Abdullah Qamar - Academia.edu (original) (raw)

Papers by Abdullah Qamar

Pakistan Armed Forces Medical Journal

Objective: To assess the ameliorative effects of Prolotherapy on the pain score of the gait cycle... more Objective: To assess the ameliorative effects of Prolotherapy on the pain score of the gait cycle in Monosodium Iodoacetate (MIA) induced osteoarthritis in the rat knee joint. Study Design: Laboratory-based experimental study. Place and Duration of Study: Department of Anatomy, Army Medical College, Rawalpindi in collaboration with the National Institute of Health (NIH), Islamabad and Pathology Lab Pak Emirates Rawalpindi, Pakistan, from Aug to Nov 2021. Methodology: Thirty male Sprague Dawley rats were randomly divided into three groups (n=10 in each group). The control group was Group-A. To induce osteoarthritic changes in Group-B, a single dose of 1mg Monosodium Iodoacetate was injected intra-articularly into the right knee. Group-C received a single dose of 1mg Monosodium Iodoacetate injection in the right knee intra articularly to induce osteoarthritic changes, and was followed by 0.1ml Prolotherapy (3ml of 25% dextrose, 2ml of 2% Xylocaine, 1ml of injection thiamine, and 1ml o...

European Journal of Anatomy, 2022

The aim of the study was to determine the effects of immobilization on the gross morphology of ra... more The aim of the study was to determine the effects of immobilization on the gross morphology of rats’ intervertebral disc (IVD) and observe the ameliorating effects of Omega 3 fatty acids and Co-enzyme Q 10 (CoQ10). Forty Sprague Dawley rats weighing 250-300 g were procured from NIH Islamabad. The animals were randomly selected and were divided into four groups of 10 animals in each. Group-A rats served as control group. Each rat of Group B was disc immobilized by using an Illizarov-type apparatus, which was applied for 60 days. Group-C and -D rats after disc immobilization were administrated with Omega 3 fatty acids (260 mg/kg/day) and CoQ10 (150mg/kg/day) through oral gavage respectively. Gross examination of IVD was done using the Thompson grading scale and the disc alterations were scored from grade 1 to 5 in increasing order of IVD alterations. Gross examination of the sections of IVD’s of the control group showed normal healthy morphology, falling in Thompson grade I degenerati...

Pakistan Armed Forces Medical Journal, 2018

Objective: To observe the destructive effects of low frequency noise on periodontium with special... more Objective: To observe the destructive effects of low frequency noise on periodontium with special emphasis on the alveolar bone. Study Design: Laboratory based randomized control study. Place and Duration of Study: The study was conducted at Anatomy department of Army Medical College, Rawalpindi, in collaboration with animal house of National Institute of Health, Islamabad. The study continued for one year, from Sep 2012 to Aug 2013. Material and Methods: Thirty adult BALB mice were divided into three equal groups. The animals from group A (Control) were exposed to routine outside environment of animal house with normal daily activity going on. The animals from experimental group B were kept in an environment having complete silence with no exposure to external environment. The animals from group C (Experimental) were exposed to low frequency noise of 200 Hz continuously for a period of three months. This sound was generated by an analogue frequency generator having uninterrupted po...

Pakistan Armed Forces Medical Journal, 2019

Objective: To determine correlation between the Prothrombin time obtained by Prothrombin time met... more Objective: To determine correlation between the Prothrombin time obtained by Prothrombin time meter with Prothrombin time estimation by clinical laboratory in neonates. Study Design: Cross sectional study. Place and Duration of Study: Study was conducted in the department of Paediatrics, Combined Military Hospital Lahore, from Feb 2014 to Aug 2014. Methodology: One hundred cases, comprising of infants between the age from 0 to 28 days of both genders fulfilling the inclusion and exclusion criteria, were included in the study after seeking written informed consent. Blood samples from all selected neonates were obtained from a peripheral vein under strict aseptic conditions. The samples were analyzed on Sysmex Coagulation Analyzer CA-500 from the Pathology Department. Simultaneously a drop of blood was obtained by heel prick and spot checked by Roche Coaguchek Prothrombin Time Meter. SPSS version 17 was used for data analysis. Percentage and frequency were calculated for the qualitati...

