ICD-10-CM Diagnosis Code E52 - Niacin deficiency [pellagra] (original) (raw)
ICD List 2025-2026 Edition
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- 2026 ICD-10-CM Code E52
Niacin deficiency [pellagra]
ICD-10-CM Code:
E52
ICD-10 Code for:
Niacin deficiency [pellagra]
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:
E52 is a billable diagnosis code used to specify a medical diagnosis of niacin deficiency [pellagra]. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.
- Code Information
- Approximate Synonyms
- Clinical Classification
- Clinical Information
- Tabular List of Diseases and Injuries
- Index to Diseases and Injuries References
- Diagnostic Related Groups Mapping
- Convert to ICD-9 Code
- Patient Education
- Code History
- Endocrine, nutritional and metabolic diseases
E00–E89
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Alcoholic pellagra
- Deficiency of isocitrate dehydrogenase
- Dementia due to niacin deficiency
- Dementia due to nutritional deficiency
- Dementia due to nutritional deficiency
- Dementia due to pellagra
- Inadequate intake of niacin
- Niacin deficiency
- Niacin deficiency
- Niacin deficiency
- Niacin deficiency
- Pellagra
- Pellagra
- Pellagra
- Pellagra caused by drug
- Pellagra neuropathy
- Pellagra neuropathy
- Polyneuropathy in pellagra
- Thiamine and niacin deficiency
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
CCSR Code: END007
Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Pellagra
a disease due to deficiency of niacin, a b-complex vitamin, or its precursor tryptophan. it is characterized by scaly dermatitis which is often associated with diarrhea and dementia (the three d's).
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Acid
- - deficiency
* - amide nicotinic - E52
* - nicotinic - E52
- - deficiency
- - Alcohol, alcoholic, alcohol-induced
- - pellagra - E52
- - Avitaminosis (multiple) - See Also: Deficiency, vitamin; - E56.9
- - B - E53.9
* - with
* - pellagra - E52 - - nicotinic acid - E52
- - B - E53.9
- - Cheilosis (angular) - K13.0
- - with pellagra - E52
- - Deficiency, deficient
- - niacin (amide) (-tryptophan) - E52
- - nicotinamide - E52
- - nicotinic acid - E52
- - vitamin (multiple) NOS - E56.9
* - B (complex) NOS - E53.9
* - with
* - pellagra - E52
* - nicotinic - E52
* - PP (pellagra-preventing) - E52
- - Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety) - F03.90
- - in (due to)
* - niacin deficiency - See Also: Dementia, in, diseases specified elsewhere; - E52
* - with behavioral disturbance - See Also: Dementia, in, diseases specified elsewhere; - E52
* - pellagra - See Also: Dementia, in, diseases specified elsewhere; - E52
* - with behavioral disturbance - See Also: Dementia, in, diseases specified elsewhere; - E52
- - in (due to)
- - Dermatitis (eczematous) - L30.9
- - pellagrous - E52
- - Encephalopathy (acute) - G93.40
- - pellagrous - E52
- - Erythema, erythematous (infectional) (inflammation) - L53.9
- - endemic - E52
- - Gingivitis - K05.10
- - pellagrous - E52
- - Glossitis (chronic superficial) (gangrenous) (Moeller's) - K14.0
- - pellagrous - E52
- - Niacin (amide) deficiency - E52
- - Nicotinic acid deficiency - E52
- - Pellagra (alcoholic) - E52
- - with
* - polyneuropathy - E52
- - with
- - Polioencephalopathy, superior hemorrhagic - E51.2
- - Polyneuropathy (peripheral) - G62.9
- - in (due to)
* - pellagra - E52
- - in (due to)
- - Syndrome - See Also: Disease;
- - pellagroid - E52
References found for this diagnosis code in the External Cause of Injuries Index:
- Acid
- deficiency
- amide nicotinic
- deficiency
- Acid
- deficiency
- nicotinic
- deficiency
- Alcohol, alcoholic, alcohol-induced
- pellagra
- Avitaminosis(multiple)
- B
- with
- pellagra
- with
- B
- Avitaminosis(multiple)
- nicotinic acid
- Cheilosis(angular)
- with pellagra
- Deficiency, deficient
- niacin (amide) (-tryptophan)
- Deficiency, deficient
- nicotinamide
- Deficiency, deficient
- nicotinic acid
- Deficiency, deficient
- vitamin (multiple) NOS
- B (complex) NOS
- with
- pellagra
- with
- B (complex) NOS
- vitamin (multiple) NOS
- Deficiency, deficient
- vitamin (multiple) NOS
- nicotinic
- vitamin (multiple) NOS
- Deficiency, deficient
- vitamin (multiple) NOS
- PP (pellagra-preventing)
- vitamin (multiple) NOS
- Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
- in (due to)
- niacin deficiency
- in (due to)
- Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
- in (due to)
- niacin deficiency
- with behavioral disturbance
- niacin deficiency
- in (due to)
- Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
- in (due to)
- pellagra
- in (due to)
- Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
- in (due to)
- pellagra
- with behavioral disturbance
- pellagra
- in (due to)
- Dermatitis(eczematous)
- pellagrous
- Encephalopathy(acute)
- pellagrous
- Erythema, erythematous(infectional) (inflammation)
- endemic
- Gingivitis
- pellagrous
- Glossitis(chronic superficial) (gangrenous) (Moeller's)
- pellagrous
- Niacin(amide) deficiency
- Nicotinic acid deficiency
- Pellagra(alcoholic)
- Pellagra(alcoholic)
- with
- polyneuropathy
- with
- Polioencephalopathy, superior hemorrhagic
- with
- pellagra
- with
- Polyneuropathy(peripheral)
- in (due to)
- pellagra
- in (due to)
- Syndrome
- pellagroid
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
ICD-9-CM: 265.2
This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.
