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Papers by Abdulmalik Aliyu

Journal of Basic and Social Pharmacy, 2024

Nigerian Journal of Pharmaceutical Research, Apr 8, 2024

A-research concept and design; B-collection and/or assembly of data; C-data analysis and interpre... more A-research concept and design; B-collection and/or assembly of data; C-data analysis and interpretation; D-writing the article; E-critical revision of the article; F-final approval of article.

Bayero Journal of Pure and Applied Sciences, 2020

All over the world, hundreds of plants have been identified based on researchers and experimental... more All over the world, hundreds of plants have been identified based on researchers and experimental evidence as good sources of medicinal agents. The bioactive components (phytochemicals) of both the seeds and pulp of Cola milleni were extracted using ethanol as solvent. The bioactive components detected were alkaloids, tanins, saponins, cardiac glycosides, carbohydrates, sterols, resins and terpenes while Flavonoids, anthraquinones, anthracyanides and phenol were not detected for both the seed and pulps. Antimicrobial activity of the ethanol extract (Seed and pulp) against Staphylococcus aureus, Escherichia coli and Penicillium notatum was carried out using standard techniques. Staphylococcus aureus had the highest zone of inhibition for pulp having a range of 9.7mm±0.58mm - 19.7mm±2.52mm while Penicllium notatum had the least with 0.00mm. S.aureus also had the highest zone of inhibition range of 14.3mm±2.08mm - 21.3mm±1.53mm for the seed extract while penicillium had the least inhib...

Background: River Lavun, located near Bida is a source of domestic water for the populace. Fish f... more Background: River Lavun, located near Bida is a source of domestic water for the populace. Fish from this river is consumed by general populace. Polluted river water contaminates its fish, it is therefore, necessary to evaluate bacteriological and elemental quality of fish from this river which have been reported earlier to be polluted.Objective: To evaluate the bacteriological and elemental quality of fish from River Lavun, with a view of assessing its potential health hazard.Methodology: Three live cat fish (Clarias gariepinus) were obtained from River Lavun monthly for six months for analyses. Using standard methods, microbial load was determined, while susceptibility profiles of the identified isolates was obtained using disc diffusion technique. Elemental contents of the fish were determined using atomic absorption spectrophotometer.Results: Heterotrophic plate counts ranged from 1.5±0.3 to 5.4±0.6×105 (cfu/g) while faecal coliform counts ranged between 3.8±1.2 and 6.8±2.4×102...

Journal of Pharmaceutical Research and Development & Practice, 2016

The bacteriological quality of water from River Lavun (lower part of River Kaduna), used by the p... more The bacteriological quality of water from River Lavun (lower part of River Kaduna), used by the populace of Bida and environ for domestic activities, irrigation and source of aquatic food was investigated. Water samples were collected from three different points along the river for six months. Using standard methods, heterotrophic plate count (HPC), faecal coliform count (FCC) and faecal streptococci counts (FSC) were determined while identification of specific contaminant was done using rapid test kits.

Journal of Pharmacy & Bioresources, 2021

Cancer and infectious diseases combined are leading cause of death and public health concern. In ... more Cancer and infectious diseases combined are leading cause of death and public health concern. In developing countries, about 80% of the populace depends on medicinal plants for their general health care needs including treatment of infectious diseases and cancer. Aloe schweinfurthii (Aloaceae) is a small medicinal herb that is commonly used for the treatment of cancerous and infectious diseases in South-West Nigeria. The focus of this study was to evaluate the growth inhibitory and antimicrobial activities of the herb. The rind of the herb was collected, air dried, pulverized and extracted into distilled methanol by cold maceration. The dried extract obtained was subjected to growth inhibitory and antimicrobial assays. The extract displayed concentration dependent growth inhibitory activity with IC50 of 484.7±2.16 and 1188±2.32μg/mL compared to cyclophosphamide with IC50 of 174.3±0.19 and 834.5±0.84 μg/mL in Sorghum bicolor radical and Allium cepa root growth inhibitory assays, resp...

Dhaka University Journal of Pharmaceutical Sciences, 2019

In order to authenticate and ascertain the various claim by the rural dwellers that depend on che... more In order to authenticate and ascertain the various claim by the rural dwellers that depend on chewing sticks for their oral hygiene and protection against innumerable diseases, the antibacterial activity of the roots of Fagara zanthoxyloides and Distemonanthus benthamianus were evaluated. Preliminary phytochemical screening was carried out using standard methods. In-vitro antibacterial activity of the methanol extracts of both plants was also carried out using the agar well diffusion method against standard strains of Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 25922, Salmonella typhii ATCC 14028, Citrobacter freundii ATCC 8090 and also some clinical isolates of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis at different concentrations and ratios. Preliminary phytochemical screening showed that the extracts contained alkaloids, saponin, tannins, steroids, flavonoids, anthraqu...

Sokoto Journal of Medical Laboratory Science, 2022

the hospital more than four time in a month were Medical and paramedical students are often 0.72 ... more the hospital more than four time in a month were Medical and paramedical students are often 0.72 (95% CI, 0.394-1.328) and 0.61 (95% CI, exposed to MRSA colonization and infection 0.325-1.136) times more likely to carry MRSA, during clinical postings. They may serve as respectively. The MRSA isolates were highly reservoirs or vector and occasionally as victims resistant to all the tested antibiotics (72-100 %). of MRSA cross-contamination. This study was The MRSA nasal carriage rate among medical designed to determine the rate of MRSA nasal and paramedical students of Usmanu Danfodiyo c a r r i a g e a m o n g a p p a r e n t l y h e a l t h y University Sokoto is high. The finding of this undergraduate medical students of Usmanu study has important implication on public health. Danfodiyo University Sokoto. A questionnaire Thus, urgent steps should be taken to improve was administered to collect demographic data infection control practices in the study area. and health history of the recruited participants.

Journal of Pharmacy & Bioresources, 2018

Bida axis of Niger State, Nigeria depends on River Lavun for its domestic and commercial activiti... more Bida axis of Niger State, Nigeria depends on River Lavun for its domestic and commercial activities especially for fishing, drinking, washing, transportation, irrigation and waste disposal, with potential impact on physicochemical and elemental qualities of the river water. The physicochemical parameters of the river water, namely: temperature, pH, alkalinity, conductivity, phosphate, nitrate, biochemical oxygen demand (BOD) and chemical oxygen demand (COD) evaluated were found to be within acceptable limit set by World Health Organization (WHO) and/or Nigeria Industrial Standard (NIS) while dissolved oxygen (DO) was above the limit. Elemental composition of the river water was also studied using atomic absorption spectrophotometer (AAS). Results of the elemental analysis showed that silver, cobalt, and lead were not detected, while the levels of iron, manganese, nickel, and cadmium, were above acceptable limit of drinking water set by WHO and/or NIS. Keywords: Physicochemical; Elemental, Water quality, River Lavun