Krishna Kumar Perikamana | Indian Institute for Human Settlements (original) (raw)

Papers by Krishna Kumar Perikamana

Research paper thumbnail of A CNN based method for Sub-pixel Urban Land Cover Classification using Landsat-5 TM and Resourcesat-1 LISS-IV Imagery

ArXiv, 2021

Time series data of urban land cover is of great utility in analyzing urban growth patterns, chan... more Time series data of urban land cover is of great utility in analyzing urban growth patterns, changes in distribution of impervious surface and vegetation and resulting impacts on urban micro climate. While Landsat data is ideal for such analysis due to the long time series of free imagery, traditional per-pixel hard classification fails to yield full potential of the Landsat data. This paper proposes a sub-pixel classification method that leverages the temporal overlap of Landsat-5 TM and Resourcesat-1 LISS-IV sensors. We train a convolutional neural network to predict fractional land cover maps from 30m Landsat-5 TM data. The reference land cover fractions are estimated from a hardclassified 5.8m LISS-IV image for Bengaluru from 2011. Further, we demonstrate the generalizability and superior performance of the proposed model using data for Mumbai from 2009 and comparing it to the results obtained using a Random Forest classifier. For both Bengaluru (2011) and Mumbai (2009) data, Me...

Research paper thumbnail of State-of-the-art review on automated lumen and adventitial border delineation and its measurements in carotid ultrasound

Computer methods and programs in biomedicine, 2018

Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carot... more Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the plaque burden can be predicted using the automated carotid lumen diameter (LD)/inter-adventitial diameter (IAD) measurements from B-mode ultrasound images. The objective of this review is to present the state-of-the-art methods and systems for the measurement of LD/IAD in CCA based on automated or semi-automated strategies. Further, the performance of these systems is compared based on various metrics for its measurements. The automated algorithms proposed for the segmentation of carotid lumen are broadly classified into two different categories as: region-based and boundary-based. These techniques are discussed in detail specifying their pros and cons. Further, we discuss the challenges encounte...

Research paper thumbnail of A semi-automatic method for carotid artery wall segmentation in MR images

2016 IEEE Annual India Conference (INDICON), 2016

The quantification of carotid artery stenosis via imaging techniques guides the physicians to tak... more The quantification of carotid artery stenosis via imaging techniques guides the physicians to take a decision regarding surgical interventions. The measurement of wall thickness from magnetic resonance (MR) images is a promising approach to measure the degree of carotid stenosis. Manual tracing of the carotid vessel walls is time consuming and is sensitive to observer variability. Further, the existing segmentation techniques are limited by the poor contrast and presence of noise in MR images. The objective this paper is to present a novel segmentation strategy for carotid lumen and outer wall from MR images. The segmentation has been carried out in two stages which starts with a user assisted region of interest selection. In the first stage, an active contour based global segmentation has been applied to classify the lumen region. In the second stage, morphological gradient of the region of interest has been computed. This is followed by particle swarm optimization based localized segmentation to separate the wall region. The results demonstrate excellent correspondence between the automatic and manual tracings for lumen and outer walls of the carotid artery.

Research paper thumbnail of Two Automated Techniques for Carotid Lumen Diameter Measurement: Regional versus Boundary Approaches

Journal of medical systems, 2016

The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diame... more The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diameter (LD) measured from B-mode ultrasound images. Systolic velocity-based methods for measurement of LD are subjective. With the advancement of high resolution imaging, image-based methods have started to emerge. However, they require robust image analysis for accurate LD measurement. This paper presents two different algorithms for automated segmentation of the lumen borders in carotid ultrasound images. Both algorithms are modeled as a two stage process. Stage one consists of a global-based model using scale-space framework for the extraction of the region of interest. This stage is common to both algorithms. Stage two is modeled using a local-based strategy that extracts the lumen interfaces. At this stage, the algorithm-1 is modeled as a region-based strategy using a classification framework, whereas the algorithm-2 is modeled as a boundary-based approach that uses the level set frame...

