Affifa Tahir Khan 6384-FSL/LLB/F21 - Academia.edu (original) (raw)
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Papers by Affifa Tahir Khan 6384-FSL/LLB/F21
Journal of the Dow University of Health Sciences, 2020
On the other hand, imaging devices like magnetic resonance imaging (MRI) are employed to evaluate... more On the other hand, imaging devices like magnetic resonance imaging (MRI) are employed to evaluate the iron chelation therapeutic effects based on signal intensity on T1 and T2 weighted sequences, as lower 8 signal intensity suggests iron overload. Such intervention expedites the assessment of iron levels in the body before the onset of dysfunction of organs and 10,11 hemosiderosis could set in. Many studies showed that beta thalassemia affects the neurological conditions of those individuals who suffer 12,15 from this disease. However, these neurological anomalies have not been fully compiled or discussed yet. In this article, we will discuss these neurological impairments caused by beta-thalassemia and their possible curative therapy to alleviate some of these conditions. EXTRAMEDULLARY HEMATOPOIESIS Extramedullary hematopoiesis (EMH) is a homeostatic phenomenon that arises among chronic anemic patients in which hematopoietic foci are formed other than bone marrow to compensate the circulatory 16-18 needs. In 1954, Gatto and their colleagues reported
Journal of the Dow University of Health Sciences, 2020
On the other hand, imaging devices like magnetic resonance imaging (MRI) are employed to evaluate... more On the other hand, imaging devices like magnetic resonance imaging (MRI) are employed to evaluate the iron chelation therapeutic effects based on signal intensity on T1 and T2 weighted sequences, as lower 8 signal intensity suggests iron overload. Such intervention expedites the assessment of iron levels in the body before the onset of dysfunction of organs and 10,11 hemosiderosis could set in. Many studies showed that beta thalassemia affects the neurological conditions of those individuals who suffer 12,15 from this disease. However, these neurological anomalies have not been fully compiled or discussed yet. In this article, we will discuss these neurological impairments caused by beta-thalassemia and their possible curative therapy to alleviate some of these conditions. EXTRAMEDULLARY HEMATOPOIESIS Extramedullary hematopoiesis (EMH) is a homeostatic phenomenon that arises among chronic anemic patients in which hematopoietic foci are formed other than bone marrow to compensate the circulatory 16-18 needs. In 1954, Gatto and their colleagues reported