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Papers by Dr Parveen Ahlawat

Research paper thumbnail of Role of neoadjuvant therapy in resectable pancreatic carcinoma: a review article

Annals of pancreatic cancer, May 1, 2024

Research paper thumbnail of PO-1541 Dosimetric impact of tumour regression in carcinoma cervix treated with radical IMRT

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of Effectiveness of Head-and-Neck Molecular Imaging Reporting and Data System Criterion in Head-and-Neck Squamous Cell Carcinoma PostConcurrent Chemoradiotherapy

Indian Journal of Nuclear Medicine, Dec 31, 2022

Research paper thumbnail of 921P Assessment of health-related quality of life in head and neck cancer patients treated with chemoradiation

Annals of Oncology, Sep 1, 2021

Research paper thumbnail of PO-0950 Comparison between two-dose levels versus three-dose levels IMRT in head and neck cancers

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-129: Definitive radiotherapy in oligometastatic head and neck cancers responding to systemic therapy

Radiotherapy and Oncology, Dec 1, 2019

Research paper thumbnail of PO-1028 Inter-correlations between various high-risk pathological factors in squamous cell carcinoma tongue

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0949 Comparison between simultaneous integrated boost IMRT and sequential IMRT in head and neck cancers

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0953 Impact of human papilloma virus on treatment outcomes in oropharyngeal cancer in India

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0977 Comparison of therapy outcomes between 2-dimensional radiotherapy and IMRT for early glottic cancer

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0981 Wide histological spectrum of sinonasal malignancies and survival outcomes - An Institutional review

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of Would Full-Dose Radiotherapy Benefit Patients With Synchronous Oligometastatic Head & Neck Squamous Cell Carcinoma

International Journal of Radiation Oncology Biology Physics, Nov 1, 2021

PURPOSE/OBJECTIVE(S) The incidence of de-novo metastatic head and neck (mHNC) has increased over ... more PURPOSE/OBJECTIVE(S) The incidence of de-novo metastatic head and neck (mHNC) has increased over time with the use of more sensitive metastatic work-up. With early diagnosis and better systemic therapies, aggressive management of mHNC has led to next most logical step in the management; use of definitive locoregional radiotherapy (d-RT) for patient responding to systemic therapy MATERIALS/METHODS: The institutional database was reviewed from January 2015 - March 2018, 5,483 HNC patients were isolated. Forty-nine patients were identified with de-novo mHNC, of which data was available for 31. Survival-analysis with endpoints of overall survival (OS) and progression free survival (PFS) was done. RESULTS With a median follow-up of 15 months, the median OS and PFS for the entire cohort was 15 and 7 months, respectively. Median PFS and OS of patients receiving d-RT vs no d-RT was 18 (range 14.97 - 21.03) months vs 5 (range 3.52 - 6.48) months, P = 0.005 and 38 (range 8.40 - 67.60) months vs 9 (range 4.56 - 13.45) months, P = 0.002, respectively. Patients with extra-pulmonary metastases had worse median OS of 21 (range 0 - 44.15) months, P = 0.047. CONCLUSION De-novo mHNC is a less often encountered diagnoses. Patients with extra-pulmonary metastases tend to do worse. However, patients who initially respond to chemotherapy fair better especially with d-RT. A prospective trial for such a clinical scenario would be unlikely and more retrospective evidence is needed for confirming OS and PFS advantage of using d-RT in such a setting.

