ICD-10-CM Diagnosis Code R52 - Pain, unspecified (original) (raw)

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Pain, unspecified

ICD-10-CM Code:

R52

ICD-10 Code for:

Pain, unspecified

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Not chronic

Code Navigator:

R52 is a billable diagnosis code used to specify a medical diagnosis of pain, unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

Unspecified diagnosis codes like R52 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

  1. Code Information
  2. Approximate Synonyms
  3. Clinical Classification
  4. Clinical Information
  5. Tabular List of Diseases and Injuries
  6. Index to Diseases and Injuries References
  7. Diagnostic Related Groups Mapping
  8. Convert to ICD-9 Code
  9. Patient Education
  10. Code History

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: SYM016

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

sensation of discomfort, distress, or agony in the abdominal region.

intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.

pain in the joint.

acute or chronic pain located in the posterior regions of the thorax; lumbosacral region; or the adjacent regions.

acute pain that comes on rapidly despite the use of pain medication.

pain that may be caused by or related to cellular, tissue, and systemic changes that occur during neoplasm growth, tissue invasion, and metastasis.

cognitive and emotional processes encompassing magnification of pain-related stimuli, feelings of helplessness, and a generally pessimistic orientation.

a complex regional pain syndrome characterized by burning pain and marked sensitivity to touch (hyperesthesia) in the distribution of an injured peripheral nerve. autonomic dysfunction in the form of sudomotor (i.e., sympathetic innervation to sweat glands), vasomotor, and trophic skin changes may also occur. (adams et al., principles of neurology, 6th ed, p1359)

pressure, burning, or numbness in the chest.

a technique for visualizing chromosome aberrations using fluorescently labeled dna probes which are hybridized to chromosomal dna. multiple fluorochromes may be attached to the probes. upon hybridization, this produces a multicolored, or painted, effect with a unique color at each site of hybridization. this technique may also be used to identify cross-species homology by labeling probes from one species for hybridization with chromosomes from another species.

aching sensation that persists for more than a few months. it may or may not be associated with trauma or disease, and may persist after the initial injury has healed. its localization, character, and timing are more vague than with acute pain.

conditions characterized by pain involving an extremity or other body region, hyperesthesia, and localized autonomic dysfunction following injury to soft tissue or nerve. the pain is usually associated with erythema; skin temperature changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. the degree of pain and other manifestations is out of proportion to that expected from the inciting event. two subtypes of this condition have been described: type i; (reflex sympathetic dystrophy) and type ii; (causalgia). (from pain 1995 oct;63(1):127-33)

a condition with recurring discomfort or pain in the urinary bladder and the surrounding pelvic region without an identifiable disease. severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.

peripheral, autonomic, and cranial nerve disorders that are associated with diabetes mellitus. these conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (vasa nervorum). relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see oculomotor nerve diseases); mononeuropathy; mononeuropathy multiplex; diabetic amyotrophy; a painful polyneuropathy; autonomic neuropathy; and thoracoabdominal neuropathy. (from adams et al., principles of neurology, 6th ed, p1325)

painful menstruation.

a dull or sharp painful sensation associated with the outer or inner structures of the eyeball, having different causes.

neuralgic syndromes which feature chronic or recurrent facial pain as the primary manifestation of disease. disorders of the trigeminal and facial nerves are frequently associated with these conditions.

pain in the facial region including orofacial pain and craniofacial pain. associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as facial pain syndromes.

pain emanating from below the ribs and above the ilium.

the symptom of pain in the cranial region. it may be an isolated benign occurrence or manifestation of a wide variety of headache disorders.

a group of inherited disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and clinically by loss of sensation and autonomic dysfunction. there are five subtypes. type i features autosomal dominant inheritance and distal sensory involvement. type ii is characterized by autosomal inheritance and distal and proximal sensory loss. type iii is dysautonomia, familial. type iv features insensitivity to pain, heat intolerance, and mental deficiency. type v is characterized by a selective loss of pain with intact light touch and vibratory sensation. (from joynt, clinical neurology, 1995, ch51, pp142-4)

anxiety disorder of persistent and irrational fear of movement following an injury. it is related to perceived disability due to injury and catastrophizing in fear of (anticipated) pain and possibility of reinjury.

