CLIFFORD ADAMS - Academia.edu (original) (raw)
Papers by CLIFFORD ADAMS
EPC 2006 - 12th European Poultry Conference, Verona, Italy, 10-14 September, 2006., 2006
A model system was established to evaluate the ability of a pancreatic lipase enzyme to hydrolyse... more A model system was established to evaluate the ability of a pancreatic lipase enzyme to hydrolyse fats and oils, simulating lipid digestion in vitro. Lipid hydrolysis was monitored by quantification of the level of free fatty acids, mono-, di-and triglycerides. In the model system the pancreatic lipase was able to hydrolyse a non-oxidized fat quite rapidly. The activity of the lipase enzyme was severely inhibited by an oxidized oil, indicating that the oxidative status of the fat strongly influences lipid digestibility. In a second stage of the research the relationship between lipid quality and the digestibility was studied in more detail. Stabilization of the fat with antioxidants slowed down the oxidation process and maintained a high lipase activity. These tests directly confirm the beneficial effect of antioxidants to maintain the nutritional profile of the fat. This in vitro model system is a valuable tool to evaluate the digestibility of oils and fats as it may contribute additional information on the nutritional value of lipids used in the poultry industry.
Nutricines and Nutrients, Health Maintenance and Disease Avoidance in Animals
Nutricines and Nutrients, Health Maintenance and Disease Avoidance in Animals
Infectious diseases remain a major health challenge and are becoming increasingly difficult to ma... more Infectious diseases remain a major health challenge and are becoming increasingly difficult to manage due to the spread of antibiotic resistance. A novel approach is to exploit human milk oligosaccharides (HMOs), which are now known to reduce the prevalence of infectious diseases among breastfed infants. HMOs have bacteriostatic or bactericidal activity against a wide range of important pathogens, such as Streptococcus agalactiae (group B Streptococcus), Streptococcus pneumoniae, Campylobacter jejuni, Clostridioides difficile, Entamoeba histolytica and Candida albicans. Furthermore, HMOs can act synergistically with antibiotics, reducing the minimum inhibitory concentration for certain antibiotics by up to 32-fold. This could extend the therapeutic window of some antibiotics and also reduce the doses required to treat infectious diseases. Given the risk posed by the emergence of antibiotic-resistant pathogens, it would be advantageous to further exploit this synergism between antibi...
Cette invention concerne une formulation antioxydante qui peut se disperser facilement dans des m... more Cette invention concerne une formulation antioxydante qui peut se disperser facilement dans des matrices lipidiques a temperature ambiante sous l'effet d'un leger brassage. Cette formulation comprend un compose antioxydant phenolique, un excipient liquide, de preference un chelateur metallique, un emulsifiant, ainsi qu'un modificateur de polarite. Dans un mode de realisation prefere, une combinaison de composes antioxydants liposolubles et hydrosolubles est ajoutee afin qu'on obtienne un effet antioxydant renforce.
L'invention concerne un procede de conversion in situ de xanthophylles non libres en xanthoph... more L'invention concerne un procede de conversion in situ de xanthophylles non libres en xanthophylles libres dans la matiere vivante d'une plante. Ce procede consiste plus particulierement a liberer les xanthophylles par transesterification d'acyl-xanthophylles chez les vegetaux.
The microbiome is a large population of microorganisms in the gastrointestinal tract that plays a... more The microbiome is a large population of microorganisms in the gastrointestinal tract that plays an important role in health maintenance and disease avoidance. It develops in human infants immediately after birth and breast feeding is particularly advantageous because human milk contains various oligosaccharides (HMO) which are prebiotics that support establishment of the microbiome. The microbiome also has multiple effects in locations remote from the gastrointestinal tract. The recognition of the microbiome-gut-brain axis indicates that the microbiome plays a key role in brain functioning. It also influences immune regulation, the endocrine system, and the central nervous system. It is a target for therapeutic intervention for several health problems; gastrointestinal disorders, developmental indices such as cognition, anxiety, mood, and sociability and cancer therapy. Dietary components such as protein, fats, prebiotics, and polyphenols induce shifts in the microbiome. The close r...
