Ömer Faruk Bozkurt - Academia.edu (original) (raw)

Papers by Ömer Faruk Bozkurt

Journal of Reconstructive Urology

Penile curvature is a disease that can be seen in approximately up to 9% of the male population a... more Penile curvature is a disease that can be seen in approximately up to 9% of the male population and can cause various sexual dysfunctions. 1 Although penile curvature often develops secondary to Peyronie's disease, it can also be seen as congenital penile curvature. 2 Although it is known that plaque formation is spontaneously absorbed in most Peyronie's patients and heals without the need for additional treatment, it is reported that approximately 10% of the patients require surgical treatment. 3 Among the surgical treat

Turkish Journal of Biology

This study investigated the immunohistochemical staining characteristics of glutathione-S-transfe... more This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase (GST) alpha, pi, mu, and theta in prostatic acinar adenocarcinoma (PCA), prostatic intraepithelial neoplasia (PIN), and benign prostatic tissues from 19 patients. Relationships between GST isoenzyme expression in benign, PIN, and PCA tissue were examined by the Wilcoxon signed-rank test and clinicopathological data were examined by the Spearman correlation rank test. When the benign, PIN, and PCA tissues from these cases were compared according to their staining intensity, GST alpha, pi, mu, and theta expressions in tumor cells were significantly lower than in benign epithelial cells (P < 0.05). The GST alpha class displayed the lowest level of expression in PIN and PCA. Expression of GST pi was lower in PCA tissue than in PIN and benign epithelial tissue (P < 0.05). We hypothesize that carcinogenesis in the prostate results from impaired cellular handling of mutagenic agents owing to reduction or loss of expression of multiple GST isoenzymes and other detoxifying and antimutagenesis agents. This study confirms the down-regulation of GST isoenzymes in PCA of the prostate and shows that the loss of GST isoenzyme expression is a phenotype associated with malignant transformation. There was no statistical relationship between GST isoenzyme expression and the clinicopathological data (age, Gleason score, and total serum prostate-specific antigen levels) (P > 0.05).

Ege Tıp Dergisi

Aim: To determine the value of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR)... more Aim: To determine the value of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), systemic immune-inflammation (SII) index and De-Ritis ratio, which are among preoperative whole blood and biochemical parameters, in the diagnosis of testicular tumor. Materials and Methods: The data of patients who underwent inguinal orchiectomy for testicular tumor in our clinic between October 2010 and December 2019 and patients who underwent varicocelectomy, as a control group, were retrospectively analyzed. Patients with missing data, under 18 years of age or with additional morbidity were excluded from the present study. Prediction values for NLR, PLR, LMR, SII index and De-Ritis ratio were determined and the value of these parameters in the diagnosis of testicular tumor was examined. Results: Thirty-four (14.1%) patients underwent inguinal orchiectomy while 207 (85.9%) patients underwent varicocelectomy in the present study. The median age of the...

Mathews Journal of Urology and Nephrology, Sep 17, 2018

Anatolian Current Medical Journal, 2022

Objective: To investigate the efficacy of intravaginal laser therapy applied concurrently with me... more Objective: To investigate the efficacy of intravaginal laser therapy applied concurrently with mesh excision for the treatment of vaginal polypropylene mesh exposure or extrusion, which is the most common complication after transobturator tape (TOT), on the recurrence of incontinence. Material and Method: The data of 49 patients who underwent mesh excision due to vaginal mesh exposure or extrusion in our clinic between January 2009 and January 2020 were retrospectively analyzed. The patients were divided into two groups as simultaneous intravaginal laser therapy during the mesh excision (EL, n=23) and only mesh excision (EO, n=26). Data of the patients and long-term stress urinary incontinence (SUI) recurrence rates were determined and the groups were compared. Results: The mean age of the patients was 50.4±9.9 years and the mean follow-up period was 33.3±22.1 months. SUI recurrence in 1-h pad test was significantly lower in the EL group than the EO group at the 12 th month evaluation (8.7% vs 34.6% p=0.030 respectively). According to multivariate regression analysis operation type was an independent risk factor for SUI recurrence (p=0.021). However, there was no significant difference between the groups in terms of postoperative incontinence quality of life questionnaire (I-QOL) scores (p=0.082). Conclusion: Concomitant laser treatment applied with the mesh excision for the treatment of vaginal meshexposure or extrusion secondary to TOT surgery provides a significant advantage in preventing the recurrence of SUI.

Turkish Journal of Trauma and Emergency Surgery, 2021

BACKGROUND: To compare the patients who underwent early surgical repair of penile fracture, which... more BACKGROUND: To compare the patients who underwent early surgical repair of penile fracture, which is one of the urological emergencies, and patients who recovered with conservative treatment concerning long-term sexual functions. METHODS: The data of 42 patients who applied to our clinic with penile fracture between January 2010 and January 2020 were retrospectively analyzed. The patients were categorized into two groups as early operated and followed-up conservatively. The preoperative and postoperative findings of the patients were compared with the International Erectile Function Scale (IIEF-6) scores in the long-term follow-up. RESULTS: The median age of the patients was 35 (20-65) years and the median follow-up period was 52 (8-120) months. The postoperative mean IIEF-6 score of the patients was 22.98±6.52. There was no significant difference between the surgical and the conservative groups concerning postoperative complications (p=0.460). In the follow-up period, the presence of palpable plaque on the rupture area was significantly higher in the conservative group (p=0.041). However, there was no significant difference between the groups concerning IIEF-6 scores (p=0.085). CONCLUSION: Although there is no significant difference in long-term IIEF-6 scores between the two groups, the rate of palpable plaque formation is higher in patients followed-up conservatively. Therefore, early surgical repair should be considered in the foreground, especially in patients with a large rupture area.