Research paper thumbnail of PO-1140: Role of Functional Imaging in evaluation of Radiation Colitis

Radiotherapy and Oncology, 2020

Research paper thumbnail of PO-1865 Simultaneous integrated boost IMRT versus sequential IMRT in head and neck cancers

Radiotherapy and Oncology, 2021

Research paper thumbnail of PO-0979 Tumour volume as prognostic factor for recurrent head and neck cancers treated with reirradiation

Radiotherapy and Oncology, 2021

Research paper thumbnail of PO-0972 Pre-treatment haemoglobin as a surrogate marker for survival in head neck squamous cell carcinoma

Radiotherapy and Oncology, 2021

Research paper thumbnail of Image guided interstitial brachytherapy for locally advanced disease after external beam radiotherapy in a case of carcinoma cervix – our institutional experience

Asian journal of oncology, Jul 1, 2016

with CTRT in the patients of uterine cervix of a tertiary cancer care centre. Patients and Method... more with CTRT in the patients of uterine cervix of a tertiary cancer care centre. Patients and Methods: Retrospective study was performed in locally advanced/advance stage patients of cervix UTERI registered in the institute between years 2009 to 2013. Patients were included in the two groups, group A consists of 89 patients who have received NACT + RS and 67 patients in group B who have received CTRT. Clinical records were reviewed with particular reference to presenting complaint, clinical stage, response to the therapy, disease free survival and overall survival. Statistical analysis was done using SPSS version 22. Results: In the neoadjuvant group (group A) (n=89) the median age of patients was 53 years (range 31-80 years), most of the patients (70%) were presented with complaint of postmenopausal bleeding. Of the total patients, 69 (77.5%) underwent to radical surgery and 5 (8.5%) received radiotherapy after NACT. From 69 patients, who had undergone to surgery, 54 (78.3%) had also received radiation. The overall response to induction chemotherapy was 84%. In the chemo radiation group (group B) (n=65) median age was 56 years (33-75 years). Vaginal bleeding (34%) followed by postmenopausal bleeding (32%) was major presenting complaint in this group. Overall response to the complete treatment was 91%. The median follow up time was 14.3 months in group A and 12.2 months in group B. The disease free survival for NACT group was 32 months (95% CI 26.8-36.5) whereas for CTRT group it was 28 months (95% CI 23.5-33) with 12 and 13 recurrences per group (p = .226). In NACT group overall survival was 46.2 months (95% CI 44-48.3) and for CTRT group it was 38.3 months (95%CI 36.6-40) with 3 and 2 deaths per group (p=.883). Conclusion: Present study shows comparable results, with no difference in survival between both the groups. However, NACT + RS group had showed better disease free and overall survival than another group. Further studies should be performed with larger number of patients and longer duration of follow up.

Research paper thumbnail of Comparison of the outcomes between locally advanced cervical squamous cell carcinoma and adenocarcinoma patients treated with definitive chemoradiation

Asian journal of oncology, Jul 1, 2016

Comparison of the outcomes between locally advanced cervical squamous cell carcinoma and adenocar... more Comparison of the outcomes between locally advanced cervical squamous cell carcinoma and adenocarcinoma patients treated with definitive chemoradiation

Research paper thumbnail of Sinonasal teratocarcinosarcoma treated with surgery followed by volumetric modulated radiotherapy: a case report with review of literature

Radiation oncology journal, Dec 31, 2018

Surgical excision along with use of postoperative radiotherapy forms an integral management of si... more Surgical excision along with use of postoperative radiotherapy forms an integral management of sinonasal teratocarcinosarcoma (SNTCS). However, given the rarity of the tumor, no standardised guidelines, dose, technique and target delineation exist especially in the era of modern radiation delivery techniques. This is a case of 55-year-old male diagnosed as SNTCS treated with radical ethmoidectomy followed by volumetric modulated radiotherapy, showing good local control and acceptable toxicity profile.

