Ahmed Adeel - Academia.edu (original) (raw)
Papers by Ahmed Adeel
i-manager’s Journal on Management, 2016
Tropical and geographical medicine, 1987
Acute intraperitoneal rupture is a rather rare complication of hepatic hydatid cysts; anaphylaxis... more Acute intraperitoneal rupture is a rather rare complication of hepatic hydatid cysts; anaphylaxis and sudden death have frequently been reported in such cases. In the present report we are presenting a case of acute traumatic intraperitoneal rupture of a huge hydatid cyst to which the patient showed no hypersensitivity reactions.
The Journal of tropical medicine and hygiene, 1988
Two hundred and ninety-six individuals of whom 126 were children and 170 adults with positive sto... more Two hundred and ninety-six individuals of whom 126 were children and 170 adults with positive stool for Schistosoma mansoni were randomly given oxamniquine treatment in a dose of either 20, 40 or 60 mg/kg body wt. They were followed in the field for ova excretion at 1, 3 and 6 months for adults and at 1, 3, 6 and 8 months for children. The cure rates in adults at 6 months are 93%, 87% and 73% for the 60, 40, 20 mg/kg-1 treatments in order. For children the cure rates at 6 months are 36%, 58% and 63% and at 8 months are 16%, 21% and 26% for corresponding doses. There is no difference in egg reduction for those not cured between the three treatments at 6 months. It is concluded that oxamniquine need not be given in the previously recommended 60 mg/kg body wt. A choice between 40 and 20 mg/kg body wt is suggested with the 40 mg/kg body wt to be reserved for individuals leaving the endemic area, and the 20 mg/kg body wt for those continuing to stay there with substantial exposure for re...
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ), 1989
Hawata District (Kassala Province) is one of the known endemic areas for visceral leishmaniasis i... more Hawata District (Kassala Province) is one of the known endemic areas for visceral leishmaniasis in Sudan. The co-endemicity with malaria, enteric fever, tuberculosis and brucellosis together with the limited medical laboratory facilities, rendered differential diagnosis of visceral leishmaniasis in this area, rather difficult. Two-hundred and three serum samples, including 49 collected from patients treated earlier as visceral leishmaniasis cases, were tested in a developed direct agglutination test (DAT). 100% concordance was found between the DAT results and the parasitological diagnosis in 40 confirmed cases. In nine unconfirmed, however highly suspected cases, the DAT results indicated visceral leishmaniasis. Significant improvements in the condition of those nine patients was observed during the therapeutic test and later on after a full course of treatment with sodium antimony gluconate (pentostam). DAT titres in the other serum samples (154), collected from patients with mala...
Tropical Medicine & International Health, 2008
objective To test the hypothesis that artesunate plus amodiaquine (ASAQ) is as effective as artem... more objective To test the hypothesis that artesunate plus amodiaquine (ASAQ) is as effective as artemether-lumefantrine (AL) in the treatment of acute uncomplicated malaria in Nigerian children. methods In an open label, randomized controlled clinical trial, children aged 6 months to 10 years were randomized to receive artesunate (4 mg ⁄ kg daily) plus amodiaquine (10 mg ⁄ kg daily) or AL (5-14 kg, one tablet; 15-24 kg, two tablets and 25-34 kg, three tablets twice daily). Both drug regimens were given for 3 days and follow-up was for 28 days. results A total of 132 children (66 in each group) were randomized to receive either ASAQ or AL. Day 28 cure rates in the per protocol (PP) population were 93% for ASAQ and 95% for AL (OR = 0.71, 95% CI = 0.12-3.99, q = 0.66). Using Kaplan-Meier product-limit estimates of failure, the median survival time for ASAQ was 21 days and for AL 28 days (P = 0.294). PCR corrected day 28 cure rate for PP populations were 98.4% for ASAQ and 100% for AL. Both drugs were well-tolerated. conclusion ASAQ is as effective as AL and both combinations were efficacious and safe. keywords co-artemether, artesunate plus amodiaquine, childhood, malaria, Nigeria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1993
Medical Education, 1998
Student assessment in community settings presents problems for medical teachers, e.g. dif®culties... more Student assessment in community settings presents problems for medical teachers, e.g. dif®culties in assessing the contribution of individual members to group work, and lack of test standardization due to varying ®eld conditions. The Faculty of Medicine, University of Gezira, Sudan is a community-oriented, community-based medical school which has adopted a comprehensive approach to student assessment in community settings using various methods, including peer assessment, a supervisory checklist, community feedback, reports from students, short essay questions (SEQs) and multiple choice questions (MCQs). Each method focuses on a speci®c aspect of the objectives of the community-based programme and is weighted in the ®nal grade according to the extent to which objectives were covered. This assessment programme contrasts with the conventional teacher-centred approach, and is continuously monitored and improved using a variety of sources of information. A total of 105 students participated in a study designed to measure the reliability and validity of this approach. The reliability of the methods was tested by computing the alpha co-ef®cient and was found to range between 0á77 and 0á92. This was considered acceptable. The validity of the instruments was examined using con®rmatory factor analysis, and their content validity was reviewed. The results show that the comprehensive approach used is fairly valid. It is suggested that the University's approach is successful in solving some of the problems of student assessment in community settings.