Research paper thumbnail of Magnetic resonance image denoising using nonlocal maximum likelihood paradigm in DCT-framework

International Journal of Imaging Systems and Technology, 2015

The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that... more The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that has its origin in the thermal Brownian motion of electrons. Denoising can enhance the quality (by improving the SNR) of the acquired MR image, which is important for both visual analysis and other post processing operations. Recent works on maximum likelihood (ML) based denoising shows that ML methods are very effective in denoising MR images and has an edge over the other state‐of‐the‐art methods for MRI denoising. Among the ML based approaches, the Nonlocal maximum likelihood (NLML) method is commonly used. In the conventional NLML method, the samples for the ML estimation of the unknown true pixel are chosen in a nonlocal fashion based on the intensity similarity of the pixel neighborhoods. Euclidean distance is generally used to measure this similarity. It has been recently shown that computing similarity measure is more robust in discrete cosine transform (DCT) subspace, compared with Euclidean image subspace. Motivated by this observation, we integrated DCT into NLML to produce an improved MRI filtration process. Other than improving the SNR, the time complexity of the conventional NLML can also be significantly reduced through the proposed approach. On synthetic MR brain image, an average improvement of 5% in PSNR and 86%reduction in execution time is achieved with a search window size of 91 × 91 after incorporating the improvements in the existing NLML method. On an experimental kiwi fruit image an improvement of 10% in PSNR is achieved. We did experiments on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 256–264, 2015

Research paper thumbnail of A Review on Carotid Ultrasound Atherosclerotic Tissue Characterization and Stroke Risk Stratification in Machine Learning Framework

Current atherosclerosis reports, 2015

Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause o... more Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause of death in today's world. However, very little is understood about the arterial mechanics of plaque buildup, arterial fibrous cap rupture, and the role of abnormalities of the vasa vasorum. Recently, ultrasonic echogenicity characteristics and morphological characterization of carotid plaque types have been shown to have clinical utility in classification of stroke risks. Furthermore, this characterization supports aggressive and intensive medical therapy as well as procedures, including endarterectomy and stenting. This is the first state-of-the-art review to provide a comprehensive understanding of the field of ultrasonic vascular morphology tissue characterization. This paper presents fundamental and advanced ultrasonic tissue characterization and feature extraction methods for analyzing plaque. Additionally, the paper shows how the risk stratification is achieved using machine le...

Research paper thumbnail of A hybrid method for object identification and event detection in video

2013 Fourth National Conference on Computer Vision, Pattern Recognition, Image Processing and Graphics (NCVPRIPG), 2013

Video event detection (VED) is a challenging task especially with a large variety of objects in t... more Video event detection (VED) is a challenging task especially with a large variety of objects in the environment. Even though there exist numerous algorithms for event detection, most of them are unsuitable for a typical consumer purpose. A hybrid method for detecting and identifying the moving objects by their color and spatial information is presented in this paper. In tracking multiple moving objects, the system makes use of motion of changed regions. In this approach, first, the object detector will look for the existence of objects that have already been registered. Then the control is passed on to an event detector which will wait for an event to happen which can be object placement or object removal. The object detector becomes active only if any event is detected. Simple training procedure using a single color camera in HSV color space makes it a consumer application. The proposed model has proved to be robust in various indoor environments and different types of background scenes. The experimental results prove the feasibility of the proposed method.

Research paper thumbnail of Accurate lumen diameter measurement in curved vessels in carotid ultrasound: an iterative scale-space and spatial transformation approach

Medical & biological engineering & computing, Jan 10, 2016

Monitoring of cerebrovascular diseases via carotid ultrasound has started to become a routine. Th... more Monitoring of cerebrovascular diseases via carotid ultrasound has started to become a routine. The measurement of image-based lumen diameter (LD) or inter-adventitial diameter (IAD) is a promising approach for quantification of the degree of stenosis. The manual measurements of LD/IAD are not reliable, subjective and slow. The curvature associated with the vessels along with non-uniformity in the plaque growth poses further challenges. This study uses a novel and generalized approach for automated LD and IAD measurement based on a combination of spatial transformation and scale-space. In this iterative procedure, the scale-space is first used to get the lumen axis which is then used with spatial image transformation paradigm to get a transformed image. The scale-space is then reapplied to retrieve the lumen region and boundary in the transformed framework. Then, inverse transformation is applied to display the results in original image framework. Two hundred and two patients' le...