Objectives: It was aimed to evaluate the effectiveness of combined use of ultrasonography (US) an... more Objectives: It was aimed to evaluate the effectiveness of combined use of ultrasonography (US) and plain radiography (PR) in the postoperative follow-up of patients undergoing retrograde intrarenal surgery (RIRS). Materials and methods: The charts of 207 patients who underwent RIRS for renal stones in a 3-years-period were retrospectively reviewed. Fifty-eight patients were included to study who were evaluated with combination of urinary US, PR and computed tomography (CT) at 1 month after surgery. Results: Of 58 procedures with perioperative complete stone fragmentation, 49 were completely stone-free (84.4%), while fragments (≥ 3 mm) were observed in 9 patients and hydronephrosis was detected in 5 patients (8.6%) on the CT. Of the 9 residual stones and 5 hydronephrosis, the radiologists truly diagnosed 6 stones (66.6%) and 5 hydronephrosis (100%) by using the combination of US and PR. The sensitivity, specificity, positive and nega tive predictive values of US and PR for detecting presence of residual stone and hydronephrosis were 66.6% and 100%, 98% and 98%, 85.7% and 83.3%, 94.2% and 100%, respectively. Conclusions: A combination of urinary US and plain film has clear advantages about lack of radiation exposure over CT scan and it is a highly specific and sensitive test for detecting hydronephrosis. However this procedure has limited accuracy for detecting small residual stones, so we believe that CT scan is only necessary when patient has persistent pain or sonographic evidence of hydronephrosis is present.

Kocaeli Tıp Dergisi, Apr 1, 2021

Journal of Health Sciences and Medicine, 2022

Objective: We aimed to indicate the effectiveness of local anesthesia in the treatment of hydrodi... more Objective: We aimed to indicate the effectiveness of local anesthesia in the treatment of hydrodistention in women with Bladder Pain Syndrome/interstitial Cystitis (BPS/IC) in our study. Material and Method: The data of a total of 77 female patients who underwent hydrodistention treatment for BPS/IC in our clinic between January 2015 and July 2021 were analyzed retrospectively. The patients were divided into two groups as local anesthesia (LA, n=41) and spinal anesthesia (SA, n=36) groups according to the type of anesthesia applied. The groups were compared by determining the preoperative and postoperative O'Leary symptom index (SI) and problem index (PI), minimum voiding volume (MinVV), maximum voiding volume (MaxVV), average voiding volume (AvgVV) and daily frequency. Results: The mean age of the patients was 48.97±11.09 years in the LA group and 45.19±14.35 years in the SA group (p=0.197). There was no significant difference between the groups in terms of the preoperative European Society for the Study of Interstitial Cystitis (ESSIC) group (p=0.999). During the postoperative period, a median (IQR) improvement of 11.0 (2.0) points was observed in the SI of the LA group, while a median improvement of 11.0 (2.0) points were observed in the SA group (p=0.437). The median improvement in PI score was 8.4 (4.0) points in the SA group, while it was 7.0 (3.0) points in the LA group (p=0.415). There was no significant difference between the groups in terms of improvements in minVV, maxVV, avgVV and daily frequency (p=0.480, p=0.460, p=0.614 and p=0.910, respectively). Conclusion: Hydrodistention treatment in women with BPS/IC can be performed safely and with high success rate under local anesthesia and it is well tolerated by the patients. Local anesthesia offers a minimally invasive treatment option as well as the advantage of avoiding possible complications of spinal, epidural or general anesthesia.

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2009

Bladder calculi account for 5% of all urinary system calculi. They are usually seen in older men ... more Bladder calculi account for 5% of all urinary system calculi. They are usually seen in older men and occur because of infravesical obstructions such as prostate hyperplasia , neurogenic voiding dysfunction. Infection, foreign bodies, anti incontinence surgery in woman and rarely pregnancy can also be predisposing factors for bladder calculus. But they can be rarely seen in children and young, healthy patiants without any predisposing factors and are called endemic bladder calculi. İn this case report we present a 23 years old man who has endemic giant bladder calculus and on whom we performed cystolithotomy . The stone weighed 102 gr and measured 53x52x43 mm in size. And it was composed of calcium and oxalate. There were no predisposing factors in this giant bladder calculus. The aim of this case report was to emphasize the fact that bladder calculi can develop in young healthy men without any predisposing factors and that it can be diagnosed readily with DUSG and/or urinary tract USG.

