ICD-10-CM Diagnosis Code A00.9 - Cholera, unspecified (original) (raw)
ICD List 2025-2026 Edition
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- 2026 ICD-10-CM Code A00.9
Cholera, unspecified
ICD-10-CM Code:
A00.9
ICD-10 Code for:
Cholera, unspecified
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:
A00.9 is a billable diagnosis code used to specify a medical diagnosis of cholera, unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.
Unspecified diagnosis codes like A00.9 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.
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The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Cholera
- Cholera - non-O1 group vibrio
- Cholera - O139 group Vibrio cholerae
- Intestinal infection caused by Vibrio cholerae non-O139
- Intestinal infection caused by Vibrio cholerae O1
- Non-O1 and non-O139 Vibrio cholerae infection
- Vibrio cholerae enteritis of intestine
- Vibrio cholerae enteritis of small intestine
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
CCSR Code: INF003
Inpatient Default: N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.
CCSR Code: DIG001
Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Cholera
an acute diarrheal disease endemic in india and southeast asia whose causative agent is vibrio cholerae. this condition can lead to severe dehydration in a matter of hours unless quickly treated.
Cholera Morbus
an old term that is no longer used in the scientific literature. cholera morbus refers to acute gastroenteritis occurring in summer or autumn; characterized by severe cramps, diarrhea, and vomiting.
Cholera Toxin
an enterotoxin from vibrio cholerae. it consists of two major protomers, the heavy (h) or a subunit and the b protomer which consists of 5 light (l) or b subunits. the catalytic a subunit is proteolytically cleaved into fragments a1 and a2. the a1 fragment is a mono(adp-ribose) transferase. the b protomer binds cholera toxin to intestinal epithelial cells and facilitates the uptake of the a1 fragment. the a1 catalyzed transfer of adp-ribose to the alpha subunits of heterotrimeric g proteins activates the production of cyclic amp. increased levels of cyclic amp are thought to modulate release of fluid and electrolytes from intestinal crypt cells.
Cholera Vaccines
vaccines or candidate vaccines used to prevent infection with vibrio cholerae. the original cholera vaccine consisted of killed bacteria, but other kinds of vaccines now exist.
Classical Swine Fever
an acute, highly contagious disease affecting swine of all ages and caused by the classical swine fever virus. it has a sudden onset with high morbidity and mortality.
Classical Swine Fever Virus
a species of the pestivirus genus causing exceedingly contagious and fatal hemorrhagic disease of swine.
Gastrointestinal Diseases
diseases in any segment of the gastrointestinal tract from esophagus to rectum.
Vipoma
a tumor that secretes vasoactive intestinal peptide, a neuropeptide that causes vasodilation; relaxation of smooth muscles; watery diarrhea; hypokalemia; and hypochlorhydria. vipomas, derived from the pancreatic islet cells, generally are malignant and can secrete other hormones. in most cases, vipomas are located in the pancreas but can be found in extrapancreatic sites.
Vibrio cholerae
the etiologic agent of cholera.
Gastroenteritis
inflammation of any segment of the gastrointestinal tract from esophagus to rectum. causes of gastroenteritis are many including genetic, infection, hypersensitivity, drug effects, and cancer.
Pestivirus
a genus of flaviviridae, also known as mucosal disease virus group, which is not arthropod-borne. transmission is by direct and indirect contact, and by transplacental and congenital transmission. species include border disease virus, bovine viral diarrhea virus (diarrhea virus, bovine viral), and classical swine fever virus.
Cholera
an acute diarrheal illness caused by consuming water or food contaminated by the bacterium vibrio cholerae. adequate rehydration is key to surviving this illness.
Cholera Toxin
secreted by vibrio cholerae, cholera toxin is a natural bacterial enterotoxin consisting of major components heavy a- and light b peptides (choleragenoid) that initiates a signaling cascade in intestinal epithelial cells causing a dysfunction of chloride channels, loss of water, and diarrhea. b peptide anchors the protein to epithelia; a peptide enters the cytoplasm and activates adenylate cyclase. due to its cytotoxicity, cholera toxin is being studied for tumor cell targeting and cancer chemotherapy. (nci04)
Cholera Toxin B Subunit IgG Antibody Measurement|CTBIGGAB|Cholera Toxin B Subunit IgG Antibody|Cholera Toxin B Subunit IgG Antibody
the determination of the amount of cholera toxin b subunit igg antibody present in a sample.
Cholera Toxin B Subunit|CTB|VIBRIO CHOLERA TOXIN B SUBUNIT
the approximately 55 kda, receptor binding b subunit of the cholera toxin and the virulence factor for vibrio cholerae.
