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Papers by Ebtesam Abdulla

Research paper thumbnail of Meningeal Tumors (General Principles)

Research paper thumbnail of 461 Outcomes and Healthcare Utilization of Adult Spinal Cord Injury Associated With Time to Surgery: An Analysis of the National Trauma Data Bank (NTDB): 2019-2021

Neurosurgery/Neurosurgery online, Apr 1, 2024

Research paper thumbnail of 160 Gamme Knife Radio Surgery for Cerebral Arteriovenous Malformation (AVM) in Children: A Systematic Review and Meta-analysis of Clinical Outcomes

Neurosurgery/Neurosurgery online, Apr 1, 2024

Research paper thumbnail of Letter to the Editor. Decoding GBM: a singular insight into the precision of 5-ALA through single-cell analysis

Journal of neurosurgery, Feb 1, 2024

Research paper thumbnail of C2 versus C3 or C4 as the upper instrumented vertebra for long-segment cervical fusions: a systematic review and meta-analysis

Journal of neurosurgery, Nov 30, 2023

Research paper thumbnail of Immunoglobulin G4-related disease masquerading an epidural spinal cord tumor: a case report

Research paper thumbnail of Depression and anxiety associated with COVID- 19 pandemic among healthcare professionals in India- A systematic review and meta-analysis

Clinical Epidemiology and Global Health, 2021

Research paper thumbnail of Clinical outcomes and complication profile of total hip arthroplasty after lumbar spine fusion: a meta-analysis and systematic review

European Spine Journal, 2019

Research paper thumbnail of Biportal endoscopic surgery for lumbar spine herniated discs: a narrative review of its clinical application and outcomes

Annals of Medicine & Surgery

Lumbar disk herniation (LDH) is a common condition affecting millions worldwide. The management o... more Lumbar disk herniation (LDH) is a common condition affecting millions worldwide. The management of LDH has evolved over the years, with the development of newer surgical techniques that aim to provide better outcomes with minimal invasiveness. One promising emerging technique is biportal endoscopic spinal surgery (BESS), which utilizes specialized endoscopic equipment to treat LDH through two small incisions. This review aims to assess the effectiveness of BESS as a management option for LDH by analyzing the available literature on surgical outcomes and potential complications associated with the technique. Our review shows that BESS is associated with favorable postoperative results as judged by clinical scoring systems, such as visual analog scale, Oswestry disability index, and MacNab criteria. BESS has several advantages over traditional open surgery, including minimized blood loss, a shorter duration of hospitalization, and an expedited healing process. However, the technique h...

Research paper thumbnail of Blister-like Cerebral Aneurysm after Endovascular Catheterization: A Case Report and Literature Review

Research paper thumbnail of Harassment in Academic Medicine: One Hundred Years of Solitude

Nepal Journal of Neuroscience

There are dozens of cases of harassment and bullying in academic medicine that are hidden in the ... more There are dozens of cases of harassment and bullying in academic medicine that are hidden in the most hidden drawers. Harassment in academic medicine is an accepted and widely recognized problem. As a common pattern, the protagonists are always someone with power against people with a lower hierarchy. Abuse in any of its forms, be it physical, moral, or academic, ends up affecting the student's performance and behavior. It should be considered an unacceptable and punishable pattern in any academic setting.

Research paper thumbnail of Haemorrhagic progression of contusions after traumatic brain injury in orally anticoagulated patient

