ICD-10-CM Diagnosis Code R53.1 - Weakness (original) (raw)

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ICD List 2025-2026 Edition

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  6. 2026 ICD-10-CM Code R53.1

Weakness

ICD-10-CM Code:

R53.1

ICD-10 Code for:

Weakness

Is Billable?

Yes - Valid for Submission

Chronic Condition Indicator: [1]

Not chronic

Code Navigator:

R53.1 is a billable diagnosis code used to specify a medical diagnosis of weakness. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

  1. Code Information
  2. Approximate Synonyms
  3. Clinical Classification
  4. Clinical Information
  5. Tabular List of Diseases and Injuries
  6. Index to Diseases and Injuries References
  7. Diagnostic Related Groups Mapping
  8. Convert to ICD-9 Code
  9. Patient Education
  10. Other Codes Used Similar Conditions
  11. Code History

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

CCSR Code: SYM007

Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.

Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.

clinical sign or symptom manifested as debility, or lack or loss of strength and energy.

a clinical syndrome characterized by palpitation, shortness of breath, labored breathing, subjective complaints of effort and discomfort, all following slight physical exertion. other symptoms may be dizziness, tremulousness, sweating, and insomnia. neurocirculatory asthenia is most typically seen as a form of anxiety disorder.

a reduction or absence of vestibular function occurring in both inner ears.

european organization for the research and treatment of cancer quality of life questionnaire - chronic lymphocytic leukemia 17 items (eortc qlq-cll17) have you had muscle weakness?

a question about whether an individual has or had weakness in their arm or hand.

mild symptoms; clinical or diagnostic observations only; intervention not indicated

moderate symptoms; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)

symptomatic; evident on physical exam; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)

symptomatic; evident on physical exam; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)

symptomatic; evident on physical exam; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)

symptomatic; evident on physical exam; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)

symptomatic, not interfering with bladder, bowel, or vaginal function; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)

severe symptoms; limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

severe symptoms; limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

a question about whether an individual has or had difficulty climbing stairs or getting up out of a chair because of weakness in their legs.

a question about whether an individual has or had difficulty opening a jar or bottle because of weakness in their hands.

a question about whether an individual feels or felt unusual weakness.

a question about whether an individual has or had weakness in their legs.

a question about whether an individual has or had weakness in their arms or legs.

a question about whether an individual has or had weakness of both legs.

a question about whether an individual has or had weakness on one side of the body.

a question about how bothered an individual is by arm weakness in their affected arm.

a question about how often an individual has or had experienced difficulty doing everyday activities because of abdominal muscle weakness (e.g.making their bed).

a question about how often an individual has or had experienced difficulty sitting up because of abdominal muscle weakness (e.g.getting out of bed).

a question about an individual's weakness in their arms and/or legs at its worst.

a question about an individual's weakness on one side of the body at its worst.

a reduction in the strength of the eye muscles.

a disorder characterized by a reduction in the strength of the facial muscles.

a reduction in the strength of the facial muscles.

evidence of facial weakness following cerebral infarction.

evidence of facial weakness following other cerebrovascular disease.

evidence of facial weakness following unspecified cerebrovascular disease.

functional assessment of chronic illness therapy-searchable item library adult version (facit-searchable item library adult version) i have weakness in my arms or legs.

functional assessment of chronic illness therapy-searchable item library adult version (facit-searchable item library adult version) i have weakness in my legs.

functional assessment of cancer therapy-brain symptom index (fbrsi) i have weakness in my arms or legs.

a question about whether an individual has or had weakness in their arm or hand.

impairments of brain function, the nerve or spinal cord that affect a specific region of the body.

a disorder characterized by a reduction in the strength of muscles in multiple anatomic sites.

a reduction in the strength of muscles in multiple anatomic sites.