pain associated with obstetric labor in childbirth. it is caused primarily by uterine contraction as well as pressure on the cervix; bladder; and the gastrointestinal tract. labor pain mostly occurs in the abdomen; the groin; and the back.

acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous sprains and strains; intervertebral disk displacement; and other conditions.

pain in the breast generally classified as cyclical (associated with menstrual periods), or noncyclical, i.e. originating from the breast or nearby muscles or joints, ranging from minor discomfort to severely incapacitating.

discomfort stemming from muscles, ligaments, tendons, and bones.

painful sensation in the muscles.

muscular pain in numerous body regions that can be reproduced by pressure on trigger points, localized hardenings in skeletal muscle tissue. pain is referred to a location distant from the trigger points. a prime example is the temporomandibular joint dysfunction syndrome.

discomfort or more intense forms of pain that are localized to the cervical region. this term generally refers to pain in the posterior or lateral regions of the neck.

intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

dull or sharp aching pain caused by stimulated nociceptors due to tissue injury, inflammation or diseases. it can be divided into somatic or tissue pain and visceral pain.

peripheral afferent neurons which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. their cell bodies reside in the dorsal root ganglia. their peripheral terminals (nerve endings) innervate target tissues and transduce noxious stimuli via axons to the central nervous system.

pain originating from the disrupted function of pain-related sensory pathways in both the periphery and central nervous system (cns), leading to heightened sensitivity.

the broom-rape plant family of the order lamiales.

an unpleasant sensation induced by noxious stimuli which are detected by nerve endings of nociceptive neurons.

facilities providing diagnostic, therapeutic, and palliative services for patients with severe chronic pain. these may be free-standing clinics or hospital-based and serve ambulatory or inpatient populations. the approach is usually multidisciplinary. these clinics are often referred to as acute pain services. (from br med bull 1991 jul;47(3):762-85)

a syndrome characterized by indifference to pain despite the ability to distinguish noxious from non-noxious stimuli. absent corneal reflexes and intellectual disability may be associated. familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (adams et al., principles of neurology, 6th ed, p1343)

a form of therapy that employs a coordinated and interdisciplinary approach for easing the suffering and improving the quality of life of those experiencing pain.

scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.

the process by which pain is recognized and interpreted by the brain.

amount of stimulation required before the sensation of pain is experienced.

persistent pain that is refractory to some or all forms of treatment.

pain during the period after surgery.

pain associated with examination, treatment or procedures.

a type of pain that is perceived in an area away from the site where the pain arises, such as facial pain caused by lesion of the vagus nerve, or throat problem generating referred pain in the ear.

an emulsion of solid color which when spread over a surface leaves a thin decorative and or protective coating.

works of art formed primarily by the direct application of pigments suspended in oil, water, egg yolk, molten wax, or other liquid, arranged in masses of color, onto a generally two-dimensional surface. (getty att)

subjective cutaneous sensations (e.g., cold, warmth, tingling, pressure, etc.) that are experienced spontaneously in the absence of stimulation.

a syndrome characterized by retropatellar or peripatellar pain resulting from physical and biochemical changes in the patellofemoral joint. the pain is most prominent when ascending or descending stairs, squatting, or sitting with flexed knees. there is a lack of consensus on the etiology and treatment. the syndrome is often confused with (or accompanied by) chondromalacia patellae, the latter describing a pathological condition of the cartilage and not a syndrome.

discomfort associated with the bones that make up the pelvic girdle. it occurs frequently during pregnancy.

pain in the pelvic region of genital and non-genital origin.