DOAJ (DOAJ: Directory of Open Access Journals), Sep 1, 2022

Traumatic brain injury carries a high risk of neurological disability and fatality 1-8. The exten... more Traumatic brain injury carries a high risk of neurological disability and fatality 1-8. The extent of the injury to the neuronal tissue following a head impact defines the primary injury. The acceleration energy delivered at the time of impact provokes this injury. There are numerous secondary responses to the injury that mostly intensify the primary injury. When a head impact causes a contusion, the hemorrhagic injury frequently progresses over the first few hours after impact, either growing or developing new, non-contiguous hemorrhagic lesions, a condition known as the hemorrhagic progression of a contusion 1,2,4,7,9-14. ILLUSTRATED CASE An 88-year-old woman was admitted with a severe headache, multiple emetic episodes, and a brief loss of consciousness after falling while doing housework. Her past medical history included anticoagulation with warfarin for atrial fibrillation (international normalized ratio (INR): 3.75). She had normal vital signs and a grossly intact neurological examination on admission. A cranial computed tomography (CT) scan was performed 45 minutes after arrival to the emergency department, which revealed small bifrontal contusions (Fig 1). It was decided to transfer her to the intermediate care unit with non-invasive hemodynamic monitoring, analgesia, continuous neurological evaluation, and neurosurgical evaluation. At 18 hours, she started

Research paper thumbnail of Chemotherapy

Research paper thumbnail of Indications for Fusion With Intradural Spine Tumor Resection in Adults: A Systematic Review and Meta-analysis

Research paper thumbnail of Cooperative Sedation in Moderate Traumatic Brain Injury: A Tool for Neurocritical Care Management

Journal of Neurointensive Care

Research paper thumbnail of Decompressive Laparotomy as a Treatment Option for Refractory Intracranial Hypertension in Patients With Traumatic Brain Injury: A Systematic Review

Journal of Neurointensive Care

Background: Researchers investigated the role of decompressive laparotomy as a novel technique to... more Background: Researchers investigated the role of decompressive laparotomy as a novel technique to improve the outcome of refractory intracranial hypertension in patients with severe Traumatic brain injury (TBI). In this paper, we conduct a systematic review of the literature and discuss the existing information on the role of decompressive laparotomy in patients with severe TBI. Methods: A search for RCT, not RCT, prospective and retrospective cohort studies will be carried out through electronic databases. The strategy comprised topic headings (MeSH) such as "Decompressive laparotomy," "traumatic brain damage," "Neurocritical care," and "intracranial hypertension," as well as text words related to Booleans terms. The following data were retrieved individually and separately: mortality, functional independence (modified Rankin scale 0 to 2, or Glasgow Prognostic Scale with a score of 4 or above), and intracranial pressure value before and afte...

Research paper thumbnail of Supraorbital vs pterional keyhole for anterior circulation aneurysms: A systematic review and meta-analysis

Research paper thumbnail of Neurogenically Originated Inflammatory Response Syndrome: Role in the Neurocritical Patient

Journal of Neurointensive Care

The systemic inflammatory response syndrome (SIRS) consists of an inflammatory phenomenon as a re... more The systemic inflammatory response syndrome (SIRS) consists of an inflammatory phenomenon as a response of the immune system against infections, as well as non-infectious injuries, which includes manifestations that affect multiple organs, among which hyperthermia or hypothermia, leukopenia or leukocytosis, tachycardia, and tachypnea. SIRS accompanies different acute brain and spinal cord injuries, including subarachnoid hemorrhage, intracerebral hemorrhage, spinal cord trauma, traumatic brain injury, and status epilepticus. We suggest a new term for this condition neurogenically originated systemic inflammatory response syndrome (NoSIRS). NIRS can be considered a new syndrome associated with pathological neurological conditions. However, more research is needed to figure out the true severity of this clinical picture and also figure out the best way to treat this condition.

Research paper thumbnail of A solitary case of gliosarcoma an indication for TP53 mutation analysis: a non-concordant finding

Romanian Neurosurgery, 2021

Background: Li-Fraumeni syndrome (LFS) is a hereditary, autosomal dominant malignancy predisposit... more Background: Li-Fraumeni syndrome (LFS) is a hereditary, autosomal dominant malignancy predisposition induced by a mutant TP53. Here, we describe a gliosarcoma (GS) case with a clinical family history impressive for an LFS case in the absence of inherited germline TP53 mutations. Case description: We present a 44-year-old female with a right high parietal mass. The mass proved pathologically to be GS with an isocitrate dehydrogenase-1 (IDH1) mutation. Pedigree analysis identified five first-degree and second-degree relatives with LFS spectrum malignancies. The patient tested positive for TP53 mutation; however, her family tested negative. Conclusion: Of all the tumours, GSs are the least described entity with LFS. We are highlighting the need to do a genetic survey in family members of the patient who has been diagnosed to have gliosarcoma and other tumours consistent with LFS.