Journal of the Pakistan Medical Association, 2021

Objective of study: The objective of the study is to identify the attitudes of medical students t... more Objective of study: The objective of the study is to identify the attitudes of medical students towards the clinical importance of embryology. Methodology: The cross-sectional questionnaire-based survey was conducted at a private medical college of Sialkot, Islam Medical College from September 2019 to November 2019. Ethical approval was obtained from the Institutional Research and Ethics Committee prior to the study. Hundred First year and 100 final year medical students of Islam Medical College, participated in the survey. Thurdstone and Chave attitude analysis scoring was used to assess the attitudes. The questionnaire consisted of 20 statements. Students had to tick only those statements with which they were in full agreement. Prior to conducting the study a median score was taken out of 50 anatomy teachers, showing their opinion toward each statement. Results: The results of the study showed that the medical students do appreciate the importance of embryology in the early years...

Pakistan Armed Forces Medical Journal, 2019

Objective: To determine the important clinical features at the initial presentation of Hepatocell... more Objective: To determine the important clinical features at the initial presentation of Hepatocellular carcinoma and the treatments offered thereby. Study Design: Cross-sectional study. Place and Duration of Study: Department of Gastroenterology, Pak Emirates Military Hospital, Rawalpindi, from Jan 2017 to Dec 2017. Methodology: A total of 157 patients were studied. Their history, examination and relevant investigations were carried out at initial presentation to find all required details including age, gender, etiology of HCC, number and size of hepatic lesions, Child Pugh class, performance status, BCLC scoring, vascular invasion of tumor, lymph nodal involvement and metastasis; at time of diagnosis of hepatocellular carcinoma. Treatment was offered based on all these parameters, as per latest AASLD guidelines. Data were entered in SPSS version 24 for statistical analysis. Results: Of the total 157 patients, 117 (75%) were males and 40 (25%) were females. Mean age was 60.4 ± 8.67 y...

Objective: To study cisplatin induced genotoxicity in reticulocytes and colonic epithelial cells ... more Objective: To study cisplatin induced genotoxicity in reticulocytes and colonic epithelial cells of male Sprague Dawley rats. Study Design: Randomized controlled trial. Place and Duration of Study: Study was conducted at Department of Physiology, Army Medical College, Rawalpindi from Oct 2014 to Apr 2016. Methodology: Trial was conducted on sixty male Sprague Dawley rats having average age 80-90 days and weight 250±50 grams. Rats were randomly allocated into two groups with 30 rats each. Rats in group I were administered intraperitoneal normal saline 10 ml/kg body weight twice a week for 4 weeks whereas rats in group II received intraperitoneal cisplatin 2 mg/kg body weight twice a week for 4 weeks. After 4 weeks, animals were sacrificed and blood sample was obtained for evaluation of serum malondialdehyde and micronucleated reticulocytes. After collection of blood sample, rats were dissected and small part of colon was excised and studied for micronucleated colonic epithelial cell...

Pakistan Armed Forces Medical Journal, 2019

Objective: To study the gross morphology of skeletal muscles and plasma Creatinine phosphokinase ... more Objective: To study the gross morphology of skeletal muscles and plasma Creatinine phosphokinase levels of rats and find effect of long acting β2-agonists co-administration in Statin induced myopathies. Study Design: Quasi experimental study. Place and Duration of Study: Department of Anatomy, Army Medical College Rawalpindi in collaboration with National Institute of Health (NIH) Islamabad and Armed forces institute of Pathology (AFIP) Rawalpindi, from Jan 2015 to Jun 2016. Methodology: Adult male Sprague-Dawley rats were procured from NIH Islamabad. Their average approximate age was 70-80 days with weight range 250 ± 50 grams. The animals were randomly selected and divided into three groups. Group A was the control. Each rat of group B received Simvastatin dissolved in distilled water, by oral gavage (60mg/kg/day) once daily, for 12 weeks. Animals of Group C received simvastatin dissolved in distilled water, (60mg/kg/day) once daily plus for dissolved in distilled water (3μg/kg/da...

