ICD-10-CM Diagnosis Code R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin (original) (raw)

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ICD List 2025-2026 Edition

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Systemic inflammatory response syndrome (SIRS) of non-infectious origin

ICD-10-CM Code:

R65.1

ICD-10 Code for:

SIRS of non-infectious origin

Is Billable?

Not Valid for Submission

Code Navigator:

R65.1 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity from the list below for a diagnosis of systemic inflammatory response syndrome (sirs) of non-infectious origin. The code is not specific and is NOT valid for the year 2026 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Non-specific codes like R65.1 require more digits to indicate the appropriate level of specificity. Consider using any of the following billable codes with a higher level of specificity when coding for sirs of non-infectious origin:

Use R65.10 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction

Use R65.11 for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

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