Research paper thumbnail of Tremor as a symptom of degenerative cervical myelopathy: a systematic review

British Journal of Neurosurgery, 2022

BACKGROUND AO Spine RECODE-DCM (Research objectives and common data elements for degenerative cer... more BACKGROUND AO Spine RECODE-DCM (Research objectives and common data elements for degenerative cervical myelopathy) has highlighted that the subjective disability reported by people living with DCM is much broader than routinely considered today by most professionals. This includes a description of tremor. The objective of this review was to study the incidence and possible aetiology of tremor in degenerative cervical myelopathy (DCM). METHODS A systematic review registered in PROSPERO (CRD42020176905) was conducted in Embase and MEDLINE for papers studying tremor and DCM published on or before the 20th of July 2020. All manuscripts describing an association between tremor and DCM in humans were included. Articles relating to non-human animals, and those not available in English were excluded. An analysis was conducted in accordance with PRISMA and SWiM guidelines for systematic reviews. RESULTS Out of a total of 4402 screened abstracts, we identified 7 case reports and series describing tremor in 9 DCM patients. Papers were divided into three groups for the discussion. The first group includes DCM correctly identified on presentation, with tremor as a described symptom. The second group includes cases where DCM was misdiagnosed, often as Parkinson's disease. The third group includes a single case with a previous history of DCM, presenting with an otherwise unexplained tremor. This grouping allows for the clustering of cases supporting various arguments for the association between tremor and DCM. CONCLUSION DCM can be associated with tremor. The current evidence is restricted to case series. Further study is warranted to establish tremor prevalence, and its significance to assessment and management.

Research paper thumbnail of Meningeal Tumors (General Principles)

Research paper thumbnail of 461 Outcomes and Healthcare Utilization of Adult Spinal Cord Injury Associated With Time to Surgery: An Analysis of the National Trauma Data Bank (NTDB): 2019-2021

Neurosurgery/Neurosurgery online, Apr 1, 2024

Research paper thumbnail of 160 Gamme Knife Radio Surgery for Cerebral Arteriovenous Malformation (AVM) in Children: A Systematic Review and Meta-analysis of Clinical Outcomes

Neurosurgery/Neurosurgery online, Apr 1, 2024

Research paper thumbnail of Letter to the Editor. Decoding GBM: a singular insight into the precision of 5-ALA through single-cell analysis

Journal of neurosurgery, Feb 1, 2024

Research paper thumbnail of C2 versus C3 or C4 as the upper instrumented vertebra for long-segment cervical fusions: a systematic review and meta-analysis

Journal of neurosurgery, Nov 30, 2023

Research paper thumbnail of Immunoglobulin G4-related disease masquerading an epidural spinal cord tumor: a case report

Research paper thumbnail of Depression and anxiety associated with COVID- 19 pandemic among healthcare professionals in India- A systematic review and meta-analysis

Clinical Epidemiology and Global Health, 2021

Research paper thumbnail of Clinical outcomes and complication profile of total hip arthroplasty after lumbar spine fusion: a meta-analysis and systematic review

European Spine Journal, 2019

Research paper thumbnail of Biportal endoscopic surgery for lumbar spine herniated discs: a narrative review of its clinical application and outcomes

Annals of Medicine & Surgery

Lumbar disk herniation (LDH) is a common condition affecting millions worldwide. The management o... more Lumbar disk herniation (LDH) is a common condition affecting millions worldwide. The management of LDH has evolved over the years, with the development of newer surgical techniques that aim to provide better outcomes with minimal invasiveness. One promising emerging technique is biportal endoscopic spinal surgery (BESS), which utilizes specialized endoscopic equipment to treat LDH through two small incisions. This review aims to assess the effectiveness of BESS as a management option for LDH by analyzing the available literature on surgical outcomes and potential complications associated with the technique. Our review shows that BESS is associated with favorable postoperative results as judged by clinical scoring systems, such as visual analog scale, Oswestry disability index, and MacNab criteria. BESS has several advantages over traditional open surgery, including minimized blood loss, a shorter duration of hospitalization, and an expedited healing process. However, the technique h...

