ICD-10-CM Diagnosis Code C78.4 - Secondary malignant neoplasm of small intestine (original) (raw)

ICD List 2025-2026 Edition

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2. ICD-10-CM Codes
3. C00–D49
4. C76-C80
5. C78
6. 2026 ICD-10-CM Code C78.4

Secondary malignant neoplasm of small intestine

ICD-10-CM Code:

C78.4

ICD-10 Code for:

Secondary malignant neoplasm of small intestine

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Chronic

Code Navigator:

C78.4 is a billable diagnosis code used to specify a medical diagnosis of secondary malignant neoplasm of small intestine. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic duodenojejunal junction ; Neoplasm, neoplastic duodenum ; Neoplasm, neoplastic ileum ; Neoplasm, neoplastic intestine, intestinal small ; Neoplasm, neoplastic intestine, intestinal small duodenum ; Neoplasm, neoplastic intestine, intestinal small ileum ; Neoplasm, neoplastic intestine, intestinal small jejunum ; etc

1. Code Information
2. Approximate Synonyms
3. Clinical Classification
4. Clinical Information
5. Tabular List of Diseases and Injuries
6. Diagnostic Related Groups Mapping
7. Convert to ICD-9 Code
8. Table of Neoplasms
9. Patient Education
10. Other Codes Used Similar Conditions
11. Code History

• Neoplasms
  C00–D49
  • Malignant neoplasms of ill-defined, other secondary and unspecified sites
    C76-C80
    * Secondary malignant neoplasm of respiratory and digestive organs
    C78

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

• Adenocarcinoma of Meckel diverticulum
• Adenocarcinoma of small intestine
• Malignant neoplasm of ileum
• Malignant neoplasm of jejunum
• Malignant neoplasm of Meckel's diverticulum
• Malignant neoplasm of Meckel's diverticulum
• Metastatic adenocarcinoma to Meckel diverticulum
• Metastatic carcinoma to duodenum
• Metastatic malignant neoplasm to duodenum
• Metastatic malignant neoplasm to duodenum
• Metastatic malignant neoplasm to ileum
• Metastatic malignant neoplasm to jejunum
• Metastatic malignant neoplasm to Meckel's diverticulum
• Metastatic malignant neoplasm to Meckel's diverticulum
• Metastatic malignant neoplasm to small intestine
• Metastatic malignant neoplasm to small intestine
• Metastatic malignant neoplasm to small intestine
• Metastatic malignant neoplasm to small intestine
• Metastatic squamous cell carcinoma to small intestine
• Neoplasm of Meckel's diverticulum
• Neoplasm of Meckel's diverticulum
• Squamous cell carcinoma of small intestine
• Tumor invades beyond pancreatic capsule to adjacent structures AND/OR organs
• Tumor invades beyond pancreatic capsule to duodenum

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: NEO070

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

• Duodenal Neoplasms

tumors or cancer of the duodenum.

• Duodenum

the shortest and widest portion of the small intestine adjacent to the pylorus of the stomach. it is named for having the length equal to about the width of 12 fingers.

• Jejunal Neoplasms

tumors or cancer in the jejunum region of the small intestine (intestine, small).

• Jejunum

the middle portion of the small intestine, between duodenum and ileum. it represents about 2/5 of the remaining portion of the small intestine below duodenum.

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 197.4

This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Filter table of neoplasms:

Intestinal Cancer

Your small intestine is part of your digestive system. It is a long tube that connects your stomach to your large intestine. Intestinal cancer is rare, but eating a high-fat diet or having Crohn's disease, celiac disease, or a history of colonic polyps can increase your risk.

Possible signs of small intestine cancer include:

• Abdominal pain
• Weight loss for no reason
• Blood in the stool
• A lump in the abdomen

Imaging tests that create pictures of the small intestine and the area around it can help diagnose intestinal cancer and show whether it has spread.

Surgery is the most common treatment. Additional options include chemotherapy, radiation therapy, or a combination.

NIH: National Cancer Institute

[Learn More in MedlinePlus]

• FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026

• FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024

• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023

• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022

• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019

• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018

• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017

• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

• Previous Code: C78.39

• Parent Code: C78

• Next Code: C78.5