Ahmadreza Assareh - Academia.edu (original) (raw)

Papers by Ahmadreza Assareh

Frontiers in Nutrition

BackgroundUltra-processed foods (UPF) consumption may affect the risk of PCAD through affecting c... more BackgroundUltra-processed foods (UPF) consumption may affect the risk of PCAD through affecting cardio metabolic risk factors. This study aimed to evaluate the association between UPFs consumption and premature coronary artery disease (PCAD).MethodsA case–control study was conducted on 2,354 Iranian adults (≥ 19 years). Dietary intake was assessed using a validated 110-item food frequency questionnaire (FFQ) and foods were classified based on the NOVA system, which groups all foods according to the nature, extent and purposes of the industrial processes they undergo. PCAD was defined as having an stenosis of at least single coronary artery equal and above 75% or left main coronary of equal or more than 50% in women less than 70 and men less than 60 years, determined by angiography. The odds of PCAD across the tertiles of UPFs consumption were assessed by binary logistic regression.ResultsAfter adjustment for potential confounders, participants in the top tertile of UPFs were twice a...

BMC Cardiovascular Disorders

Background Diverse ethnic groups that exist in Iran may differ regarding the risk factors such as... more Background Diverse ethnic groups that exist in Iran may differ regarding the risk factors such as hypertension, hyperlipidemia, dyslipidemia, diabetes mellitus, and family history of non-communicable disease. Premature Coronary Artery Disease (PCAD) is more endemic in Iran than before. This study sought to assess the association between ethnicity and lifestyle behaviors in eight major Iranian ethnic groups with PCAD. Methods In this study, 2863 patients aged ≤ 70 for women and ≤ 60 for men who underwent coronary angiography were recruited in a multi-center framework. All the patients’ demographic, laboratory, clinical, and risk factor data were retrieved. Eight large ethnicities in Iran, including the Farses, the Kurds, the Turks, the Gilaks, the Arabs, the Lors, the Qashqai, and the Bakhtiari were evaluated for PCAD. Different lifestyle components and having PCAD were compared among the ethnical groups using multivariable modeling. Results The mean age of the 2863 patients particip...

International Journal of Cardiology Cardiovascular Risk and Prevention

Cardiovascular & Hematological Disorders-Drug Targets, 2020

Background & Objective: Acute renal failure (AKI) is one of the most important complications of P... more Background & Objective: Acute renal failure (AKI) is one of the most important complications of PCI. Due to delay in creatinine increase, we need specific factors to detect AKI earlier. The aim of this study is to evaluate the valuable factors by focusing on HFAB-P that can be predictive for AKI after Percutaneous Coronary Intervention (PCI). Methods: This prospective study was performed on 95 patients (55 males and 44 females aged between 49-78 years) under PCI in Golestan and Imam Khomeini hospitals in Ahvaz. Patients were divided into three groups based on the development of AKI after the procedure: no AKI, severe AKI (doubling of serum creatinine or needing dialysis) and any type of AKI (increased creatinine ≥ 0/3 mg/dl or a 50% increase in the means of 1/5 times serum creatinine). The demographic and clinical characteristics of the patients, the medical history and the results of the HFABP marker, GFR, and creatinine before and after PCI were evaluated for all patients. Results...

Journal of Biology and Today's World, 2014

To determine short-term (in-hospital) outcome and complications of surgical and interventional pr... more To determine short-term (in-hospital) outcome and complications of surgical and interventional procedures performed for patients with coarctation of the aorta (CoA) in the age range of 5 to 25 year. Medical records of 64 patients (48 males and 16 females) with CoA who underwent surgical treatment March 2002 to March 2012 were reviewed. Surgical operation was done for 26 patients and interventional procedures were done for 18 cases. The data gathered included type of CoA, anatomic type, hospitalization duration, and complications occurred during hospitalization such as hypertension, persistent CoA, surgical wound infection, and death. Both surgery and interventional procedures restored pre-operative hypertension significantly. The safest method regarding in-hospital complications was balloon angioplasty (1 patient had systemic hypertension after the procedure, 25%) followed by Dacron patch (3 cases had hypertension and one patient had persistent coarctation). However, no significant difference was observed between different surgical and interventional procedures. Pre-operative systolic blood pressure, age group, peak systolic gradient, simple or complex CoA, discrete or segmental CoA had no significant relationship with in-hospital complications/outcome. In conclusion, we suggest considering all aspects of patients with CoA to choose the best surgical treatment. Based on our experience balloon angioplasty and Dacron patch were the safest method with acceptable rate of restoration in blood pressure during in-hospital follow-up period.