Research paper thumbnail of Treatment Delay during Radiotherapy of Cancer Patients due to COVID-19 Pandemic

Asian Pacific Journal of Cancer Prevention, Jul 1, 2022

Haresh et al., 2020). The COVID-19 pandemic has affected oncology patients at many levels. Apart ... more Haresh et al., 2020). The COVID-19 pandemic has affected oncology patients at many levels. Apart from the psychological stress caused by a cancer diagnosis and COVID-19

Research paper thumbnail of Role of neoadjuvant therapy in resectable pancreatic carcinoma: a review article

Annals of pancreatic cancer, May 1, 2024

Research paper thumbnail of PO-1541 Dosimetric impact of tumour regression in carcinoma cervix treated with radical IMRT

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of Effectiveness of Head-and-Neck Molecular Imaging Reporting and Data System Criterion in Head-and-Neck Squamous Cell Carcinoma PostConcurrent Chemoradiotherapy

Indian Journal of Nuclear Medicine, Dec 31, 2022

Research paper thumbnail of 921P Assessment of health-related quality of life in head and neck cancer patients treated with chemoradiation

Annals of Oncology, Sep 1, 2021

Research paper thumbnail of PO-0950 Comparison between two-dose levels versus three-dose levels IMRT in head and neck cancers

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-129: Definitive radiotherapy in oligometastatic head and neck cancers responding to systemic therapy

Radiotherapy and Oncology, Dec 1, 2019

Research paper thumbnail of PO-1028 Inter-correlations between various high-risk pathological factors in squamous cell carcinoma tongue

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0949 Comparison between simultaneous integrated boost IMRT and sequential IMRT in head and neck cancers

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0953 Impact of human papilloma virus on treatment outcomes in oropharyngeal cancer in India

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0977 Comparison of therapy outcomes between 2-dimensional radiotherapy and IMRT for early glottic cancer

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of PO-0981 Wide histological spectrum of sinonasal malignancies and survival outcomes - An Institutional review

Radiotherapy and Oncology, Aug 1, 2021

Research paper thumbnail of Would Full-Dose Radiotherapy Benefit Patients With Synchronous Oligometastatic Head & Neck Squamous Cell Carcinoma

International Journal of Radiation Oncology Biology Physics, Nov 1, 2021

PURPOSE/OBJECTIVE(S) The incidence of de-novo metastatic head and neck (mHNC) has increased over ... more PURPOSE/OBJECTIVE(S) The incidence of de-novo metastatic head and neck (mHNC) has increased over time with the use of more sensitive metastatic work-up. With early diagnosis and better systemic therapies, aggressive management of mHNC has led to next most logical step in the management; use of definitive locoregional radiotherapy (d-RT) for patient responding to systemic therapy MATERIALS/METHODS: The institutional database was reviewed from January 2015 - March 2018, 5,483 HNC patients were isolated. Forty-nine patients were identified with de-novo mHNC, of which data was available for 31. Survival-analysis with endpoints of overall survival (OS) and progression free survival (PFS) was done. RESULTS With a median follow-up of 15 months, the median OS and PFS for the entire cohort was 15 and 7 months, respectively. Median PFS and OS of patients receiving d-RT vs no d-RT was 18 (range 14.97 - 21.03) months vs 5 (range 3.52 - 6.48) months, P = 0.005 and 38 (range 8.40 - 67.60) months vs 9 (range 4.56 - 13.45) months, P = 0.002, respectively. Patients with extra-pulmonary metastases had worse median OS of 21 (range 0 - 44.15) months, P = 0.047. CONCLUSION De-novo mHNC is a less often encountered diagnoses. Patients with extra-pulmonary metastases tend to do worse. However, patients who initially respond to chemotherapy fair better especially with d-RT. A prospective trial for such a clinical scenario would be unlikely and more retrospective evidence is needed for confirming OS and PFS advantage of using d-RT in such a setting.