Research paper thumbnail of Two Automated Techniques for Carotid Lumen Diameter Measurement: Regional versus Boundary Approaches

Journal of Medical Systems, 2016

The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diame... more The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diameter (LD) measured from B-mode ultrasound images. Systolic velocity-based methods for measurement of LD are subjective. With the advancement of high resolution imaging, image-based methods have started to emerge. However, they require robust image analysis for accurate LD measurement. This paper presents two different algorithms for automated segmentation of the lumen borders in carotid ultrasound images. Both algorithms are modeled as a two stage process. Stage one consists of a global-based model using scale-space framework for the extraction of the region of interest. This stage is common to both algorithms. Stage two is modeled using a local-based strategy that extracts the lumen interfaces. At this stage, the algorithm-1 is modeled as a region-based strategy using a classification framework, whereas the algorithm-2 is modeled as a boundary-based approach that uses the level set framework. Two sets of databases (DB), Japan DB (JDB) (202 patients, 404 images) and Hong Kong DB (HKDB) (50 patients , 300 images) were used in this study. Two trained neu-roradiologists performed manual LD tracings. The mean automated LD measured was 6.35 ± 0.95 mm for JDB and 6.20 ± 1.35 mm for HKDB. The precision-of-merit was: 97.4 % and 98.0 % w.r.t to two manual tracings for JDB and 99.7 % and 97.9 % w.r.t to two manual tracings for HKDB. Statistical tests such as ANOVA, Chi-Squared, T-test, and Mann-Whitney test were conducted to show the stability and reliability of the automated techniques.

Research paper thumbnail of A Review on Carotid Ultrasound Atherosclerotic Tissue Characterization and Stroke Risk Stratification in Machine Learning Framework

Current Atherosclerotic Reports, 2015

Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause o... more Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause of death in today's world. However, very little is understood about the arterial mechanics of plaque buildup, arterial fibrous cap rupture, and the role of abnormalities of the vasa vasorum. Recently, ultrasonic echogenicity characteristics and morphological characterization of carotid plaque types have been shown to have clinical utility in classification of stroke risks. Furthermore, this characterization supports aggressive and intensive medical therapy as well as procedures, including end-arterectomy and stenting. This is the first state-of-the-art review to provide a comprehensive understanding of the field of ultrasonic vascular morphology tissue characterization. This paper presents fundamental and advanced ultrasonic tissue characterization and feature extraction methods for analyzing plaque. Additionally, the paper shows how the risk stratifica-tion is achieved using machine learning paradigms. More advanced methods need to be developed which can segment the carotid artery walls into multiple regions such as the bulb region and areas both proximal and distal to the bulb. Furthermore, multimodality imaging is needed for validation of such advanced methods for stroke and cardiovascular risk stratification.

Research paper thumbnail of Magnetic Resonance Image Denoising Using Nonlocal Maximum Likelihood Paradigm in DCT-Framework

Wiley, 2015

The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that... more The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that has its origin in the thermal Brownian motion of electrons. Denoising can enhance the quality (by improving the SNR) of the acquired MR image, which is important for both visual analysis and other post processing operations. Recent works on maximum likelihood (ML) based denoising shows that ML methods are very effective in denoising MR images and has an edge over the other state-of-the-art methods for MRI denoising. Among the ML based approaches, the Nonlocal maximum likelihood (NLML) method is commonly used. In the conventional NLML method, the samples for the ML estimation of the unknown true pixel are chosen in a nonlocal fashion based on the intensity similarity of the pixel neighborhoods. Euclidean distance is generally used to measure this similarity. It has been recently shown that computing similarity measure is more robust in discrete cosine transform (DCT) subspace, compared with Euclidean image subspace. Motivated by this observation , we integrated DCT into NLML to produce an improved MRI filtration process. Other than improving the SNR, the time complexity of the conventional NLML can also be significantly reduced through the proposed approach. On synthetic MR brain image, an average improvement of 5% in PSNR and 86%reduction in execution time is achieved with a search window size of 91 3 91 after incorporating the improvements in the existing NLML method. On an experimental kiwi fruit image an improvement of 10% in PSNR is achieved. We did experiments on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method.

Research paper thumbnail of Accurate lumen diameter measurement in curved vessels in carotid ultrasound an iterative scale‑space and spatial transformation approach