Journal of Research in Medical Sciences

Jundishapur Journal of Chronic Disease Care, 2022

Background: The awareness of the risk factors of atherosclerosis and attempts to correct and cont... more Background: The awareness of the risk factors of atherosclerosis and attempts to correct and control them can effectively reduce the risk of complications. Objectives: This study was performed to evaluate the risk factors for routine atherosclerosis in patients with symptoms of heart disease in the Arab race, compared to those of Lor patients. Methods: This descriptive-analytical study was conducted on 200 patients with symptoms of heart disease. A food frequency questionnaire was used for data collection. Results: Out of 200 patients, 101 (51.5%) and 99 (48.5%) participants were Lor and Arab, respectively. Significant differences were observed between the two races for cholesterol and fasting blood sugar levels (P < 0.05). Additionally, no significant difference was observed between different quarters of following dietary patterns and lipid-glucose factors (P > 0.05). Conclusions: Risk factors for cardiovascular diseases, such as atherosclerosis, are multifactorial. Various f...

ARYA atherosclerosis, 2021

BACKGROUND: With the onset of the coronavirus disease-2019 (COVID-19) pandemic, hospitalization a... more BACKGROUND: With the onset of the coronavirus disease-2019 (COVID-19) pandemic, hospitalization and treatment of non-covid patients decreased worldwide. The aim of this study is to evaluate the admission and treatment of patients with coronary artery diseases (CADs) by examining coronary Cath labs activities in some centers of Iran during the COVID-19 period. METHODS: A retrospective, multi-center survey was conducted in four cites in Iran which participated in National Persian Registry Of CardioVascular diseasE (N-PROVE). Two periods of COVID-19 occurrence peak in Iran were compared with the same date in 2019. Information was collected on the number of diagnostic and therapeutic coronary catheterizations in both stable ischemic heart diseases (SIHDs) and acute coronary syndrome (ACS) settings. RESULTS: In the first peak of COVID-19 pandemic, coronary angiographies and angioplasties decreased by 37 and 38% compared to the same period in 2019, respectively. The most common indication...

Current Problems in Cardiology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Indian Journal of Pharmacology, 2016

Carvedilol is a nonselective third generation β-blocker that does not display the negative effect... more Carvedilol is a nonselective third generation β-blocker that does not display the negative effects of traditional β-blockers. Regarding the antioxidant, anti-inflammatory and distinct metabolic properties of carvedilol which are similar to that of high-density lipoprotein (HDL) and paraoxonase 1 (PON1), the present study intends to investigate the effects of carvedilol treatment on malondialdehyde (MDA) and soluble lectin-like ox-low-density lipoprotein (LDL) receptor (sLOX-1) as markers of oxidative stress in association to lipid profiles, apolipoproteins (apo), and PON1 activity in hypertensive patients. This clinical trial study was performed on forty patients with mild to moderate essential hypertension. Subjects were studied before and after 2 months treatment with carvedilol, 25 mg daily. Lipids and lipoproteins were measured using a biochemistry analyzer. PON and arylesterase activity were assayed using paraoxon and phenyl acetate as substrates, respectively. MDA was quantified using a chemical colorimetric assay. ELISA was used to measure sLOX-1. Our results showed that carvedilol treatment decreased systolic and diastolic blood pressure as much as forty and 16 mmHg, respectively (P &amp;amp;amp;amp;amp;lt; 0.001). It also increased HDL, total cholesterol, and serum PON1 activity (P &amp;amp;amp;amp;amp;lt; 0.05), but the levels of triglyceride, LDL, apo A-I, and apo B did not significantly change. There was an inverse correlation between serum PON1 activity and serum MDA. This study confirmed the antihypertensive effect of the drug and its beneficial metabolic effects through augmenting HDL and PON1 activity. We propose that the antioxidant effects of carvedilol can be partially attributed to increased PON-1 activity.