B Vitamins
The B vitamins are:
- B1 (thiamine)
- B2 (riboflavin)
- B3 (niacin)
- B5 (pantothenic acid)
- B6
- B7 (biotin)
- B12
- Folic acid
These vitamins help the process your body uses to get or make energy from the food you eat. They also help form red blood cells. You can get B vitamins from proteins such as fish, poultry, meat, eggs, and dairy products. Leafy green vegetables, beans, and peas also have B vitamins. Many cereals and some breads have added B vitamins.
Not getting enough of certain B vitamins can cause diseases. A lack of B12 or B6 can cause anemia.
Malnutrition
What is malnutrition?
Malnutrition means that your body isn't getting enough calories or the right balance of nutrients to stay healthy. This can happen if you don't get enough protein, carbohydrates, and fats, eat too much unhealthy food, or don't get the vitamins and minerals your body needs.
Malnutrition can affect people of all ages, but children, older adults, and people with chronic (long-term) health problems have a higher risk.
What are the types of malnutrition?
Most people think of undernutrition with malnutrition. But malnutrition can refer to undernutrition, overnutrition, or an imbalance of nutrients.
Types of malnutrition include:
- Protein-energy undernutrition, also called macronutrient undernutrition, happens when your body doesn't get enough protein or calories from food. Two serious forms of this are kwashiorkor and marasmus.
- An imbalanced nutritional status occurs when you are not getting the right mix of nutrients. You may get enough calories, but not enough vitamins or minerals.
- Vitamin deficiency diseases happen when your body doesn't get enough of certain vitamins. Without the right vitamins, your body cannot stay healthy and may develop specific diseases. For example, scurvy can develop from too little vitamin C, rickets from too little vitamin D, and anemia from too little iron or vitamin B12.
- Failure to thrive occurs when children don't gain weight or grow as expected. This may be due to not getting enough food, trouble absorbing nutrients, or other health problems.
- Overnutrition can occur when your body gets too many calories or nutrients. This may lead to obesity or other health issues.
What causes malnutrition?
Malnutrition may occur for many reasons, including:
- An unbalanced diet that lacks variety or specific nutrients.
- Some medical issues, which could include malabsorption syndromes, dementia, eating disorders, depression, alcohol use disorder (AUD), or cancer.
- Problems with swallowing, digestion, or dental issues.
- Certain medicines that affect how food tastes and smells.
- Not being able to get food or cook due to things such as chronic illness, mobility issues, or low income.
Who is at risk for developing malnutrition?
Malnutrition can affect anyone, but some people have a higher risk than others. This includes people who:
- Don't have enough knowledge about nutrition
- Don't have access to a variety of food
- Are older adults or children
- Have a low income
- Have a chronic (long-term) illness
What are the symptoms of malnutrition?
The symptoms of malnutrition can vary. You may have no symptoms, but if you do, they may include:
- Fatigue and weakness
- Dizziness
- Losing weight without trying
- Low body weight
- Slow growth or development in children
- Frequent infections or slow healing
- Dry skin or brittle hair and nails
- Swelling in the legs, feet, or belly
How is malnutrition diagnosed?
To check for malnutrition, your provider may:
- Do a nutritional screening, which may include questions about weight loss, changes in your appetite, and your ability to eat.
- Do a physical exam and order blood tests to check for signs that you don't have enough nutrients.
- Refer you to other providers that specialize in nutrition, such as a dietician.
What are the treatments for malnutrition?
Treatment for malnutrition may include improving your diet, replacing missing nutrients, and treating the underlying cause.
Can malnutrition be prevented?
To help prevent malnutrition, eat a healthy diet with many different foods. Talk with your provider if you are worried about your diet, weight loss, or your child's growth.
FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026
FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025
FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