Turkish Journal of Obstetrics and Gynecology, 2010

PURPOSE: This study was conducted to assess the clinical efficacy of a single dose of fosfomycin ... more PURPOSE: This study was conducted to assess the clinical efficacy of a single dose of fosfomycin trometamol for the treatment of both asymptomatic and symptomatic bacteriuria in the third trimester of pregnancy compared with a 7-day regimen of amoxicillin-clavulanic acid MATERIAL – METHODS: In this study clinical efficiency of single dose of 3 g fosfomycin trometamol and 7 day 675 mg amoxicillin-clavulanic acid were compared on 85 pregnant women in 3rd trimester with symptomatic and asymptomatic bacteriauria. Patients divided into four groups and single dose of fosfomycin trometamol applied on group 1 (asymptomatic bacteriauria patients) and group 3 (symptomatic bacteriauria patients) while 7 day 675 mg amoxicillin-clavulanic acid applied on group 2 (asymptomatic bacteriauria patients) and group 4 (symptomatic bacteriauria patients). Microbiological assessments ( urine analyses and culture ) and rutine biochemical tests were performed before and at 7 days after the administration. N...

Journal of Reconstructive Urology, 2021

Anatolian Current Medical Journal, 2021

Objective: To compare the efficacy of combined semi-rigid+ flexible ureterorenoscopic surgery (UR... more Objective: To compare the efficacy of combined semi-rigid+ flexible ureterorenoscopic surgery (URS+RIRC) and percutaneous nephrolithotomy (PNL), which is the standard method for the surgery of ≥2 cm upper ureteral impacted stones. Material and Method: The data of 123 patients who underwent stone surgery for ≥2 cm impacted ureteral stones in the upper ureter in our clinic were retrospectively analyzed. The patients were divided into two groups as URS+RIRC (n=59) and PNL (n=64) according to the type of operation. Patients with stones impacted in the ureter at the level between the L4 vertebra and ureteropelvic junction were included in the study. Preoperative demographic data and postoperative results of the patients in two groups were compared. Results: Average operation time was similar in both groups (p=0.147). Mean hospital stay was significantly higher in the PNL group compared to the URS+RIRC group (3.28±0.57 days vs 1.11±0.32 days, p=0.001). Mucosal injury was developed in 10 (16.9%) patients in the URS+RIRC group during the operation, while it was only 3 (4.7%) in the PNL group (p=0.027). Postoperative urinary tract infection development was found to be similar in URS+RIRC and PNL groups (8.5% vs 4.7%, p=0.479).Postoperativestone-free rate was found to be significantly higher in the PNL group compared to the URS+RIRC group (95.3% vs 79.7%, p=0.008). Conclusion: PNL is a very effective and safe procedure in the surgical treatment of stones ≥2 cm in diameter impacted in the upper ureter. The complication rate of PNL is comparable with URS+RIRC; however, it is seen that the PNL is more advantageous than URS+RIRC in terms of postoperative total stone-free rate.

Androloji Bülteni, 2021

OBJECTIVE: Evaluation of the sexual functions in adults who have undergone surgery for distal hyp... more OBJECTIVE: Evaluation of the sexual functions in adults who have undergone surgery for distal hypospadias in childhood, according to the type of operation performed. MATERIAL and METHODS: A total of 48 adult male participants who underwent a single-session distal hypoapadias operation during childhood were included in the study. Participants were divided into four groups according to the type of operation performed: meatal advancement and glanuloplasty (MAGPI), urethral advancement and glanuloplasty (URAGPI), glanular approximation plasty (GAP) and tubularized incised plate urethroplasty (TIPU). Participants' international index of erectile function-5 score (IIEF-5), premature ejaculation diagnostic tool (PEDT), orgasmic function score (OF), sexual desire score (SD), intercourse satisfaction score (IS) and overall satisfaction score (OS) were determined and groups were compared. RESULTS: It was determined that 12 (25.0%) of the participants had MAGPI, 9 (18.8%) URAGPI, 9 (18.8%) GAP and 18 (37.5%) TIPU procedure. The median IIEF-5 score of the participants was 22.5 (21.25-24) in the MAGPI group, 21 (16-23.5) in the URAGPI group, 23 (21.5-24.5) in the GAP group, and 22.5 (20.75-24) in the TIPU group (p=0.201). The median PEDT score of the participants was 5.5 (4-7.75) in the MAGPI group, 6 (4.5-11.5) in the URAGPI group, 6 (2.5-7.5) in the GAP group, and 5.5 (3.75-7) in the TIPU group (p=0.813). There was no significant difference between the groups in terms of median OF, SD, IS and OS scores (p=0.899, p=0.316, p=0.107 and P=0.504, respectively). CONCLUSION: It was determined that the erectile function and premature ejaculation parameters of adults who had undergone singlesession distal hypospadias surgery during childhood were not affected by the type of operation performed.

Objective: To report our experience in percutaneous nephrolithotomy and endoscopic urinary tract ... more Objective: To report our experience in percutaneous nephrolithotomy and endoscopic urinary tract stone surgery in patients with urinary diversion and vesicostomy. Materials and Methods: Data of 21 patients with urinary diversion or vesicostomy who underwent surgery for urinary tract stones in our clinic between January 2008 and January 2020 were retrospectively analyzed. Eight patients (38%) underwent percutaneous nephrolithotomy, 2 patients (9.5%) underwent antegrade flexible ureteroscopy, 4 patients (19.0%) underwent retrograde semi-rigid or flexible ureteroscopy, 5 patients (23.8%) underwent retrograde pouch lithotripsy and 2 patients (9.5%) underwent percutaneous cystolithotripsy with vesicostomy tract entrance.Preoperative and postoperative data of the patients were evaluated. Results: The male to female ratio was 16/5. The mean age of the patients was 54.6 ± 10.1 years and mean preoperative stone diameter was 2.8 ± 4.5 cm. It was determined that 14 patients (66.6%) had ileal c...