International Review of Cytology
ABSTRACT Moisture content plays a role in seed physiology in two ways. First, it may convey infor... more ABSTRACT Moisture content plays a role in seed physiology in two ways. First, it may convey information about the expected metabolic activity of the seed—that is, development, resting, or germination. The proportion of structured or vicinal water in the tissue compared to the bulk water, and the change in absolute water content, may play a role here. A dehydration to air dryness would be necessary for the unequivocal switching of the water gradient polarity. This may explain why it is necessary to dry immature seeds below 60% moisture for good viability, even though germination occurs at 60% moisture. Therefore, the absolute moisture content does not dictate a specific physiological activity. Second, the expression of the perceived information is also controlled by moisture status. Severe dehydration irreversibly switches off production of reserve materials and switches on a controlled senescence program that continues at variable rates until the seed reserve structure is destroyed.
Biochimica et Biophysica Acta (BBA) - Enzymology
2. 2. Whole cells reduced NO 3 − to NO 2 − , NO and N 2 O when Na 2 S, Na 2 SO 3 , Na 2 S 2 O 3 o... more 2. 2. Whole cells reduced NO 3 − to NO 2 − , NO and N 2 O when Na 2 S, Na 2 SO 3 , Na 2 S 2 O 3 or Na 2 S 2 O 4 was the electron donor. The cell-free extract however only reduced NO 3 − to NO 2 − . ... 3. 3. Inhibitor effects suggest the involvement of an electron transport ...
Plant and Cell Physiology
Plant and Cell Physiology
Annals of Botany
Effect of light on auxin binding , cell fractionation and ultrastruc ture of etiolated soybean hy... more Effect of light on auxin binding , cell fractionation and ultrastruc ture of etiolated soybean hypo co tyls. Bot. Gaz. 141:149-156. Bajjalieh, N., J. H. Orf , T. Hymowitz and A. H. J ensen. 1980. Response of young chicks to raw, defatted Kunitz-trypsin inhibitor variant soybeans as sources of dietary protein. Poult. Sci. 59:328-332 .
Annals of Botany
... Rather, starch synthesis occurs in developing and germinating soya beans when there is high /... more ... Rather, starch synthesis occurs in developing and germinating soya beans when there is high /?-amylase activity (Adams et al., 1980). However, there is genetic variability of /?-amylase levels in soya beans. Gorman and Kiang (1974) found that the cultivar 'Chestnut' had very ...
Plant and Cell Physiology, Sep 1, 1982
EPC 2006 - 12th European Poultry Conference, Verona, Italy, 10-14 September, 2006., 2006
A model system was established to evaluate the ability of a pancreatic lipase enzyme to hydrolyse... more A model system was established to evaluate the ability of a pancreatic lipase enzyme to hydrolyse fats and oils, simulating lipid digestion in vitro. Lipid hydrolysis was monitored by quantification of the level of free fatty acids, mono-, di-and triglycerides. In the model system the pancreatic lipase was able to hydrolyse a non-oxidized fat quite rapidly. The activity of the lipase enzyme was severely inhibited by an oxidized oil, indicating that the oxidative status of the fat strongly influences lipid digestibility. In a second stage of the research the relationship between lipid quality and the digestibility was studied in more detail. Stabilization of the fat with antioxidants slowed down the oxidation process and maintained a high lipase activity. These tests directly confirm the beneficial effect of antioxidants to maintain the nutritional profile of the fat. This in vitro model system is a valuable tool to evaluate the digestibility of oils and fats as it may contribute additional information on the nutritional value of lipids used in the poultry industry.
Nutricines and Nutrients, Health Maintenance and Disease Avoidance in Animals
Nutricines and Nutrients, Health Maintenance and Disease Avoidance in Animals
Infectious diseases remain a major health challenge and are becoming increasingly difficult to ma... more Infectious diseases remain a major health challenge and are becoming increasingly difficult to manage due to the spread of antibiotic resistance. A novel approach is to exploit human milk oligosaccharides (HMOs), which are now known to reduce the prevalence of infectious diseases among breastfed infants. HMOs have bacteriostatic or bactericidal activity against a wide range of important pathogens, such as Streptococcus agalactiae (group B Streptococcus), Streptococcus pneumoniae, Campylobacter jejuni, Clostridioides difficile, Entamoeba histolytica and Candida albicans. Furthermore, HMOs can act synergistically with antibiotics, reducing the minimum inhibitory concentration for certain antibiotics by up to 32-fold. This could extend the therapeutic window of some antibiotics and also reduce the doses required to treat infectious diseases. Given the risk posed by the emergence of antibiotic-resistant pathogens, it would be advantageous to further exploit this synergism between antibi...
