Наталія Рак - Academia.edu (original) (raw)
Наталія Рак
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ХНТУСГ / Kharkiv Petro Vasylenko National Technical University of Agriculture (KhNTUA)
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Scientific research of the XXI century. Volume 2, 2021
Every day, the modern pharmaceutical industry enters new drugs and dosage forms into the world re... more Every day, the modern pharmaceutical industry enters new drugs and dosage forms into the world register. Among the many new drugs, a small number of basic molecules can be noted. Modification of such molecules leads to a change and increase in biological action as well as to a change in toxicity. One such molecule is 1,2,4-triazole. The heterocycle attracts attention due to its excellent biological action on low toxicity. First of all, derivatives of this heterocycle are considered to be powerful antifungal and antimicrobial agents. However, other types of biological action are becoming more common. For example, in medical practice found drugs "Letrozole" and "Anastrazole" as effective antitumor drugs. To achieve this purpose, ZSMU scientists 1 select a matrix based on the nucleus of 1,2,4-triazole at first.
Scientific research of the XXI century. Volume 2, 2021
Every day, the modern pharmaceutical industry enters new drugs and dosage forms into the world re... more Every day, the modern pharmaceutical industry enters new drugs and dosage forms into the world register. Among the many new drugs, a small number of basic molecules can be noted. Modification of such molecules leads to a change and increase in biological action as well as to a change in toxicity. One such molecule is 1,2,4-triazole. The heterocycle attracts attention due to its excellent biological action on low toxicity. First of all, derivatives of this heterocycle are considered to be powerful antifungal and antimicrobial agents. However, other types of biological action are becoming more common. For example, in medical practice found drugs "Letrozole" and "Anastrazole" as effective antitumor drugs. To achieve this purpose, ZSMU scientists 1 select a matrix based on the nucleus of 1,2,4-triazole at first.