Journal of Reconstructive Urology, 2021

Yeni Üroloji Dergisi, 2019

Amac: Biz bu tek merkezli calismada, daha once ayni taraf sok dalga litotripsi (SWL), perkutan ne... more Amac: Biz bu tek merkezli calismada, daha once ayni taraf sok dalga litotripsi (SWL), perkutan nefrolitotomi (PNL) veya acik bobrek tas cerrahisi olan ve olmayan cocuk hastalarda uyguladigimiz PNL ope- rasyonlarinin perioperatif sonuclarini karsilastirmayi amacladik. Gerec ve Yontemler: 2008–2016 tarihleri arasinda klinigimizde PNL operasyonu uygulanmis 18 yas alti cocuklarin verileri retrospektif olarak degerlendirildi. Olgular, bobrek tasi tanisi ile daha once ayni taraf SWL, PNL veya acik cerrahiyi iceren tas tedavisi oykusu olanlar (grup 1) ve olmayanlar (grup 2) olarak iki gruba ayrildi. Demografik veriler ile preoperatif ve operatif veriler belirlenen gruplar arasinda karsilastirildi. Postoperatif 6. haftada cekilen direkt uriner sistem grafisinde (radyolusent taslarda kontrastsiz bilgisayarli tomografide) 4 mm ve uzeri taslar reziduel tas olarak kabul edildi. Postoperatif komplikasyonlar modifiye Clavien siniflamasina gore kaydedildi. PNL sonrasi reziduel tas varligi ve kompl...

49 yasinda erkek hasta dis merkezde, mevcut akciger malign epitelyal tumore yonelik yapilan tetki... more 49 yasinda erkek hasta dis merkezde, mevcut akciger malign epitelyal tumore yonelik yapilan tetkiklerinde, sag bobrekte cross-fused ektopi ve sag renal kitle saptanmasi uzerine tarafimiza yonlendirildi. Ultrasonografisinde(USG); sag bobrekte cross-fused ektopi ve alt lobdan kaynaklanan 55*40*83 mm boyutlu heterojen kitle lezyon saptandi. Manyetik rezonans goruntuleme(MRI)’de; sag bobrek cross ektopik batin sol kisminda izlendi ayrica ektopik bobrek alt polunden, batin sol alt yarisina ve pelvik bolgeye uzanan 94*61 mm T1A sekanslarda hipointens, T2A sekanslarda heterojen kontrastlanan kitle lezyon izlendi. Hastaya radikal nefrektomi operasyonu uygulandi. Postoperatif 1. ayda batin sol kisminda hassasiyet ve sislik nedeniyle tarafimiza basvuran hastanin Bilgisayarli tomografide(BT); yaklasik 10 cm capli urinom saptanmasi uzerine hastanin urinom alanina perkutan dren yerlestirildi. Takiplerinde drenden gelen sivinin azaldigi ve 20 gun sonrasinda kesildiginin izlenmesi uzerine dreni al...

Ural Oguz1, Gülçin Şimşek2, Erhan Demirelli1, Çağrı Şenocak3, Berkan Reşorlu4, Ömer Faruk Bozkurt... more Ural Oguz1, Gülçin Şimşek2, Erhan Demirelli1, Çağrı Şenocak3, Berkan Reşorlu4, Ömer Faruk Bozkurt3, Ali Ünsal5 1Giresun Üniversitesi Tıp Fakültesi, Üroloji Anabilim Dalı, Giresun, Türkiye 2Keçiören Eğitim Araştırma Hastanesi, Patoloji Kliniği, Ankara, Türkiye 3Keçiören Eğitim Araştırma Hastanesi, Üroloji Kliniği, Ankara, Türkiye 4Memorial Ankara Hastanesi, Üroloji Kliniği, Ankara, Türkiye 5Gazi Üniversitesi Tıp Fakültesi, Üroloji Anabilim Dalı, Ankara, Türkiye,

Turkish Journal of Pediatric Disease, 2018

Objective: We aimed to present the outcomes and complications of percutaneous nephrolithotomy (PC... more Objective: We aimed to present the outcomes and complications of percutaneous nephrolithotomy (PCNL) performed during childhood in a comparative manner among different age groups. Material and Methods: We retrospectively evaluated children under 18 years of age who underwent the PCNL operation between 2008 and 2016 at our clinic. Cases were further divided into three age categories as >6, 6–11, and 12–17 years. Demographic data, and the preoperative and operative data were compared between the selected age groups. We used kidney-ureter-bladder radiography (non-contrast-enhanced computed tomography in cases with non-opaque stones) that was performed 6 weeks postoperatively for the assessment of residual stones (≥4 mm). Postoperative complications were recorded according to the modified Clavien classification. Residual stone rates and complications of PCNL were compared between the three age groups. Pediatrik Perkütan Nefrolitotomi Operasyonu Sonuçlarının Değişik Yaş Grupları Arası...

