Aayushi jain - Academia.edu (original) (raw)
Papers by Aayushi jain
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
American Journal of Obstetrics and Gynecology, 2022
Journal of Food Science and Technology, 2022
The beet-root (Beta vulgaris) and whey powder together, can potentially use as a multifunctional ... more The beet-root (Beta vulgaris) and whey powder together, can potentially use as a multifunctional ingredient in the manufacturing of the “Popsicles”, due to their biochemical composition that can enhance the concentration of bioactive compounds. In the present study, beet-root juice concentrates were prepared at different time/temperature treatments viz 45 °C, 55 °C, and 65 °C for 120, 80 and 45 min. The effect of different time/temperature treatments on physicochemical composition, colour, antioxidant activity (%), bioactive compounds, spectral data and sensory acceptance were evaluated. The physicochemical parameters of popsicles (PTI, PT2, PT3) including protein, total phenols, betalain, radical scavenging activity %, colour and melting values were significantly affected (p ≤ 0.05) by the different time/temperature treatments. The concentration of betalain and protein in all the popsicles ranged from 1134 to 1299 mg/L and 1.92 to 1.54 g/100 g respectively. The reduction of bioactive components viz betacyanins, betaxanthins, betanin, oxalic and syringic acid was also observed in popsicle (PTI) as compared to control. Furthermore, popsicle (PT1) was prepared with beet-root juice concentrated at 45 °C showed maximum sensory acceptance. The physicochemical and organoleptic attributes of processed popsicles encourage the commercial usage of whey powder and concentrated beetroot juice.
— Due to the increasing importance of power electronics in control of devices particularly in ele... more — Due to the increasing importance of power electronics in control of devices particularly in electrical vehicles the reliability analysis becomes important. The reliability R�(t) of a component is the probability that this component will perform its intended function after a time ‘t’ in a given operating condition. Nowadays component reliability is not very important by considering only the power losses. For predicting reliability of power electronics components temperature and temperature cycle are to be determined.. The goal of this paper was to accurately simulate power loss and thermal behavior of a IGBT based Inverter using vendor data and a validated electrical model of a IGBT based VSI. Successful creation and implementation of these models can reduce the cost of design and production, increase reliability, quantify the accuracy of the estimated thermal impedance of an IGBT based VSI module, predict the maximum switching frequency without violating thermal limits,predict the...
Emerging Research in Computing, Information, Communication and Applications, 2019
This paper proposes a very novel approach to implement the automatic toll tax collection system o... more This paper proposes a very novel approach to implement the automatic toll tax collection system on the toll plazas using radio frequency identification (RFID) and global system for mobile (GSM). Nowadays, the cities and highways are bursting with traffic, and very often long queues of vehicles can be seen at various toll plazas so that they can pay the toll and then able to use the road or highway. So a system is proposed wherein the toll tax could be paid via cashless transactions and people wouldn’t have to wait for a long time for the cash payment of the toll tax. This would save people’s money and time simultaneously. It would also eliminate errors in cash transactions and further ease the job of the toll plaza companies. It would definitely bring down any of the corruptions occurring at the toll plazas. Finally, it would make the existing toll tax collection more efficient and ease our lives a bit more.
Data mining is a technology to explore, analyze (knowledge discovery from data) the data and At l... more Data mining is a technology to explore, analyze (knowledge discovery from data) the data and At last, extract the interesting (non-trivial, implicit, previously unknown and potentially useful) pattern or knowledge from huge amount of data. In this paper, we discuss about the problem in online mining of data in large transactional database, here we apply association rule for mining the data which helps to remove the redundant rule and helps in compact representation of rules for user. In this paper, optimized algorithm has been proposed for online rule generation. The advantage of this algorithm is that the graph generated in our algorithm has less edge as compared to the lattice used in the existing algorithm. This algorithm generated all the essential rules and no rule is missing. The use of non redundant association rules help significantly in the reduction of irrelevant noise in the data mining process.
