ANDREW DAKA - Academia.edu (original) (raw)
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Papers by ANDREW DAKA
Sensors and Actuators A: Physical, 1997
In this paper we present the utilization of horizontally polarized surface acoustic waves for imm... more In this paper we present the utilization of horizontally polarized surface acoustic waves for immunosensing in liquids. We have used a du aldelay-line device on an LiTaO~ substrate working at 345 MHz to detect immunoglobulins of type G in phosphate buffer. The measurements are performed either using a 'droplet technique' with small amounts (5 tzl) of liquid, or in a flow-through cell. From the experimental results we derive a sensitivity of 112.5 kHz (ng mm-2)-~ and a detection limit of 35 pg for the absolute mass. We find a quadratic frequency dependence of the sensor signal, indicating a mass-loading effect.
Sensors and Actuators A: Physical, 1997
In this paper we present the utilization of horizontally polarized surface acoustic waves for imm... more In this paper we present the utilization of horizontally polarized surface acoustic waves for immunosensing in liquids. We have used a du aldelay-line device on an LiTaO~ substrate working at 345 MHz to detect immunoglobulins of type G in phosphate buffer. The measurements are performed either using a 'droplet technique' with small amounts (5 tzl) of liquid, or in a flow-through cell. From the experimental results we derive a sensitivity of 112.5 kHz (ng mm-2)-~ and a detection limit of 35 pg for the absolute mass. We find a quadratic frequency dependence of the sensor signal, indicating a mass-loading effect.