Sudanese Journal of Paediatrics, 2020
Coronavirus disease 2019 (COVID-19) is now spreading as a pandemic ravaging the whole world. In t... more Coronavirus disease 2019 (COVID-19) is now spreading as a pandemic ravaging the whole world. In the absence of a vaccine and an effective antiviral chemotherapy, there is currently an intense global interest in repositioning chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) to combat the pandemic. CQ has been used for decades for the treatment and prophylaxis against malaria in endemic countries. It is readily available and has also been manufactured in these countries. CQ is cheap, stable under field conditions and has been well tolerated as an antimalarial. This experience could be adapted to deploy CQ or HCQ for prophylaxis or treatment of COVID19 if strong evidence could be generated for these uses. We believe that well-designed drug trials should be initiated in malaria-endemic countries, taking into account the local context of the epidemic and the capacity of the health system in combating it. In this paper, we are presenting the current status of evidence for using CQ and HCQ against COVID19.
i-manager’s Journal on Management, 2016
Tropical and geographical medicine, 1987
Acute intraperitoneal rupture is a rather rare complication of hepatic hydatid cysts; anaphylaxis... more Acute intraperitoneal rupture is a rather rare complication of hepatic hydatid cysts; anaphylaxis and sudden death have frequently been reported in such cases. In the present report we are presenting a case of acute traumatic intraperitoneal rupture of a huge hydatid cyst to which the patient showed no hypersensitivity reactions.
The Journal of tropical medicine and hygiene, 1988
Two hundred and ninety-six individuals of whom 126 were children and 170 adults with positive sto... more Two hundred and ninety-six individuals of whom 126 were children and 170 adults with positive stool for Schistosoma mansoni were randomly given oxamniquine treatment in a dose of either 20, 40 or 60 mg/kg body wt. They were followed in the field for ova excretion at 1, 3 and 6 months for adults and at 1, 3, 6 and 8 months for children. The cure rates in adults at 6 months are 93%, 87% and 73% for the 60, 40, 20 mg/kg-1 treatments in order. For children the cure rates at 6 months are 36%, 58% and 63% and at 8 months are 16%, 21% and 26% for corresponding doses. There is no difference in egg reduction for those not cured between the three treatments at 6 months. It is concluded that oxamniquine need not be given in the previously recommended 60 mg/kg body wt. A choice between 40 and 20 mg/kg body wt is suggested with the 40 mg/kg body wt to be reserved for individuals leaving the endemic area, and the 20 mg/kg body wt for those continuing to stay there with substantial exposure for re...