Pakistan Armed Forces Medical Journal

Objective: To assess the ameliorative effects of Prolotherapy on the pain score of the gait cycle... more Objective: To assess the ameliorative effects of Prolotherapy on the pain score of the gait cycle in Monosodium Iodoacetate (MIA) induced osteoarthritis in the rat knee joint. Study Design: Laboratory-based experimental study. Place and Duration of Study: Department of Anatomy, Army Medical College, Rawalpindi in collaboration with the National Institute of Health (NIH), Islamabad and Pathology Lab Pak Emirates Rawalpindi, Pakistan, from Aug to Nov 2021. Methodology: Thirty male Sprague Dawley rats were randomly divided into three groups (n=10 in each group). The control group was Group-A. To induce osteoarthritic changes in Group-B, a single dose of 1mg Monosodium Iodoacetate was injected intra-articularly into the right knee. Group-C received a single dose of 1mg Monosodium Iodoacetate injection in the right knee intra articularly to induce osteoarthritic changes, and was followed by 0.1ml Prolotherapy (3ml of 25% dextrose, 2ml of 2% Xylocaine, 1ml of injection thiamine, and 1ml o...

European Journal of Anatomy, 2022

The aim of the study was to determine the effects of immobilization on the gross morphology of ra... more The aim of the study was to determine the effects of immobilization on the gross morphology of rats’ intervertebral disc (IVD) and observe the ameliorating effects of Omega 3 fatty acids and Co-enzyme Q 10 (CoQ10). Forty Sprague Dawley rats weighing 250-300 g were procured from NIH Islamabad. The animals were randomly selected and were divided into four groups of 10 animals in each. Group-A rats served as control group. Each rat of Group B was disc immobilized by using an Illizarov-type apparatus, which was applied for 60 days. Group-C and -D rats after disc immobilization were administrated with Omega 3 fatty acids (260 mg/kg/day) and CoQ10 (150mg/kg/day) through oral gavage respectively. Gross examination of IVD was done using the Thompson grading scale and the disc alterations were scored from grade 1 to 5 in increasing order of IVD alterations. Gross examination of the sections of IVD’s of the control group showed normal healthy morphology, falling in Thompson grade I degenerati...

Pakistan Armed Forces Medical Journal, 2018

Objective: To observe the destructive effects of low frequency noise on periodontium with special... more Objective: To observe the destructive effects of low frequency noise on periodontium with special emphasis on the alveolar bone. Study Design: Laboratory based randomized control study. Place and Duration of Study: The study was conducted at Anatomy department of Army Medical College, Rawalpindi, in collaboration with animal house of National Institute of Health, Islamabad. The study continued for one year, from Sep 2012 to Aug 2013. Material and Methods: Thirty adult BALB mice were divided into three equal groups. The animals from group A (Control) were exposed to routine outside environment of animal house with normal daily activity going on. The animals from experimental group B were kept in an environment having complete silence with no exposure to external environment. The animals from group C (Experimental) were exposed to low frequency noise of 200 Hz continuously for a period of three months. This sound was generated by an analogue frequency generator having uninterrupted po...

Pakistan Armed Forces Medical Journal, 2019

Objective: To determine correlation between the Prothrombin time obtained by Prothrombin time met... more Objective: To determine correlation between the Prothrombin time obtained by Prothrombin time meter with Prothrombin time estimation by clinical laboratory in neonates. Study Design: Cross sectional study. Place and Duration of Study: Study was conducted in the department of Paediatrics, Combined Military Hospital Lahore, from Feb 2014 to Aug 2014. Methodology: One hundred cases, comprising of infants between the age from 0 to 28 days of both genders fulfilling the inclusion and exclusion criteria, were included in the study after seeking written informed consent. Blood samples from all selected neonates were obtained from a peripheral vein under strict aseptic conditions. The samples were analyzed on Sysmex Coagulation Analyzer CA-500 from the Pathology Department. Simultaneously a drop of blood was obtained by heel prick and spot checked by Roche Coaguchek Prothrombin Time Meter. SPSS version 17 was used for data analysis. Percentage and frequency were calculated for the qualitati...