World Journal of Cardiovascular Diseases, 2013

European Heart Journal, 2006

Aims To clarify the major features of the apical ballooning syndrome, we performed a systematic r... more Aims To clarify the major features of the apical ballooning syndrome, we performed a systematic review of the existing literature. Methods and results Review of all relevant case series using the MEDLINE and EMBASE databases resulted in the identification of 14 studies. These studies suggest that the apical ballooning syndrome accounts for 2.0% of ST-segment elevation infarcts, with most cases described in post-menopausal women. The most common clinical presentations are chest pain and dyspnoea, reported in 67.8 and 17.8% of the patients, respectively. Cardiogenic shock (4.2% of the patients) and ventricular fibrillation (1.5%) were not infrequent. ST-segment elevation was reported in 81.6% of the patients, Twave abnormalities in 64.3%, and Q waves in 31.8%. Cardiac biomarkers were usually mildly elevated, as reported in 86.2% of the patients. Typically, patients had left ventricular (LV) dysfunction on admission, with mean ejection fraction ranging from 20 to 49%. However, over a period of days to weeks, all patients experienced dramatic improvement in LV function. The onset of symptoms was often preceded by emotional (26.8%) or physical stress (37.8%). Norepinephrine concentration was elevated in 74.3% of the patients. Prognosis was generally excellent, with full recovery in most patients. In-hospital mortality was 1.1%. Only 3.5% of the patients experienced a recurrence. Conculsion Clinicians should consider this syndrome in the differential diagnosis of patients presenting with chest pain, especially in post-menopausal women with a recent history of emotional or physical stress.

ARYA atherosclerosis, 2012

Acute chest pain is a common symptom among patients presenting to emergency wards. Identification... more Acute chest pain is a common symptom among patients presenting to emergency wards. Identification and admission of patients with real acute coronary syndrome and preventing the hospitalization of people with false diagnosis of coronary syndrome are the most important tasks in emergency wards. The purpose of this study was to investigate the usefulness of designing a special chest pain unit in emergency department of Imam Khomeini Hospital (Ahvaz, Iran). The patients with markers of ongoing cardiac ischemia underwent selective coronary angiography. The chest pain unit protocol was applied to selected patients with no definite evidence of acute coronary syndrome or alternative pathology. The protocol consisted of twelve hours of observation and serial 12-lead electrocardiography, transthoracic echocardiography, and biochemical testing followed by an exercise treadmill test. We compared the number of patients who were discharged after work up, discharged themselves against medical advi...

Background and Objective: Erectile dysfunction (ED) is a common medical disorder which is more pr... more Background and Objective: Erectile dysfunction (ED) is a common medical disorder which is more prevalent in patients with coronary artery disease (CAD). Several mutual risk factors exist between ED and CAD; therefore ED has been recognized as CAD risk equivalent. The purpose of this study was to assess internal pudendal artery angiographic findings in patients with CAD and ED. Subjects and Methods: Forty male candidate for coronary artery angiography who suffered from ED were included in this study. The participants' ED was evaluated by Sexual Health Inventory for Men (SHIM), a five question version of the International Index of Erectile Function (IIEF) questionnaire. After coronary artery angiography, in the same session patients underwent selective pelvic artery angiography. Results: A relationship was seen between the severity of ED and the number of coronary arteries with atherosclerosis (P=0.028). Furthermore, a direct relationship was also seen between the probability of a...

