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Papers by Fany Anggun Abadi

Research paper thumbnail of The Role of Women in the Recovery Process of International Peace and Security in Burundi, Central Africa

Research paper thumbnail of The Influence of Indo-Pacific Economic Framework on Peace Stability in The ASEAN Region

Jurnal Global & Strategis

By taking into account all motives for foreign economic cooperation, including the Indo-Pacific E... more By taking into account all motives for foreign economic cooperation, including the Indo-Pacific Economics Framework (IPEF), this framework will definitely affect the economies of several countries in the region, especially Southeast Asia. ASEAN is demanded not only as an elite state organization but furthermore, is also required to have the capability to involve all elements of its member countries’ societies, in the varying fields, especially economic, political and peace stability. This paper then raised a question regarding how does the IPEF influence the peace stability in the ASEAN Region. In examining this question, the author used the theory of international organizations typology, international economic regime theory, and regional peace stability theory. It is concluded that the step that’s certainly must be taken by countries in the region is to help each other. Thus, it is the joint responsibility of each country, both inside and outside the region to prevent the emergence...

Research paper thumbnail of Kepentingan Nasional Suriah Dalam Upaya Penyelesaian Konflik Bersenjata di Idlib, Suriah dari tahun 2016-2017

Jurnal ICMES

Abstrak Pertempuran di Idlib tahun 2016-2017 di bawah pemerintahan Bashar Al-Assad dan bagaimana ... more Abstrak Pertempuran di Idlib tahun 2016-2017 di bawah pemerintahan Bashar Al-Assad dan bagaimana pengaruhnya terhadap kepentingan nasional Suriah. Konflik sipil di Suriah yang diakibatkan oleh Arab spring hampir memasuki tahun ke-10, menyisakkan Idlib sebagai palang pintu terakhir. Keterlibatan aktor-aktor asing memberikan indikasi akan kompleksnya konflik di Suriah. penulis mendapatkan rumusan masalah berupa: Kepentingan Nasional Dalam Upaya Penyelesaian Konflik Bersenjata di Idlib, Suriah dari tahun 2016-2017. Tujuan dari penelitian ini adalah untuk mengetahui relevansi pertempuran di Idlib dengan keamanan nasional Suriah. Penelitian ini dilakukan dengan metode kualitatif dengan menggunakan pendekatan analisis deskriptif dan teknik pengumpulan data sekunder yang diperoleh melalui studi kepustakaan dalam hal ini bersumber dari buku, serta artikel jurnal. Selanjutnya, konsep kepentingan nasional diposisikan sebagai alat analisis dalam pertempuran Idlib, dimana salah satu aspek yang ...

Research paper thumbnail of Indonesia's Foreign Policy in Marine Defense Strategy in The Indo-Pacific

Technium Social Sciences Journal

In the global interaction with the Indo-Pacific order which is dominated by dynamic contestation ... more In the global interaction with the Indo-Pacific order which is dominated by dynamic contestation issues, the Indo-Pacific system stipulates that Indonesia created the Indo-Pacific concept to advance the habit of inclusivity for dialogue with regional settlements to create peace through building blocks in the region. The author formulates the formulation of the problem in the form of: the development of Indonesia's foreign policy in the strategy of inter-state resilience in the Indo-Pacific region. The purpose of this article is to discuss the Indo-Pacific Integration Project as Indonesia's foreign policy sustainability strategy and provide recommendations for implementation at various levels, including strategic, bilateral and practical levels. The author uses Barry Buzan's national security system and foreign policy theory, namely neo-realism, with the concept of national interest and foreign policy analysis. The role of the military is limited to the capabilities of de...

Research paper thumbnail of Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women

PLoS ONE, 2009

Advancements in animal models and cell culture techniques have been invaluable in the elucidation... more Advancements in animal models and cell culture techniques have been invaluable in the elucidation of the molecular mechanisms that regulate muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine changes in global gene transcription during immobilization-induced muscle atrophy in humans and then explore the effects of the most prominent transcriptional alterations on protein expression and function. Healthy men and women (N = 24) were subjected to two weeks of unilateral limb immobilization, with muscle biopsies obtained before, after 48 hours (48 H) and 14 days (14 D) of immobilization. Muscle cross sectional area (,5%) and strength (10-20%) were significantly reduced in men and women (,5% and 10-20%, respectively) after 14 D of immobilization. Micro-array analyses of total RNA extracted from biopsy samples at 48 H and 14 D uncovered 575 and 3,128 probes, respectively, which were significantly altered during immobilization. As a group, genes involved in mitochondrial bioenergetics and carbohydrate metabolism were predominant features at both 48 H and 14 D, with genes involved in protein synthesis and degradation significantly down-regulated and up-regulated, respectively, at 14 D of muscle atrophy. There was also a significant decrease in the protein content of mitochondrial cytochrome c oxidase, and the enzyme activity of cytochrome c oxidase and citrate synthase after 14 D of immobilization. Furthermore, protein ubiquitination was significantly increased at 48 H but not 14 D of immobilization. These results suggest that transcriptional and post-transcriptional suppression of mitochondrial processes is sustained throughout 14 D of immobilization, while protein ubiquitination plays an early but transient role in muscle atrophy following short-term immobilization in humans.

