Manish Raturi | HIHT University, Dehradun (original) (raw)

Papers by Manish Raturi

Research paper thumbnail of Establishing a regional rare blood donor registry in Uttarakhand, India

Global journal of transfusion medicine, Dec 31, 2022

Research paper thumbnail of The Quandary of a Healthy (Child) Sibling Stem Cell Donor

Indian Journal of Medical and Paediatric Oncology, Jul 1, 2020

Research paper thumbnail of Imperishable blood stains splattered for Humanity: Reappraising the Shroud of Turin

Transfusion Clinique et Biologique

Research paper thumbnail of Reporting an immune-mediated neonatal hyperbilirubinemia following Rh (D) isoimmunization in an Indian term newborn bearing A<sub>MFA</sub> B Rh (D) positive phenotype

Indian Journal of Pathology & Microbiology, 2023

Research paper thumbnail of Upholding routine hours blood collections against the night-shift timings

Transfusion Clinique Et Biologique, Dec 1, 2022

Research paper thumbnail of Averting transfusion related catastrophe during blood administration: Backing transfusion bioethics

Transfusion Clinique Et Biologique, Feb 1, 2023

Research paper thumbnail of Assessing the ethical and psychological impact of breaking the bad news to serology reactive blood donors

Éthique & Santé, Jun 1, 2021

Summary Telling the truth is the foremost responsibility of any physician towards his or her clie... more Summary Telling the truth is the foremost responsibility of any physician towards his or her clients. This applies more so to the blood centre physician (BCP) and should not be overlooked when he or she has to break the bad news to the serology reactive blood donors (SRBD) about their transfusion transmissible infection (TTI) results. Additionally, the donor notification and post-test discussion (PTD) must be done in a trust laden atmosphere based on all the four ethical principles, namely, the autonomy of individuals, beneficence, non-maleficence and justice in an appropriately structured manner. Therefore, having an overall TTI seroprevalence of 1.68% amongst the blood donors attending our blood centre, we sought out to assess the various ethical and psychological issues faced by both the SRBD and the BCP during their PTD in our facility.

Research paper thumbnail of Reverse algorithm for screening of syphilis and trends in prevalence among blood donors in Coastal Karnataka

Transfusion Clinique Et Biologique, Aug 1, 2022

Research paper thumbnail of Indian blood donor selection guidelines: Review in the context of the ongoing COVID-19 pandemic

Transfusion Clinique Et Biologique, May 1, 2021

The National Blood Transfusion Services under the aegis of the ministry of health and family welf... more The National Blood Transfusion Services under the aegis of the ministry of health and family welfare, India has recently issued guidelines regarding the blood donor selection criteria and the processing of blood. Care has been taken to make the blood transfusions safer. However, COVID-19 has disrupted the organization of the voluntary blood donation drives, whole blood donations [WBD] and restricted the donors' movement to the blood transfusion centres all across the world. While sickness and the need for transfusions are very much in place, the gap of demand against blood collection has widened. Additionally, with the monsoon season at hand, and the categorical challenges of a dengue outbreak, the subsequent need for blood components especially the platelet concentrates is going to rise. Some of the criteria laid for deferring a blood donor from his or her WBD need a categorical revision, considering these unprecedented times. We, therefore, critically analyzed the blood donor selection criteria and hereby, suggest an updating regarding the pre-donation haemoglobin, sexually transmitted diseases, lactation, pregnancy and many such subheadings. We also suggest collecting smaller blood volumes in the blood bags for the optimal benefit of the recipients both for now and also as a measure of pandemic preparedness for future use.

Research paper thumbnail of Extended blood group phenotyping of donors from the lower and middle Himalayan region of Uttarakhand India: A pilot study

Transfusion Clinique Et Biologique, May 1, 2023

Research paper thumbnail of Assessing the impetus and impediments to donate coronavirus disease-2019 convalescent plasma: A survey study from a tertiary care Indian blood center

Iraqi journal of hematology, 2022

Research paper thumbnail of The evolution of xenotransfusions through the ages

Transfusion Clinique Et Biologique, Feb 1, 2021

Research paper thumbnail of A rare report of H-partially deficient, non-secretor phenotype from India. An Ah like the rèunion and unlike a Para Bombay-Clarifying misinterpretations

Transfusion and Apheresis Science, Jul 1, 2023

Research paper thumbnail of Seroprevalence of SARS-CoV-2 among blood donors: A practical serosurveillance tool for COVID-19

Transfusion Clinique Et Biologique, Dec 1, 2021

Research paper thumbnail of A Cross-Sectional Comparative Characterization of Hematological Changes in Patients with COVID-19 Infection, Non-COVID Influenza-like Illnesses and Healthy Controls