Pressure induced structural phase transition of NaCl-type (B1) to CsCl-type (B2) structure in Sod... more Pressure induced structural phase transition of NaCl-type (B1) to CsCl-type (B2) structure in Sodium Chloride NaCl are presented. An effective interionic interaction potential (EIOP) with long range Coulomb, van der Waals (vdW) interaction and the short-range repulsive interaction upto second-neighbor ions within the Hafemeister and Flygare approach with modified ionic charge is reported here. The reckon value of the phase transition pressure (Pt) and the magnitude of the discontinuity in volume at the transition pressure are compatible as compared with reported data. The variations of elastic constants and their combinations with pressure follow ordered behavior. The present approach has also succeeded in predicting the Born and relative stability criteria.
AIP Conference Proceedings, 2018
In the last few decades the alkali halides emerged as crystals with useful applications and their... more In the last few decades the alkali halides emerged as crystals with useful applications and their high-pressure behaviour is the most intensively studied subject in high-pressure physics/chemistry, material science, and geosciences. Most alkali halides follow the B1 (NaCl-type)→B2 (CsCl-type) phase-transition route under pressure. In the present paper, we have investigated the characteristics of structural phase transition that occurred in Lithium Florid compound under high pressure. The transition pressure of B1-B2 was calculated using an effective interionic interaction potential (EIOP). The changes of the characteristics of crystals like, Gibbs free energy, cohesive energy, volume collapse, and lattice constant are calculated for the B1 and B2 structures. These data were compared with the available experimental and theoretical data.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2020
Background: Premature rupture of membranes (PROM) remains a subject of great clinical relevance. ... more Background: Premature rupture of membranes (PROM) remains a subject of great clinical relevance. The present study was conducted to study maternal morbidity and its relationship with PROM-delivery interval in patients with term PROM as compared to patients without PROM.Methods: A prospective case control study was conducted in the department of obstetrics and gynecology, Kasturba Hospital, New Delhi. 100 pregnant patients presenting to the labor room with features of PROM at term (POG>37 weeks) were taken as cases and 100 term pregnant women (age and parity matched) with intact membranes were taken as controls and compared in terms of maternal outcome.Results: This study reported maternal morbidity rate of 21% in term PROM cases which was significantly higher than in control group (5%). The major cause was febrile morbidity which occurred in 16% of cases indicating ascending infection. Other complications were abdominal and episiotomy wound infection (4%), chorioamnionitis (2%), ...
AIP Conference Proceedings, 2019
As well known, when many alkali halides, for example NaCl, KCl or RbCI, are subjected to high pre... more As well known, when many alkali halides, for example NaCl, KCl or RbCI, are subjected to high pressure, phase transformation take place in them with a marked decrease in specific volume and reconstruction of the crystal lattice from the NaC1-type to the CsC1-type structure (B1 to B2). This work is undertaken the effect of pressure on the crystal structure with incorporating effect of temperature for the first time. An effective interionic interaction potential (EIOP) includes long range Coulomb, van der Waals (vdW) interaction and the short-range repulsive interaction upto second-neighbor ions within the Hafemeister and Flygare approach with modified ionic charge. In this paper effect of temperature on phase transition make the EIOP model more suitable for calculating B1 to B2 phase transition.
AIP Conference Proceedings, 2019
A theoretical study of phase transition and various elastic constant using two body interaction m... more A theoretical study of phase transition and various elastic constant using two body interaction model is carried out. The calculated values of phase transition pressure and the vast volume discontinuity in pressure-volume (PV) phase diagram indicate the structural phase transition from rock salt (B1) to zinc blend (B2) structure of potassium chloride (KCl) and Potassium Bromide (KBr). Fair agreement with lattice theoretical data calculated from an interaction potential model composed of Coulomb force, van der Walls force and first and second nearest neighbor repulsive forces is found. The present calculation have revealed good agreement with the available experimental data on the phase transition pressures (5 and 10 GPa). On the basis of Born's stability criteria the relations between the pressure dependence of the bulk modulus (B T), shear moduli (C 44) and tetragonal moduli (C S) to the B1-B2 transition are also investigated.
