ICD-10-CM Diagnosis Code T65.842S - Toxic effect of xylazine, intentional self-harm, sequela (original) (raw)

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ICD List 2025-2026 Edition

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  6. 2026 ICD-10-CM Code T65.842S

Toxic effect of xylazine, intentional self-harm, sequela

ICD-10-CM Code:

T65.842S

ICD-10 Code for:

Toxic effect of xylazine, intentional self-harm, sequela

Is Billable?

Yes - Valid for Submission

Code Navigator:

T65.842S is a billable diagnosis code used to specify a medical diagnosis of toxic effect of xylazine, intentional self-harm, sequela. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

T65.842S is a sequela code, includes a 7th character and should be used for complications that arise as a direct result of a condition like toxic effect of xylazine intentional self-harm. According to ICD-10-CM Guidelines a "sequela" code should be used for chronic or residual conditions that are complications of an initial acute disease, illness or injury. The most common sequela is pain. Usually, two diagnosis codes are needed when reporting sequela. The first code describes the nature of the sequela while the second code describes the sequela or late effect.

  1. Code Information
  2. Clinical Information
  3. Coding Guidelines
  4. 2026 ICD-10 Code
  5. Tabular List of Diseases and Injuries
  6. Diagnostic Related Groups Mapping
  7. Present on Admission (POA)
  8. Replacement Code
  9. Table of Drugs and Chemicals
  10. Patient Education
  11. Other Codes Used Similar Conditions
  12. Code History

an adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in veterinary medicine.

The appropriate 7th character is to be added to each code from block Toxic effect of other and unspecified substances (T65). Use the following options for the aplicable episode of care:

T65.842S is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

T65.842S is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA Indicator: Y

Reason: Diagnosis was present at time of inpatient admission.

CMS Pays CC/MCC DRG? YES

POA Indicator: N

Reason: Diagnosis was not present at time of inpatient admission.

CMS Pays CC/MCC DRG? NO

POA Indicator: U

Reason: Documentation insufficient to determine if the condition was present at the time of inpatient admission.

CMS Pays CC/MCC DRG? NO

POA Indicator: W

Reason: Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.

CMS Pays CC/MCC DRG? YES

POA Indicator: 1

Reason: Unreported/Not used - Exempt from POA reporting.

CMS Pays CC/MCC DRG? NO

T65842S replaces the following previously assigned ICD-10-CM code(s):

The parent code T65.842 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Filter table of drugs and chemicals:

Substance Poisoning Accidental (unintentional) Poisoning Accidental (self-harm) Poisoning Assault Poisoning Undetermined Adverse effect Underdosing
Xylazine T65.841 T65.842 T65.843 T65.844