perception of painful and nonpainful phantom sensations that occur following the complete or partial loss of a limb. the majority of individuals with an amputated extremity will experience the impression that the limb is still present, and in many cases, painful. (from neurol clin 1998 nov;16(4):919-36; brain 1998 sep;121(pt 9):1603-30)

a syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. this condition is most often precipitated by trauma to soft tissue or nerve complexes. the skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (adams et al., principles of neurology, 6th ed, p1360; pain 1995 oct;63(1):127-33)

abnormal behavioral or physiologic events that are associated with rem sleep, including rem sleep behavior disorder.

unilateral or bilateral pain of the shoulder. it is often caused by physical activities such as work or sports participation, but may also be pathologic in origin.

disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by another medical condition, by the direct effects of a substance, or by another mental disorder. the medically unexplained symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. in contrast to factitious disorders and malingering, the physical symptoms are not under voluntary control. (apa, dsm-v)

disorders of sensory information received from superficial and deep regions of the body. the somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. peripheral nervous system diseases; spinal cord diseases; and brain diseases may be associated with impaired or abnormal somatic sensation.

spontaneously remitting inflammatory condition of the thyroid gland, characterized by fever; muscle weakness; sore throat; severe thyroid pain; and an enlarged damaged gland containing giant cells. the disease frequently follows a viral infection.

pain originating from internal organs (viscera) associated with autonomic phenomena (pallor; sweating; nausea; and vomiting). it often becomes a referred pain.

complex pain syndrome with unknown etiology, characterized by constant or intermittent generalized vulva pain (generalized vulvodynia) or localized burning sensations in the vestibule area when pressure is applied (vestibulodynia, or vulvar vestibulitis syndrome). typically, vulvar tissue with vulvodynia appears normal without infection or skin disease. vulvodynia impacts negatively on a woman's quality of life as it interferes with sexual and daily activities.

the transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

increased sensitivity to cutaneous stimulation due to a diminished threshold or an increased response to stimuli.

a musculomembranous sac along the urinary tract. urine flows from the kidneys into the bladder via the ureters (ureter), and is held there until urination.

shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. they are pliant, tough, and inextensile.

the 10th cranial nerve. the vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).

a question about whether an individual has or had breast sensitivity or tenderness.

a question about whether an individual has or had pain, tenderness or discomfort in their breast.

a question about whether an individual has or had tenderness.

a question about whether an individual has or had any tenderness, discomfort, or pain of the skin in the treatment area.

a question about an individual's assessment of how big a problem breast tenderness or enlargement has been.

a question about how bothered an individual is by tenderness in their breast or chest area.

a question about how bothered an individual is by tenderness in their affected underarm, arm, or hand.

a question about how often an individual has experienced tenderness in their breast area.

a question about often an individual had breast tenderness.

a question about an individual's observation of the worst severity they have experienced related to breast area enlargement or tenderness over the past seven days.

a question about an individual's observation of the worst severity they have experienced related to breast area enlargement or tenderness in the past seven days.

a question about whether an individual experiences or experienced cramping pain in their arm.

a question about whether an individual has or had shooting or burning pain in their fingers or hands.

a question about whether an individual has or had shooting or burning pain in their toes or feet.

a question about whether an individual experiences or experienced stabbing pain in their arm.

a response indicating that an individual has or had a little soreness.

a question about whether an individual is or was bothered by sore muscles.

european organization for the research and treatment of cancer quality of life questionnaire - anal cancer 27 items (eortc qlq-anl27) during the past week: have you had soreness in the areas that have been treated?

european organization for the research and treatment of cancer quality of life questionnaire - breast cancer 42 items (eortc qlq-br42) during the past week: have you had soreness in your mouth?

european organization for the research and treatment of cancer quality of life questionnaire - head and neck cancer phase iv module version 43 items (eortc qlq-h and n43 phase iv module version) during the past week: have you had soreness in your mouth?

a question about the extent to which an individual has or had soreness in their mouth.

a response indicating that an individual has or had extreme soreness.

a question about whether an individual feels or felt pain, soreness, or aches in some areas of their body.

a question about whether an individual has or had vaginal soreness.