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ), 1989
Hawata District (Kassala Province) is one of the known endemic areas for visceral leishmaniasis i... more Hawata District (Kassala Province) is one of the known endemic areas for visceral leishmaniasis in Sudan. The co-endemicity with malaria, enteric fever, tuberculosis and brucellosis together with the limited medical laboratory facilities, rendered differential diagnosis of visceral leishmaniasis in this area, rather difficult. Two-hundred and three serum samples, including 49 collected from patients treated earlier as visceral leishmaniasis cases, were tested in a developed direct agglutination test (DAT). 100% concordance was found between the DAT results and the parasitological diagnosis in 40 confirmed cases. In nine unconfirmed, however highly suspected cases, the DAT results indicated visceral leishmaniasis. Significant improvements in the condition of those nine patients was observed during the therapeutic test and later on after a full course of treatment with sodium antimony gluconate (pentostam). DAT titres in the other serum samples (154), collected from patients with mala...
Tropical Medicine & International Health, 2008
objective To test the hypothesis that artesunate plus amodiaquine (ASAQ) is as effective as artem... more objective To test the hypothesis that artesunate plus amodiaquine (ASAQ) is as effective as artemether-lumefantrine (AL) in the treatment of acute uncomplicated malaria in Nigerian children. methods In an open label, randomized controlled clinical trial, children aged 6 months to 10 years were randomized to receive artesunate (4 mg ⁄ kg daily) plus amodiaquine (10 mg ⁄ kg daily) or AL (5-14 kg, one tablet; 15-24 kg, two tablets and 25-34 kg, three tablets twice daily). Both drug regimens were given for 3 days and follow-up was for 28 days. results A total of 132 children (66 in each group) were randomized to receive either ASAQ or AL. Day 28 cure rates in the per protocol (PP) population were 93% for ASAQ and 95% for AL (OR = 0.71, 95% CI = 0.12-3.99, q = 0.66). Using Kaplan-Meier product-limit estimates of failure, the median survival time for ASAQ was 21 days and for AL 28 days (P = 0.294). PCR corrected day 28 cure rate for PP populations were 98.4% for ASAQ and 100% for AL. Both drugs were well-tolerated. conclusion ASAQ is as effective as AL and both combinations were efficacious and safe. keywords co-artemether, artesunate plus amodiaquine, childhood, malaria, Nigeria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1993
Medical Education, 1998
Student assessment in community settings presents problems for medical teachers, e.g. dif®culties... more Student assessment in community settings presents problems for medical teachers, e.g. dif®culties in assessing the contribution of individual members to group work, and lack of test standardization due to varying ®eld conditions. The Faculty of Medicine, University of Gezira, Sudan is a community-oriented, community-based medical school which has adopted a comprehensive approach to student assessment in community settings using various methods, including peer assessment, a supervisory checklist, community feedback, reports from students, short essay questions (SEQs) and multiple choice questions (MCQs). Each method focuses on a speci®c aspect of the objectives of the community-based programme and is weighted in the ®nal grade according to the extent to which objectives were covered. This assessment programme contrasts with the conventional teacher-centred approach, and is continuously monitored and improved using a variety of sources of information. A total of 105 students participated in a study designed to measure the reliability and validity of this approach. The reliability of the methods was tested by computing the alpha co-ef®cient and was found to range between 0á77 and 0á92. This was considered acceptable. The validity of the instruments was examined using con®rmatory factor analysis, and their content validity was reviewed. The results show that the comprehensive approach used is fairly valid. It is suggested that the University's approach is successful in solving some of the problems of student assessment in community settings.
Sudanese Journal of Paediatrics, 2020
Coronavirus disease 2019 (COVID-19) is now spreading as a pandemic ravaging the whole world. In t... more Coronavirus disease 2019 (COVID-19) is now spreading as a pandemic ravaging the whole world. In the absence of a vaccine and an effective antiviral chemotherapy, there is currently an intense global interest in repositioning chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) to combat the pandemic. CQ has been used for decades for the treatment and prophylaxis against malaria in endemic countries. It is readily available and has also been manufactured in these countries. CQ is cheap, stable under field conditions and has been well tolerated as an antimalarial. This experience could be adapted to deploy CQ or HCQ for prophylaxis or treatment of COVID19 if strong evidence could be generated for these uses. We believe that well-designed drug trials should be initiated in malaria-endemic countries, taking into account the local context of the epidemic and the capacity of the health system in combating it. In this paper, we are presenting the current status of evidence for using CQ and HCQ against COVID19.