ICD-10-CM Diagnosis Code T36.8X5D - Adverse effect of other systemic antibiotics, subsequent encounter (original) (raw)
ICD List 2025-2026 Edition
- Home
- ICD-10-CM Codes
- S00–T88
- T36-T50
- T36
- 2026 ICD-10-CM Code T36.8X5D
Adverse effect of other systemic antibiotics, subsequent encounter
ICD-10-CM Code:
T36.8X5D
ICD-10 Code for:
Adverse effect of other systemic antibiotics, subs encntr
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:
T36.8X5D is a billable diagnosis code used to specify a medical diagnosis of adverse effect of other systemic antibiotics, subsequent encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.
This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.
T36.8X5D is a subsequent encounter code, includes a 7th character and should be used after the patient has completed active treatment for a condition like adverse effect of other systemic antibiotics. According to ICD-10-CM Guidelines a "subsequent encounter" occurs when the patient is receiving routine care for the condition during the healing or recovery phase of treatment. Subsequent diagnosis codes are appropriate during the recovery phase, no matter how many times the patient has seen the provider for this condition. If the provider needs to adjust the patient's care plan due to a setback or other complication, the encounter becomes active again.
- Code Information
- Approximate Synonyms
- Clinical Classification
- Clinical Information
- Coding Guidelines
- Replaced Code
- Tabular List of Diseases and Injuries
- Code Edits
- Diagnostic Related Groups Mapping
- Present on Admission (POA)
- Convert to ICD-9 Code
- Table of Drugs and Chemicals
- Patient Education
- Other Codes Used Similar Conditions
- Code History
- Injury, poisoning and certain other consequences of external causes
S00–T88
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- 4-quinolones adverse reaction
- Acrosoxacin adverse reaction
- Adverse reaction to sulfamethoxazole and/or trimethoprim
- Antituberculous drug adverse reaction
- Capreomycin adverse reaction
- Ciprofloxacin adverse reaction
- Ciprofloxacin corneal deposits
- Clindamycin adverse reaction
- Colistin adverse reaction
- Drug-induced corneal epithelial deposit
- Drug-induced disorder of cornea
- Enoxacin adverse reaction
- Erythroderma caused by drug
- Erythroderma caused by vancomycin
- Fosfomycin adverse reaction
- Fusidic acid adverse reaction
- Lincomycin adverse reaction
- Norfloxacin adverse reaction
- Ofloxacin adverse reaction
- Polymyxin B adverse reaction
- Polymyxins adverse reaction
- Teicoplanin adverse reaction
- Temafloxacin adverse reaction
- Vancomycin adverse reaction
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
CCSR Code: INJ065
Inpatient Default: X - Not applicable.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Capreomycin
cyclic peptide antibiotic similar to viomycin. it is produced by streptomyces capreolus.
Ciprofloxacin
a broad-spectrum antimicrobial carboxyfluoroquinoline.
Clindamycin
an antibacterial agent that is a semisynthetic analog of lincomycin.
Colistin
cyclic polypeptide antibiotic from bacillus colistinus. it is composed of polymyxins e1 and e2 (or colistins a, b, and c) which act as detergents on cell membranes. colistin is less toxic than polymyxin b, but otherwise similar; the methanesulfonate is used orally.
Enoxacin
a broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to nalidixic acid.
Enviomycin
cyclic basic peptide related to viomycin. it is isolated from an induced mutant of streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.
Fleroxacin
a broad-spectrum antimicrobial fluoroquinolone. the drug strongly inhibits the dna-supercoiling activity of dna gyrase.
Fosfomycin
an antibiotic produced by streptomyces fradiae.
Fusidic Acid
an antibiotic isolated from the fermentation broth of fusidium coccineum. (from merck index, 11th ed). it acts by inhibiting translocation during protein synthesis.
Lincomycin
an antibiotic produced by streptomyces lincolnensis var. lincolnensis. it has been used in the treatment of staphylococcal, streptococcal, and bacteroides fragilis infections.
Norfloxacin
a synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. norfloxacin inhibits bacterial dna gyrase.
Levofloxacin
the l-isomer of ofloxacin.