Research paper thumbnail of Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women

PloS one, 2009

Advancements in animal models and cell culture techniques have been invaluable in the elucidation... more Advancements in animal models and cell culture techniques have been invaluable in the elucidation of the molecular mechanisms that regulate muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine changes in global gene transcription during immobilization-induced muscle atrophy in humans and then explore the effects of the most prominent transcriptional alterations on protein expression and function. Healthy men and women (N = 24) were subjected to two weeks of unilateral limb immobilization, with muscle biopsies obtained before, after 48 hours (48 H) and 14 days (14 D) of immobilization. Muscle cross sectional area (,5%) and strength (10-20%) were significantly reduced in men and women (,5% and 10-20%, respectively) after 14 D of immobilization. Micro-array analyses of total RNA extracted from biopsy samples at 48 H and 14 D uncovered 575 and 3,128 probes, respectively, which were significantly altered during immobilization. As a group, genes involved in mitochondrial bioenergetics and carbohydrate metabolism were predominant features at both 48 H and 14 D, with genes involved in protein synthesis and degradation significantly down-regulated and up-regulated, respectively, at 14 D of muscle atrophy. There was also a significant decrease in the protein content of mitochondrial cytochrome c oxidase, and the enzyme activity of cytochrome c oxidase and citrate synthase after 14 D of immobilization. Furthermore, protein ubiquitination was significantly increased at 48 H but not 14 D of immobilization. These results suggest that transcriptional and post-transcriptional suppression of mitochondrial processes is sustained throughout 14 D of immobilization, while protein ubiquitination plays an early but transient role in muscle atrophy following short-term immobilization in humans.

Research paper thumbnail of The Role of Women in the Recovery Process of International Peace and Security in Burundi, Central Africa

Research paper thumbnail of The Influence of Indo-Pacific Economic Framework on Peace Stability in The ASEAN Region

Jurnal Global & Strategis

By taking into account all motives for foreign economic cooperation, including the Indo-Pacific E... more By taking into account all motives for foreign economic cooperation, including the Indo-Pacific Economics Framework (IPEF), this framework will definitely affect the economies of several countries in the region, especially Southeast Asia. ASEAN is demanded not only as an elite state organization but furthermore, is also required to have the capability to involve all elements of its member countries’ societies, in the varying fields, especially economic, political and peace stability. This paper then raised a question regarding how does the IPEF influence the peace stability in the ASEAN Region. In examining this question, the author used the theory of international organizations typology, international economic regime theory, and regional peace stability theory. It is concluded that the step that’s certainly must be taken by countries in the region is to help each other. Thus, it is the joint responsibility of each country, both inside and outside the region to prevent the emergence...

Research paper thumbnail of Kepentingan Nasional Suriah Dalam Upaya Penyelesaian Konflik Bersenjata di Idlib, Suriah dari tahun 2016-2017

Jurnal ICMES

Abstrak Pertempuran di Idlib tahun 2016-2017 di bawah pemerintahan Bashar Al-Assad dan bagaimana ... more Abstrak Pertempuran di Idlib tahun 2016-2017 di bawah pemerintahan Bashar Al-Assad dan bagaimana pengaruhnya terhadap kepentingan nasional Suriah. Konflik sipil di Suriah yang diakibatkan oleh Arab spring hampir memasuki tahun ke-10, menyisakkan Idlib sebagai palang pintu terakhir. Keterlibatan aktor-aktor asing memberikan indikasi akan kompleksnya konflik di Suriah. penulis mendapatkan rumusan masalah berupa: Kepentingan Nasional Dalam Upaya Penyelesaian Konflik Bersenjata di Idlib, Suriah dari tahun 2016-2017. Tujuan dari penelitian ini adalah untuk mengetahui relevansi pertempuran di Idlib dengan keamanan nasional Suriah. Penelitian ini dilakukan dengan metode kualitatif dengan menggunakan pendekatan analisis deskriptif dan teknik pengumpulan data sekunder yang diperoleh melalui studi kepustakaan dalam hal ini bersumber dari buku, serta artikel jurnal. Selanjutnya, konsep kepentingan nasional diposisikan sebagai alat analisis dalam pertempuran Idlib, dimana salah satu aspek yang ...