Research paper thumbnail of Blister-like Cerebral Aneurysm after Endovascular Catheterization: A Case Report and Literature Review

Research paper thumbnail of Harassment in Academic Medicine: One Hundred Years of Solitude

Nepal Journal of Neuroscience

There are dozens of cases of harassment and bullying in academic medicine that are hidden in the ... more There are dozens of cases of harassment and bullying in academic medicine that are hidden in the most hidden drawers. Harassment in academic medicine is an accepted and widely recognized problem. As a common pattern, the protagonists are always someone with power against people with a lower hierarchy. Abuse in any of its forms, be it physical, moral, or academic, ends up affecting the student's performance and behavior. It should be considered an unacceptable and punishable pattern in any academic setting.

Research paper thumbnail of Haemorrhagic progression of contusions after traumatic brain injury in orally anticoagulated patient

DOAJ (DOAJ: Directory of Open Access Journals), Sep 1, 2022

Traumatic brain injury carries a high risk of neurological disability and fatality 1-8. The exten... more Traumatic brain injury carries a high risk of neurological disability and fatality 1-8. The extent of the injury to the neuronal tissue following a head impact defines the primary injury. The acceleration energy delivered at the time of impact provokes this injury. There are numerous secondary responses to the injury that mostly intensify the primary injury. When a head impact causes a contusion, the hemorrhagic injury frequently progresses over the first few hours after impact, either growing or developing new, non-contiguous hemorrhagic lesions, a condition known as the hemorrhagic progression of a contusion 1,2,4,7,9-14. ILLUSTRATED CASE An 88-year-old woman was admitted with a severe headache, multiple emetic episodes, and a brief loss of consciousness after falling while doing housework. Her past medical history included anticoagulation with warfarin for atrial fibrillation (international normalized ratio (INR): 3.75). She had normal vital signs and a grossly intact neurological examination on admission. A cranial computed tomography (CT) scan was performed 45 minutes after arrival to the emergency department, which revealed small bifrontal contusions (Fig 1). It was decided to transfer her to the intermediate care unit with non-invasive hemodynamic monitoring, analgesia, continuous neurological evaluation, and neurosurgical evaluation. At 18 hours, she started

Research paper thumbnail of Chemotherapy

Research paper thumbnail of Indications for Fusion With Intradural Spine Tumor Resection in Adults: A Systematic Review and Meta-analysis

Research paper thumbnail of Cooperative Sedation in Moderate Traumatic Brain Injury: A Tool for Neurocritical Care Management

Journal of Neurointensive Care

Research paper thumbnail of Decompressive Laparotomy as a Treatment Option for Refractory Intracranial Hypertension in Patients With Traumatic Brain Injury: A Systematic Review

Journal of Neurointensive Care

Background: Researchers investigated the role of decompressive laparotomy as a novel technique to... more Background: Researchers investigated the role of decompressive laparotomy as a novel technique to improve the outcome of refractory intracranial hypertension in patients with severe Traumatic brain injury (TBI). In this paper, we conduct a systematic review of the literature and discuss the existing information on the role of decompressive laparotomy in patients with severe TBI. Methods: A search for RCT, not RCT, prospective and retrospective cohort studies will be carried out through electronic databases. The strategy comprised topic headings (MeSH) such as "Decompressive laparotomy," "traumatic brain damage," "Neurocritical care," and "intracranial hypertension," as well as text words related to Booleans terms. The following data were retrieved individually and separately: mortality, functional independence (modified Rankin scale 0 to 2, or Glasgow Prognostic Scale with a score of 4 or above), and intracranial pressure value before and afte...