Medical Biological Engineering and Computing, 2016

Monitoring of cerebrovascular diseases via carotid ultrasound has started to become a routine. Th... more Monitoring of cerebrovascular diseases via carotid
ultrasound has started to become a routine. The measurement
of image-based lumen diameter (LD) or inter-adventitial
diameter (IAD) is a promising approach for quantification of
the degree of stenosis. The manual measurements of LD/IAD
are not reliable, subjective and slow. The curvature associated
with the vessels along with non-uniformity in the plaque growth
poses further challenges. This study uses a novel and generalized
approach for automated LD and IAD measurement based
on a combination of spatial transformation and scale-space. In
this iterative procedure, the scale-space is first used to get the
lumen axis which is then used with spatial image transformation
paradigm to get a transformed image. The scale-space is
then reapplied to retrieve the lumen region and boundary in the
transformed framework. Then, inverse transformation is applied
to display the results in original image framework. Two hundred
and two patients’ left and right common carotid artery (404
carotid images) B-mode ultrasound images were retrospectively analyzed. The validation of our algorithm has done against
the two manual expert tracings. The coefficient of correlation
between the two manual tracings for LD was 0.98 (p < 0.0001)
and 0.99 (p < 0.0001), respectively. The precision of merit
between the manual expert tracings and the automated system
was 97.7 and 98.7%, respectively. The experimental analysis
demonstrated superior performance of the proposed method
over conventional approaches. Several statistical tests demonstrated
the stability and reliability of the automated system.

Research paper thumbnail of State-of-the-art review on automated lumen and adventitial border delineation and its measurements in carotid ultrasound

Computer Methods and Programs in Biomedicine, 2018

Background and objective: Accurate, reliable, efficient, and precise measurements of the lumen ge... more Background and objective: Accurate, reliable, efficient, and precise measurements of the lumen geom- etry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the plaque burden can be predicted using the automated carotid lumen diameter (LD)/inter- adventitial diameter (IAD) measurements from B-mode ultrasound images. The objective of this review is to present the state-of-the-art methods and systems for the measurement of LD/IAD in CCA based on automated or semi-automated strategies. Further, the performance of these systems is compared based on various metrics for its measurements. Methods: The automated algorithms proposed for the segmentation of carotid lumen are broadly classi- fied into two different categories as: region-based and boundary-based. These techniques are discussed in detail specifying their pros and cons. Further, we discuss the challenges encountered in the segmen- tation process along with its quantitative assessment. Lastly, we present stenosis quantification and risk stratification strategies. Results: Even though, we have found more boundary-based approaches compared to region-based ap- proaches in the literature, however, the region-based strategy yield more satisfactory performance. Novel risk stratification strategies are presented. On a patient database containing 203 patients, 9 patients are identified as high risk patients, whereas 27 patients are identified as medium risk patients. Conclusions: We have presented different techniques for the lumen segmentation of the common carotid artery from B-mode ultrasound images and measurement of lumen diameter and inter-adventitial di- ameter. We believe that the issue regarding boundary-based techniques can be compensated by taking regional statistics embedded with boundary-based information.

Conference Presentations by Krishna Kumar Perikamana

Research paper thumbnail of A Semi-automatic Method for Carotid Artery Wall Segmentation in MR Images

IEEE, 2016

The quantification of carotid artery stenosis via imaging techniques guides the physicians to tak... more The quantification of carotid artery stenosis via imaging techniques guides the physicians to take a decision regarding surgical interventions. The measurement of wall thickness from magnetic resonance (MR) images is a promising approach to measure the degree of carotid stenosis. Manual tracing of the carotid vessel walls is time consuming and is sensitive to observer variability. Further, the existing segmen-tation techniques are limited by the poor contrast and presence of noise in MR images. The objective this paper is to present a novel segmentation strategy for carotid lumen and outer wall from MR images. The segmentation has been carried out in two stages which starts with a user assisted region of interest selection. In the first stage, an active contour based global segmentation has been applied to classify the lumen region. In the second stage, morphological gradient of the region of interest has been computed. This is followed by particle swarm optimization based localized segmentation to separate the wall region. The results demonstrate excellent correspondence between the automatic and manual tracings for lumen and outer walls of the carotid artery.

Research paper thumbnail of A Hybrid Method for Object Identification and Event Detection in Video

IEEE, 2013

Video event detection (VED) is a challenging task especially with a large variety of objects in t... more Video event detection (VED) is a challenging task especially with a large variety of objects in the environment. Even though there exist numerous algorithms for event detection, most of them are unsuitable for a typical consumer purpose. A hybrid method for detecting and identifying the moving objects by their color and spatial information is presented in this paper. In tracking multiple moving objects, the system makes use of motion of changed regions. In this approach, first, the object detector will look for the existence of objects that have already been registered. Then the control is passed on to an event detector which will wait for an event to happen which can be object placement or object removal. The object detector becomes active only if any event is detected. Simple training procedure using a single color camera in HSV color space makes it a consumer application. The proposed model has proved to be robust in various indoor environments and different types of background scenes. The experimental results prove the feasibility of the proposed method.

