ICD-10-CM Diagnosis Code O23.21 - Infections of urethra in pregnancy, first trimester (original) (raw)

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ICD List 2025-2026 Edition

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Infections of urethra in pregnancy, first trimester

ICD-10-CM Code:

O23.21

ICD-10 Code for:

Infections of urethra in pregnancy, first trimester

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Not chronic

Code Navigator:

O23.21 is a billable diagnosis code used to specify a medical diagnosis of infections of urethra in pregnancy, first trimester. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

The code O23.21 is applicable to female patients aged 12 through 55 years inclusive. It is clinically and virtually impossible to use this code on a non-female patient outside the stated age range.

This medical diagnosis code is frequently used in OB/GYN medical specialties to designate conditions such maternal disorders related to pregnancy.

  1. Code Information
  2. Clinical Classification
  3. Tabular List of Diseases and Injuries
  4. Code Edits
  5. Diagnostic Related Groups Mapping
  6. Convert to ICD-9 Code
  7. Patient Education
  8. Other Codes Used Similar Conditions
  9. Code History

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: PRG028

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

CCSR Code: GEN004

Inpatient Default: N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.

The Medicare Code Editor (MCE) detects errors and inconsistencies in ICD-10-CM diagnosis coding that can affect Medicare claim validity. These Medicare code edits help medical coders and billing professionals determine when a diagnosis code is not appropriate as a principal diagnosis, does not meet coverage criteria. Use this list to verify whether a code is valid for Medicare billing and to avoid claim rejections or denials due to diagnosis coding issues.

The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 646.61

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

ICD-9-CM: 646.63

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

Infections and Pregnancy

How can infections affect your pregnancy?

During pregnancy, some common infections such as the common cold or a skin infection do not usually cause serious problems. Some infections, such as the flu, can be more severe when you're pregnant. But other infections can be harmful to you, your fetus, or both.

Certain infections during pregnancy may lead to or cause complications or health problems for your fetus, such as:

What infections can be harmful during pregnancy?

Some infections that can be harmful during pregnancy include:

What are the symptoms of an infection during pregnancy?

Sometimes, it's hard to know what's normal during pregnancy. Symptoms of an infection can vary based on the infection. Talk with your health care provider about what symptoms to look for and how to keep healthy. But, if something is worrying you, share your symptoms with your provider for early detection and treatment of infections.

What are the treatments for infections during pregnancy?

If you do get an infection during pregnancy, contact your provider about treatment that will best protect you and your fetus. Only some medicines are safe during pregnancy.

Can infections during pregnancy be prevented?

Taking care of yourself and getting early and regular prenatal care from your provider may help identify and treat infections early.

To lower your risk of certain infections or prevent others:

Department of Health and Human Services, Office on Women's Health

[Learn More in MedlinePlus]

Urinary Tract Infections

The urinary system is the body's drainage system for removing wastes and extra water. It includes two kidneys, two ureters, a bladder, and a urethra. Urinary tract infections (UTIs) are the second most common type of infection in the body.

You may have a UTI if you notice:

People of any age or sex can get UTIs. But about four times as many women get UTIs as men. You're also at higher risk if you have diabetes, need a tube to drain your bladder, or have a spinal cord injury.

If you think you have a UTI it is important to see your doctor. Your doctor can tell if you have a UTI with a urine test. Treatment is with antibiotics.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

[Learn More in MedlinePlus]