Journal of Reconstructive Urology

Penile curvature is a disease that can be seen in approximately up to 9% of the male population a... more Penile curvature is a disease that can be seen in approximately up to 9% of the male population and can cause various sexual dysfunctions. 1 Although penile curvature often develops secondary to Peyronie's disease, it can also be seen as congenital penile curvature. 2 Although it is known that plaque formation is spontaneously absorbed in most Peyronie's patients and heals without the need for additional treatment, it is reported that approximately 10% of the patients require surgical treatment. 3 Among the surgical treat

Turkish Journal of Biology

This study investigated the immunohistochemical staining characteristics of glutathione-S-transfe... more This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase (GST) alpha, pi, mu, and theta in prostatic acinar adenocarcinoma (PCA), prostatic intraepithelial neoplasia (PIN), and benign prostatic tissues from 19 patients. Relationships between GST isoenzyme expression in benign, PIN, and PCA tissue were examined by the Wilcoxon signed-rank test and clinicopathological data were examined by the Spearman correlation rank test. When the benign, PIN, and PCA tissues from these cases were compared according to their staining intensity, GST alpha, pi, mu, and theta expressions in tumor cells were significantly lower than in benign epithelial cells (P < 0.05). The GST alpha class displayed the lowest level of expression in PIN and PCA. Expression of GST pi was lower in PCA tissue than in PIN and benign epithelial tissue (P < 0.05). We hypothesize that carcinogenesis in the prostate results from impaired cellular handling of mutagenic agents owing to reduction or loss of expression of multiple GST isoenzymes and other detoxifying and antimutagenesis agents. This study confirms the down-regulation of GST isoenzymes in PCA of the prostate and shows that the loss of GST isoenzyme expression is a phenotype associated with malignant transformation. There was no statistical relationship between GST isoenzyme expression and the clinicopathological data (age, Gleason score, and total serum prostate-specific antigen levels) (P > 0.05).

Ege Tıp Dergisi

Aim: To determine the value of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR)... more Aim: To determine the value of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), systemic immune-inflammation (SII) index and De-Ritis ratio, which are among preoperative whole blood and biochemical parameters, in the diagnosis of testicular tumor. Materials and Methods: The data of patients who underwent inguinal orchiectomy for testicular tumor in our clinic between October 2010 and December 2019 and patients who underwent varicocelectomy, as a control group, were retrospectively analyzed. Patients with missing data, under 18 years of age or with additional morbidity were excluded from the present study. Prediction values for NLR, PLR, LMR, SII index and De-Ritis ratio were determined and the value of these parameters in the diagnosis of testicular tumor was examined. Results: Thirty-four (14.1%) patients underwent inguinal orchiectomy while 207 (85.9%) patients underwent varicocelectomy in the present study. The median age of the...

Mathews Journal of Urology and Nephrology, Sep 17, 2018

Anatolian Current Medical Journal, 2022

Objective: To investigate the efficacy of intravaginal laser therapy applied concurrently with me... more Objective: To investigate the efficacy of intravaginal laser therapy applied concurrently with mesh excision for the treatment of vaginal polypropylene mesh exposure or extrusion, which is the most common complication after transobturator tape (TOT), on the recurrence of incontinence. Material and Method: The data of 49 patients who underwent mesh excision due to vaginal mesh exposure or extrusion in our clinic between January 2009 and January 2020 were retrospectively analyzed. The patients were divided into two groups as simultaneous intravaginal laser therapy during the mesh excision (EL, n=23) and only mesh excision (EO, n=26). Data of the patients and long-term stress urinary incontinence (SUI) recurrence rates were determined and the groups were compared. Results: The mean age of the patients was 50.4±9.9 years and the mean follow-up period was 33.3±22.1 months. SUI recurrence in 1-h pad test was significantly lower in the EL group than the EO group at the 12 th month evaluation (8.7% vs 34.6% p=0.030 respectively). According to multivariate regression analysis operation type was an independent risk factor for SUI recurrence (p=0.021). However, there was no significant difference between the groups in terms of postoperative incontinence quality of life questionnaire (I-QOL) scores (p=0.082). Conclusion: Concomitant laser treatment applied with the mesh excision for the treatment of vaginal meshexposure or extrusion secondary to TOT surgery provides a significant advantage in preventing the recurrence of SUI.

Turkish Journal of Trauma and Emergency Surgery, 2021

BACKGROUND: To compare the patients who underwent early surgical repair of penile fracture, which... more BACKGROUND: To compare the patients who underwent early surgical repair of penile fracture, which is one of the urological emergencies, and patients who recovered with conservative treatment concerning long-term sexual functions. METHODS: The data of 42 patients who applied to our clinic with penile fracture between January 2010 and January 2020 were retrospectively analyzed. The patients were categorized into two groups as early operated and followed-up conservatively. The preoperative and postoperative findings of the patients were compared with the International Erectile Function Scale (IIEF-6) scores in the long-term follow-up. RESULTS: The median age of the patients was 35 (20-65) years and the median follow-up period was 52 (8-120) months. The postoperative mean IIEF-6 score of the patients was 22.98±6.52. There was no significant difference between the surgical and the conservative groups concerning postoperative complications (p=0.460). In the follow-up period, the presence of palpable plaque on the rupture area was significantly higher in the conservative group (p=0.041). However, there was no significant difference between the groups concerning IIEF-6 scores (p=0.085). CONCLUSION: Although there is no significant difference in long-term IIEF-6 scores between the two groups, the rate of palpable plaque formation is higher in patients followed-up conservatively. Therefore, early surgical repair should be considered in the foreground, especially in patients with a large rupture area.