Research paper thumbnail of A CNN based method for Sub-pixel Urban Land Cover Classification using Landsat-5 TM and Resourcesat-1 LISS-IV Imagery

ArXiv, 2021

Time series data of urban land cover is of great utility in analyzing urban growth patterns, chan... more Time series data of urban land cover is of great utility in analyzing urban growth patterns, changes in distribution of impervious surface and vegetation and resulting impacts on urban micro climate. While Landsat data is ideal for such analysis due to the long time series of free imagery, traditional per-pixel hard classification fails to yield full potential of the Landsat data. This paper proposes a sub-pixel classification method that leverages the temporal overlap of Landsat-5 TM and Resourcesat-1 LISS-IV sensors. We train a convolutional neural network to predict fractional land cover maps from 30m Landsat-5 TM data. The reference land cover fractions are estimated from a hardclassified 5.8m LISS-IV image for Bengaluru from 2011. Further, we demonstrate the generalizability and superior performance of the proposed model using data for Mumbai from 2009 and comparing it to the results obtained using a Random Forest classifier. For both Bengaluru (2011) and Mumbai (2009) data, Me...

Research paper thumbnail of State-of-the-art review on automated lumen and adventitial border delineation and its measurements in carotid ultrasound

Computer methods and programs in biomedicine, 2018

Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carot... more Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the plaque burden can be predicted using the automated carotid lumen diameter (LD)/inter-adventitial diameter (IAD) measurements from B-mode ultrasound images. The objective of this review is to present the state-of-the-art methods and systems for the measurement of LD/IAD in CCA based on automated or semi-automated strategies. Further, the performance of these systems is compared based on various metrics for its measurements. The automated algorithms proposed for the segmentation of carotid lumen are broadly classified into two different categories as: region-based and boundary-based. These techniques are discussed in detail specifying their pros and cons. Further, we discuss the challenges encounte...

Research paper thumbnail of A semi-automatic method for carotid artery wall segmentation in MR images

2016 IEEE Annual India Conference (INDICON), 2016

The quantification of carotid artery stenosis via imaging techniques guides the physicians to tak... more The quantification of carotid artery stenosis via imaging techniques guides the physicians to take a decision regarding surgical interventions. The measurement of wall thickness from magnetic resonance (MR) images is a promising approach to measure the degree of carotid stenosis. Manual tracing of the carotid vessel walls is time consuming and is sensitive to observer variability. Further, the existing segmentation techniques are limited by the poor contrast and presence of noise in MR images. The objective this paper is to present a novel segmentation strategy for carotid lumen and outer wall from MR images. The segmentation has been carried out in two stages which starts with a user assisted region of interest selection. In the first stage, an active contour based global segmentation has been applied to classify the lumen region. In the second stage, morphological gradient of the region of interest has been computed. This is followed by particle swarm optimization based localized segmentation to separate the wall region. The results demonstrate excellent correspondence between the automatic and manual tracings for lumen and outer walls of the carotid artery.

Research paper thumbnail of Two Automated Techniques for Carotid Lumen Diameter Measurement: Regional versus Boundary Approaches

Journal of medical systems, 2016

The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diame... more The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diameter (LD) measured from B-mode ultrasound images. Systolic velocity-based methods for measurement of LD are subjective. With the advancement of high resolution imaging, image-based methods have started to emerge. However, they require robust image analysis for accurate LD measurement. This paper presents two different algorithms for automated segmentation of the lumen borders in carotid ultrasound images. Both algorithms are modeled as a two stage process. Stage one consists of a global-based model using scale-space framework for the extraction of the region of interest. This stage is common to both algorithms. Stage two is modeled using a local-based strategy that extracts the lumen interfaces. At this stage, the algorithm-1 is modeled as a region-based strategy using a classification framework, whereas the algorithm-2 is modeled as a boundary-based approach that uses the level set frame...