a question about whether an individual has or had vulvar soreness.

a question about how much mouth and throat soreness limits or limited an individual's drinking.

a question about how much mouth and throat soreness limits or limited an individual's eating.

a question about how much mouth and throat soreness limits or limited an individual's sleeping.

a question about how much mouth and throat soreness limits or limited an individual's swallowing.

a question about how much mouth and throat soreness limits or limited an individual's talking.

a question about how much mouth and throat soreness limits or limited an individual's tooth brushing.

a question about the amount of mouth and throat soreness that an individual is experiencing or has experienced.

a response indicating that an individual has or had moderate soreness.

achiness of the muscles.

a response indicating that an individual has or had no soreness.

a question about an individual's overall rating of their mouth and throat soreness on a scale of 1 through 10.

a response indicating that an individual has or had quite a lot of soreness.

soreness likert scale

a response of 0 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 1 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 10 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 2 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 3 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 4 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 5 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 6 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 7 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 8 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a response of 9 on a soreness scale that ranges from 0: no soreness to 10: worst possible soreness.

a question about how often an individual has experienced sharp pains in their breast area.

expanded prostate cancer index composite for clinical practice (epic-cp) how big a problem, if any, has each of the following been for you? hot flashes or breast tenderness/enlargement.

functional assessment of chronic illness therapy-searchable item library adult version (facit-searchable item library adult version) i am bothered by mouth sores or tenderness.

functional assessment of chronic illness therapy-searchable item library adult version (facit-searchable item library adult version) i have breast sensitivity/tenderness.

revised fibromyalgia impact questionnaire (fiqr) please rate your level of tenderness to touch.

a question about whether an individual has or had breast sensitivity or tenderness.

a question about whether an individual has or had pain, tenderness or discomfort in their breast.

a question about whether an individual has or had any tenderness, discomfort, or pain of the skin in the treatment area.

a question about whether an individual has or had tenderness.

a question about an individual's assessment of how big a problem breast tenderness or enlargement has been.

a question about how bothered an individual is by tenderness in their breast or chest area.

a question about how bothered an individual is by tenderness in their affected underarm, arm, or hand.

a question about how often an individual has experienced tenderness in their breast area.

a question about often an individual had breast tenderness.

an indication as to whether there are symptoms of motion tenderness.

patient-reported outcomes version of the common terminology criteria for adverse events item library version 1.0 (pro-ctcae v1.0) in the last 7 days, what was the severity of your breast area enlargement or tenderness at its worst?

symptom impact questionnaire (siqr) please rate your level of tenderness to touch.

discomfort elicited through touch or pressure.

an indicator as to whether the subject has symptoms of tenderness.

a question about an individual's observation of the worst severity they have experienced related to breast area enlargement or tenderness over the past seven days.

a question about an individual's observation of the worst severity they have experienced related to breast area enlargement or tenderness in the past seven days.

a sense of discomfort or distress that is spasmodic or clenching.

a question about whether an individual experiences or experienced cramping pain in their arm.

short-form mcgill pain questionnaire-2 (short form mpq) cramping pain.

short-form mcgill pain questionnaire-2 (short form mpq) splitting pain.

an intense sensation of discomfort or distress that feels like being cut apart.

a sense of discomfort or distress that is squeezing or excessively compressing.

the sensation of chest pain described as an intense discomfort, similar to that experience as a result of a thermal burn, distinct from sharp, stabbing or aching, often related to nerves; sometimes used to describe gastric or esophageal pain.

a sensation of intensely hot or searing discomfort.

a question about whether an individual has or had shooting or burning pain in their fingers or hands.

a question about whether an individual has or had shooting or burning pain in their toes or feet.

michigan neuropathy screening instrument (mnsi) history; do you ever have any burning pain in your legs and/or feet?

short-form mcgill pain questionnaire-2 (short form mpq) hot-burning pain.

an event in which the patient reports pain that is severe, uncontrolled, and causing distress for the patient, family members, or both.