Materials Today: Proceedings, 2020
NaMgF 3 is a nearly tissue equivalent material with low Z eff = 10.4 and a well-known phosphor fo... more NaMgF 3 is a nearly tissue equivalent material with low Z eff = 10.4 and a well-known phosphor for its high sensitivity concerning luminescence. The type of preparation route followed greatly affects the luminescence efficiency of a material. Grinding of NaMgF 3 :Tb phosphor for a long time induces several lattice defects in the phosphor. In this work, effect of particle size on TL/OSL response of NaMgF 3 :Tb irradiated by 60 Co source of gamma radiations with a dose of 15 Gy has been investigated. NaMgF 3 :Tb samples has been synthesized by solid state reaction method using different grinding times i.e. 1 h and 5 h. XRD technique confirms its formation and crystallite size is calculated. TL studies show that sample synthesized by 5 h grinding is almost 2 times more intense than the sample obtained by 1 h grinding. Also, a clear enhancement is seen in the shoulder peak of sample grinded for 5 h. This could be due to increase in occupancy of trapped charge carriers in the trap levels. However, the position of main TL glow peak remains same in both the samples. Associated TL kinetic parameters such as order of kinetics, activation energy, frequency factor and trap density have been calculated by deconvoluting the TL glow peaks to understand the TL phenomenon. Continuous-wave optically stimulated luminescence (CW-OSL) decay curves have been obtained under blue LED stimulation for 40 s. Analyzing the CW-OSL decay curves reveal that grinding time significantly affects the OSL intensity of the phosphor as well. The decay constant and photoionization cross-section is determined for the faster and slower components of the total OSL intensity. It could be concluded that the time of grinding taken during preparation of the material has a major role in affecting the concentration of trap levels formed inside the forbidden gap of the phosphor.
Journal of Luminescence, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Oncomedicine, 2018
Background: Cisplatin is considered as the crucial regimen of widely prescribed chemotherapy trea... more Background: Cisplatin is considered as the crucial regimen of widely prescribed chemotherapy treatment to many cancer types. However, incessant increasing dose of cisplatin against many cancers including cervical cancer is known for drug resistance and side effects like nephrotoxicity and ototoxicity. Methods: To address above problems, this paper reports using ATM kinase inhibitor (KU55933) and siRNA DNA ligase III to alter the DNA repair response in vitro low dose cisplatin treated HeLa cells. Here, authors performed cell proliferation, MTT cell cytotoxicity, annexin V/PI staining flow cytometery and PI stained cell cycle assays to substantiate observations. Results: This paper reports that low dose cisplatin (10 µM) can show better effects in vitro growing HeLa cells in combination with KU55933. However, we included siRNA DNA ligase III along with KU55933, but data suggest that the level of DNA ligase III protein are not changed due to treatment with siRNA DNA ligase III as shown by immunocytochemistry assay. Even though, level of DNA ligase III is not altered in the present finding, use of KU55933 as combinatorial option with low dose cisplatin produce significant anti-proliferation effects (up to 35%) and also loss of cell viability including apoptotic cell death (up to 30%) in treated HeLa cells. Conclusion: This study suggests that KU55933 in combination with low dose cisplatin may be a good option to bring anti-proliferation and loss of viability in HeLa cells and may be explored in other cancer cell lines as well.
International Journal of Trend in Scientific Research and Development, 2018
The efficiency of marketing for soft commodities in India has been of significant concern in the ... more The efficiency of marketing for soft commodities in India has been of significant concern in the recent years. Out of 370 million tons of fruit production in the world, India accounts for 30 million tons. Over the last decade, the area under horticulture g 2.7% per annum and annual production increased by 7%. With today's era of digitization, the dealer, farmers, wholesaler of soft commodities are maintaining the Expense Management, Accounting, Purchase Management, etc. manually and which is t consuming with no transparency, this in return creating major problem for trading. So, focusing on the above problem definition, we propose an ERP based system for major category of people involved in soft commodities, which has merits over current system in practice. The proposed system will have features like SMS facility, managing wholesale business. Managing orders/sale, Purchases with accounting facility along with various business report formats based on individual requirements. This will help stakeholders to understand trading details of their soft commodities.
