ICD-10-CM Diagnosis Code N04.8 - Nephrotic syndrome with other morphologic changes (original) (raw)

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ICD List 2025-2026 Edition

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Nephrotic syndrome with other morphologic changes

ICD-10-CM Code:

N04.8

ICD-10 Code for:

Nephrotic syndrome with other morphologic changes

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Chronic

Code Navigator:

N04.8 is a billable diagnosis code used to specify a medical diagnosis of nephrotic syndrome with other morphologic changes. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

  1. Code Information
  2. Approximate Synonyms
  3. Clinical Classification
  4. Clinical Information
  5. Replaced Code
  6. Tabular List of Diseases and Injuries
  7. Index to Diseases and Injuries References
  9. Diagnostic Related Groups Mapping
  10. Convert to ICD-9 Code
  11. Patient Education
  12. Other Codes Used Similar Conditions
  13. Code History

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: GEN001

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

a rare autosomal recessive inherited nephrotic syndrome that is present in the first week of life. it manifests with edema and proteinuria and usually has a poor prognosis.

nephrotic syndrome associated with a cytomegalovirus infection, most commonly presenting in the first three months of life.

nephrotic syndrome within the first three motnhs of life, characterized initially by increased mesangial matrix, with or without hypertrophy and hyperplasia of podocytes, and eventual glomerular sclerosis.

nephrotic syndrome within the first three months of life, characterized by scarring of the glomerulus, in which only part of the glomerulus is involved, and less than 50% of the glomeruli are affected.

nephrotic syndrome presenting within the first three months of life, and which is associated with an infectious process.

nephrotic syndrome associated with rubella, most commonly presenting in the first three months of life.

nephrotic syndrome associated with toxoplasmosis, most commonly presenting in the first three months of life.

nephrotic syndrome associated with syphilis, most commonly presenting in the first three months of life.

nephrotic syndrome attributed to mutation(s) in the nphs1 gene, which encodes the protein nephrin, and most commonly presents during the first three months of life.

This code was replaced in the 2026 ICD-10-CM code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This code was replaced for the FY 2026 (October 1, 2025 - September 30, 2026).

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

References found for this diagnosis code in the External Cause of Injuries Index:

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 581.89

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters. It goes to your bladder, which stores the urine until you go to the bathroom.

Most kidney diseases attack the nephrons. This damage may leave kidneys unable to remove wastes. Causes can include genetic problems, injuries, or medicines. You have a higher risk of kidney disease if you have diabetes, high blood pressure, or a close family member with kidney disease. Chronic kidney disease damages the nephrons slowly over several years. Other kidney problems include:

Your doctor can do blood and urine tests to check if you have kidney disease. If your kidneys fail, you will need dialysis or a kidney transplant.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

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