Viruses

Introduction: Studies have documented the role of the “neutrophil-to-lymphocyte ratio” (NLR) in i... more Introduction: Studies have documented the role of the “neutrophil-to-lymphocyte ratio” (NLR) in influenza virus infection. In addition, morphometric parameters derived from automated analyzers on the volume, scatter and conductivity of monocytes, neutrophils and lymphocytes in many viral etiologies have helped with their early differentiation. With this background, we aimed to characterize the hematological changes of coronavirus-positive cases and also compare them with the healthy controls and patients affected by non-COVID Influenza-like illnesses so that early isolation could be considered. Material and Methods: This was a cross-sectional analytical study carried out in the years 2020–2022. All cases with COVID-19 and non-COVID-19 Influenza-like illnesses and healthy controls above 18 years were included. Cases were diagnosed according to the WHO guidelines. All samples were processed on a Unicel DxH 800 (Beckman Coulter, California, USA) automated hematology analyzer. The demog...

Research paper thumbnail of Conventional Gold Standard Techniques: Indeed a Saviour in the Era of Automation!!

Indian Journal of Hematology and Blood Transfusion, Mar 28, 2023

Research paper thumbnail of Assessing the impetus and impediments to donate coronavirus disease-2019 convalescent plasma: A survey study from a tertiary care Indian blood center

Iraqi Journal of Hematology

Research paper thumbnail of The Indian “blood storage centre” model for the provision of safe blood towards obstetric care in the remote regions of Uttarakhand

Transfusion Clinique et Biologique

Research paper thumbnail of Endorsing a permanent lifting of the ban on men who have sex with men and transgender from donating their whole blood

Indian Journal of Sexually Transmitted Diseases and AIDS

Research paper thumbnail of COVID-19 vaccination: The impact on the selection criteria of the convalescent plasma donors

Transfusion Clinique et Biologique, 2021

Clinical management protocols for COVID-19 are evolving rapidly as more information about the epi... more Clinical management protocols for COVID-19 are evolving rapidly as more information about the epidemiology and pathophysiological changes in COVID-19 becomes available. However, no definite treatment of COVID-19 pandemic has been found till date. The COVID-19 convalescent plasma (CCP) therapy has emerged as an important investigational therapy in the management of COVID-19 patients. Additionally, the regulatory agencies, in particular, the Indian blood transfusion council must release some interim recommendations for the blood centres on the CCP blood donor eligibility criteria after COVID-19 vaccination. More clinical trials are needed to know the efficacy of the CCP harvested from COVID-19 recovered individuals who have been vaccinated against the COVID-19 recovered individuals who are not vaccinated to understand the vaccine impact on the IgG titre of anti-SARS-Cov-2 antibodies.

Research paper thumbnail of Establishing a regional rare blood donor registry in Uttarakhand, India

Global journal of transfusion medicine, Dec 31, 2022

Research paper thumbnail of The Quandary of a Healthy (Child) Sibling Stem Cell Donor

Indian Journal of Medical and Paediatric Oncology, Jul 1, 2020

Research paper thumbnail of Imperishable blood stains splattered for Humanity: Reappraising the Shroud of Turin

Transfusion Clinique et Biologique

Research paper thumbnail of Reporting an immune-mediated neonatal hyperbilirubinemia following Rh (D) isoimmunization in an Indian term newborn bearing A<sub>MFA</sub> B Rh (D) positive phenotype

Indian Journal of Pathology & Microbiology, 2023

Research paper thumbnail of Upholding routine hours blood collections against the night-shift timings

Transfusion Clinique Et Biologique, Dec 1, 2022

Research paper thumbnail of Averting transfusion related catastrophe during blood administration: Backing transfusion bioethics

Transfusion Clinique Et Biologique, Feb 1, 2023

Research paper thumbnail of Assessing the ethical and psychological impact of breaking the bad news to serology reactive blood donors

Éthique & Santé, Jun 1, 2021

Summary Telling the truth is the foremost responsibility of any physician towards his or her clie... more Summary Telling the truth is the foremost responsibility of any physician towards his or her clients. This applies more so to the blood centre physician (BCP) and should not be overlooked when he or she has to break the bad news to the serology reactive blood donors (SRBD) about their transfusion transmissible infection (TTI) results. Additionally, the donor notification and post-test discussion (PTD) must be done in a trust laden atmosphere based on all the four ethical principles, namely, the autonomy of individuals, beneficence, non-maleficence and justice in an appropriately structured manner. Therefore, having an overall TTI seroprevalence of 1.68% amongst the blood donors attending our blood centre, we sought out to assess the various ethical and psychological issues faced by both the SRBD and the BCP during their PTD in our facility.