Breast Cancer Research and Treatment, 2019
Highlights d The MTH1 inhibitor TH588 synergizes with Plk1 inhibition to drive cancer cell death ... more Highlights d The MTH1 inhibitor TH588 synergizes with Plk1 inhibition to drive cancer cell death d VISAGE implicates the mitotic spindle, not MTH1, as the target of drug synergy d TH588 binds the colchicine binding site of b-tubulin blocking microtubule assembly d The cancer cell spindle is particularly vulnerable to Plk1 + microtubule inhibitors
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
American Journal of Obstetrics and Gynecology, 2022
Journal of Food Science and Technology, 2022
The beet-root (Beta vulgaris) and whey powder together, can potentially use as a multifunctional ... more The beet-root (Beta vulgaris) and whey powder together, can potentially use as a multifunctional ingredient in the manufacturing of the “Popsicles”, due to their biochemical composition that can enhance the concentration of bioactive compounds. In the present study, beet-root juice concentrates were prepared at different time/temperature treatments viz 45 °C, 55 °C, and 65 °C for 120, 80 and 45 min. The effect of different time/temperature treatments on physicochemical composition, colour, antioxidant activity (%), bioactive compounds, spectral data and sensory acceptance were evaluated. The physicochemical parameters of popsicles (PTI, PT2, PT3) including protein, total phenols, betalain, radical scavenging activity %, colour and melting values were significantly affected (p ≤ 0.05) by the different time/temperature treatments. The concentration of betalain and protein in all the popsicles ranged from 1134 to 1299 mg/L and 1.92 to 1.54 g/100 g respectively. The reduction of bioactive components viz betacyanins, betaxanthins, betanin, oxalic and syringic acid was also observed in popsicle (PTI) as compared to control. Furthermore, popsicle (PT1) was prepared with beet-root juice concentrated at 45 °C showed maximum sensory acceptance. The physicochemical and organoleptic attributes of processed popsicles encourage the commercial usage of whey powder and concentrated beetroot juice.
— Due to the increasing importance of power electronics in control of devices particularly in ele... more — Due to the increasing importance of power electronics in control of devices particularly in electrical vehicles the reliability analysis becomes important. The reliability R�(t) of a component is the probability that this component will perform its intended function after a time ‘t’ in a given operating condition. Nowadays component reliability is not very important by considering only the power losses. For predicting reliability of power electronics components temperature and temperature cycle are to be determined.. The goal of this paper was to accurately simulate power loss and thermal behavior of a IGBT based Inverter using vendor data and a validated electrical model of a IGBT based VSI. Successful creation and implementation of these models can reduce the cost of design and production, increase reliability, quantify the accuracy of the estimated thermal impedance of an IGBT based VSI module, predict the maximum switching frequency without violating thermal limits,predict the...
Emerging Research in Computing, Information, Communication and Applications, 2019
This paper proposes a very novel approach to implement the automatic toll tax collection system o... more This paper proposes a very novel approach to implement the automatic toll tax collection system on the toll plazas using radio frequency identification (RFID) and global system for mobile (GSM). Nowadays, the cities and highways are bursting with traffic, and very often long queues of vehicles can be seen at various toll plazas so that they can pay the toll and then able to use the road or highway. So a system is proposed wherein the toll tax could be paid via cashless transactions and people wouldn’t have to wait for a long time for the cash payment of the toll tax. This would save people’s money and time simultaneously. It would also eliminate errors in cash transactions and further ease the job of the toll plaza companies. It would definitely bring down any of the corruptions occurring at the toll plazas. Finally, it would make the existing toll tax collection more efficient and ease our lives a bit more.
Data mining is a technology to explore, analyze (knowledge discovery from data) the data and At l... more Data mining is a technology to explore, analyze (knowledge discovery from data) the data and At last, extract the interesting (non-trivial, implicit, previously unknown and potentially useful) pattern or knowledge from huge amount of data. In this paper, we discuss about the problem in online mining of data in large transactional database, here we apply association rule for mining the data which helps to remove the redundant rule and helps in compact representation of rules for user. In this paper, optimized algorithm has been proposed for online rule generation. The advantage of this algorithm is that the graph generated in our algorithm has less edge as compared to the lattice used in the existing algorithm. This algorithm generated all the essential rules and no rule is missing. The use of non redundant association rules help significantly in the reduction of irrelevant noise in the data mining process.