asymptomatic; clinical or diagnostic observations only; intervention not indicated

symptomatic; perceived by patient but not evident on physical exam

symptomatic; perceived by patient but not evident on physical exam

symptomatic; perceived by patient but not evident on physical exam

symptomatic; perceived by patient but not evident on physical exam

symptomatic; perceived by patient but not evident on physical exam

symptomatic; perceived by patient but not evident on physical exam

asymptomatic; clinical or diagnostic observations only; intervention not indicated

moderate symptoms; limiting instrumental adl

symptomatic; evident on physical exam; limiting instrumental adl

symptomatic; evident on physical exam; limiting instrumental adl

symptomatic; evident on physical exam; limiting instrumental adl

symptomatic; evident on physical exam; limiting instrumental adl

symptomatic; evident on physical exam; limiting instrumental adl

symptomatic; evident on physical exam; limiting instrumental adl

symptomatic, not interfering with bladder, bowel, or vaginal function; limiting instrumental adl

severe symptoms; limiting self care adl

limiting self care adl

limiting self care adl

limiting self care adl

limiting self care adl

limiting self care adl

limiting self care adl

severe symptoms; limiting self care adl

a question about whether an individual has or had difficulty climbing stairs or getting up out of a chair because of weakness in their legs.

a question about whether an individual has or had difficulty opening a jar or bottle because of weakness in their hands.

a question about whether an individual feels or felt unusual weakness.

a question about whether an individual has or had weakness in their legs.

a question about whether an individual has or had weakness in their arms or legs.

a question about whether an individual has or had weakness of both legs.

a question about whether an individual has or had weakness on one side of the body.

a question about how bothered an individual is by arm weakness in their affected arm.

a question about how often an individual has or had experienced difficulty doing everyday activities because of abdominal muscle weakness (e.g.making their bed).

a question about how often an individual has or had experienced difficulty sitting up because of abdominal muscle weakness (e.g.getting out of bed).

kurtzke functional systems scores (kfss) record number 1 in small box when weakness (grade 3 or worse on pyramidal) interferes with testing.

kurtzke functional system scores kfss103 original result - severe nystagmus, marked extraocular weakness, or moderate disability of other cranial nerves.

a reduction in the strength of one or more muscles.

a disorder characterized by a reduction in the strength of the muscles on the left side of the body.

a reduction in the strength of the muscles in the left side of the body.

a disorder characterized by a reduction in the strength of the lower limb muscles.

a reduction in the strength of the lower limb muscles.

a disorder characterized by a reduction in the strength of the muscles on the right side of the body.

a reduction in the strength of the muscles in the right side of the body.

a disorder characterized by a reduction in the strength of the trunk muscles.

a reduction in the strength of the trunk muscles.

a disorder characterized by a reduction in the strength of the upper limb muscles.

a reduction in the strength of the upper limb muscles.

a reduction in the strength and/or mass of one or more muscles.

national comprehensive cancer network/functional assessment of cancer therapy-brain symptom index-24 version 2 (nccn-fact fbrsi-24 version 2) i have weakness in my arms or legs.

national comprehensive cancer network/functional assessment of cancer therapy-prostate symptom index 17 version 2 (nccn-fact-fpsi 17 version 2) i have weakness in my legs.

a response indicating that an individual has or had shoulder pain or weakness that has caused a work change.

a disorder characterized by a reduction in the strength of the muscles of the pelvic floor.

a reduction in the strength of the muscles of the pelvic floor.

the property of lacking physical strength.

a question about an individual's weakness in their arms and/or legs at its worst.

a question about an individual's weakness on one side of the body at its worst.

an autosomal recessive condition caused by mutation(s) in the tbcd gene, encoding tubulin-specific chaperone d. it is characterized by encephalopathy, cerebellar and cerebral atrophy, and a thin corpus callosum.

human mt-atp6 wild-type allele is located within the circular mitochondrial (mt) chromosome and is approximately 681 bases in length. this allele, which encodes atp synthase subunit a protein, plays a role in proton-transport and atp synthesis. mutation of the gene is associated with neuropathy, ataxia, and retinitis pigmentosa (narp); leber hereditary optic neuropathy (lhon); leigh syndrome (ls); mitochondrial infantile bilateral striatal necrosis (mibsn); myopathy, lactic acidosis, and sideroblastic anemia 3 (mlasa3); adult-onset ataxia and polyneuropathy (apao); infantile hypertrophic cardiomyopathy (cmhi); and mitochondrial complex v (atp synthase) deficiency mitochondrial type 1 (mc5dm1).

weakness of muscles as recorded on the ped-pro-ctcae questionnaire.

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

References found for this diagnosis code in the External Cause of Injuries Index:

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

ICD-9-CM: 780.79

Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.

Muscle Disorders

Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that can affect muscles. Muscle disorders can cause weakness, pain or even paralysis.

Causes of muscle disorders include:

Sometimes the cause of muscle disorders is unknown.

[Learn More in MedlinePlus]