Andy Rimando | The University of Scranton (original) (raw)
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The purpose of this study is to provide evidence-based comparison between inhalational anesthesia... more The purpose of this study is to provide evidence-based comparison between inhalational anesthesia and total intravenous anesthesia in patients undergoing thoracic surgery with one lung ventilation (OLV), and determine their impact on hemodynamics, inflammatory responses, and adverse events. During OLV, one lung is deliberately isolated and ventilated, while the other lung remains unventilated and exposed to surgery. Anesthesia is maintained by inhalational or intravenous agents, which can induce inflammatory mediators, impair hypoxic pulmonary vasoconstriction, and cause hypoxemia. Electronic search of databases was accomplished by search terms “one lung ventilation,” “inhalational anesthetics,” “intravenous anesthetics,” “and “hypoxic pulmonary vasoconstriction.” Nine randomized controlled trials were finally retained for review of evidence. Analysis of findings failed to indicate superiority of one anesthetic technique over another in attenuating or worsening patients’ hemodynamic instability or hypoxia during OLV procedures. Due to insufficient evidence, change in practice cannot be advised. The need for further research is merited.
This literature review is an attempt to gain more insight to the recent studies about permissive ... more This literature review is an attempt to gain more insight to the recent studies about permissive hypotension as an alternative to the current adult trauma protocols. It will try answer whether permissive hypotension is beneficial or not to a bleeding trauma patient based on available literature and clinical and laboratory research. It will also attempt to discuss its limitations in the clinical setting. As such, it contains the review of several current and seminal studies on permissive hypotension strategies in managing bleeding adult trauma patients
The purpose of this study is to provide evidence-based comparison between inhalational anesthesia... more The purpose of this study is to provide evidence-based comparison between inhalational anesthesia and total intravenous anesthesia in patients undergoing thoracic surgery with one lung ventilation (OLV), and determine their impact on hemodynamics, inflammatory responses, and adverse events. During OLV, one lung is deliberately isolated and ventilated, while the other lung remains unventilated and exposed to surgery. Anesthesia is maintained by inhalational or intravenous agents, which can induce inflammatory mediators, impair hypoxic pulmonary vasoconstriction, and cause hypoxemia. Electronic search of databases was accomplished by search terms “one lung ventilation,” “inhalational anesthetics,” “intravenous anesthetics,” “and “hypoxic pulmonary vasoconstriction.” Nine randomized controlled trials were finally retained for review of evidence. Analysis of findings failed to indicate superiority of one anesthetic technique over another in attenuating or worsening patients’ hemodynamic instability or hypoxia during OLV procedures. Due to insufficient evidence, change in practice cannot be advised. The need for further research is merited.
This literature review is an attempt to gain more insight to the recent studies about permissive ... more This literature review is an attempt to gain more insight to the recent studies about permissive hypotension as an alternative to the current adult trauma protocols. It will try answer whether permissive hypotension is beneficial or not to a bleeding trauma patient based on available literature and clinical and laboratory research. It will also attempt to discuss its limitations in the clinical setting. As such, it contains the review of several current and seminal studies on permissive hypotension strategies in managing bleeding adult trauma patients