Pressure induced structural phase transition of NaCl-type (B1) to CsCl-type (B2) structure in Sod... more Pressure induced structural phase transition of NaCl-type (B1) to CsCl-type (B2) structure in Sodium Chloride NaCl are presented. An effective interionic interaction potential (EIOP) with long range Coulomb, van der Waals (vdW) interaction and the short-range repulsive interaction upto second-neighbor ions within the Hafemeister and Flygare approach with modified ionic charge is reported here. The reckon value of the phase transition pressure (Pt) and the magnitude of the discontinuity in volume at the transition pressure are compatible as compared with reported data. The variations of elastic constants and their combinations with pressure follow ordered behavior. The present approach has also succeeded in predicting the Born and relative stability criteria.
AIP Conference Proceedings, 2018
In the last few decades the alkali halides emerged as crystals with useful applications and their... more In the last few decades the alkali halides emerged as crystals with useful applications and their high-pressure behaviour is the most intensively studied subject in high-pressure physics/chemistry, material science, and geosciences. Most alkali halides follow the B1 (NaCl-type)→B2 (CsCl-type) phase-transition route under pressure. In the present paper, we have investigated the characteristics of structural phase transition that occurred in Lithium Florid compound under high pressure. The transition pressure of B1-B2 was calculated using an effective interionic interaction potential (EIOP). The changes of the characteristics of crystals like, Gibbs free energy, cohesive energy, volume collapse, and lattice constant are calculated for the B1 and B2 structures. These data were compared with the available experimental and theoretical data.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2020
Background: Premature rupture of membranes (PROM) remains a subject of great clinical relevance. ... more Background: Premature rupture of membranes (PROM) remains a subject of great clinical relevance. The present study was conducted to study maternal morbidity and its relationship with PROM-delivery interval in patients with term PROM as compared to patients without PROM.Methods: A prospective case control study was conducted in the department of obstetrics and gynecology, Kasturba Hospital, New Delhi. 100 pregnant patients presenting to the labor room with features of PROM at term (POG>37 weeks) were taken as cases and 100 term pregnant women (age and parity matched) with intact membranes were taken as controls and compared in terms of maternal outcome.Results: This study reported maternal morbidity rate of 21% in term PROM cases which was significantly higher than in control group (5%). The major cause was febrile morbidity which occurred in 16% of cases indicating ascending infection. Other complications were abdominal and episiotomy wound infection (4%), chorioamnionitis (2%), ...
AIP Conference Proceedings, 2019
As well known, when many alkali halides, for example NaCl, KCl or RbCI, are subjected to high pre... more As well known, when many alkali halides, for example NaCl, KCl or RbCI, are subjected to high pressure, phase transformation take place in them with a marked decrease in specific volume and reconstruction of the crystal lattice from the NaC1-type to the CsC1-type structure (B1 to B2). This work is undertaken the effect of pressure on the crystal structure with incorporating effect of temperature for the first time. An effective interionic interaction potential (EIOP) includes long range Coulomb, van der Waals (vdW) interaction and the short-range repulsive interaction upto second-neighbor ions within the Hafemeister and Flygare approach with modified ionic charge. In this paper effect of temperature on phase transition make the EIOP model more suitable for calculating B1 to B2 phase transition.
AIP Conference Proceedings, 2019
A theoretical study of phase transition and various elastic constant using two body interaction m... more A theoretical study of phase transition and various elastic constant using two body interaction model is carried out. The calculated values of phase transition pressure and the vast volume discontinuity in pressure-volume (PV) phase diagram indicate the structural phase transition from rock salt (B1) to zinc blend (B2) structure of potassium chloride (KCl) and Potassium Bromide (KBr). Fair agreement with lattice theoretical data calculated from an interaction potential model composed of Coulomb force, van der Walls force and first and second nearest neighbor repulsive forces is found. The present calculation have revealed good agreement with the available experimental data on the phase transition pressures (5 and 10 GPa). On the basis of Born's stability criteria the relations between the pressure dependence of the bulk modulus (B T), shear moduli (C 44) and tetragonal moduli (C S) to the B1-B2 transition are also investigated.
