.5 (0-20), P < 0.001), hospitalization at least once in a year for intravenous antibiotic was more common (12/18 (66%) vs 19/58 (32%), P = 0.014). There was a positive correlation between body mass index (BMI) and lung function, indicating that lower nutritional status was related to lower FEV 1 , r 2 = 0.21, P < 0.001. The median FEV 1 % was lower in patients with CF-related diabetes (38 (14-95) vs 66 (13-121), P = 0.042). Dornase alpha use and physiotherapy rate were higher in severe lung disease group (P = 0.008 and P < 0.001, respectively). Conclusion: Lower BMI, older age, presence of CF-related diabetes, higher radiologic scores, use of dornase alpha and physiotherapy and higher hospitalization rate for intravenous antibiotic therapy are significantly associated with severe lung disease.

Turkish Journal of Psychiatry, 2020

Sa ay yı ı E Ed di it tö ör rü ün nd de en n Sibel ÇAKIR Işın BARAL KULAKSIZOĞLU 1 M Ma aj jo or ... more Sa ay yı ı E Ed di it tö ör rü ün nd de en n Sibel ÇAKIR Işın BARAL KULAKSIZOĞLU 1 M Ma aj jo or r v ve e H Ha afi fif f N Nö ör ro ok ko og gn ni it ti if f B Bo oz zu uk kl lu uk kl la ar r: : A Al lz zh he ei im me er r H Ha as st ta al lı ığ ğı ı Major and Mild Neurocognitive Disorders: Alzheimer Disease Özlem ERDEN AKİ 9 M Ma aj jo or r v ve e M Mi in no or r N Nö ör ro ok ko og gn ni it ti if f B Bo oz zu uk kl lu uk kl la ar r: : F Fr ro on nt to ot te em mp po or ra al l D De em ma an ns s Major and Minor Neurocognitive Disorders: Frontotemporal Dementia

Archives of Neuropsychiatry, 2021

Introduction: Informed consent is an indispensable condition of the clinical practice for the pro... more Introduction: Informed consent is an indispensable condition of the clinical practice for the provision of health care. The main objective of this study is to translate the MacArthur competence assessment tool for treatment (MacCAT-T) into Turkish and evaluate the validity and reliability of the Turkish version in schizophrenia patients and healthy control subjects. Methods: In this cross-sectional study, 30 hospitalized schizophrenia patients and 25 healthy subjects were assessed with MacCAT-T, Mental Competence Evaluation Form for Assessment of Competency (MCEF), Positive and Negative Syndrome Scale, Beck Depression Inventory, Mini Mental State Examination, Wechsler Adult Intelligence Scale (WAIS)-Similarities subtest and the Schedule for Assessing the Three Components of Insight. Psychometric properties of MacCAT-T were examined by intra-class correlation coefficients and Cronbach's alpha values. Results: Intra-class correlations ranged between 0.83 and 0.99 for four subscales of the tool. Cronbach alpha value of MacCAT-T was found 0.89. Severity of psychopathology and indices of insight were found to be negatively correlated with the subscales of the tool. WAIS-Similarities subtest scores were found to be positively correlated with understanding and reasoning subscales of MacCAT-T. Conclusion: The Turkish version of MacCAT-T is a valid and reliable instrument for Turkish patients. The severity of psychopathology, insight and executive functions were shown to be significantly related to the decision making capacity in patients with schizophrenia.

Turkish Journal of Psychiatry, 2021

A Severe Neuroleptic Malignant Syndrome Treated with Daily Electroconvulsive Therapy: A Case Repo... more A Severe Neuroleptic Malignant Syndrome Treated with Daily Electroconvulsive Therapy: A Case Report Neuroleptic malignant syndrome (NMS) is a rare but life-threatening condition caused by dopamine modulating medications, particularly antipsychotics. First-line treatments of neuroleptic malignant syndrome are supportive care, discontinuation of the offending agent and pharmacotherapy. In drug-resistant and severe situations, electroconvulsive therapy (ECT) is recommended as well. In this paper we present a 23-year old male with bipolar disorder who was treated with multiple injections of zuclopenthixol long acting and depot forms for a recent manic episode and developed NMS. The patient was transferred to an intensive care unit, medical management was initiated including benzodiazepines, bromocriptine and dantrolene. Due to the inadequate response after several days, ECT (bitemporal electrode placement, briefpulse, on a daily basis) was initiated. After 17 sessions, NMS relieved and there was no need for maintenance ECT. The patient is under follow-up care for 3 years with no cognitive and physical sequela.

