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Papers by Alejandro Lavaque

Archives of Ophthalmology, May 1, 2006

Highlights of vitreoretina, Apr 17, 2023

<p>2A-B. Patient presenting with biomarkers for good visual outcome, who had early interven... more <p>2A-B. Patient presenting with biomarkers for good visual outcome, who had early intervention A. SD-OCT showing diffuse DME with subretinal fluid and intact inter-outer segment layer at baseline. B. 24 months after surgery complete resolution of intra- and subretinal fluid. 2C-D. Patient presenting without biomarkers for good visual outcome, who had late intervention. C. SD-OCT showing diffuse DME without subretinal fluid and damaged inter-outer segment layer at baseline. D. Persistent perifoveal intraretinal fluid and damaged inter-outer segment layer 24 months after surgery. Final CST measured <220 μm.</p

<p>Patients characteristics.</p

Protocols for chromatic pupil light reflex (PLR) testing considered mostly pulsed stimulation (pP... more Protocols for chromatic pupil light reflex (PLR) testing considered mostly pulsed stimulation (pPLR). A more sophisticated and promising technique is based on the PLR to flickering stimulation (fPLR). Our aim was to compare fPLR and pPLR parameters in order to validate fPLR paradigm. Two different experiments were carried out in young participants to compare parameters of chromatic pupillary measurements under flickering and pulsed conditions. We found that the fPLR amplitude parameter was significantly associated with pPLR transient constriction parameter. Also, for some conditions, typical pulse parameters can be identified directly in the fPLR recordings.

Highlights of Vitreoretina, 2022

In a fresh RD surgery, what technique would you use to identify a retinal hole or microtear if yo... more In a fresh RD surgery, what technique would you use to identify a retinal hole or microtear if you could not find it after looking for it?

Retinal Detachment Surgery and Proliferative Vitreoretinopathy, 2018

This PVR summary was performed after analysing 30 PVR questionnaires from expert vitreoretinal su... more This PVR summary was performed after analysing 30 PVR questionnaires from expert vitreoretinal surgeons. There are many tips and tricks shared by many of them despite they are referred to only one. I want to appreciate their kind collaboration with this chapter.

Investigative Ophthalmology & Visual Science, 2010

Investigative Ophthalmology & Visual Science, 2005

Investigative Ophthalmology & Visual Science, 2004

Ophthalmology Retina, 2019

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Ophthalmic Surgery, Lasers & Imaging, 2007

A review of the charts for all patients who developed large submacular hemorrhages following phot... more A review of the charts for all patients who developed large submacular hemorrhages following photodynamic therapy for choroidal neovascular membranes secondary to age-related macular degeneration yielded three patients who met the criteria for a large submacular hemorrhage. All three patients were treated for exudative age-related macular degeneration and were taking warfarin for chronic anticoagulation. Before photodynamic therapy, the international normalized ratio ranged from 1.2 to 1.6. All three patients had received at least one previous verteporfin treatment in the study eye. All three hemorrhages were not noted immediately after photodynamic therapy and were documented within 1 to 2 weeks following the procedure. Patients with age-related macular degeneration who are receiving warfarin therapy and undergoing repeat verteporfin treatments appear to be at risk for submacular hemorrhages.

PLOS ONE, 2018

We aimed to investigate biomarkers and predictive factors for visual and anatomical outcome in pa... more We aimed to investigate biomarkers and predictive factors for visual and anatomical outcome in patients with naïve diabetic macular edema (DME) who underwent small gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling as a first line treatment. Design Multicenter, retrospective, interventional study. Participants 120 eyes from 120 patients with naïve DME treated with PPV and ILM peeling with a follow up of 24 months. Methods Change in baseline best corrected visual acuity (BCVA) and central subfoveal thickness (CST) 1, 6, 12 and 24 months after surgery. Predictive value of baseline BCVA, CST, optical coherence tomography (OCT) features (presence of subretinal fluid (SRF) and photoreceptor damage), and time between DME diagnosis and surgery. Additional treatment for DME