Objectives: It was aimed to evaluate the effectiveness of combined use of ultrasonography (US) an... more Objectives: It was aimed to evaluate the effectiveness of combined use of ultrasonography (US) and plain radiography (PR) in the postoperative follow-up of patients undergoing retrograde intrarenal surgery (RIRS). Materials and methods: The charts of 207 patients who underwent RIRS for renal stones in a 3-years-period were retrospectively reviewed. Fifty-eight patients were included to study who were evaluated with combination of urinary US, PR and computed tomography (CT) at 1 month after surgery. Results: Of 58 procedures with perioperative complete stone fragmentation, 49 were completely stone-free (84.4%), while fragments (≥ 3 mm) were observed in 9 patients and hydronephrosis was detected in 5 patients (8.6%) on the CT. Of the 9 residual stones and 5 hydronephrosis, the radiologists truly diagnosed 6 stones (66.6%) and 5 hydronephrosis (100%) by using the combination of US and PR. The sensitivity, specificity, positive and nega tive predictive values of US and PR for detecting presence of residual stone and hydronephrosis were 66.6% and 100%, 98% and 98%, 85.7% and 83.3%, 94.2% and 100%, respectively. Conclusions: A combination of urinary US and plain film has clear advantages about lack of radiation exposure over CT scan and it is a highly specific and sensitive test for detecting hydronephrosis. However this procedure has limited accuracy for detecting small residual stones, so we believe that CT scan is only necessary when patient has persistent pain or sonographic evidence of hydronephrosis is present.

Kocaeli Tıp Dergisi, Apr 1, 2021

Journal of Health Sciences and Medicine, 2022

Objective: We aimed to indicate the effectiveness of local anesthesia in the treatment of hydrodi... more Objective: We aimed to indicate the effectiveness of local anesthesia in the treatment of hydrodistention in women with Bladder Pain Syndrome/interstitial Cystitis (BPS/IC) in our study. Material and Method: The data of a total of 77 female patients who underwent hydrodistention treatment for BPS/IC in our clinic between January 2015 and July 2021 were analyzed retrospectively. The patients were divided into two groups as local anesthesia (LA, n=41) and spinal anesthesia (SA, n=36) groups according to the type of anesthesia applied. The groups were compared by determining the preoperative and postoperative O'Leary symptom index (SI) and problem index (PI), minimum voiding volume (MinVV), maximum voiding volume (MaxVV), average voiding volume (AvgVV) and daily frequency. Results: The mean age of the patients was 48.97±11.09 years in the LA group and 45.19±14.35 years in the SA group (p=0.197). There was no significant difference between the groups in terms of the preoperative European Society for the Study of Interstitial Cystitis (ESSIC) group (p=0.999). During the postoperative period, a median (IQR) improvement of 11.0 (2.0) points was observed in the SI of the LA group, while a median improvement of 11.0 (2.0) points were observed in the SA group (p=0.437). The median improvement in PI score was 8.4 (4.0) points in the SA group, while it was 7.0 (3.0) points in the LA group (p=0.415). There was no significant difference between the groups in terms of improvements in minVV, maxVV, avgVV and daily frequency (p=0.480, p=0.460, p=0.614 and p=0.910, respectively). Conclusion: Hydrodistention treatment in women with BPS/IC can be performed safely and with high success rate under local anesthesia and it is well tolerated by the patients. Local anesthesia offers a minimally invasive treatment option as well as the advantage of avoiding possible complications of spinal, epidural or general anesthesia.

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2009

Bladder calculi account for 5% of all urinary system calculi. They are usually seen in older men ... more Bladder calculi account for 5% of all urinary system calculi. They are usually seen in older men and occur because of infravesical obstructions such as prostate hyperplasia , neurogenic voiding dysfunction. Infection, foreign bodies, anti incontinence surgery in woman and rarely pregnancy can also be predisposing factors for bladder calculus. But they can be rarely seen in children and young, healthy patiants without any predisposing factors and are called endemic bladder calculi. İn this case report we present a 23 years old man who has endemic giant bladder calculus and on whom we performed cystolithotomy . The stone weighed 102 gr and measured 53x52x43 mm in size. And it was composed of calcium and oxalate. There were no predisposing factors in this giant bladder calculus. The aim of this case report was to emphasize the fact that bladder calculi can develop in young healthy men without any predisposing factors and that it can be diagnosed readily with DUSG and/or urinary tract USG.