The International Journal of Psychiatry in Medicine, 2013

Objective: Postpartum depression (PPD) is an important health issue that affects not only mothers... more Objective: Postpartum depression (PPD) is an important health issue that affects not only mothers, but also entire families. Postpartum follow-up should address emotional and psychological issues, as well as physical issues, especially in those at risk. This study aimed to determine the incidence of PPD and the associated risk factors in a group of new mothers undergoing routine follow-up at an urban maternity clinic. Methods: This is a cross-sectional study investigating the relationship between PPD and various factors. A total of 187 women that presented to a university hospital for routine postpartum follow-up 4–6 weeks post delivery were recruited consecutively. The mothers were administered a sociodemographic form that included questions about the known risk factors (sociodemographic and sociocultural factors, and mother-related, pregnancy-related, and child-related factors) and the Edinburgh Postnatal Depression Scale (EPDS). Results: The incidence of PPD based on EPDS scores ...

Dusunen Adam: The Journal of Psychiatry and Neurological Sciences, 2018

Does a history of surgically repaired intracranial aneurysm interfere with electroconvulsive ther... more Does a history of surgically repaired intracranial aneurysm interfere with electroconvulsive therapy? Electroconvulsive therapy (ECT) is a comparably safe treatment option frequently administered for treatment-refractory mental disorders. It has no absolute contraindication; however, careful attention should be given when ECT is applied to patients with comorbid conditions. Intracranial aneurysms are among the comorbidities that increase certain risks associated with ECT. Increase in cerebral blood flow during ECT may be associated with increased risk of rupture of an aneurysm and bleeding from vascular malformation. In the literature, there is a limited number of case reports on ECT administration in patients with surgically repaired cerebral aneurysm. In this case report, application of ECT in a 53-year-old female patient diagnosed with treatment-refractory major depressive disorder and with a history of surgical repair for intracranial aneurysm is presented. In addition, special considerations and precautions about ECT application for patients with repaired intracranial aneurysms are reviewed.

Turkish Journal of Psychiatry

Bu çalışmada, belli bir sürede ve belli bir kategoride sözcük üretilmesi esasına dayalı Sözel Akı... more Bu çalışmada, belli bir sürede ve belli bir kategoride sözcük üretilmesi esasına dayalı Sözel Akıcılık Testi için norm verilerinin elde edilmesi ve yaş, cinsiyet ve eğitim düzeyinin anadili Türkçe olan bireylerde sözel akıcılık üzerine etkisinin incelenmesi amaçlanmıştır. Yöntem: Öncelikle fonemik akıcılık testi için farklı zorluk derecelerinde 3 harf belirlenmesi amacıyla bir pilot çalışma yürütülmüştür. Semantik akıcılık testi için insan isimleri ve hayvan isimleri seçilmiş, dönüşümlü semantik akıcılık testi için "insan ismi-hayvan ismi" olacak şekilde seçim yapılmıştır. Toplam 415 kişi (208 erkek ve 207 kadın) çalışmaya alınmış, yaş ve eğitim düzeyine göre tabakalandırılmıştır. Çeşitli türde hataların analizi de yapılmıştır. Bulgular: Eğitim düzeyinin tüm sözel akıcılık türleri üzerinde etkisi olduğu saptanmıştır, eğitim düzeyi yüksek olan bireyler eğitim düzeyi düşük olanlardan anlamlı olarak daha fazla sayıda sözcük üretmiştir. Yaş ve cinsiyetin fonemik sözel akıcılık üzerinde etkisinin olmadığı bulunmuştur. Cinsiyet sadece insan ismi üretme görevinde anlamlı bir fark yaratmış, kadınların daha fazla sayıda insan ismi ürettiği saptanmıştır. Genç yaş grupları daha fazla sayıda insan ismi ve dönüşümlü insan ismi-hayvan ismi üretmişlerdir. Sonuç: Bu çalışmada yaş, cinsiyet ve eğitim düzeyi değişkenlerinin sözel akıcılık üzerindeki etkileri daha önce yapılan pek çok çalışmanın sonuçlarıyla uyumludur. Çalışmada hata analizi de yapılmıştır. Sonuçlar literatür ışığında sunulmuş ve tartışılmıştır.

Objective: To compare coping mechanisms and appraisal of coping skills at various stages of remis... more Objective: To compare coping mechanisms and appraisal of coping skills at various stages of remission in patients with alcohol dependence.Method: This was a cross sectional study comparing the results of 3 groups including group 1- patients with alcohol dependence and, group 2-patients with alcohol dependence and in remission for at least 1 year and group 3 – a control group consisting of healthy individuals without any history of substance use except smoking. Hamilton Depression Scale, Coping with Stress Scale, Problem Solving Inventory, Rosenbaum’s Learned Resourcefulness Inventory, Rotter’s Locus of Control Scale, Beck Depression Scale, Beck Hopelessness Scale, State- Trait Anxiety Inventory and Minnesota Multiphasic Personality Inventory (MMPI) were completed for all subjects.Results: The control group and persons with at least one year of remission used adaptive coping mechanisms more frequently. Factors associated with the degree of alcohol dependence, such ase age at the star...