Ofloxacin
a synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial dna gyrase, halting dna replication.
Ristocetin
an antibiotic mixture of two components, a and b, obtained from nocardia lurida (or the same substance produced by any other means). it is no longer used clinically because of its toxicity. it causes platelet agglutination and blood coagulation and is used to assay those functions in vitro.
von Willebrand Factor
a high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor viii/von willebrand factor complex. the von willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. it functions in adhesion of platelets to collagen and hemostatic plug formation. the prolonged bleeding time in von willebrand diseases is due to the deficiency of this factor.
Teicoplanin
lipoglycopeptide antibiotic from actinoplanes teichomyceticus active against gram-positive bacteria. it consists of five major components each with a different fatty acid moiety.
Vancomycin
antibacterial obtained from streptomyces orientalis. it is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
Vancomycin Resistance
nonsusceptibility of bacteria to the action of vancomycin, an inhibitor of cell wall synthesis.
Vancomycin-Resistant Enterococci
strains of the genus enterococcus that are resistant to the antibiotic vancomycin. the enterococci become resistant by acquiring plasmids carrying genes for vancomycin resistance.
Vancomycin-Resistant Staphylococcus aureus
isolates of the staphylococcus aureus that are resistant to the antibiotic vancomycin. the s. aureus becomes resistant by acquiring plasmids carrying genes for vancomycin resistance. vancomycin‐intermediate s. aureus has low-level vancomycin resistance requiring an intermediate concentration of vancomycin between sensitive and resistant isolates. these s. aureus with reduced susceptibility to vancomycin and related glycopeptide antibiotics are often seen in healthcare associated infections.
Viomycin
a strongly basic peptide, antibiotic complex from several strains of streptomyces. it is allergenic and toxic to kidneys and the labyrinth. viomycin is used in tuberculosis as several different salts and in combination with other agents.
Streptogramin A
a specific streptogramin group a antibiotic produced by streptomyces graminofaciens and other bacteria.
Virginiamycin
a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. loidensis, s. mitakaensis, s. pristina-spiralis, s. ostreogriseus, and others. it consists of 2 major components, virginiamycin factor m1 and virginiamycin factor s1. it is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
This code was replaced in the 2026 ICD-10-CM code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This code was replaced for the FY 2026 (October 1, 2025 - September 30, 2026).
- T36.AX5D - Adverse effect of fluoroquinolone antibiotics, subs
- T36.AX5D - Adverse effect of fluoroquinolone antibiotics, subs
The Medicare Code Editor (MCE) detects errors and inconsistencies in ICD-10-CM diagnosis coding that can affect Medicare claim validity. These Medicare code edits help medical coders and billing professionals determine when a diagnosis code is not appropriate as a principal diagnosis, does not meet coverage criteria. Use this list to verify whether a code is valid for Medicare billing and to avoid claim rejections or denials due to diagnosis coding issues.
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.
T36.8X5D is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.
CMS POA Indicator Options and Definitions
POA Indicator: Y
Reason: Diagnosis was present at time of inpatient admission.
CMS Pays CC/MCC DRG? YES
POA Indicator: N
Reason: Diagnosis was not present at time of inpatient admission.
CMS Pays CC/MCC DRG? NO
POA Indicator: U
Reason: Documentation insufficient to determine if the condition was present at the time of inpatient admission.
CMS Pays CC/MCC DRG? NO
POA Indicator: W
Reason: Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.
CMS Pays CC/MCC DRG? YES
POA Indicator: 1
Reason: Unreported/Not used - Exempt from POA reporting.
CMS Pays CC/MCC DRG? NO
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
ICD-9-CM: V58.89
Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.
The parent code T36.8X5 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Filter table of drugs and chemicals:
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
What is a drug interaction?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:
- Two drugs, such as aspirin and blood thinners
- Drugs and food, such as statins and grapefruit
- Drugs and supplements, such as gingko and blood thinners
- Drugs and medical conditions, such as aspirin and peptic ulcers
Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.
What are side effects?
Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.
What are drug allergies?
Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.
How can I stay safe when taking medicines?
When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.
FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026
FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025
FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.