ICD-10-CM Diagnosis Code D21.4 - Benign neoplasm of connective and other soft tissue of abdomen (original) (raw)

ICD List 2025-2026 Edition

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2. ICD-10-CM Codes
3. C00–D49
4. D10-D36
5. D21
6. 2026 ICD-10-CM Code D21.4

Benign neoplasm of connective and other soft tissue of abdomen

ICD-10-CM Code:

D21.4

ICD-10 Code for:

Benign neoplasm of connective and oth soft tissue of abdomen

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Not chronic

Code Navigator:

D21.4 is a billable diagnosis code used to specify a medical diagnosis of benign neoplasm of connective and other soft tissue of abdomen. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic abdomen, abdominal wall [See Also: Neoplasm, abdomen, wall, skin] connective tissue ; Neoplasm, neoplastic aorta (thoracic) abdominal ; Neoplasm, neoplastic connective tissue NEC abdomen ; Neoplasm, neoplastic connective tissue NEC abdominal wall ; Neoplasm, neoplastic connective tissue NEC gastric ; Neoplasm, neoplastic connective tissue NEC gastrointestinal ; Neoplasm, neoplastic connective tissue NEC hypochondrium ; etc

1. Code Information
2. Approximate Synonyms
3. Clinical Classification
4. Tabular List of Diseases and Injuries
5. Index to Diseases and Injuries References
7. Diagnostic Related Groups Mapping
8. Convert to ICD-9 Code
9. Table of Neoplasms
10. Patient Education
11. Other Codes Used Similar Conditions
12. Code History

• Neoplasms
  C00–D49
  • Benign neoplasms, except benign neuroendocrine tumors
    D10-D36
    * Other benign neoplasms of connective and other soft tissue
    D21

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

• Benign neoplasm of blood vessel of abdomen
• Benign neoplasm of colostomy site
• Benign neoplasm of muscle of abdomen
• Benign neoplasm of muscle of trunk
• Benign neoplasm of soft tissues of abdomen
• Neoplasm of blood vessel of abdomen
• Neoplasm of muscle of abdomen

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: NEO073

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

• - Tumor - See Also: Neoplasm, unspecified behavior, by site;
  • - stromal
    * - gastric - D48.19
    * - benign - D21.4
    * - gastrointestinal - C49.A
    * - benign - D21.4
    * - intestine
    * - benign - D21.4
    * - stomach - C49.A2
    * - benign - D21.4

References found for this diagnosis code in the External Cause of Injuries Index:

• Tumor
  • stromal
    • gastric
      • benign
• Tumor
  • stromal
    • gastrointestinal
      • benign
• Tumor
  • stromal
    • intestine
      • benign
• Tumor
  • stromal
    • stomach
      • benign

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 215.5

This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Filter table of neoplasms:

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Tumors are made up of extra cells. Normally, cells grow and divide to form new cells as your body needs them. When cells grow old, they die, and new cells take their place. Sometimes, this process goes wrong. New cells form when your body does not need them, and old cells do not die when they should. These extra cells can divide without stopping and may form a tumor.

Treatment often involves surgery. Benign tumors usually don't grow back.

NIH: National Cancer Institute

[Learn More in MedlinePlus]

• FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026

• FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024

• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023

• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022

• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019

• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018

• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017

• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

• Previous Code: D21.3

• Parent Code: D21

• Next Code: D21.5