Research paper thumbnail of Reverse algorithm for screening of syphilis and trends in prevalence among blood donors in Coastal Karnataka

Transfusion Clinique Et Biologique, Aug 1, 2022

Research paper thumbnail of Indian blood donor selection guidelines: Review in the context of the ongoing COVID-19 pandemic

Transfusion Clinique Et Biologique, May 1, 2021

The National Blood Transfusion Services under the aegis of the ministry of health and family welf... more The National Blood Transfusion Services under the aegis of the ministry of health and family welfare, India has recently issued guidelines regarding the blood donor selection criteria and the processing of blood. Care has been taken to make the blood transfusions safer. However, COVID-19 has disrupted the organization of the voluntary blood donation drives, whole blood donations [WBD] and restricted the donors' movement to the blood transfusion centres all across the world. While sickness and the need for transfusions are very much in place, the gap of demand against blood collection has widened. Additionally, with the monsoon season at hand, and the categorical challenges of a dengue outbreak, the subsequent need for blood components especially the platelet concentrates is going to rise. Some of the criteria laid for deferring a blood donor from his or her WBD need a categorical revision, considering these unprecedented times. We, therefore, critically analyzed the blood donor selection criteria and hereby, suggest an updating regarding the pre-donation haemoglobin, sexually transmitted diseases, lactation, pregnancy and many such subheadings. We also suggest collecting smaller blood volumes in the blood bags for the optimal benefit of the recipients both for now and also as a measure of pandemic preparedness for future use.

Research paper thumbnail of Extended blood group phenotyping of donors from the lower and middle Himalayan region of Uttarakhand India: A pilot study

Transfusion Clinique Et Biologique, May 1, 2023

Research paper thumbnail of Assessing the impetus and impediments to donate coronavirus disease-2019 convalescent plasma: A survey study from a tertiary care Indian blood center

Iraqi journal of hematology, 2022

Research paper thumbnail of The evolution of xenotransfusions through the ages

Transfusion Clinique Et Biologique, Feb 1, 2021

Research paper thumbnail of A rare report of H-partially deficient, non-secretor phenotype from India. An Ah like the rèunion and unlike a Para Bombay-Clarifying misinterpretations

Transfusion and Apheresis Science, Jul 1, 2023

Research paper thumbnail of Seroprevalence of SARS-CoV-2 among blood donors: A practical serosurveillance tool for COVID-19

Transfusion Clinique Et Biologique, Dec 1, 2021

Research paper thumbnail of A Cross-Sectional Comparative Characterization of Hematological Changes in Patients with COVID-19 Infection, Non-COVID Influenza-like Illnesses and Healthy Controls

Viruses

Introduction: Studies have documented the role of the “neutrophil-to-lymphocyte ratio” (NLR) in i... more Introduction: Studies have documented the role of the “neutrophil-to-lymphocyte ratio” (NLR) in influenza virus infection. In addition, morphometric parameters derived from automated analyzers on the volume, scatter and conductivity of monocytes, neutrophils and lymphocytes in many viral etiologies have helped with their early differentiation. With this background, we aimed to characterize the hematological changes of coronavirus-positive cases and also compare them with the healthy controls and patients affected by non-COVID Influenza-like illnesses so that early isolation could be considered. Material and Methods: This was a cross-sectional analytical study carried out in the years 2020–2022. All cases with COVID-19 and non-COVID-19 Influenza-like illnesses and healthy controls above 18 years were included. Cases were diagnosed according to the WHO guidelines. All samples were processed on a Unicel DxH 800 (Beckman Coulter, California, USA) automated hematology analyzer. The demog...

Research paper thumbnail of Conventional Gold Standard Techniques: Indeed a Saviour in the Era of Automation!!

Indian Journal of Hematology and Blood Transfusion, Mar 28, 2023

Research paper thumbnail of Assessing the impetus and impediments to donate coronavirus disease-2019 convalescent plasma: A survey study from a tertiary care Indian blood center

Iraqi Journal of Hematology

Research paper thumbnail of The Indian “blood storage centre” model for the provision of safe blood towards obstetric care in the remote regions of Uttarakhand

Transfusion Clinique et Biologique

Research paper thumbnail of Endorsing a permanent lifting of the ban on men who have sex with men and transgender from donating their whole blood

Indian Journal of Sexually Transmitted Diseases and AIDS

Research paper thumbnail of COVID-19 vaccination: The impact on the selection criteria of the convalescent plasma donors

Transfusion Clinique et Biologique, 2021

Clinical management protocols for COVID-19 are evolving rapidly as more information about the epi... more Clinical management protocols for COVID-19 are evolving rapidly as more information about the epidemiology and pathophysiological changes in COVID-19 becomes available. However, no definite treatment of COVID-19 pandemic has been found till date. The COVID-19 convalescent plasma (CCP) therapy has emerged as an important investigational therapy in the management of COVID-19 patients. Additionally, the regulatory agencies, in particular, the Indian blood transfusion council must release some interim recommendations for the blood centres on the CCP blood donor eligibility criteria after COVID-19 vaccination. More clinical trials are needed to know the efficacy of the CCP harvested from COVID-19 recovered individuals who have been vaccinated against the COVID-19 recovered individuals who are not vaccinated to understand the vaccine impact on the IgG titre of anti-SARS-Cov-2 antibodies.