Salmonella enterica Serotype choleraesuis var. decatur|SALMONELLA CHOLERAESUIS VAR. DECATUR|Salmonella decatur
a gram-negative, rod-shaped serotype of the bacteria genus salmonella, species salmonella enterica, subspecies enterica. salmonella decatur, a rare human pathogen, was formerly classified as serotype choleraesuis variant decatur.
Salmonella Serotype Choleraesuis|SALMONELLA SEROTYPE CHOLERAESUIS|Salmonella enterica subsp. enterica serovar Choleraesuis
any bacterial organism that can be assigned to the genus salmonella with serotype choleraesuis.
Vibrio cholerae DNA Measurement|VCHDNA|Vibrio cholerae DNA|Vibrio cholerae DNA
the determination of the amount of vibrio cholerae dna present in a sample.
Vibrio cholerae, Vibrio parahaemolyticus, and/or Vibrio vulnificus DNA Measurement|C166008|V. chol/parahaemolyticus/vulnificus DNA|V. chol/parahaemolyticus/vulnificus DNA|Vibrio cholerae/parahaemolyticus/vulnificus DNA
the determination of the amount of vibrio cholerae, vibrio parahaemolyticus, and/or vibrio vulnificus dna present in a sample.
Vibrio cholerae|VIBRIO CHOLERAE|Vibrio comma|Vibrio comma
a species of facultatively anaerobic, gram negative, curved rod shaped bacteria assigned to the phylum proteobacteria. this species is motile, oxidase and lipase positive, can use a wide variety of sugars as carbon sources, does not require salt for growth, and produces cholera toxin. v. cholerae is the causative agent of cholera.
Vibrio mimicus|Sucrose Negative Vibrio cholerae|VIBRIO MIMICUS
a species of facultatively anaerobic, gram negative, curved rod shaped bacteria assigned to the phylum proteobacteria. this species is motile, oxidase positive, lipase negative, hemolytic, cannot use sucrose as a carbon source and does not require salt for growth. v. mimicus is a found in marine and fresh water environments and is a pathogen that causes gastroenteritis.
WDHA Syndrome|Islet Cell WDHA Syndrome|Pancreatic Cholera|Pancreatic WDHA Syndrome|Verner Morrison Syndrome|WDHH|Watery Diarrhea Syndrome|Watery Diarrhea with Hypokalemic Alkalosis|Watery Diarrhea, Hypokalemia, and Achlorhydria Syndrome
a rare syndrome characterized by severe watery diarrhea, hypokalemia, and achlorhydria. it is caused by the oversecretion of vasoactive intestinal peptide from the pancreatic islet cells.
Cholera Toxin B Subunit IgG Antibody Measurement
the determination of the amount of cholera toxin b subunit igg antibody present in a sample.
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Cholera (Asiatic) (epidemic) (malignant) - A00.9
- - due to Vibrio cholerae 01 - A00.9
References found for this diagnosis code in the External Cause of Injuries Index:
- Cholera(Asiatic) (epidemic) (malignant)
- Cholera(Asiatic) (epidemic) (malignant)
- due to Vibrio cholerae 01
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
ICD-9-CM: 001.9
This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.
Cholera
Cholera is a bacterial infection that causes diarrhea. The cholera bacterium is usually found in water or food that has been contaminated by feces (poop). Cholera is rare in the US. You may get it if you travel to parts of the world with poor water and sewage treatment. Outbreaks can also happen after disasters. The disease is not likely to spread directly from person to person.
Cholera infections are often mild. Some people don't have any symptoms. If you do get symptoms, they usually start 2 to 3 days after infection. The most common symptom is watery diarrhea.
In some cases, the infection can be severe, causing lots of watery diarrhea, vomiting, and leg cramps. Because you quickly lose body fluids, you are at risk for dehydration and shock. Without treatment, you could die within hours. If you think that you might have cholera, you should get medical care right away.
Doctors diagnose cholera with a stool sample or rectal swab. Treatment is the replacement of the fluid and salts that you lost through the diarrhea. This is usually with a rehydration solution that you drink. People with severe cases may need an I.V. to replace the fluids. Some of them may also need antibiotics. Most people who get fluid replacement right away will recover.
There are vaccines to prevent cholera. One of them is available for adults in the U.S. Very few Americans need it, because most people do not visit areas that have an active cholera outbreak.
There are also simple steps you can take to help to prevent cholera infection:
- Use only bottled or purified water for drinking, washing dishes, making ice cubes, and brushing your teeth
- If you do use tap water, boil it or use iodine tablets
- Wash your hands often with soap and clean water
- Make sure that the cooked food you eat is fully cooked and served hot
- Avoid unwashed or unpeeled raw fruits and vegetables
Centers for Disease Control and Prevention
FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026
FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025
FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