Turkish Journal of Obstetrics and Gynecology, 2010

PURPOSE: This study was conducted to assess the clinical efficacy of a single dose of fosfomycin ... more PURPOSE: This study was conducted to assess the clinical efficacy of a single dose of fosfomycin trometamol for the treatment of both asymptomatic and symptomatic bacteriuria in the third trimester of pregnancy compared with a 7-day regimen of amoxicillin-clavulanic acid MATERIAL – METHODS: In this study clinical efficiency of single dose of 3 g fosfomycin trometamol and 7 day 675 mg amoxicillin-clavulanic acid were compared on 85 pregnant women in 3rd trimester with symptomatic and asymptomatic bacteriauria. Patients divided into four groups and single dose of fosfomycin trometamol applied on group 1 (asymptomatic bacteriauria patients) and group 3 (symptomatic bacteriauria patients) while 7 day 675 mg amoxicillin-clavulanic acid applied on group 2 (asymptomatic bacteriauria patients) and group 4 (symptomatic bacteriauria patients). Microbiological assessments ( urine analyses and culture ) and rutine biochemical tests were performed before and at 7 days after the administration. N...

Journal of Reconstructive Urology, 2021

Anatolian Current Medical Journal, 2021

Objective: To compare the efficacy of combined semi-rigid+ flexible ureterorenoscopic surgery (UR... more Objective: To compare the efficacy of combined semi-rigid+ flexible ureterorenoscopic surgery (URS+RIRC) and percutaneous nephrolithotomy (PNL), which is the standard method for the surgery of ≥2 cm upper ureteral impacted stones. Material and Method: The data of 123 patients who underwent stone surgery for ≥2 cm impacted ureteral stones in the upper ureter in our clinic were retrospectively analyzed. The patients were divided into two groups as URS+RIRC (n=59) and PNL (n=64) according to the type of operation. Patients with stones impacted in the ureter at the level between the L4 vertebra and ureteropelvic junction were included in the study. Preoperative demographic data and postoperative results of the patients in two groups were compared. Results: Average operation time was similar in both groups (p=0.147). Mean hospital stay was significantly higher in the PNL group compared to the URS+RIRC group (3.28±0.57 days vs 1.11±0.32 days, p=0.001). Mucosal injury was developed in 10 (16.9%) patients in the URS+RIRC group during the operation, while it was only 3 (4.7%) in the PNL group (p=0.027). Postoperative urinary tract infection development was found to be similar in URS+RIRC and PNL groups (8.5% vs 4.7%, p=0.479).Postoperativestone-free rate was found to be significantly higher in the PNL group compared to the URS+RIRC group (95.3% vs 79.7%, p=0.008). Conclusion: PNL is a very effective and safe procedure in the surgical treatment of stones ≥2 cm in diameter impacted in the upper ureter. The complication rate of PNL is comparable with URS+RIRC; however, it is seen that the PNL is more advantageous than URS+RIRC in terms of postoperative total stone-free rate.

Androloji Bülteni, 2021

OBJECTIVE: Evaluation of the sexual functions in adults who have undergone surgery for distal hyp... more OBJECTIVE: Evaluation of the sexual functions in adults who have undergone surgery for distal hypospadias in childhood, according to the type of operation performed. MATERIAL and METHODS: A total of 48 adult male participants who underwent a single-session distal hypoapadias operation during childhood were included in the study. Participants were divided into four groups according to the type of operation performed: meatal advancement and glanuloplasty (MAGPI), urethral advancement and glanuloplasty (URAGPI), glanular approximation plasty (GAP) and tubularized incised plate urethroplasty (TIPU). Participants' international index of erectile function-5 score (IIEF-5), premature ejaculation diagnostic tool (PEDT), orgasmic function score (OF), sexual desire score (SD), intercourse satisfaction score (IS) and overall satisfaction score (OS) were determined and groups were compared. RESULTS: It was determined that 12 (25.0%) of the participants had MAGPI, 9 (18.8%) URAGPI, 9 (18.8%) GAP and 18 (37.5%) TIPU procedure. The median IIEF-5 score of the participants was 22.5 (21.25-24) in the MAGPI group, 21 (16-23.5) in the URAGPI group, 23 (21.5-24.5) in the GAP group, and 22.5 (20.75-24) in the TIPU group (p=0.201). The median PEDT score of the participants was 5.5 (4-7.75) in the MAGPI group, 6 (4.5-11.5) in the URAGPI group, 6 (2.5-7.5) in the GAP group, and 5.5 (3.75-7) in the TIPU group (p=0.813). There was no significant difference between the groups in terms of median OF, SD, IS and OS scores (p=0.899, p=0.316, p=0.107 and P=0.504, respectively). CONCLUSION: It was determined that the erectile function and premature ejaculation parameters of adults who had undergone singlesession distal hypospadias surgery during childhood were not affected by the type of operation performed.

Objective: To report our experience in percutaneous nephrolithotomy and endoscopic urinary tract ... more Objective: To report our experience in percutaneous nephrolithotomy and endoscopic urinary tract stone surgery in patients with urinary diversion and vesicostomy. Materials and Methods: Data of 21 patients with urinary diversion or vesicostomy who underwent surgery for urinary tract stones in our clinic between January 2008 and January 2020 were retrospectively analyzed. Eight patients (38%) underwent percutaneous nephrolithotomy, 2 patients (9.5%) underwent antegrade flexible ureteroscopy, 4 patients (19.0%) underwent retrograde semi-rigid or flexible ureteroscopy, 5 patients (23.8%) underwent retrograde pouch lithotripsy and 2 patients (9.5%) underwent percutaneous cystolithotripsy with vesicostomy tract entrance.Preoperative and postoperative data of the patients were evaluated. Results: The male to female ratio was 16/5. The mean age of the patients was 54.6 ± 10.1 years and mean preoperative stone diameter was 2.8 ± 4.5 cm. It was determined that 14 patients (66.6%) had ileal c...