Research paper thumbnail of Magnetic resonance image denoising using nonlocal maximum likelihood paradigm in DCT-framework

International Journal of Imaging Systems and Technology, 2015

The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that... more The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that has its origin in the thermal Brownian motion of electrons. Denoising can enhance the quality (by improving the SNR) of the acquired MR image, which is important for both visual analysis and other post processing operations. Recent works on maximum likelihood (ML) based denoising shows that ML methods are very effective in denoising MR images and has an edge over the other state‐of‐the‐art methods for MRI denoising. Among the ML based approaches, the Nonlocal maximum likelihood (NLML) method is commonly used. In the conventional NLML method, the samples for the ML estimation of the unknown true pixel are chosen in a nonlocal fashion based on the intensity similarity of the pixel neighborhoods. Euclidean distance is generally used to measure this similarity. It has been recently shown that computing similarity measure is more robust in discrete cosine transform (DCT) subspace, compared with Euclidean image subspace. Motivated by this observation, we integrated DCT into NLML to produce an improved MRI filtration process. Other than improving the SNR, the time complexity of the conventional NLML can also be significantly reduced through the proposed approach. On synthetic MR brain image, an average improvement of 5% in PSNR and 86%reduction in execution time is achieved with a search window size of 91 × 91 after incorporating the improvements in the existing NLML method. On an experimental kiwi fruit image an improvement of 10% in PSNR is achieved. We did experiments on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 256–264, 2015

Research paper thumbnail of A Review on Carotid Ultrasound Atherosclerotic Tissue Characterization and Stroke Risk Stratification in Machine Learning Framework

Current atherosclerosis reports, 2015

Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause o... more Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause of death in today's world. However, very little is understood about the arterial mechanics of plaque buildup, arterial fibrous cap rupture, and the role of abnormalities of the vasa vasorum. Recently, ultrasonic echogenicity characteristics and morphological characterization of carotid plaque types have been shown to have clinical utility in classification of stroke risks. Furthermore, this characterization supports aggressive and intensive medical therapy as well as procedures, including endarterectomy and stenting. This is the first state-of-the-art review to provide a comprehensive understanding of the field of ultrasonic vascular morphology tissue characterization. This paper presents fundamental and advanced ultrasonic tissue characterization and feature extraction methods for analyzing plaque. Additionally, the paper shows how the risk stratification is achieved using machine le...

Research paper thumbnail of A hybrid method for object identification and event detection in video

2013 Fourth National Conference on Computer Vision, Pattern Recognition, Image Processing and Graphics (NCVPRIPG), 2013

Video event detection (VED) is a challenging task especially with a large variety of objects in t... more Video event detection (VED) is a challenging task especially with a large variety of objects in the environment. Even though there exist numerous algorithms for event detection, most of them are unsuitable for a typical consumer purpose. A hybrid method for detecting and identifying the moving objects by their color and spatial information is presented in this paper. In tracking multiple moving objects, the system makes use of motion of changed regions. In this approach, first, the object detector will look for the existence of objects that have already been registered. Then the control is passed on to an event detector which will wait for an event to happen which can be object placement or object removal. The object detector becomes active only if any event is detected. Simple training procedure using a single color camera in HSV color space makes it a consumer application. The proposed model has proved to be robust in various indoor environments and different types of background scenes. The experimental results prove the feasibility of the proposed method.

Research paper thumbnail of Accurate lumen diameter measurement in curved vessels in carotid ultrasound: an iterative scale-space and spatial transformation approach

Medical & biological engineering & computing, Jan 10, 2016

Monitoring of cerebrovascular diseases via carotid ultrasound has started to become a routine. Th... more Monitoring of cerebrovascular diseases via carotid ultrasound has started to become a routine. The measurement of image-based lumen diameter (LD) or inter-adventitial diameter (IAD) is a promising approach for quantification of the degree of stenosis. The manual measurements of LD/IAD are not reliable, subjective and slow. The curvature associated with the vessels along with non-uniformity in the plaque growth poses further challenges. This study uses a novel and generalized approach for automated LD and IAD measurement based on a combination of spatial transformation and scale-space. In this iterative procedure, the scale-space is first used to get the lumen axis which is then used with spatial image transformation paradigm to get a transformed image. The scale-space is then reapplied to retrieve the lumen region and boundary in the transformed framework. Then, inverse transformation is applied to display the results in original image framework. Two hundred and two patients' le...