short-form mcgill pain questionnaire-2 (short form mpq) shooting pain.

an intense sensation of discomfort or distress that radiates from one location to another sharply.

a question about whether an individual experiences or experienced stabbing pain in their arm.

short-form mcgill pain questionnaire-2 (short form mpq) stabbing pain.

an intense sensation of discomfort or distress that is sharp and feels as though a knife has penetrated an anatomical location.

a question about whether an individual is or was bothered by sore muscles.

a question about the extent to which an individual has or had soreness in their mouth.

functional assessment of chronic illness therapy-searchable item library adult version (facit-searchable item library adult version) i feel pain, soreness or aches in some of my muscles.

a question about whether an individual feels or felt pain, soreness, or aches in some areas of their body.

a question about whether an individual has or had vaginal soreness.

a question about whether an individual has or had vulvar soreness.

kidney disease and quality of life-36 version 1 (kdqol-36 version 1) during the past 4 weeks, to what extent were you bothered by each of the following: soreness in your muscles?

patient health questionnaire screener version (phq screener version) over the last 4 weeks, how often have you been bothered by muscle tension, aches, or soreness?

the tenderness of the breasts during pregnancy due to changes in the hormonal levels and increased breast tissue growth.

a dull achy pain.

the sensation of chest pain described as a mild or blunted discomfort.

a sensation of discomfort or distress that is non-specific or without clear boundaries.

a question about how often an individual has experienced sharp pains in their breast area.

short-form mcgill pain questionnaire-2 (short form mpq) sharp pain.

the sensation of chest pain described as a stabbing feeling.

a sensation of discomfort or distress that is distinct and intensely focused.

a sensation of discomfort or distress that spreads from one anatomic location to another.

breast inflammation as recorded on the pro-ctcae questionnaire.

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Inclusion Terms These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.

Type 1 Excludes

Type 1 Excludes A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

References found for this diagnosis code in the External Cause of Injuries Index:

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 338.19

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

ICD-9-CM: 780.96

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

Pain

What is pain?

Pain is a signal in your nervous system that something may be wrong. It is an unpleasant feeling, such as a prick, tingle, sting, burn, or ache. Each person feels pain differently, even if the reason for the pain is the same. Pain may be sharp or dull. It may be mild or severe. Pain may come and go, or it may be constant. You may feel pain in one area of your body, such as your back, abdomen, chest, or pelvis, or you may feel it all over.

Pain can help alert you that there is a problem. If you never felt pain, you might seriously hurt yourself without knowing it, or you might not realize you have a medical problem that needs treatment. Finding out what's causing your pain will help your health care provider determine the best way to manage or treat it.

What are the types of pain?

Patterns and types of pain are named based on how long and how often you have pain. These include:

Pain may also be categorized by what is likely to be the cause of the pain. Pain may be described as nociceptive (caused by tissue damage or inflammation), neuropathic (caused by nerve damage), or nociplastic (caused by changes in how your nervous system processes pain).

What causes pain?

Understanding what causes pain and why people feel it differently may be difficult. Often, it's easier to find the cause of acute pain due to an injury than the cause of chronic pain, or you may have an ongoing cause of pain, such as cancer.

In some cases, there is no clear cause. Environmental factors and psychological factors such as stress and beliefs about pain may affect the way you feel pain and respond to treatment.

How is pain diagnosed?

You are the only one who knows how your pain feels. Your provider can best measure your pain by how you report it. They may ask you:

If the cause of your pain is unknown, your provider may also do a physical exam and order blood tests or other medical tests to help find the cause.

What are the treatments for pain?

Pain is not always curable, but there are many ways to manage and treat it. Treatment depends on the cause and type of pain. Treatments may include medicines, such as pain relievers. There are also non-drug treatments, such as acupuncture, physical therapy, and sometimes surgery.

Depending on the cause of your pain and your symptoms, your provider may recommend lifestyle changes. These may include suggestions for:

NIH: National Institute of Neurological Disorders and Stroke

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