Cette invention concerne une formulation antioxydante qui peut se disperser facilement dans des m... more Cette invention concerne une formulation antioxydante qui peut se disperser facilement dans des matrices lipidiques a temperature ambiante sous l'effet d'un leger brassage. Cette formulation comprend un compose antioxydant phenolique, un excipient liquide, de preference un chelateur metallique, un emulsifiant, ainsi qu'un modificateur de polarite. Dans un mode de realisation prefere, une combinaison de composes antioxydants liposolubles et hydrosolubles est ajoutee afin qu'on obtienne un effet antioxydant renforce.
L'invention concerne un procede de conversion in situ de xanthophylles non libres en xanthoph... more L'invention concerne un procede de conversion in situ de xanthophylles non libres en xanthophylles libres dans la matiere vivante d'une plante. Ce procede consiste plus particulierement a liberer les xanthophylles par transesterification d'acyl-xanthophylles chez les vegetaux.
The microbiome is a large population of microorganisms in the gastrointestinal tract that plays a... more The microbiome is a large population of microorganisms in the gastrointestinal tract that plays an important role in health maintenance and disease avoidance. It develops in human infants immediately after birth and breast feeding is particularly advantageous because human milk contains various oligosaccharides (HMO) which are prebiotics that support establishment of the microbiome. The microbiome also has multiple effects in locations remote from the gastrointestinal tract. The recognition of the microbiome-gut-brain axis indicates that the microbiome plays a key role in brain functioning. It also influences immune regulation, the endocrine system, and the central nervous system. It is a target for therapeutic intervention for several health problems; gastrointestinal disorders, developmental indices such as cognition, anxiety, mood, and sociability and cancer therapy. Dietary components such as protein, fats, prebiotics, and polyphenols induce shifts in the microbiome. The close r...
International Review of Cytology
ABSTRACT Moisture content plays a role in seed physiology in two ways. First, it may convey infor... more ABSTRACT Moisture content plays a role in seed physiology in two ways. First, it may convey information about the expected metabolic activity of the seed—that is, development, resting, or germination. The proportion of structured or vicinal water in the tissue compared to the bulk water, and the change in absolute water content, may play a role here. A dehydration to air dryness would be necessary for the unequivocal switching of the water gradient polarity. This may explain why it is necessary to dry immature seeds below 60% moisture for good viability, even though germination occurs at 60% moisture. Therefore, the absolute moisture content does not dictate a specific physiological activity. Second, the expression of the perceived information is also controlled by moisture status. Severe dehydration irreversibly switches off production of reserve materials and switches on a controlled senescence program that continues at variable rates until the seed reserve structure is destroyed.
Biochimica et Biophysica Acta (BBA) - Enzymology
2. 2. Whole cells reduced NO 3 − to NO 2 − , NO and N 2 O when Na 2 S, Na 2 SO 3 , Na 2 S 2 O 3 o... more 2. 2. Whole cells reduced NO 3 − to NO 2 − , NO and N 2 O when Na 2 S, Na 2 SO 3 , Na 2 S 2 O 3 or Na 2 S 2 O 4 was the electron donor. The cell-free extract however only reduced NO 3 − to NO 2 − . ... 3. 3. Inhibitor effects suggest the involvement of an electron transport ...
Plant and Cell Physiology
Plant and Cell Physiology
Annals of Botany
Effect of light on auxin binding , cell fractionation and ultrastruc ture of etiolated soybean hy... more Effect of light on auxin binding , cell fractionation and ultrastruc ture of etiolated soybean hypo co tyls. Bot. Gaz. 141:149-156. Bajjalieh, N., J. H. Orf , T. Hymowitz and A. H. J ensen. 1980. Response of young chicks to raw, defatted Kunitz-trypsin inhibitor variant soybeans as sources of dietary protein. Poult. Sci. 59:328-332 .
Annals of Botany
... Rather, starch synthesis occurs in developing and germinating soya beans when there is high /... more ... Rather, starch synthesis occurs in developing and germinating soya beans when there is high /?-amylase activity (Adams et al., 1980). However, there is genetic variability of /?-amylase levels in soya beans. Gorman and Kiang (1974) found that the cultivar 'Chestnut' had very ...
Plant and Cell Physiology, Sep 1, 1982