Research paper thumbnail of Supraorbital vs pterional keyhole for anterior circulation aneurysms: A systematic review and meta-analysis

Research paper thumbnail of Neurogenically Originated Inflammatory Response Syndrome: Role in the Neurocritical Patient

Journal of Neurointensive Care

The systemic inflammatory response syndrome (SIRS) consists of an inflammatory phenomenon as a re... more The systemic inflammatory response syndrome (SIRS) consists of an inflammatory phenomenon as a response of the immune system against infections, as well as non-infectious injuries, which includes manifestations that affect multiple organs, among which hyperthermia or hypothermia, leukopenia or leukocytosis, tachycardia, and tachypnea. SIRS accompanies different acute brain and spinal cord injuries, including subarachnoid hemorrhage, intracerebral hemorrhage, spinal cord trauma, traumatic brain injury, and status epilepticus. We suggest a new term for this condition neurogenically originated systemic inflammatory response syndrome (NoSIRS). NIRS can be considered a new syndrome associated with pathological neurological conditions. However, more research is needed to figure out the true severity of this clinical picture and also figure out the best way to treat this condition.

Research paper thumbnail of A solitary case of gliosarcoma an indication for TP53 mutation analysis: a non-concordant finding

Romanian Neurosurgery, 2021

Background: Li-Fraumeni syndrome (LFS) is a hereditary, autosomal dominant malignancy predisposit... more Background: Li-Fraumeni syndrome (LFS) is a hereditary, autosomal dominant malignancy predisposition induced by a mutant TP53. Here, we describe a gliosarcoma (GS) case with a clinical family history impressive for an LFS case in the absence of inherited germline TP53 mutations. Case description: We present a 44-year-old female with a right high parietal mass. The mass proved pathologically to be GS with an isocitrate dehydrogenase-1 (IDH1) mutation. Pedigree analysis identified five first-degree and second-degree relatives with LFS spectrum malignancies. The patient tested positive for TP53 mutation; however, her family tested negative. Conclusion: Of all the tumours, GSs are the least described entity with LFS. We are highlighting the need to do a genetic survey in family members of the patient who has been diagnosed to have gliosarcoma and other tumours consistent with LFS.

Research paper thumbnail of Tremor as a symptom of degenerative cervical myelopathy: a systematic review

British Journal of Neurosurgery, 2022

BACKGROUND AO Spine RECODE-DCM (Research objectives and common data elements for degenerative cer... more BACKGROUND AO Spine RECODE-DCM (Research objectives and common data elements for degenerative cervical myelopathy) has highlighted that the subjective disability reported by people living with DCM is much broader than routinely considered today by most professionals. This includes a description of tremor. The objective of this review was to study the incidence and possible aetiology of tremor in degenerative cervical myelopathy (DCM). METHODS A systematic review registered in PROSPERO (CRD42020176905) was conducted in Embase and MEDLINE for papers studying tremor and DCM published on or before the 20th of July 2020. All manuscripts describing an association between tremor and DCM in humans were included. Articles relating to non-human animals, and those not available in English were excluded. An analysis was conducted in accordance with PRISMA and SWiM guidelines for systematic reviews. RESULTS Out of a total of 4402 screened abstracts, we identified 7 case reports and series describing tremor in 9 DCM patients. Papers were divided into three groups for the discussion. The first group includes DCM correctly identified on presentation, with tremor as a described symptom. The second group includes cases where DCM was misdiagnosed, often as Parkinson's disease. The third group includes a single case with a previous history of DCM, presenting with an otherwise unexplained tremor. This grouping allows for the clustering of cases supporting various arguments for the association between tremor and DCM. CONCLUSION DCM can be associated with tremor. The current evidence is restricted to case series. Further study is warranted to establish tremor prevalence, and its significance to assessment and management.