Journal of the Pakistan Medical Association, 2021

Objective of study: The objective of the study is to identify the attitudes of medical students t... more Objective of study: The objective of the study is to identify the attitudes of medical students towards the clinical importance of embryology. Methodology: The cross-sectional questionnaire-based survey was conducted at a private medical college of Sialkot, Islam Medical College from September 2019 to November 2019. Ethical approval was obtained from the Institutional Research and Ethics Committee prior to the study. Hundred First year and 100 final year medical students of Islam Medical College, participated in the survey. Thurdstone and Chave attitude analysis scoring was used to assess the attitudes. The questionnaire consisted of 20 statements. Students had to tick only those statements with which they were in full agreement. Prior to conducting the study a median score was taken out of 50 anatomy teachers, showing their opinion toward each statement. Results: The results of the study showed that the medical students do appreciate the importance of embryology in the early years...

Pakistan Armed Forces Medical Journal, 2019

Objective: To determine the important clinical features at the initial presentation of Hepatocell... more Objective: To determine the important clinical features at the initial presentation of Hepatocellular carcinoma and the treatments offered thereby. Study Design: Cross-sectional study. Place and Duration of Study: Department of Gastroenterology, Pak Emirates Military Hospital, Rawalpindi, from Jan 2017 to Dec 2017. Methodology: A total of 157 patients were studied. Their history, examination and relevant investigations were carried out at initial presentation to find all required details including age, gender, etiology of HCC, number and size of hepatic lesions, Child Pugh class, performance status, BCLC scoring, vascular invasion of tumor, lymph nodal involvement and metastasis; at time of diagnosis of hepatocellular carcinoma. Treatment was offered based on all these parameters, as per latest AASLD guidelines. Data were entered in SPSS version 24 for statistical analysis. Results: Of the total 157 patients, 117 (75%) were males and 40 (25%) were females. Mean age was 60.4 ± 8.67 y...

Objective: To study cisplatin induced genotoxicity in reticulocytes and colonic epithelial cells ... more Objective: To study cisplatin induced genotoxicity in reticulocytes and colonic epithelial cells of male Sprague Dawley rats. Study Design: Randomized controlled trial. Place and Duration of Study: Study was conducted at Department of Physiology, Army Medical College, Rawalpindi from Oct 2014 to Apr 2016. Methodology: Trial was conducted on sixty male Sprague Dawley rats having average age 80-90 days and weight 250±50 grams. Rats were randomly allocated into two groups with 30 rats each. Rats in group I were administered intraperitoneal normal saline 10 ml/kg body weight twice a week for 4 weeks whereas rats in group II received intraperitoneal cisplatin 2 mg/kg body weight twice a week for 4 weeks. After 4 weeks, animals were sacrificed and blood sample was obtained for evaluation of serum malondialdehyde and micronucleated reticulocytes. After collection of blood sample, rats were dissected and small part of colon was excised and studied for micronucleated colonic epithelial cell...

Pakistan Armed Forces Medical Journal, 2019

Objective: To study the gross morphology of skeletal muscles and plasma Creatinine phosphokinase ... more Objective: To study the gross morphology of skeletal muscles and plasma Creatinine phosphokinase levels of rats and find effect of long acting β2-agonists co-administration in Statin induced myopathies. Study Design: Quasi experimental study. Place and Duration of Study: Department of Anatomy, Army Medical College Rawalpindi in collaboration with National Institute of Health (NIH) Islamabad and Armed forces institute of Pathology (AFIP) Rawalpindi, from Jan 2015 to Jun 2016. Methodology: Adult male Sprague-Dawley rats were procured from NIH Islamabad. Their average approximate age was 70-80 days with weight range 250 ± 50 grams. The animals were randomly selected and divided into three groups. Group A was the control. Each rat of group B received Simvastatin dissolved in distilled water, by oral gavage (60mg/kg/day) once daily, for 12 weeks. Animals of Group C received simvastatin dissolved in distilled water, (60mg/kg/day) once daily plus for dissolved in distilled water (3μg/kg/da...