Research paper thumbnail of Two Automated Techniques for Carotid Lumen Diameter Measurement: Regional versus Boundary Approaches

Journal of Medical Systems, 2016

The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diame... more The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diameter (LD) measured from B-mode ultrasound images. Systolic velocity-based methods for measurement of LD are subjective. With the advancement of high resolution imaging, image-based methods have started to emerge. However, they require robust image analysis for accurate LD measurement. This paper presents two different algorithms for automated segmentation of the lumen borders in carotid ultrasound images. Both algorithms are modeled as a two stage process. Stage one consists of a global-based model using scale-space framework for the extraction of the region of interest. This stage is common to both algorithms. Stage two is modeled using a local-based strategy that extracts the lumen interfaces. At this stage, the algorithm-1 is modeled as a region-based strategy using a classification framework, whereas the algorithm-2 is modeled as a boundary-based approach that uses the level set framework. Two sets of databases (DB), Japan DB (JDB) (202 patients, 404 images) and Hong Kong DB (HKDB) (50 patients , 300 images) were used in this study. Two trained neu-roradiologists performed manual LD tracings. The mean automated LD measured was 6.35 ± 0.95 mm for JDB and 6.20 ± 1.35 mm for HKDB. The precision-of-merit was: 97.4 % and 98.0 % w.r.t to two manual tracings for JDB and 99.7 % and 97.9 % w.r.t to two manual tracings for HKDB. Statistical tests such as ANOVA, Chi-Squared, T-test, and Mann-Whitney test were conducted to show the stability and reliability of the automated techniques.

Research paper thumbnail of A Review on Carotid Ultrasound Atherosclerotic Tissue Characterization and Stroke Risk Stratification in Machine Learning Framework

Current Atherosclerotic Reports, 2015

Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause o... more Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause of death in today's world. However, very little is understood about the arterial mechanics of plaque buildup, arterial fibrous cap rupture, and the role of abnormalities of the vasa vasorum. Recently, ultrasonic echogenicity characteristics and morphological characterization of carotid plaque types have been shown to have clinical utility in classification of stroke risks. Furthermore, this characterization supports aggressive and intensive medical therapy as well as procedures, including end-arterectomy and stenting. This is the first state-of-the-art review to provide a comprehensive understanding of the field of ultrasonic vascular morphology tissue characterization. This paper presents fundamental and advanced ultrasonic tissue characterization and feature extraction methods for analyzing plaque. Additionally, the paper shows how the risk stratifica-tion is achieved using machine learning paradigms. More advanced methods need to be developed which can segment the carotid artery walls into multiple regions such as the bulb region and areas both proximal and distal to the bulb. Furthermore, multimodality imaging is needed for validation of such advanced methods for stroke and cardiovascular risk stratification.

Research paper thumbnail of Magnetic Resonance Image Denoising Using Nonlocal Maximum Likelihood Paradigm in DCT-Framework

Wiley, 2015

The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that... more The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that has its origin in the thermal Brownian motion of electrons. Denoising can enhance the quality (by improving the SNR) of the acquired MR image, which is important for both visual analysis and other post processing operations. Recent works on maximum likelihood (ML) based denoising shows that ML methods are very effective in denoising MR images and has an edge over the other state-of-the-art methods for MRI denoising. Among the ML based approaches, the Nonlocal maximum likelihood (NLML) method is commonly used. In the conventional NLML method, the samples for the ML estimation of the unknown true pixel are chosen in a nonlocal fashion based on the intensity similarity of the pixel neighborhoods. Euclidean distance is generally used to measure this similarity. It has been recently shown that computing similarity measure is more robust in discrete cosine transform (DCT) subspace, compared with Euclidean image subspace. Motivated by this observation , we integrated DCT into NLML to produce an improved MRI filtration process. Other than improving the SNR, the time complexity of the conventional NLML can also be significantly reduced through the proposed approach. On synthetic MR brain image, an average improvement of 5% in PSNR and 86%reduction in execution time is achieved with a search window size of 91 3 91 after incorporating the improvements in the existing NLML method. On an experimental kiwi fruit image an improvement of 10% in PSNR is achieved. We did experiments on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method.

Research paper thumbnail of Accurate lumen diameter measurement in curved vessels in carotid ultrasound an iterative scale‑space and spatial transformation approach