1. Cardiovascular Research Center, Golestan Hospital , Ahvaz Jundishapur University of Medical Sc... more 1. Cardiovascular Research Center, Golestan Hospital , Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran 2. Department of Oral Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran 3. Diabetes Research Center, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran 4. Prevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences (RIES), Shahid Beheshti University of Medical Sciences, Tehran, Iran

Asian Journal of Pharmaceutical and Clinical Research

Objective: Pentraxin3 (PTX3) is an inflammatory single-phase mononuclear polysorbate glycoprotei... more Objective: Pentraxin3 (PTX3) is an inflammatory single-phase mononuclear polysorbate glycoprotein, synthesized by endothelial, macrophages, and mildew cells; based on reports and research findings, it is also believed to be synthesized in the tissue of atherosclerotic lesions of arterial arteries. Therefore, PTX3 can be considered as a more specific marker for atherosclerosis. The present study examines the relationship between PTX3 serum levels and coronary angiography findings.Methods: A total of 100 patients with stable cardiac status under elective coronary angiography were studied. Meanwhile, serum levels of PTX3 were measured, along with coronary angiography, in these patients. Finally, the relationship between the serum level of this marker and the severity of the angiographic findings of these individuals was compared and contrasted.Results: out of 100 patients examined in the present study, 57 subjects (57.6%) were male and 42 subjects (42.4%) were female. The mean age of ...

International Journal of Cardiovascular Research, 2012

Noninvasive Coronary Artery Calcium Scoring: Do We Always Need Invasive Computed Tomographic Angi... more Noninvasive Coronary Artery Calcium Scoring: Do We Always Need Invasive Computed Tomographic Angiography for Diagnostic Purposes? The coronary artery disease (CAD) epidemic has emerged in the developing countries during the past two to three decades. It, however, has attracted less comment and little public health response, even within these countries. At present, developing countries are not widely recognized to contribute a greater share to the global burden of CAD than the developed countries. The most common cause of CAD is atherosclerosis.

Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences, 2012

Background: Definitions of chronic kidney disease (CKD) in many catheterization laboratories have... more Background: Definitions of chronic kidney disease (CKD) in many catheterization laboratories have relied on the serum creatinine (Scr) rather than glomerular filtration rate (GFR). Regarding that CKD is the primary predisposing factor for contrast induced nephropathy (CIN), we compared the sensitivity of calculated GFR by 24-h Urine creatinine with Cockcroft-Gault (CG) equation and Scr level to define at risk patients for CIN who were undergone coronary angiography (CAG). Materials and Methods: Two hundred fifty four subjects who were candidate for CAG and had normal creatinine level were enrolled. Before CAG, GFR was calculated from a 24-h urine collection, CG equation and a single Scr sample regarding to previously described protocol. Contrast volume used for each case <100 ml. CIN was defined as a 0.5 mg/dL or 25% elevation in the Scr. Results: CIN occurred in 10.6%. Baseline GFR, the volume of contrast agent, and diabetes were the independent risk factors for CIN. GFR was les...

ABSTRACT The aim of this study was examine the trend in risk of coronary artery Disease (CAD) con... more ABSTRACT The aim of this study was examine the trend in risk of coronary artery Disease (CAD) consider age-differencein the hospitals of Ahvaz Jundishapur University of medical Sciences. Methods: we had invited 317 patients in 2003 and 333 patients in 2012 with coronary artery disease (CAD) and candidates for angioplasty at hospitals of Ahvaz Jundishapur University of medical Sciences in Ahvaz city, Iran. Data has entered and analyzed by SPSS (version 21), and using descriptive statistic test. Results:The results of this study has shown that prevalence of risk factors except smoking almost has increase in female than male in 2003 as well as 2012, also the data has shown most of risk factors has come down except of diabetes. Conclusion: This data has shown that prevalence of diabetes in coronary artery Disease (CAD) patients has increased from 2003 to 2012, so it may require urgent decision making to national control program of non-communication disease in Iran.