Journal of Reconstructive Urology, 2021

Yeni Üroloji Dergisi, 2019

Amac: Biz bu tek merkezli calismada, daha once ayni taraf sok dalga litotripsi (SWL), perkutan ne... more Amac: Biz bu tek merkezli calismada, daha once ayni taraf sok dalga litotripsi (SWL), perkutan nefrolitotomi (PNL) veya acik bobrek tas cerrahisi olan ve olmayan cocuk hastalarda uyguladigimiz PNL ope- rasyonlarinin perioperatif sonuclarini karsilastirmayi amacladik. Gerec ve Yontemler: 2008–2016 tarihleri arasinda klinigimizde PNL operasyonu uygulanmis 18 yas alti cocuklarin verileri retrospektif olarak degerlendirildi. Olgular, bobrek tasi tanisi ile daha once ayni taraf SWL, PNL veya acik cerrahiyi iceren tas tedavisi oykusu olanlar (grup 1) ve olmayanlar (grup 2) olarak iki gruba ayrildi. Demografik veriler ile preoperatif ve operatif veriler belirlenen gruplar arasinda karsilastirildi. Postoperatif 6. haftada cekilen direkt uriner sistem grafisinde (radyolusent taslarda kontrastsiz bilgisayarli tomografide) 4 mm ve uzeri taslar reziduel tas olarak kabul edildi. Postoperatif komplikasyonlar modifiye Clavien siniflamasina gore kaydedildi. PNL sonrasi reziduel tas varligi ve kompl...

49 yasinda erkek hasta dis merkezde, mevcut akciger malign epitelyal tumore yonelik yapilan tetki... more 49 yasinda erkek hasta dis merkezde, mevcut akciger malign epitelyal tumore yonelik yapilan tetkiklerinde, sag bobrekte cross-fused ektopi ve sag renal kitle saptanmasi uzerine tarafimiza yonlendirildi. Ultrasonografisinde(USG); sag bobrekte cross-fused ektopi ve alt lobdan kaynaklanan 55*40*83 mm boyutlu heterojen kitle lezyon saptandi. Manyetik rezonans goruntuleme(MRI)’de; sag bobrek cross ektopik batin sol kisminda izlendi ayrica ektopik bobrek alt polunden, batin sol alt yarisina ve pelvik bolgeye uzanan 94*61 mm T1A sekanslarda hipointens, T2A sekanslarda heterojen kontrastlanan kitle lezyon izlendi. Hastaya radikal nefrektomi operasyonu uygulandi. Postoperatif 1. ayda batin sol kisminda hassasiyet ve sislik nedeniyle tarafimiza basvuran hastanin Bilgisayarli tomografide(BT); yaklasik 10 cm capli urinom saptanmasi uzerine hastanin urinom alanina perkutan dren yerlestirildi. Takiplerinde drenden gelen sivinin azaldigi ve 20 gun sonrasinda kesildiginin izlenmesi uzerine dreni al...

Ural Oguz1, Gülçin Şimşek2, Erhan Demirelli1, Çağrı Şenocak3, Berkan Reşorlu4, Ömer Faruk Bozkurt... more Ural Oguz1, Gülçin Şimşek2, Erhan Demirelli1, Çağrı Şenocak3, Berkan Reşorlu4, Ömer Faruk Bozkurt3, Ali Ünsal5 1Giresun Üniversitesi Tıp Fakültesi, Üroloji Anabilim Dalı, Giresun, Türkiye 2Keçiören Eğitim Araştırma Hastanesi, Patoloji Kliniği, Ankara, Türkiye 3Keçiören Eğitim Araştırma Hastanesi, Üroloji Kliniği, Ankara, Türkiye 4Memorial Ankara Hastanesi, Üroloji Kliniği, Ankara, Türkiye 5Gazi Üniversitesi Tıp Fakültesi, Üroloji Anabilim Dalı, Ankara, Türkiye,

Turkish Journal of Pediatric Disease, 2018

Objective: We aimed to present the outcomes and complications of percutaneous nephrolithotomy (PC... more Objective: We aimed to present the outcomes and complications of percutaneous nephrolithotomy (PCNL) performed during childhood in a comparative manner among different age groups. Material and Methods: We retrospectively evaluated children under 18 years of age who underwent the PCNL operation between 2008 and 2016 at our clinic. Cases were further divided into three age categories as >6, 6–11, and 12–17 years. Demographic data, and the preoperative and operative data were compared between the selected age groups. We used kidney-ureter-bladder radiography (non-contrast-enhanced computed tomography in cases with non-opaque stones) that was performed 6 weeks postoperatively for the assessment of residual stones (≥4 mm). Postoperative complications were recorded according to the modified Clavien classification. Residual stone rates and complications of PCNL were compared between the three age groups. Pediatrik Perkütan Nefrolitotomi Operasyonu Sonuçlarının Değişik Yaş Grupları Arası...