Medical Biological Engineering and Computing, 2016

Monitoring of cerebrovascular diseases via carotid ultrasound has started to become a routine. Th... more Monitoring of cerebrovascular diseases via carotid
ultrasound has started to become a routine. The measurement
of image-based lumen diameter (LD) or inter-adventitial
diameter (IAD) is a promising approach for quantification of
the degree of stenosis. The manual measurements of LD/IAD
are not reliable, subjective and slow. The curvature associated
with the vessels along with non-uniformity in the plaque growth
poses further challenges. This study uses a novel and generalized
approach for automated LD and IAD measurement based
on a combination of spatial transformation and scale-space. In
this iterative procedure, the scale-space is first used to get the
lumen axis which is then used with spatial image transformation
paradigm to get a transformed image. The scale-space is
then reapplied to retrieve the lumen region and boundary in the
transformed framework. Then, inverse transformation is applied
to display the results in original image framework. Two hundred
and two patients’ left and right common carotid artery (404
carotid images) B-mode ultrasound images were retrospectively analyzed. The validation of our algorithm has done against
the two manual expert tracings. The coefficient of correlation
between the two manual tracings for LD was 0.98 (p < 0.0001)
and 0.99 (p < 0.0001), respectively. The precision of merit
between the manual expert tracings and the automated system
was 97.7 and 98.7%, respectively. The experimental analysis
demonstrated superior performance of the proposed method
over conventional approaches. Several statistical tests demonstrated
the stability and reliability of the automated system.

Research paper thumbnail of State-of-the-art review on automated lumen and adventitial border delineation and its measurements in carotid ultrasound

Computer Methods and Programs in Biomedicine, 2018

Background and objective: Accurate, reliable, efficient, and precise measurements of the lumen ge... more Background and objective: Accurate, reliable, efficient, and precise measurements of the lumen geom- etry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the plaque burden can be predicted using the automated carotid lumen diameter (LD)/inter- adventitial diameter (IAD) measurements from B-mode ultrasound images. The objective of this review is to present the state-of-the-art methods and systems for the measurement of LD/IAD in CCA based on automated or semi-automated strategies. Further, the performance of these systems is compared based on various metrics for its measurements. Methods: The automated algorithms proposed for the segmentation of carotid lumen are broadly classi- fied into two different categories as: region-based and boundary-based. These techniques are discussed in detail specifying their pros and cons. Further, we discuss the challenges encountered in the segmen- tation process along with its quantitative assessment. Lastly, we present stenosis quantification and risk stratification strategies. Results: Even though, we have found more boundary-based approaches compared to region-based ap- proaches in the literature, however, the region-based strategy yield more satisfactory performance. Novel risk stratification strategies are presented. On a patient database containing 203 patients, 9 patients are identified as high risk patients, whereas 27 patients are identified as medium risk patients. Conclusions: We have presented different techniques for the lumen segmentation of the common carotid artery from B-mode ultrasound images and measurement of lumen diameter and inter-adventitial di- ameter. We believe that the issue regarding boundary-based techniques can be compensated by taking regional statistics embedded with boundary-based information.

Research paper thumbnail of A Semi-automatic Method for Carotid Artery Wall Segmentation in MR Images

IEEE, 2016

The quantification of carotid artery stenosis via imaging techniques guides the physicians to tak... more The quantification of carotid artery stenosis via imaging techniques guides the physicians to take a decision regarding surgical interventions. The measurement of wall thickness from magnetic resonance (MR) images is a promising approach to measure the degree of carotid stenosis. Manual tracing of the carotid vessel walls is time consuming and is sensitive to observer variability. Further, the existing segmen-tation techniques are limited by the poor contrast and presence of noise in MR images. The objective this paper is to present a novel segmentation strategy for carotid lumen and outer wall from MR images. The segmentation has been carried out in two stages which starts with a user assisted region of interest selection. In the first stage, an active contour based global segmentation has been applied to classify the lumen region. In the second stage, morphological gradient of the region of interest has been computed. This is followed by particle swarm optimization based localized segmentation to separate the wall region. The results demonstrate excellent correspondence between the automatic and manual tracings for lumen and outer walls of the carotid artery.

Research paper thumbnail of A Hybrid Method for Object Identification and Event Detection in Video

IEEE, 2013

Video event detection (VED) is a challenging task especially with a large variety of objects in t... more Video event detection (VED) is a challenging task especially with a large variety of objects in the environment. Even though there exist numerous algorithms for event detection, most of them are unsuitable for a typical consumer purpose. A hybrid method for detecting and identifying the moving objects by their color and spatial information is presented in this paper. In tracking multiple moving objects, the system makes use of motion of changed regions. In this approach, first, the object detector will look for the existence of objects that have already been registered. Then the control is passed on to an event detector which will wait for an event to happen which can be object placement or object removal. The object detector becomes active only if any event is detected. Simple training procedure using a single color camera in HSV color space makes it a consumer application. The proposed model has proved to be robust in various indoor environments and different types of background scenes. The experimental results prove the feasibility of the proposed method.