Research paper thumbnail of Indonesia's Foreign Policy in Marine Defense Strategy in The Indo-Pacific

Technium Social Sciences Journal

In the global interaction with the Indo-Pacific order which is dominated by dynamic contestation ... more In the global interaction with the Indo-Pacific order which is dominated by dynamic contestation issues, the Indo-Pacific system stipulates that Indonesia created the Indo-Pacific concept to advance the habit of inclusivity for dialogue with regional settlements to create peace through building blocks in the region. The author formulates the formulation of the problem in the form of: the development of Indonesia's foreign policy in the strategy of inter-state resilience in the Indo-Pacific region. The purpose of this article is to discuss the Indo-Pacific Integration Project as Indonesia's foreign policy sustainability strategy and provide recommendations for implementation at various levels, including strategic, bilateral and practical levels. The author uses Barry Buzan's national security system and foreign policy theory, namely neo-realism, with the concept of national interest and foreign policy analysis. The role of the military is limited to the capabilities of de...

Research paper thumbnail of Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women

PLoS ONE, 2009

Advancements in animal models and cell culture techniques have been invaluable in the elucidation... more Advancements in animal models and cell culture techniques have been invaluable in the elucidation of the molecular mechanisms that regulate muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine changes in global gene transcription during immobilization-induced muscle atrophy in humans and then explore the effects of the most prominent transcriptional alterations on protein expression and function. Healthy men and women (N = 24) were subjected to two weeks of unilateral limb immobilization, with muscle biopsies obtained before, after 48 hours (48 H) and 14 days (14 D) of immobilization. Muscle cross sectional area (,5%) and strength (10-20%) were significantly reduced in men and women (,5% and 10-20%, respectively) after 14 D of immobilization. Micro-array analyses of total RNA extracted from biopsy samples at 48 H and 14 D uncovered 575 and 3,128 probes, respectively, which were significantly altered during immobilization. As a group, genes involved in mitochondrial bioenergetics and carbohydrate metabolism were predominant features at both 48 H and 14 D, with genes involved in protein synthesis and degradation significantly down-regulated and up-regulated, respectively, at 14 D of muscle atrophy. There was also a significant decrease in the protein content of mitochondrial cytochrome c oxidase, and the enzyme activity of cytochrome c oxidase and citrate synthase after 14 D of immobilization. Furthermore, protein ubiquitination was significantly increased at 48 H but not 14 D of immobilization. These results suggest that transcriptional and post-transcriptional suppression of mitochondrial processes is sustained throughout 14 D of immobilization, while protein ubiquitination plays an early but transient role in muscle atrophy following short-term immobilization in humans.

Research paper thumbnail of Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women

PloS one, 2009

Advancements in animal models and cell culture techniques have been invaluable in the elucidation... more Advancements in animal models and cell culture techniques have been invaluable in the elucidation of the molecular mechanisms that regulate muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine changes in global gene transcription during immobilization-induced muscle atrophy in humans and then explore the effects of the most prominent transcriptional alterations on protein expression and function. Healthy men and women (N = 24) were subjected to two weeks of unilateral limb immobilization, with muscle biopsies obtained before, after 48 hours (48 H) and 14 days (14 D) of immobilization. Muscle cross sectional area (,5%) and strength (10-20%) were significantly reduced in men and women (,5% and 10-20%, respectively) after 14 D of immobilization. Micro-array analyses of total RNA extracted from biopsy samples at 48 H and 14 D uncovered 575 and 3,128 probes, respectively, which were significantly altered during immobilization. As a group, genes involved in mitochondrial bioenergetics and carbohydrate metabolism were predominant features at both 48 H and 14 D, with genes involved in protein synthesis and degradation significantly down-regulated and up-regulated, respectively, at 14 D of muscle atrophy. There was also a significant decrease in the protein content of mitochondrial cytochrome c oxidase, and the enzyme activity of cytochrome c oxidase and citrate synthase after 14 D of immobilization. Furthermore, protein ubiquitination was significantly increased at 48 H but not 14 D of immobilization. These results suggest that transcriptional and post-transcriptional suppression of mitochondrial processes is sustained throughout 14 D of immobilization, while protein ubiquitination plays an early but transient role in muscle atrophy following short-term immobilization in humans.