Research paper thumbnail of PO-1140: Role of Functional Imaging in evaluation of Radiation Colitis

Radiotherapy and Oncology, 2020

Research paper thumbnail of PO-1865 Simultaneous integrated boost IMRT versus sequential IMRT in head and neck cancers

Radiotherapy and Oncology, 2021

Research paper thumbnail of PO-0979 Tumour volume as prognostic factor for recurrent head and neck cancers treated with reirradiation

Radiotherapy and Oncology, 2021

Research paper thumbnail of PO-0972 Pre-treatment haemoglobin as a surrogate marker for survival in head neck squamous cell carcinoma

Radiotherapy and Oncology, 2021

Research paper thumbnail of Image guided interstitial brachytherapy for locally advanced disease after external beam radiotherapy in a case of carcinoma cervix – our institutional experience

Asian journal of oncology, Jul 1, 2016

with CTRT in the patients of uterine cervix of a tertiary cancer care centre. Patients and Method... more with CTRT in the patients of uterine cervix of a tertiary cancer care centre. Patients and Methods: Retrospective study was performed in locally advanced/advance stage patients of cervix UTERI registered in the institute between years 2009 to 2013. Patients were included in the two groups, group A consists of 89 patients who have received NACT + RS and 67 patients in group B who have received CTRT. Clinical records were reviewed with particular reference to presenting complaint, clinical stage, response to the therapy, disease free survival and overall survival. Statistical analysis was done using SPSS version 22. Results: In the neoadjuvant group (group A) (n=89) the median age of patients was 53 years (range 31-80 years), most of the patients (70%) were presented with complaint of postmenopausal bleeding. Of the total patients, 69 (77.5%) underwent to radical surgery and 5 (8.5%) received radiotherapy after NACT. From 69 patients, who had undergone to surgery, 54 (78.3%) had also received radiation. The overall response to induction chemotherapy was 84%. In the chemo radiation group (group B) (n=65) median age was 56 years (33-75 years). Vaginal bleeding (34%) followed by postmenopausal bleeding (32%) was major presenting complaint in this group. Overall response to the complete treatment was 91%. The median follow up time was 14.3 months in group A and 12.2 months in group B. The disease free survival for NACT group was 32 months (95% CI 26.8-36.5) whereas for CTRT group it was 28 months (95% CI 23.5-33) with 12 and 13 recurrences per group (p = .226). In NACT group overall survival was 46.2 months (95% CI 44-48.3) and for CTRT group it was 38.3 months (95%CI 36.6-40) with 3 and 2 deaths per group (p=.883). Conclusion: Present study shows comparable results, with no difference in survival between both the groups. However, NACT + RS group had showed better disease free and overall survival than another group. Further studies should be performed with larger number of patients and longer duration of follow up.

Research paper thumbnail of Comparison of the outcomes between locally advanced cervical squamous cell carcinoma and adenocarcinoma patients treated with definitive chemoradiation

Asian journal of oncology, Jul 1, 2016

Comparison of the outcomes between locally advanced cervical squamous cell carcinoma and adenocar... more Comparison of the outcomes between locally advanced cervical squamous cell carcinoma and adenocarcinoma patients treated with definitive chemoradiation

Research paper thumbnail of Sinonasal teratocarcinosarcoma treated with surgery followed by volumetric modulated radiotherapy: a case report with review of literature

Radiation oncology journal, Dec 31, 2018

Surgical excision along with use of postoperative radiotherapy forms an integral management of si... more Surgical excision along with use of postoperative radiotherapy forms an integral management of sinonasal teratocarcinosarcoma (SNTCS). However, given the rarity of the tumor, no standardised guidelines, dose, technique and target delineation exist especially in the era of modern radiation delivery techniques. This is a case of 55-year-old male diagnosed as SNTCS treated with radical ethmoidectomy followed by volumetric modulated radiotherapy, showing good local control and acceptable toxicity profile.

Research paper thumbnail of Treatment Delay during Radiotherapy of Cancer Patients due to COVID-19 Pandemic

Asian Pacific Journal of Cancer Prevention, Jul 1, 2022

Haresh et al., 2020). The COVID-19 pandemic has affected oncology patients at many levels. Apart ... more Haresh et al., 2020). The COVID-19 pandemic has affected oncology patients at many levels. Apart from the psychological stress caused by a cancer diagnosis and COVID-19