Materials Today: Proceedings, 2020
NaMgF 3 is a nearly tissue equivalent material with low Z eff = 10.4 and a well-known phosphor fo... more NaMgF 3 is a nearly tissue equivalent material with low Z eff = 10.4 and a well-known phosphor for its high sensitivity concerning luminescence. The type of preparation route followed greatly affects the luminescence efficiency of a material. Grinding of NaMgF 3 :Tb phosphor for a long time induces several lattice defects in the phosphor. In this work, effect of particle size on TL/OSL response of NaMgF 3 :Tb irradiated by 60 Co source of gamma radiations with a dose of 15 Gy has been investigated. NaMgF 3 :Tb samples has been synthesized by solid state reaction method using different grinding times i.e. 1 h and 5 h. XRD technique confirms its formation and crystallite size is calculated. TL studies show that sample synthesized by 5 h grinding is almost 2 times more intense than the sample obtained by 1 h grinding. Also, a clear enhancement is seen in the shoulder peak of sample grinded for 5 h. This could be due to increase in occupancy of trapped charge carriers in the trap levels. However, the position of main TL glow peak remains same in both the samples. Associated TL kinetic parameters such as order of kinetics, activation energy, frequency factor and trap density have been calculated by deconvoluting the TL glow peaks to understand the TL phenomenon. Continuous-wave optically stimulated luminescence (CW-OSL) decay curves have been obtained under blue LED stimulation for 40 s. Analyzing the CW-OSL decay curves reveal that grinding time significantly affects the OSL intensity of the phosphor as well. The decay constant and photoionization cross-section is determined for the faster and slower components of the total OSL intensity. It could be concluded that the time of grinding taken during preparation of the material has a major role in affecting the concentration of trap levels formed inside the forbidden gap of the phosphor.
Journal of Luminescence, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Oncomedicine, 2018
Background: Cisplatin is considered as the crucial regimen of widely prescribed chemotherapy trea... more Background: Cisplatin is considered as the crucial regimen of widely prescribed chemotherapy treatment to many cancer types. However, incessant increasing dose of cisplatin against many cancers including cervical cancer is known for drug resistance and side effects like nephrotoxicity and ototoxicity. Methods: To address above problems, this paper reports using ATM kinase inhibitor (KU55933) and siRNA DNA ligase III to alter the DNA repair response in vitro low dose cisplatin treated HeLa cells. Here, authors performed cell proliferation, MTT cell cytotoxicity, annexin V/PI staining flow cytometery and PI stained cell cycle assays to substantiate observations. Results: This paper reports that low dose cisplatin (10 µM) can show better effects in vitro growing HeLa cells in combination with KU55933. However, we included siRNA DNA ligase III along with KU55933, but data suggest that the level of DNA ligase III protein are not changed due to treatment with siRNA DNA ligase III as shown by immunocytochemistry assay. Even though, level of DNA ligase III is not altered in the present finding, use of KU55933 as combinatorial option with low dose cisplatin produce significant anti-proliferation effects (up to 35%) and also loss of cell viability including apoptotic cell death (up to 30%) in treated HeLa cells. Conclusion: This study suggests that KU55933 in combination with low dose cisplatin may be a good option to bring anti-proliferation and loss of viability in HeLa cells and may be explored in other cancer cell lines as well.
International Journal of Trend in Scientific Research and Development, 2018
The efficiency of marketing for soft commodities in India has been of significant concern in the ... more The efficiency of marketing for soft commodities in India has been of significant concern in the recent years. Out of 370 million tons of fruit production in the world, India accounts for 30 million tons. Over the last decade, the area under horticulture g 2.7% per annum and annual production increased by 7%. With today's era of digitization, the dealer, farmers, wholesaler of soft commodities are maintaining the Expense Management, Accounting, Purchase Management, etc. manually and which is t consuming with no transparency, this in return creating major problem for trading. So, focusing on the above problem definition, we propose an ERP based system for major category of people involved in soft commodities, which has merits over current system in practice. The proposed system will have features like SMS facility, managing wholesale business. Managing orders/sale, Purchases with accounting facility along with various business report formats based on individual requirements. This will help stakeholders to understand trading details of their soft commodities.
Breast Cancer Research and Treatment, 2019
Highlights d The MTH1 inhibitor TH588 synergizes with Plk1 inhibition to drive cancer cell death ... more Highlights d The MTH1 inhibitor TH588 synergizes with Plk1 inhibition to drive cancer cell death d VISAGE implicates the mitotic spindle, not MTH1, as the target of drug synergy d TH588 binds the colchicine binding site of b-tubulin blocking microtubule assembly d The cancer cell spindle is particularly vulnerable to Plk1 + microtubule inhibitors